Canis lupus dingo (dingo): 112666222
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Entry
112666222 CDS
T08371
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
clud
Canis lupus dingo (dingo)
Pathway
clud00310
Lysine degradation
clud01100
Metabolic pathways
clud05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
clud00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
112666222 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
112666222 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
clud03036
]
112666222 (DOT1L)
Enzymes [BR:
clud01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
112666222 (DOT1L)
Chromosome and associated proteins [BR:
clud03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
112666222 (DOT1L)
HMT complexes
Dot1-containing complex
112666222 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
112666222
NCBI-ProteinID:
XP_025312593
Ensembl:
ENSCAFG00020017984
LinkDB
All DBs
Position
20:complement(57165897..57231057)
Genome browser
AA seq
1707 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVP
ENKAAVPADTPMDSGAEEEKAGATTIKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSTA
NPERKPKKSQTALDLLHAQAASQTAAPSPQDAYKSPHSPFYQLPPSVQRHPPDQLLLAPT
PPALQKLLESFKIQYLQFLAYTKTAQYKASLQQLLDQEKEKNARLLGAAQQLFGHCQAQK
EEIKRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQTEQLQKDNRELRSQSLQLL
KARCEELKLDWSTLSLENLLKEKQALRSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDEALSAHLRGKGALGRELEADPSRLHLDLDCSKFSLPHFSSASPELSMNGHAANY
ELCSALSRPSSKQNTPQYLASPLDQEVVPCTPSHSSRSRLEKMSGLALPDYTRLSPAKLV
LRRHLSQDHATSGKPAASELHPRAEHTKENGLPYQSPGIANGIKLSPQDPRPSSPVALQM
TGERGSEKGLKERAYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKVRST
PSPVPQTRESSSTLEKQMGTNTHSAGSKSLASTPAGFYTGSVAVSGALAGSPAPLAPGAE
PSAFDEVSGSGSLFASMGSCSSTPQHPPLLPQSRGSGAASPAHPLCASPRLSSVAQGPLP
DANKGDLPSEAGFSDPEGEAKRRIVFTISAGGSSAKQSPPSKPSPLPTGARGDSSQGHGS
DSRKRGRRKRASAGTPSLSSGVSPKRRALPSVAGLFTQSSGSPLNLNSMVSNINQPLEIT
AISSPESLKSSPVPYQDNDQPPILKKEKPLSQTNGAHYSPLTSDEEQGSEDEPGSARIER
KIATISLESKSPPKTLESGGGLAGRKPTPASEPTNSSKWKSTFSPISDLGLAKCADSPLQ
AGSALSQNSLFTFRPPLDDPGSADTKLAAHPRKSFPGALSGAGGLSPSSNPPNGFAFGGG
LAADLSLHSFSDGASLSHKVPEAASLGAPLSFPAPRGKEGGATEPGAFVNKRQLDGLGGP
KGREAGELGLPVCGPPDKASLTHSKPTKGRDREPDLKNGHNLFISAATVPPAGLLSGPGL
ATVASSAVSAAPSAQTHRPFLGTFAPGPQFALGPMSLQANLGSSVLQSLFSSVPAAAGLV
HVSSAATRLTNSHAMGSFSSGVAGGAVGGVFNHAVPSASAHPFGASFGSGAACRSATLSL
TPLQAVASAPASSFQAPPPPPPGQPALPAPPPPNAALPPAPALLPANSEPVLLQNLASLP
ANQAFLPASSAASLQPANASLSIKLASLPHKAPRPSFTVHHQPLPGLALAQAAPVIPQAS
STGPSAVWVSLGMPPPYAARLAGVKPR
NT seq
5124 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgaggctcaagtcgcccgtgggggccgagcccgccgtctac
