KEGG   Canis lupus dingo (dingo): 112677029
Entry
112677029         CDS       T08371                                 
Symbol
MAPK1
Name
(RefSeq) mitogen-activated protein kinase 1
  KO
K04371  mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
Organism
clud  Canis lupus dingo (dingo)
Pathway
clud01521  EGFR tyrosine kinase inhibitor resistance
clud01522  Endocrine resistance
clud01524  Platinum drug resistance
clud04010  MAPK signaling pathway
clud04012  ErbB signaling pathway
clud04014  Ras signaling pathway
clud04015  Rap1 signaling pathway
clud04022  cGMP-PKG signaling pathway
clud04024  cAMP signaling pathway
clud04062  Chemokine signaling pathway
clud04066  HIF-1 signaling pathway
clud04068  FoxO signaling pathway
clud04071  Sphingolipid signaling pathway
clud04072  Phospholipase D signaling pathway
clud04114  Oocyte meiosis
clud04140  Autophagy - animal
clud04148  Efferocytosis
clud04150  mTOR signaling pathway
clud04151  PI3K-Akt signaling pathway
clud04210  Apoptosis
clud04218  Cellular senescence
clud04261  Adrenergic signaling in cardiomyocytes
clud04270  Vascular smooth muscle contraction
clud04350  TGF-beta signaling pathway
clud04360  Axon guidance
clud04370  VEGF signaling pathway
clud04371  Apelin signaling pathway
clud04380  Osteoclast differentiation
clud04510  Focal adhesion
clud04517  IgSF CAM signaling
clud04520  Adherens junction
clud04540  Gap junction
clud04550  Signaling pathways regulating pluripotency of stem cells
clud04611  Platelet activation
clud04613  Neutrophil extracellular trap formation
clud04620  Toll-like receptor signaling pathway
clud04621  NOD-like receptor signaling pathway
clud04625  C-type lectin receptor signaling pathway
clud04650  Natural killer cell mediated cytotoxicity
clud04657  IL-17 signaling pathway
clud04658  Th1 and Th2 cell differentiation
clud04659  Th17 cell differentiation
clud04660  T cell receptor signaling pathway
clud04662  B cell receptor signaling pathway
clud04664  Fc epsilon RI signaling pathway
clud04666  Fc gamma R-mediated phagocytosis
clud04668  TNF signaling pathway
clud04713  Circadian entrainment
clud04720  Long-term potentiation
clud04722  Neurotrophin signaling pathway
clud04723  Retrograde endocannabinoid signaling
clud04724  Glutamatergic synapse
clud04725  Cholinergic synapse
clud04726  Serotonergic synapse
clud04730  Long-term depression
clud04810  Regulation of actin cytoskeleton
clud04910  Insulin signaling pathway
clud04912  GnRH signaling pathway
clud04914  Progesterone-mediated oocyte maturation
clud04915  Estrogen signaling pathway
clud04916  Melanogenesis
clud04917  Prolactin signaling pathway
clud04919  Thyroid hormone signaling pathway
clud04921  Oxytocin signaling pathway
clud04926  Relaxin signaling pathway
clud04928  Parathyroid hormone synthesis, secretion and action
clud04929  GnRH secretion
clud04930  Type II diabetes mellitus
clud04933  AGE-RAGE signaling pathway in diabetic complications
clud04934  Cushing syndrome
clud04935  Growth hormone synthesis, secretion and action
clud04960  Aldosterone-regulated sodium reabsorption
clud05010  Alzheimer disease
clud05020  Prion disease
clud05022  Pathways of neurodegeneration - multiple diseases
clud05034  Alcoholism
clud05132  Salmonella infection
clud05133  Pertussis
clud05135  Yersinia infection
clud05140  Leishmaniasis
clud05142  Chagas disease
clud05145  Toxoplasmosis
clud05152  Tuberculosis
clud05160  Hepatitis C
clud05161  Hepatitis B
clud05163  Human cytomegalovirus infection
clud05164  Influenza A
clud05165  Human papillomavirus infection
clud05166  Human T-cell leukemia virus 1 infection
clud05167  Kaposi sarcoma-associated herpesvirus infection
clud05170  Human immunodeficiency virus 1 infection
clud05171  Coronavirus disease - COVID-19
clud05200  Pathways in cancer
clud05203  Viral carcinogenesis
clud05205  Proteoglycans in cancer
clud05206  MicroRNAs in cancer
clud05207  Chemical carcinogenesis - receptor activation
clud05208  Chemical carcinogenesis - reactive oxygen species
clud05210  Colorectal cancer
clud05211  Renal cell carcinoma
clud05212  Pancreatic cancer
clud05213  Endometrial cancer
clud05214  Glioma
clud05215  Prostate cancer
clud05216  Thyroid cancer
clud05218  Melanoma
clud05219  Bladder cancer
clud05220  Chronic myeloid leukemia
clud05221  Acute myeloid leukemia
clud05223  Non-small cell lung cancer
clud05224  Breast cancer
clud05225  Hepatocellular carcinoma
clud05226  Gastric cancer
clud05230  Central carbon metabolism in cancer
clud05231  Choline metabolism in cancer
clud05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
clud05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:clud00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    112677029 (MAPK1)
