Canis lupus dingo (dingo): 112671268
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Entry
112671268 CDS
T08371
Symbol
BACE1
Name
(RefSeq) beta-secretase 1 isoform X1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
clud
Canis lupus dingo (dingo)
Pathway
clud05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
clud00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
112671268 (BACE1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
clud01002
]
112671268 (BACE1)
Enzymes [BR:
clud01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
112671268 (BACE1)
Peptidases and inhibitors [BR:
clud01002
]
Aspartic peptidases
Family A1: pepsin family
112671268 (BACE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
PE-PGRS_C
Motif
Other DBs
NCBI-GeneID:
112671268
NCBI-ProteinID:
XP_025321177
Ensembl:
ENSCAFG00020001856
LinkDB
All DBs
Position
5:16308771..16332751
Genome browser
AA seq
501 aa
AA seq
DB search
MARALPWLLLWMGSGVLPARCTPPGIRLPLRSGLGAPPLGLRLPRETVEEPDEPGRRGSF
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI
DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
HVHDEFRTAAVEGPFITLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
RCLRCLRHQHDDFADDISLLK
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atggcccgagcactgccctggctcctgctgtggatgggctccggagtgctgcccgcccgc
tgcaccccgcccggcatccggctgcccctgcgcagcgggctgggggcgccccccctgggg
ctgcggctgccgcgggagaccgtcgaggagcccgacgagccgggccggaggggcagcttt
gtggagatggtggacaacctgagaggcaagtccggtcagggctactacgtggagatgacc
gtgggcagccccccgcagacgctcaacatcctggtggacacaggcagcagtaactttgca
gtgggggctgccccccaccctttcctgcatcgctactaccagaggcagctgtccagtaca
taccgggacctccgaaagggcgtgtatgtgccctacacccagggcaagtgggagggggag
ctgggcaccgacctggtgagcatcccccatggccccaacgtcactgtgcgtgccaacatc
gctgccatcaccgaatcagacaagttcttcatcaatggctccaactgggagggcatcctg
ggtctggcctatgctgagattgcaaggcccgatgactccctggagccattctttgactcc
ctggtaaagcagacccacgttcccaacctcttctccctgcagctctgtggcgctggcttc
cccctcaaccagtcagaagtgctggcctcggttggagggagcatgatcatcgggggtatc
gaccactcactgtacacgggcagcctctggtacacacccatccggcgggagtggtactac
gaggtgatcattgtaagggtggagatcaacgggcaggacctgaaaatggactgcaaggag
tacaactatgacaagagcattgtggacagtggcaccaccaaccttcgtttgcccaagaaa
gtgtttgaagctgctgtcaaatccatcaaggcagcctcttcgacggagaagttcccggat
gggttctggctgggggagcagctggtgtgctggcaggcaggcaccaccccttggaacatt
ttcccggtcatctccctctacctgatgggcgaggtcaccaatcagtccttccgcattacc
atccttcctcagcaatacctgcggccagtggaagacgtggccacatcccaagacgactgc
tacaaattcgccatttcacagtcatccacgggcaccgtaatgggagctgttatcatggag
ggcttctacgttgtctttgaccgggcccgaaaacgaattggctttgccgtcagtgcttgt
catgtgcacgatgagttcaggacggcagcagtggaaggcccgtttatcaccctggacatg
gaagactgtggctacaacattccacagacagatgagtcaaccctcatgaccatagcctac
gtcatggctgccatttgcgccctcttcatgctgccgctctgcctcatggtgtgccagtgg
cgctgcctccgctgcctgcgccatcaacatgatgactttgccgatgacatctccctgctg
aagtga
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