ccgtggccgctgccggtctacgacaaacaccacgatgctgctcatgaaatcatcgagacc
atccgatgggtctgtgaagagatcccagacctcaagcttgctatggagaattacgtttta
atcgactacgacaccaaaagcttcgaaagcatgcagaggctctgtgacaaatacaaccgt
gccatcgacagcatccaccagctgtggaaggggaccactcagcccatgaaactgaacact
cggccgtccaacgggctcctgaggcacatcctgcagcaggtgtacaaccactcggtgacg
gaccccgagaagctcaacaactatgagcccttctccccggaggtgtacggggagacctcc
tttgacttggtcgcacagatgatcgacgagatcaagatgaccgaggatgacctgtttgtg
gacctgggcagtggagtgggccaggttgtgctgcaggtcgccgcggccaccaactgcaaa
catcactatggcgtggagaaagctgacatcccagccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaaaga
ggcgacttcctctcagaagagtggagagagcggattgccaacacaagtgttatatttgtg
aataattttgcctttggtcctgaggtggatcaccagctgaaggagcggtttgcgaacatg
aaggaaggcggcagaattgtgtcctcgaagcccttcgcacctctcaacttccggataaac
agcagaaacttgagcgacatcggcaccatcatgcgcgttgtggagctctcgcccctgaaa
ggctcggtgtcctggacggggaagccggtctcctactacctgcacactatcgaccgcacc
atacttgaaaactatttttctagtctgaaaaacccaaaactcagggaggaacaagaggca
gctcggcgccggcagcagcgagagaacaagagcaacacgaccactcccaccaaggtgccc
gagaacaaggctgctgtgcctgccgacacccctatggattctggtgccgaggaagaaaag
gctggggcaaccaccatcaaaaagccgtctccctccaaagcccggaagaagaagctgaat
aagaaggggcggaagatggccggccggaagcgtgggcgtcccaagaagatgagcactgca
aaccccgagcgtaagcccaagaagagccaaactgcactggacctcctgcatgcccaggcc
gcgtctcagacggcagcgccctcgccgcaggatgcgtacaagtcacctcatagcccgttt
tatcagctacctcccagtgtgcagcggcacccccctgaccagctgctgctggcacccacc
ccacccgcactgcagaagctgctagaatccttcaagattcagtacttgcagttcttggcg
tacaccaagaccgcccagtacaaggccagcctgcagcagctgctggaccaggagaaggag
aagaacgcccggttgctaggtgctgcgcagcagctgtttggccactgccaggcccagaaa
gaggagatcaagaggctcttccagcagaaactggatgagctgggagtgaaggcgctgacc
tacaacgacctgattcaggcacagaaggagatctcggctcataatcagcagctgagggaa
cagacggagcagctgcagaaggacaacagggagctgaggagccagagcctacagctgctc
aaggctcggtgtgaggagctaaagctggactggtccacgctgtccctggagaacctgctg
aaggagaagcaggccctgaggagccagatctccgagaagcagaggcactgcctggagctg
cagatcagcatcgtggagctggagaagagccagcggcagcaggagctcctgcagctcaag
tcctgtgtgcctccagacgaggccctgtcagcgcacctgcgtgggaagggcgccctgggc
cgggagctggaggccgaccctagccgactgcacctcgacctggactgctccaagttctct
ctgccccacttcagcagcgcaagcccagagctctccatgaacggccacgcagccaactac
gagctctgcagcgcgctgagccggccctcatccaagcagaacacgcctcagtacctggcc
tccccgctggaccaggaagtcgtaccctgcacccccagccacagcagccggtcgaggctc
gagaagatgtctggcctggccttgcccgactacaccaggctctccccggccaagctggtg
ctgcggcgtcacctgagccaggaccacgcgaccagcggcaagccagccgccagtgagctg
cacccgcgagctgagcataccaaggagaacggccttccataccagagccctggcatcgca
aacggcatcaagctgagccctcaggaccctcgaccctcgtcccccgtggccttacagatg
acaggggagaggggcagcgagaagggcttgaaggagcgtgcctatgccagcagcggagag
gccatcaccagcctgcccgttagcatcccgctcagcaccgtgcagcccagtaagctgccc
