KEGG   Canis lupus dingo (dingo): 112663311
Entry
112663311         CDS       T08371                                 
Symbol
DDB2
Name
(RefSeq) DNA damage-binding protein 2 isoform X2
  KO
K10140  DNA damage-binding protein 2
Organism
clud  Canis lupus dingo (dingo)
Pathway
clud03420  Nucleotide excision repair
clud04115  p53 signaling pathway
clud04120  Ubiquitin mediated proteolysis
clud05161  Hepatitis B
clud05169  Epstein-Barr virus infection
clud05200  Pathways in cancer
clud05202  Transcriptional misregulation in cancer
clud05210  Colorectal cancer
clud05212  Pancreatic cancer
clud05213  Endometrial cancer
clud05214  Glioma
clud05216  Thyroid cancer
clud05217  Basal cell carcinoma
clud05218  Melanoma
clud05220  Chronic myeloid leukemia
clud05222  Small cell lung cancer
clud05223  Non-small cell lung cancer
clud05224  Breast cancer
clud05225  Hepatocellular carcinoma
clud05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:clud00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    112663311 (DDB2)
  09124 Replication and repair
   03420 Nucleotide excision repair
    112663311 (DDB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112663311 (DDB2)
   05202 Transcriptional misregulation in cancer
    112663311 (DDB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    112663311 (DDB2)
   05212 Pancreatic cancer
    112663311 (DDB2)
   05225 Hepatocellular carcinoma
    112663311 (DDB2)
   05226 Gastric cancer
    112663311 (DDB2)
   05214 Glioma
    112663311 (DDB2)
   05216 Thyroid cancer
    112663311 (DDB2)
   05220 Chronic myeloid leukemia
    112663311 (DDB2)
   05217 Basal cell carcinoma
    112663311 (DDB2)
   05218 Melanoma
    112663311 (DDB2)
   05213 Endometrial cancer
    112663311 (DDB2)
   05224 Breast cancer
    112663311 (DDB2)
   05222 Small cell lung cancer
    112663311 (DDB2)
   05223 Non-small cell lung cancer
    112663311 (DDB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    112663311 (DDB2)
   05169 Epstein-Barr virus infection
    112663311 (DDB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:clud04121]
    112663311 (DDB2)
   03400 DNA repair and recombination proteins [BR:clud03400]
    112663311 (DDB2)
Ubiquitin system [BR:clud04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul4 complex
    Target recognizing subunit (DCAF)
     112663311 (DDB2)
DNA repair and recombination proteins [BR:clud03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     Cul4-DDB2 complex
      112663311 (DDB2)
SSDB
Motif
Pfam: WD40_CDC20-Fz WD40 WD40_Prp19 WD40_WDHD1_1st Beta-prop_EML_2 Beta-prop_WDR75_1st WDR55 Beta-prop_RIG_2nd Beta-prop_IFT140_1st Beta-prop_WDR90_POC16_2nd Beta-prop_EIPR1 EIF3I Beta-prop_WDR19_1st Beta-prop_TEP1_2nd WD40_RFWD3 Beta-prop_TEP1_C Beta-prop_CAF1B_HIR1 NBCH_WD40 WD40_MABP1-WDR62_2nd Beta-prop_HPS5 Beta-prop_Vps41 WD_LRWD1 EF-hand_1
Other DBs
NCBI-GeneID: 112663311
NCBI-ProteinID: XP_025307859
Ensembl: ENSCAFG00020022201
LinkDB
Position
18:complement(42253223..42291338)
AA seq 427 aa
MAPRKRPETQKTPEVAVRPKSKRSRSPRELEPEAKKLCVKGPGSSRRFDSGCLWAGLASL
QVPPSCSSIVRALHHHKLGKAAWPSLQQGLQQSFLHSLASYRIFQKAAPFDRRATSLAWH
PTHPSTLAVGSKGGDIMLWNFGMKDKPTFIKGIGAGGSITGLKFNPLDTNQFFTSSMEGT
TRLQDFKGNTLRVFTSSGTCNFWFCSLDVSARSRMVVTGDNVGHVILLNMDGRELWNLRM
HKKKVTHVALNPCCDWFLATASVDQTVKIWDLRQVRGKSSFLHSLPHSHPVNAACFSPDG
AQLLTTDQKSELRVYSASQWDYPPSLIPHPHRHFQHLTPIKATWHPRYNLIVVGRYPDPN
FKSCTPHELRTIDVFDGSSGKMMYQLYDPESSGIISLNEFNPMGDTLASVMGYHILIWSQ
EEARMRP
NT seq 1284 nt   +upstreamnt  +downstreamnt
atggctcccaggaaacgcccagaaacccagaagacccccgaggtggctgtgcgccccaag
agcaagaggagcagaagcccccgggagctggagcccgaggccaagaagctctgtgtgaag
ggccccggttctagcagaagatttgactcaggctgcctttgggcggggttggctagcctg
caggtcccgccatcatgcagcagcatcgtcagggcgctccaccaccataagctgggcaaa
gctgcctggccgtcactgcagcagggtctccagcagtcctttttgcattctctggcttct
taccggatattccaaaaggctgccccttttgacaggagggccacatccttggcatggcat
ccaactcaccccagcaccctggctgtgggttccaaagggggagatatcatgctctggaac
tttggcatgaaggacaaacctaccttcattaaagggattggagctggaggcagcatcact
gggctgaagtttaaccctcttgataccaaccagtttttcacctcctcaatggagggaaca
actaggctgcaagactttaaaggcaacactctgcgagtttttaccagctcaggcacctgc
aacttctggttttgcagcctggatgtgtctgccagaagccgaatggtggtcacaggagac
aatgtggggcacgtgatcctactcaacatggatggcagggagctctggaatctgagaatg
cacaaaaagaaagtgacccacgtggccctgaacccatgctgtgattggttcctggccaca
gcctccgtagaccaaacagtgaaaatctgggacctgcgccaggttagagggaaatccagc
ttcctccactcgctgccgcatagccatcctgtcaatgcagcctgtttcagtcctgatgga
gcccagctcttgaccactgaccagaagagtgagctccgggtttactcagcctcccagtgg
gactatcccccaagcctgatcccacaccctcaccgccacttccagcacctgacacccatc
aaggcaacctggcatcctcggtacaacctcattgtcgtgggccgatacccagatcccaat
ttcaaaagctgtacccctcacgaattaaggacgatcgatgtgtttgacggaagctcaggg
aagatgatgtatcagctctatgacccagaatcttctggtatcatttcgctcaatgagttc
aatcctatgggggacacactggcctctgtgatgggttatcacattctcatttggagccag
gaggaagccaggatgcggccatga

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