KEGG   Canis lupus dingo (dingo): 112659290
Entry
112659290         CDS       T08371                                 
Symbol
RPS6KB2
Name
(RefSeq) ribosomal protein S6 kinase beta-2 isoform X1
  KO
K04688  ribosomal protein S6 kinase beta [EC:2.7.11.1]
Organism
clud  Canis lupus dingo (dingo)
Pathway
clud01521  EGFR tyrosine kinase inhibitor resistance
clud01522  Endocrine resistance
clud04012  ErbB signaling pathway
clud04066  HIF-1 signaling pathway
clud04140  Autophagy - animal
clud04150  mTOR signaling pathway
clud04151  PI3K-Akt signaling pathway
clud04152  AMPK signaling pathway
clud04211  Longevity regulating pathway
clud04213  Longevity regulating pathway - multiple species
clud04350  TGF-beta signaling pathway
clud04371  Apelin signaling pathway
clud04666  Fc gamma R-mediated phagocytosis
clud04714  Thermogenesis
clud04910  Insulin signaling pathway
clud04931  Insulin resistance
clud05163  Human cytomegalovirus infection
clud05165  Human papillomavirus infection
clud05170  Human immunodeficiency virus 1 infection
clud05200  Pathways in cancer
clud05205  Proteoglycans in cancer
clud05207  Chemical carcinogenesis - receptor activation
clud05210  Colorectal cancer
clud05212  Pancreatic cancer
clud05221  Acute myeloid leukemia
clud05224  Breast cancer
clud05225  Hepatocellular carcinoma
clud05226  Gastric cancer
clud05231  Choline metabolism in cancer
clud05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:clud00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    112659290 (RPS6KB2)
   04350 TGF-beta signaling pathway
    112659290 (RPS6KB2)
   04371 Apelin signaling pathway
    112659290 (RPS6KB2)
   04066 HIF-1 signaling pathway
    112659290 (RPS6KB2)
   04151 PI3K-Akt signaling pathway
    112659290 (RPS6KB2)
   04152 AMPK signaling pathway
    112659290 (RPS6KB2)
   04150 mTOR signaling pathway
    112659290 (RPS6KB2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    112659290 (RPS6KB2)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    112659290 (RPS6KB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    112659290 (RPS6KB2)
  09149 Aging
   04211 Longevity regulating pathway
    112659290 (RPS6KB2)
   04213 Longevity regulating pathway - multiple species
    112659290 (RPS6KB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    112659290 (RPS6KB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112659290 (RPS6KB2)
   05205 Proteoglycans in cancer
    112659290 (RPS6KB2)
   05207 Chemical carcinogenesis - receptor activation
    112659290 (RPS6KB2)
   05231 Choline metabolism in cancer
    112659290 (RPS6KB2)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    112659290 (RPS6KB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    112659290 (RPS6KB2)
   05212 Pancreatic cancer
    112659290 (RPS6KB2)
   05225 Hepatocellular carcinoma
    112659290 (RPS6KB2)
   05226 Gastric cancer
    112659290 (RPS6KB2)
   05221 Acute myeloid leukemia
    112659290 (RPS6KB2)
   05224 Breast cancer
    112659290 (RPS6KB2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    112659290 (RPS6KB2)
   05163 Human cytomegalovirus infection
    112659290 (RPS6KB2)
   05165 Human papillomavirus infection
    112659290 (RPS6KB2)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    112659290 (RPS6KB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    112659290 (RPS6KB2)
   01522 Endocrine resistance
    112659290 (RPS6KB2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:clud01001]
    112659290 (RPS6KB2)
Enzymes [BR:clud01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     112659290 (RPS6KB2)
Protein kinases [BR:clud01001]
 Serine/threonine kinases: AGC group
  RSK family [OT]
   112659290 (RPS6KB2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_C Pkinase_fungal Kinase-like ABC1 Seadorna_VP7
Other DBs
NCBI-GeneID: 112659290
NCBI-ProteinID: XP_025301674
Ensembl: ENSCAFG00020001528
LinkDB
Position
18:complement(49974300..49979873)
AA seq 516 aa
MRHWRARPRSQSDSVRLPPPRPPGCQSERGQARQGPAGPAPLWRPCLTWTWRRRKAARAS
QSSAPRPVGHCEEVELTETSVNLGPERIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGK
IYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGG
ELFTHLEREGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLNSQGHIKLTDFG
LCKESIHEGAVTHTFCGTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSASPASWPP
FTAENRKKTMDKIIKGKLTLPPYLTPDARDLVKKFLKRNPSQRIGGGPGDSADVQRHPFF
RHINWDDLLARRIDPPFRPCLQSEEDVSQFDTHFTRQTPVDSPDDTALSESANQAFLGFT
YVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRTPVSPLKFSPFEGFRPSSGPPEPMEPPLP
PLLPPPPPPPSSTAPLPIRPPSGTKKSKRGRGRPGR
NT seq 1551 nt   +upstreamnt  +downstreamnt
atgcgtcattggcgcgcgcggccgcggtcgcagagtgatagcgtacggcttcccccgccc
cgccccccgggctgtcagtctgagcgcggccaagcacggcaagggcccgccgggccggcg
ccgctatggcggccgtgtttgacctggacttggagacggaggaaggcagcgagggcgagc
cagagttcagcccctcggcctgtgggacactgtgaggaggtggagctgactgagaccagt
gtgaacctgggccctgaacgcatcgggccccactgctttgagctgctgcgtgtgctgggc
aaggggggctatggcaaggtgttccaagtccggaaggtgcagggcaccaacttgggcaag
atatatgccatgaaagtcctgagaaaggccaaaattgtgcgcaacgccaaggacacagca
cacacgcgggctgaacggaacattctagagtcagtgaagcaccccttcattgtggaactg
gcctatgccttccagactggtggcaaactctacctcatcctcgagtgcctcagtggcggt
gagcttttcacgcatctggagcgagagggcatcttcctggaagacacagcctgtttctac
ctggcagagatcaccctggccctgggacatctccactcccaaggcataatctaccgggac
ctcaaacctgagaacatcatgctcaacagtcagggccacatcaaactgacagactttgga
ctctgcaaagagtcgatccatgagggcgctgtcacccatactttctgtggcaccattgaa
tacatggcccctgagattctggtacgcagtggccacaaccgggctgtggactggtggagc
ctgggggccctgatgtatgacatgctcactggatcggcaagtccagcctcctggccaccc
ttcaccgcagagaaccggaagaaaaccatggacaagatcatcaaagggaaactgacgctg
cccccctacctcaccccggatgcccgggaccttgtcaaaaagtttctgaagcggaatccc
agccagcggatcgggggtggcccaggggactctgctgatgtgcagaggcaccccttcttc
cggcacattaattgggatgacctcctggctcgccgcatagacccccctttcaggccctgt
ctgcagtcagaggaggacgtgagccagtttgacacccacttcacacggcagacaccagtg
gacagtccagatgatacggccctcagtgagagtgccaaccaggccttcctgggcttcaca
tacgtggcaccttctgtcctggacagcatcaaggagggcttctcattccagcccaagcta
cgctcccccaggcgtctcaacagtagtccccggaccccggtcagccccctgaagttctca
ccctttgagggattccggcccagctctggcccaccggagcccatggagccccctctacct
cctctcctgccgccgccaccaccaccaccatcgagcactgcccctctccccatccgaccc
ccctcggggaccaagaagtctaagaggggccgtgggcgccctgggcgctag

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