   04012 ErbB signaling pathway
    112677029 (MAPK1)
   04014 Ras signaling pathway
    112677029 (MAPK1)
   04015 Rap1 signaling pathway
    112677029 (MAPK1)
   04350 TGF-beta signaling pathway
    112677029 (MAPK1)
   04370 VEGF signaling pathway
    112677029 (MAPK1)
   04371 Apelin signaling pathway
    112677029 (MAPK1)
   04668 TNF signaling pathway
    112677029 (MAPK1)
   04066 HIF-1 signaling pathway
    112677029 (MAPK1)
   04068 FoxO signaling pathway
    112677029 (MAPK1)
   04072 Phospholipase D signaling pathway
    112677029 (MAPK1)
   04071 Sphingolipid signaling pathway
    112677029 (MAPK1)
   04024 cAMP signaling pathway
    112677029 (MAPK1)
   04022 cGMP-PKG signaling pathway
    112677029 (MAPK1)
   04151 PI3K-Akt signaling pathway
    112677029 (MAPK1)
   04150 mTOR signaling pathway
    112677029 (MAPK1)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    112677029 (MAPK1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    112677029 (MAPK1)
   04148 Efferocytosis
    112677029 (MAPK1)
  09143 Cell growth and death
   04114 Oocyte meiosis
    112677029 (MAPK1)
   04210 Apoptosis
    112677029 (MAPK1)
   04218 Cellular senescence
    112677029 (MAPK1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    112677029 (MAPK1)
   04520 Adherens junction
    112677029 (MAPK1)
   04540 Gap junction
    112677029 (MAPK1)
   04550 Signaling pathways regulating pluripotency of stem cells
    112677029 (MAPK1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    112677029 (MAPK1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    112677029 (MAPK1)
   04613 Neutrophil extracellular trap formation
    112677029 (MAPK1)
   04620 Toll-like receptor signaling pathway
    112677029 (MAPK1)
   04621 NOD-like receptor signaling pathway
    112677029 (MAPK1)
   04625 C-type lectin receptor signaling pathway
    112677029 (MAPK1)
   04650 Natural killer cell mediated cytotoxicity
    112677029 (MAPK1)
   04660 T cell receptor signaling pathway
    112677029 (MAPK1)
   04658 Th1 and Th2 cell differentiation
    112677029 (MAPK1)
   04659 Th17 cell differentiation
    112677029 (MAPK1)
   04657 IL-17 signaling pathway
    112677029 (MAPK1)
   04662 B cell receptor signaling pathway
    112677029 (MAPK1)
   04664 Fc epsilon RI signaling pathway
    112677029 (MAPK1)
   04666 Fc gamma R-mediated phagocytosis
    112677029 (MAPK1)
   04062 Chemokine signaling pathway
    112677029 (MAPK1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    112677029 (MAPK1)
   04929 GnRH secretion
    112677029 (MAPK1)
   04912 GnRH signaling pathway
    112677029 (MAPK1)
   04915 Estrogen signaling pathway
    112677029 (MAPK1)
   04914 Progesterone-mediated oocyte maturation
    112677029 (MAPK1)
   04917 Prolactin signaling pathway
    112677029 (MAPK1)
   04921 Oxytocin signaling pathway
    112677029 (MAPK1)
   04926 Relaxin signaling pathway
    112677029 (MAPK1)
   04935 Growth hormone synthesis, secretion and action
    112677029 (MAPK1)
   04919 Thyroid hormone signaling pathway
    112677029 (MAPK1)
   04928 Parathyroid hormone synthesis, secretion and action
    112677029 (MAPK1)
   04916 Melanogenesis
    112677029 (MAPK1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    112677029 (MAPK1)
   04270 Vascular smooth muscle contraction
    112677029 (MAPK1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    112677029 (MAPK1)
  09156 Nervous system
   04724 Glutamatergic synapse
    112677029 (MAPK1)
   04725 Cholinergic synapse
    112677029 (MAPK1)
   04726 Serotonergic synapse
    112677029 (MAPK1)
   04720 Long-term potentiation
    112677029 (MAPK1)
   04730 Long-term depression
    112677029 (MAPK1)
   04723 Retrograde endocannabinoid signaling
    112677029 (MAPK1)
   04722 Neurotrophin signaling pathway
    112677029 (MAPK1)
  09158 Development and regeneration
   04360 Axon guidance
    112677029 (MAPK1)
   04380 Osteoclast differentiation
    112677029 (MAPK1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    112677029 (MAPK1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112677029 (MAPK1)
   05206 MicroRNAs in cancer
    112677029 (MAPK1)
   05205 Proteoglycans in cancer
    112677029 (MAPK1)
   05207 Chemical carcinogenesis - receptor activation
    112677029 (MAPK1)
   05208 Chemical carcinogenesis - reactive oxygen species
    112677029 (MAPK1)
   05203 Viral carcinogenesis
    112677029 (MAPK1)
   05230 Central carbon metabolism in cancer
    112677029 (MAPK1)
   05231 Choline metabolism in cancer
    112677029 (MAPK1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    112677029 (MAPK1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    112677029 (MAPK1)
   05212 Pancreatic cancer
    112677029 (MAPK1)
