Canis lupus dingo (dingo): 112676379
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Entry
112676379 CDS
T08371
Symbol
POLE
Name
(RefSeq) DNA polymerase epsilon catalytic subunit A isoform X1
KO
K02324
DNA polymerase epsilon subunit 1 [EC:
2.7.7.7
]
Organism
clud
Canis lupus dingo (dingo)
Pathway
clud03030
DNA replication
clud03410
Base excision repair
clud03420
Nucleotide excision repair
Brite
KEGG Orthology (KO) [BR:
clud00001
]
09120 Genetic Information Processing
09124 Replication and repair
03030 DNA replication
112676379 (POLE)
03410 Base excision repair
112676379 (POLE)
03420 Nucleotide excision repair
112676379 (POLE)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
clud03032
]
112676379 (POLE)
03400 DNA repair and recombination proteins [BR:
clud03400
]
112676379 (POLE)
Enzymes [BR:
clud01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.7 DNA-directed DNA polymerase
112676379 (POLE)
DNA replication proteins [BR:
clud03032
]
Eukaryotic type
DNA Replication Elongation Factors
DNA polymerase epsilon complex
112676379 (POLE)
DNA repair and recombination proteins [BR:
clud03400
]
Eukaryotic type
SSBR (single strand breaks repair)
BER (base exicision repair)
Long Patch-BER factors
DNA polymerase epsilon complex
112676379 (POLE)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DUF1744
POL2_thumb
DNA_pol_B_exo1
zf_DPOE_2
DNA_pol_B
zf-DPOE
DNA_pol_B_exo2
RNase_H_2
APP_N
Motif
Other DBs
NCBI-GeneID:
112676379
NCBI-ProteinID:
XP_025329250
LinkDB
All DBs
Position
26:563698..617227
Genome browser
AA seq
2298 aa
AA seq
DB search
MVWRNSGRRRAEPGPDGEASRDDGLSSSVSALKRLERSQWTDKMDLRFGFERLKESGEKT
GWLINMHPTEILDEDKRLVSAVDYYFIQDDGSRFKVALPYEPYFYIAARKGCEREVSSFL
SKKFQGRIAKIETVPKEDLDLPNHLVGLKRNYIKLSFHTVEDLVRVRKDVSPAVKKNREQ
GHAGDAYTAMLSSVLQGGSVVIDEEEASKKVTDQLDNIVDMREYDVPYHIRLSIDLKIHV
AHWYNIRYRGSAFPVEITRRDDLVERPDPVVLAFDIETTKLPLKFPDAETDQIMMISYMI
DGQGYLITNREIVSEDVEDFEFTPKPEYEGPFCVFNEPDEVHLIQRWFEHVQEMKPTIMV
TYNGDFFDWPFVEARAAVHGLSMYQEIGFQKDSQGEYKASQCIHMDCLRWVKRDSYLPVG
SHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLATYSVSDAVATYYLYMKYVHPFIFA
LCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQEFNKLTGDGHVLDAETYV
GGHVEALESGVFRSDIPCRFRMNPAAFDFLLQRVEKTMRHAIEEEEKVPMEHVTNFQEVC
DQIKTKLTSLKDVPNRIECPLIYHLDVGAMYPNIILTNRLQPSAVVDEATCAACDFNKPG
ANCQRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPPLTAEGPARAFHELSREEQAKYEK
RRLSDYCRKAYKKIHVTRVEERLTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLS
AAMEVGDAAEVKRCKNMEVLYDSLQLAHKCILNSFYGYVMRRGARWYSMEMAGIVCFTGA
NIITQARELIEQIGRPLELDTDGIWCVLPNSFPENFVIKTTSVKKPKVTISYPGAMLNIM
VKEGFTNDQYQELTEPSSLTYVTRSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFN
EDGSLAELKGFEIKRRGELQLIKIFQSSVFEAFLKGSTLEEVYGSVAKVADYWLDVLYSK
AANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYII
