Canis lupus dingo (dingo): 112666501
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Entry
112666501 CDS
T08371
Symbol
PDE4A
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X1
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
clud
Canis lupus dingo (dingo)
Pathway
clud00230
Purine metabolism
clud01100
Metabolic pathways
clud04024
cAMP signaling pathway
clud04928
Parathyroid hormone synthesis, secretion and action
clud05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
clud00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
112666501 (PDE4A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
112666501 (PDE4A)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
112666501 (PDE4A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
112666501 (PDE4A)
Enzymes [BR:
clud01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
112666501 (PDE4A)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
PDE4_UCR
Motif
Other DBs
NCBI-GeneID:
112666501
NCBI-ProteinID:
XP_025313283
Ensembl:
ENSCAFG00020024472
UniProt:
A0A8C0LF94
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All DBs
Position
20:complement(50964737..51011984)
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AA seq
870 aa
AA seq
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MEPPAAPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAEPERP
PHRPIERADAVDTGDRPGLRTSRMSWPSSFHGTGTGSGGASGGSCRRFEAENGPTPSPGR
SPLDSQASPGLVLHAGAAASQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTP
FAQVLASLRSVRSNFSLLTNVPIPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDW
CLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEI
PSPTMKDREKQPAPRQRPSQQPPPPGPQFQPMSQITGVKKLMHSSSLNDSSIPRFGVKTD
QEELLAQELENLNKWGLNIFCVSEYAGGRSLSCIMYTIFQERDLLKKFRIPVDTMVTYML
TLEDHYHPDVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGV
SNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDM
VLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLE
LYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL
VHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEEPRRPGHPPPPDKFQFELTLEEEEEEE
VSTAPGAFEVQGLSMAQDPSPAEDLLEADGQDMPMEVKVEEPCFTQQADSADSVAAGKDK
ARSPDASVDAVGCGGPLALSVKSPPLPALRTLPPPEEAPGLPGLPSMAAEVGAQKEQAAK
RACSACTGTSGEDPPTPPAPGGWGSAGGPT
NT seq
2613 nt
NT seq
+upstream
nt +downstream
nt
atggagcccccggccgccccctcggagaggagcctgtctctgtctctgcctgggccccgg
gagggccaggccaccctgaagccgcccccccagcacctgtggcggcagccgcggaccccc
attcgtatccagcagcgcggctactccgacagcgcggagcgcgcagagcccgagcggccg
ccacaccggcccatagagcgcgccgacgccgtggacaccggcgaccggcccggcctgcgc
acttcccgcatgtcctggccctcgtccttccacggtaccggcaccggcagcggcggcgcg
agcggaggcagctgcaggcgcttcgaggcagagaatgggcccacaccatctcctggccgc
agccccctggactcgcaggcgagcccgggcctcgtgctgcatgctggggccgctgccagc
cagcgccgggagtccttcctgtaccgttcggacagcgactacgacatgtcccccaaaacc
atgtcacggaactcgtcagtcaccagcgaggcgcacgctgaggacctcattgtgacacct
ttcgcccaggtgctggccagcctccgaagtgttcgcagcaacttctcactcctgaccaat
gtgcccattcccagcaacaaacggtccccactgggcggcccaacccctgtctgcaaggcc
acgctgtcagaagagacatgtcagcaattggcccgggagacattggaggagctggactgg
tgtctggagcagctggagaccatgcagacctaccgttccgtgagcgagatggcttctcac
aagttcaagaggatgttaaaccgtgaacttacacacctgtcagagatgagcaggtcagga
aaccaggtctctgagtacatctccaccacattcctggacaagcagaacgaagtggagatt
ccatcacccacaatgaaggatcgagaaaaacagccagccccacgtcagagaccctcccag
cagcccccgccccctgggccgcagttccagcccatgtctcagatcacaggggtgaagaaa
ctgatgcacagcagcagcctgaatgattccagcatcccccgctttggggtgaagacagat
caagaggagctcctggcccaagaactggagaacctgaacaagtggggcctgaacatcttc
tgcgtctcagaatatgctggaggccgttcactcagctgcatcatgtacacgatatttcag
gaacgggacctgctaaagaagttccgcatcccagtggacaccatggtgacttatatgctg
accctggaggaccactaccatcccgatgtggcttaccacaacagcttgcacgcggccgat
gtgctgcagtctacccatgtgctgctggcaacacccgcgctagatgctgtgttcacggac
ctggagattcttgccgccctcttcgcggctgccattcatgatgtggaccatcctggggtc
tccaaccagttcctcatcaacaccaattcggagctggcgctcatgtacaacgatgagtcg
gtgctggagaaccaccacctggccgtgggcttcaagctgctgcaggaagacaactgtgac
atcttccagaacctcagcaagcgccagcggcagagcctgcgcaagatggtcatcgacatg
gtgctggccacggacatgtccaaacacatgaccctcctggcagacctgaagaccatggtg
gagaccaagaaagtgaccagctcgggggtcctcctgctggacaactactctgaccgtatc
caggtccttcggaacatggtgcactgtgcagacctcagcaaccccaccaagccactggag
ctgtaccgccagtggactgaccgcatcatggccgagttctttcagcagggtgaccgtgaa
cgtgagcggggcatggagatcagccccatgtgcgacaagcacacagcctcggtagagaag
tctcaggtgggtttcatcgactatattgtacacccactgtgggagacgtgggctgacctg
gtccatccagatgcacaggagatcctggacacattggaggacaaccgggactggtactac
agtgccattaggcagagcccgtcaccacctccagaagaggagccaagaaggccaggccac
ccacccccacctgataagttccaatttgagctgacactggaggaggaagaggaggaggag
gtgtctactgccccaggtgcattcgaagtacagggattgtccatggctcaggatccgtcc
ccagccgaggacctgttggaggctgatggccaggatatgcccatggaggtgaaggtagag
gaaccgtgcttcacacagcaagcagactcagcagatagtgtggctgcaggcaaggacaag
gccaggtccccagatgcatccgtggatgctgtgggctgtggtggccccctggccctgtct
gtcaagagcccccctctgcctgctttgaggaccctgccccctccagaggaagccccgggc
ctcccgggcctcccctccatggcggccgaggtgggggcccaaaaagagcaggctgccaag
agggcgtgcagtgcgtgcacgggaacatctggcgaggaccccccgacccccccagctcct
ggcgggtggggatcagccggaggtcctacctga
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