   05225 Hepatocellular carcinoma
    112677029 (MAPK1)
   05226 Gastric cancer
    112677029 (MAPK1)
   05214 Glioma
    112677029 (MAPK1)
   05216 Thyroid cancer
    112677029 (MAPK1)
   05221 Acute myeloid leukemia
    112677029 (MAPK1)
   05220 Chronic myeloid leukemia
    112677029 (MAPK1)
   05218 Melanoma
    112677029 (MAPK1)
   05211 Renal cell carcinoma
    112677029 (MAPK1)
   05219 Bladder cancer
    112677029 (MAPK1)
   05215 Prostate cancer
    112677029 (MAPK1)
   05213 Endometrial cancer
    112677029 (MAPK1)
   05224 Breast cancer
    112677029 (MAPK1)
   05223 Non-small cell lung cancer
    112677029 (MAPK1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    112677029 (MAPK1)
   05170 Human immunodeficiency virus 1 infection
    112677029 (MAPK1)
   05161 Hepatitis B
    112677029 (MAPK1)
   05160 Hepatitis C
    112677029 (MAPK1)
   05171 Coronavirus disease - COVID-19
    112677029 (MAPK1)
   05164 Influenza A
    112677029 (MAPK1)
   05163 Human cytomegalovirus infection
    112677029 (MAPK1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    112677029 (MAPK1)
   05165 Human papillomavirus infection
    112677029 (MAPK1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    112677029 (MAPK1)
   05135 Yersinia infection
    112677029 (MAPK1)
   05133 Pertussis
    112677029 (MAPK1)
   05152 Tuberculosis
    112677029 (MAPK1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    112677029 (MAPK1)
   05140 Leishmaniasis
    112677029 (MAPK1)
   05142 Chagas disease
    112677029 (MAPK1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    112677029 (MAPK1)
   05020 Prion disease
    112677029 (MAPK1)
   05022 Pathways of neurodegeneration - multiple diseases
    112677029 (MAPK1)
  09165 Substance dependence
   05034 Alcoholism
    112677029 (MAPK1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    112677029 (MAPK1)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    112677029 (MAPK1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    112677029 (MAPK1)
   04934 Cushing syndrome
    112677029 (MAPK1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    112677029 (MAPK1)
   01524 Platinum drug resistance
    112677029 (MAPK1)
   01522 Endocrine resistance
    112677029 (MAPK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:clud01001]
    112677029 (MAPK1)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:clud03036]
    112677029 (MAPK1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:clud04147]
    112677029 (MAPK1)
Enzymes [BR:clud01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     112677029 (MAPK1)
Protein kinases [BR:clud01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   112677029 (MAPK1)
Chromosome and associated proteins [BR:clud03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Protein kinases
     112677029 (MAPK1)
Exosome [BR:clud04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   112677029 (MAPK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH STATB_N Haspin_kinase FTA2 Kdo
Other DBs
NCBI-GeneID: 112677029
NCBI-ProteinID: XP_025330731
Ensembl: ENSCAFG00020015099
LinkDB
Position
26:complement(30270619..30389523)
AA seq 360 aa
MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFE
HQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQH
LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDH
TGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI
LGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHK
RIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
NT seq 1083 nt   +upstreamnt  +downstreamnt
atggcggcggcggcggcggcgggcgcgggcccggagatggtccgcgggcaggtgttcgac
gtggggccgcgctacaccaacctctcctacatcggcgagggcgcctacggcatggtgtgc
tctgcttatgataatgtcaacaaagttcgagtagccatcaagaaaatcagtccttttgag
caccagacctactgccagagaaccctgagggagataaaaatcttactgcgcttcagacat
gagaacatcattggaatcaatgatattattcgagcaccaaccatcgagcaaatgaaagat
gtatatatagtacaagacctcatggaaacagatctttacaagctcttgaagacgcaacac
ctcagcaacgaccatatctgctattttctttaccagatcctcagagggttaaaatatatc
cattcagctaatgtactgcaccgtgacctcaaaccttccaacctgctgctcaataccacc
tgcgatctcaagatctgtgactttggcttggcccgtgttgcagatccggatcatgatcac
acagggttcctgacggagtatgtagccacacgttggtacagggctccagaaattatgttg
aattccaagggctataccaagtccattgatatttggtctgtaggctgcattctggcagag
atgctgtccaacaggcccatcttcccggggaagcattatctcgaccagctgaaccacatt
ttgggtattcttggatccccatcacaggaagacctgaactgtataataaatttaaaagct
agaaactacttgctttctcttccacacaaaaataaggtgccatggaacaggctgttccca
aatgctgactcgaaagctctggatttactggacaaaatgttgacattcaaccctcacaag
aggattgaagtagaacaggctctggcccatccgtatctggagcagtattatgacccaagt
gatgagcccatcgctgaggcgccattcaagtttgacatggagctagatgacctgcccaag
gaaaagctcaaggagctcatcttcgaagagacagctagattccagccgggatacagatct
taa

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