SRKPEGSPVTERAIPLAIFQAEPMVRKHFLRKWLKSSSLQDFDIRTILDWEYYIERLGSA
IQKIITIPAALQQVKNPVPRVKHPDWLHKKLLEKNDVCKQKKISELFVLEGRRQVGMAQV
PEGTQSLGAPDMEDFGLMKPLHLAVPIATKRKRVLWESQEESHDLELTVPWQEILGQPPA
LGTTQEEWLVWLRFHKKKWQLQARQRLACKKRRCVEVAEGEPLPGAIRERPATGLGGFLR
RTARSILDLPWQIVQISETSQAGLFRLWAVISSDLYCIRLNIPRVFYVNQQVAKAEEGPS
YRKVSRVLPRSNMVYNLYEYSVPEDMYQEHINEINTELSAPDIEGVYETQVPLLFRALVQ
LGCVCVVNKQLVRHLSGWEAETFALEHLEMRSLAQFSYLEPGSIRHLYLYHHAQGHKALF
GLFVPSQRRASVFVLDTVRSNQMPSLSALYSAEHSLLMEKVGPELLPPPKHTFEVRAETD
MKTICRAIQRFLLAYKEERRGPTLIAVQSNWELKRLAGEVPVLEEFPLVPVHVADKISYG
VLDWQRLGARRMIRHYLNLDTSLSQAFEMSRYFHIPIGNLPEDISTFGSDLFFARHLQRH
SHLLWLSPTSRPDLGGKEADDNRLVMEFDDQASVEINCPGCYSTVCVELDIQNLAVNTIL
QSHHINDMEGADSMGISFDVIQQASLEDMITGNQAANTPASYDETALCSSTFRILKSMVV
GWVKEITQYRNIYADNQVMHFYRWLRSPSSLLHDPVLHRTLHNMMKKLFLQLIAEFKRLG
SSVVYANFNRIILCTKKRRIEDAIAYMEYITSSIHSKEIFHSLTISFSRCWEFLLWMDPS
NYGGIKGNAPSSIHYGQQDSQKGGRVEEEEEEEEEEEEGKQEPDVEDMLENNWNIVQFLP
QAASCQSYFLMIVSAYIVAVYHSMKEELRRSAPGGTPLRWRGPSQLSQDAAASSALPAMV
PALLGMITFSQDYVANELTQNFFTITQKIQKKVTGSRSSTELSSMFPALPGSHLLLNNPA
LEFIKYVCKVLSLDTNITNQVNKLNRDLLRLVDVGEFSEEAQFRDPCRSYVLPEVICRSC
NFCRDLDLCKEFAFSQDGAVLPQWLCSNCQVAYDTSVIEMALVEALQKKLMAFTLQDLAG
ETPDQDCSSLQICLKCRGVKETNMPVYCSCAGGFTLTIHTKVFMEQIGIFQNIAQHYGMS
YLTETLEWLLQKNPQLGH
NT seq
6897 nt
NT seq
+upstream
nt +downstream
nt
atggtttggaggaacagcggccggcgtcgcgcggagccgggcccggacggcgaggccagc
cgggatgatggcctctcctcttctgtctcagcacttaagcgcctggagcgcagtcagtgg
acagataagatggatttgcggtttggttttgagagactcaaggagtctggggagaagacg
ggctggcttatcaacatgcaccctactgagattttagatgaagacaaacgcttagtcagc
gcagtagattactactttattcaagatgatgggagcagatttaaggtggccttgccctac
gagccgtatttctacattgcagccagaaagggttgtgaacgagaagtttcatcttttctc
tccaagaagtttcagggtagaattgctaaaatagagactgtccccaaagaggatctagac
ttgccaaatcacttggtgggtttgaagcgaaattacattaagctgtccttccacactgtg
gaggatcttgttagagtgaggaaggatgtctcccctgctgtgaagaagaaccgggagcag
ggtcatgctggtgatgcctacacagctatgctgtccagcgttctgcaagggggcagtgtg
gttattgatgaagaggaagcctctaagaaggtcactgaccagttggacaatattgtggac
atgcgagagtatgatgtgccctaccacatccgcctctccattgacctgaagatccatgtg
gctcattggtacaacatcagataccgaggaagtgcctttcctgtggaaatcacccgccga
gatgaccttgttgaacgacctgaccctgtggttttggcatttgacattgagacaaccaaa
ctgcctctcaagtttcctgatgctgagactgaccagattatgatgatttcctacatgatt
gatggtcagggctacctcatcaccaacagggagatcgtttcagaagatgtcgaagatttc
gagttcacccccaagccagagtatgaaggacctttttgtgtctttaatgaacctgacgag
gttcatctaatccagagatggtttgaacatgtccaggagatgaaacccaccatcatggtc
acctacaatggggacttttttgactggccgtttgtggaggccagagcagcagtccacgga
ctaagcatgtaccaggagatcgggttccagaaggacagtcagggagagtacaaggcatcc
cagtgcatccacatggactgtctcaggtgggtgaagagggacagttaccttcctgtgggc
agccacaacctcaaggcagctgccaaagccaagctaggctatgacccagtggagctggac
cctgaggacatgtgccgaatggccaccgagcagccccagactctggccacgtactccgtg
tcagatgcagtggccacgtactacctgtacatgaaatacgtccacccctttatattcgcc
ctttgcaccattatccccatggagcctgatgaggtgctgcggaagggctctgggactctc