gtcagcatccctctggccagtgtggtgctgcccagccgcgccgagaaagtgagaagcacc
ccgagccctgtgccgcagacccgagagtcctcgtccacacttgaaaagcagatgggcaca
aacacccacagcgctggaagcaaaagccttgcctcaactcctgcaggcttttacacgggc
tcggtggctgtcagtggggccctggcaggcagcccagcgcccctggctcctggagcagag
cccagcgccttcgacgaggtctctggctcaggaagcctgttcgccagcatggggtcctgc
agctccaccccgcagcacccgcccctgctgccacagtcccgtggctccggtgcagcctca
cccgcccatccgctctgtgccagtccgcggctcagcagtgtcgcccagggcccgctcccc
gatgccaacaaaggggaccttccgtccgaggcgggcttctcagaccccgagggcgaagcc
aagaggaggattgtctttaccatctcagctggtggcagcagtgccaaacagtcgcctccc
agcaaacccagccctctgcccacgggtgcccgcggggacagcagccagggccatgggtcg
gacagccgcaagcggggcaggagaaagcgggcctcggcggggaccccgagcctgagctca
ggcgtatcgcctaagcgtcgggccttgccgtccgttgccggcctcttcacgcagtcttca
gggtccccactgaacctcaactctatggtcagcaacattaaccagcctttggaaatcacg
gccatctcgtcccccgagagcctgaagagctcccctgtcccttaccaggacaacgaccag
ccgcccattctcaagaaggagaagcccctgagccagaccaatggggcccactactcccca
ctgacctcagatgaggagcagggctccgaggacgagccaggcagtgccagaatcgaaaga
aaaattgcaacaatttccttagaaagcaaatcccctccaaaaaccttggaaagcggtggt
ggcctggccgggaggaagccgacccctgccagcgagcccaccaacagcagcaagtggaag
tccaccttctcgcccatctccgacctcggcctggccaagtgcgccgacagcccgctgcag
gccggctccgccctgagccagaactccctattcactttccggcctcccctcgatgatccc
ggctcggccgacaccaagctggctgcccaccccaggaaaagctttcccggcgctctgtca
ggggccggtgggctgagcccaagcagcaaccctcccaatggcttcgccttcggcgggggc
ctggccgccgacctcagtttacacagcttcagcgatggtgcttctctctcccacaaggtc
cccgaggcagccagcctgggcgcacccctgagctttcctgccccacggggcaaggagggc
ggtgccacagagcccggcgcctttgtgaacaagaggcagctggacggactgggcggcccg
aagggcagggaggcgggcgagctgggcctgccagtgtgcgggcccccggacaaggcctcg
ctgacacacagcaagcccaccaagggccgggaccgcgagcccgacctgaagaatggccac
aacctcttcatttctgctgccaccgtgcctcccgcgggcctcctcagcggccccggcctc
gccacggtggcatcctcggcagtcagcgcggccccatctgcccagactcaccgccccttc
ctgggcaccttcgcccccgggccgcagttcgccctgggtcccatgtccctgcaggccaac
ctgggctcatccgtgctgcagtccttgttcagctccgtgccggctgctgctggcctggtg
cacgtctcgtccgctgcaaccagactgaccaactcgcacgccatgggcagcttttcctcg
ggggtggcaggcggcgcagttggaggtgtctttaaccacgcggtgccttccgcctccgct
catccgtttggagccagtttcggcagcggggctgcgtgtcgcagcgccacgctgagctta
accccgctgcaggcggtggccagcgcccccgcgtcttcctttcaggccccgcccccgccc
cctccggggcagcccgccctccccgcaccccctccccctaacgccgccttgcctcctgcc
cccgcgctgctcccggctaactctgagcccgtgcttctgcagaaccttgcgtccctccca
gctaaccaggctttcttacccgcctcctctgccgcctctctgcagcctgctaacgcctct
ctgtccatcaagctcgcctccctcccgcacaaggccccccgcccctccttcacggtgcac
caccagcccctgcccgggctggccctggcccaggccgcgcccgtgatcccgcaggccagc
tccacggggccgtctgccgtgtgggtttcccttggcatgccgcctccgtatgccgcgcgc
cttgcgggggttaagccgagataa
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integrated database retrieval system