tgtgaggccttgctgatggtgcaggccttccacgccaacatcatcttccccaataagcag
gagcaggagttcaacaagctgacaggtgatggccacgtgctggatgccgagacctatgtg
ggtggccacgtggaggcccttgagtcaggcgtctttcgcagtgacatcccctgccggttc
aggatgaatcctgctgcctttgacttcctgctgcagagggtggagaagaccatgcgccat
gccatcgaggaagaggagaaggtgcccatggagcatgtcaccaacttccaagaggtgtgt
gatcagattaagaccaagctcacctccctgaaagatgttccaaacagaatagagtgtccc
cttatctaccacctggatgtgggggccatgtaccctaacatcatcctgacgaaccgcctg
cagccctctgccgtggtggatgaggctacctgtgctgcctgtgacttcaataagcctggg
gccaactgccagagaaagatggcctggcagtggaggggcgagttcatgccagccagtcgc
agtgagtaccatcggatccagcaccagctggagtcagagaagttccctcccttgactgca
gagggtccagcccgggcctttcacgagctctctcgagaggagcaggctaaatatgagaag
cggaggctgtcagattactgccggaaggcatacaagaagatacacgtcaccagggtggag
gagcgcctcaccactatctgccagcgggagaactctttctatgtggacacagtgcgcgcc
ttccgagacaggcgttatgaattcaaaggtctccacaaggtgtggaagaagaaactctct
gcagccatggaggtgggtgatgcggccgaagtgaagcgctgcaagaacatggaggtcctg
tatgactccctgcagctggcgcacaagtgcatcctcaactccttctatggctacgtcatg
cgcagaggggctcgctggtactccatggagatggcaggcattgtctgcttcacaggggct
aacatcatcacccaggcacgggagctgattgagcagatcgggagacccttggagctggac
acagacggaatatggtgcgtcctgcccaacagctttcctgaaaactttgtcatcaagaca
accagtgtgaaaaagcccaaggtgaccatttcctaccctggggccatgttgaacatcatg
gtgaaggaaggcttcaccaatgatcagtaccaggagctgactgaaccatcctcactcacc
tatgtcacccgttcagagaacagcatctttttcgaggttgacggaccctaccttgccatg
atccttccagcctccaaggaagaaggcaagaaactgaagaagagatatgctgtcttcaac
gaggacggttccctggctgagctgaagggcttcgagatcaaacgccgaggggagctgcag
ctgattaagatcttccagtcctcagtgttcgaggctttcctcaagggcagcaccttagaa
gaagtgtatggctctgttgccaaggtggctgactactggctggacgtgctgtacagtaag
gcagctaacatgcccgattctgagctgtttgagctgatctctgagaatcgctccatgtct
cggaagctggaagattatggggagcagaagtccacgtctatcagcacagccaagcgcctg
gctgagttcctgggagatcagatggtgaaggatgcagggctgagctgccgttacatcatc
tctcggaagcccgagggctctccggtcacagagagggccatcccgcttgccattttccag
gcagagcccatggtgaggaagcactttctccggaaatggcttaagagttcttccctccaa
gactttgatattcgcacgattttggattgggagtactacattgagcggctagggagtgcc
atacagaagatcatcacgatccctgcagctttgcagcaggtaaagaacccagtaccacgc
gtcaagcaccctgactggctgcacaagaaacttttggagaagaatgatgtctgcaagcag
aagaagatcagcgagctctttgtcctcgagggcaggagacaggtgggcatggcccaggtt
ccagaaggcacccaaagcctgggtgctcctgatatggaagattttggcctcatgaagcca
ttgcacttggccgttcctattgccactaagaggaagcgtgtcctctgggagagccaggag
gagtcacacgacctggagctgacggtgccctggcaggaaatcttggggcagcctccagcc
cttggaaccacccaggaagagtggctggtttggctccggttccataagaagaagtggcag
ctgcaggcccggcagcgcctggcttgcaagaagaggcggtgtgtggaggtggcagagggc
gaacctctgcctggggccatccgagaaaggcctgccactgggttggggggcttcctgcga
aggaccgcccgcagcatcttggaccttccatggcagattgtgcagatcagtgaaaccagc
caggctggtttattcaggctgtgggctgtcatcagcagtgacttgtactgcatcaggctg
aacatcccccgagtattctatgtcaaccagcaggtggctaaagctgaggaggggccttcc
tatcgcaaggtcagccgagtccttcctcgctccaacatggtctacaatctctatgagtac
tccgtgcctgaggacatgtaccaggaacatatcaatgaaatcaatactgagttatcagcc
ccagacattgagggcgtgtatgagactcaggttccattactattccgcgccctagtgcag
ctgggctgtgtctgtgtggtcaataaacagctggtgaggcacctttcaggctgggaagca
gaaacctttgctctcgagcacctggagatgcgttctctggctcagttcagctacctggaa
ccagggagcatccgccacctctacctgtaccatcatgcacagggccacaaagcactcttc
ggcttgttcgtgccctcccagcgcagagcatctgtgtttgtgttggacactgtgcgaagc
aaccagatgcccagcctcagcgctctttactcagccgagcacagccttctgatggagaaa
gtgggcccggagctcctgcctcctcccaaacacacttttgaagttcgggcggaaactgac
atgaaaaccatctgcagagccatccagcgcttcctgctggcctacaaagaggagcgccgt
gggcccacactcatcgctgttcagtccaactgggagctaaagaggctggctggtgaggtt
cctgtcctagaggaattcccactagtgcctgtccacgtggcagataagatcagctatgga
gtcctggactggcagcgcctcggagcccggcgcatgatccgccactacctcaacctggac
acctctctgtcacaggccttcgagatgagcaggtacttccacatccccattggtaatctg
cctgaggacatctccacctttggctccgacctcttctttgcccgccatctccagcgccac
agccacctgctctggctgtcgcctacgtcacgccctgacctgggtggcaaggaggctgat
gacaatcgccttgtcatggaattcgatgaccaggccagcgtggagatcaattgtccaggc
tgctactctacagtgtgtgtggagctggacatccaaaacctggctgtcaacaccatcctg
cagtcccaccatatcaatgacatggagggggctgacagcatgggcatcagctttgatgtg
atccagcaagcctctctggaggacatgatcactggcaaccaggccgccaacactccagcc
agctacgatgagacagccctctgctccagcaccttcaggatcctgaagagcatggtggtg
ggctgggtgaaggagatcacacagtaccgcaacatctatgctgacaaccaggtgatgcac
ttttaccgctggctccggtccccatcatcactgctccatgaccctgtgctgcatcgcaca
ctccacaacatgatgaagaagctctttctgcagctcatcgctgagttcaagcgcttgggg
tcatctgtcgtctatgccaacttcaaccgcatcatcctctgcacgaaaaagcggcggatc
gaggatgccattgcttacatggagtacatcaccagcagcatccattctaaagagatcttc
cattctttgacaatatctttctctcggtgctgggaatttcttctctggatggatccctct
aactatggtggaatcaaaggaaatgctccatctagtatccactatggacagcaagactcc
caaaaagggggcagagtagaggaggaggaggaggaggaggaagaggaggaggaaggcaaa
caggaaccagatgtggaggacatgctggaaaacaactggaacattgtgcagttcctgcca
caggcagcctcctgccagagctacttcctcatgattgtttcagcatacatcgtggccgtg
taccacagcatgaaggaggagctgcggcgcagtgccccagggggcacacccctgagatgg
cgggggcccagccagctctcccaggatgctgcggcctccagtgcccttcctgctatggtc
cctgccctcctaggaatgatcaccttctcccaagactacgtggccaacgagctgactcag
aacttcttcaccatcactcagaagattcagaagaaagtcacaggctcccggagctccact
gagctctccagcatgtttcctgcccttccaggttctcacttgctgctcaacaaccccgca
ttggagttcatcaagtacgtgtgcaaggttctgtctctggacacgaacatcacaaaccag
gtgaacaaattgaaccgggatctgcttcgtctggtggatgttggcgagttctcggaggag
gcacagttccgagacccttgccgttcctacgtgctccctgaggtcatctgccgcagctgt
aacttctgccgggacctggacctgtgtaaagagttcgccttctcgcaggatggggccgtg
ctgcctcagtggctctgctcaaactgtcaggttgcctatgacacctcagtcatcgagatg
gccctggtggaagccctgcagaagaaactgatggccttcactctgcaggacctggctggg
gagactcctgaccaggactgctcctcattgcagatctgcctgaagtgccgaggtgtgaag
gagaccaacatgcctgtgtactgcagctgcgccgggggctttaccctcaccatccacacc
aaggtcttcatggagcagattggaatcttccagaacattgcccagcactatggcatgtcc
tacctcacagagaccctggagtggctgctgcagaagaaccctcagctgggccactag
DBGET
integrated database retrieval system
