Canis lupus dingo (dingo): 112677359
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Entry
112677359 CDS
T08371
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
clud
Canis lupus dingo (dingo)
Pathway
clud05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
clud00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
112677359 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
clud03021
]
112677359 (SETX)
Enzymes [BR:
clud01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
112677359 (SETX)
5.6.2.5 RNA 5'-3' helicase
112677359 (SETX)
Transcription machinery [BR:
clud03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
112677359 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
AAA_22
nSTAND3
ResIII
SLFN-g3_helicase
NAT10_TcmA_helicase
AAA_16
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
112677359
NCBI-ProteinID:
XP_025331361
Ensembl:
ENSCAFG00020024489
LinkDB
All DBs
Position
9:53175026..53255962
Genome browser
AA seq
2699 aa
AA seq
DB search
MLQKRCRMSTCCWCTPGGISTVDFLQRYASKIYSSEFQTADEDLCYCLECVTEYHKARDE
LPFLHEVLWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEAQLFDFTGQDFENKLRVP
LLEILKYPYLLLHERVSELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAIL
TARNLGKVDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTN
YKNYWLGICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERQADDDSVDPFWPALHCF
MVILDRLGSKVWGQRIDPIEAFQTIINNVSYNREIQNIRNSSVRTKLEPESYSDDMVTCS
QIVYNYNPEKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIP
FVQSLMDLKDLGMAYIVEVIHHLHSEVKDVLNQTDAICDKVTEFFLLILVSVIELHRNKK
CLHLLWISSQQWVEAVVKCAKLPTTAFTRNSEKSSGNCSKGTAMISSLSLHSMPSNSVQL
ACVQLIRSLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTTQETHELQACLKQIIK
NIKVKVPQCSNFVDLSPTCKSSPVSYNKEESEQIERKSKKDLFCLENSSPTFPKESIKAE
MYQMQENILIKASNTVEEDNEQNYIKDLKLEDLSAESCIKQSSKSLFTERAQDQVKISTE
KPKSVKENCTSRSVLQNFTSRNGPERACDRGIITHLLTDSSTDSLEKMSTSNEDFSFKDD
VLGKTSKTKIKSQKDEICAKLSHVIKKQHRKSTFIDDIGNLEENLTVSNVDNFYSRKESG
DQKGDSFMHSLSLDPNGILDDKNGEQKSHKSLLLKKKQLKSEEFDIFSYHENSYQIQECH
TDDKDLVSFTEMTNTFVKKTSPFKDPVTVTVLESRDKEISKSTSPVSSHLRERIPGLSPQ
SDTLTDSQIDRDLHKLSLIAQASVIKFPSDSTQKSSSQLRRKVKDRCFLADQNNTGEACW
GQVIIISDSDDDDDDEEEEEEGILGFEKPIKQDKIGIKKEYLKQHTSIASTNVEKKLMKE
EETLLQFEESDSQFFEFESPCEVFSVWQDQEPDKNSVQEGEKNSRSTDIADLMNDWGYET
DYVSEEVIKKVAEGIEKHTEPQSSSVGEFCKIEVKKRKRKRFEKPVAEDPVRPSSSERNE
DQPDILNGRGLTENDLKNRDLRMASPSSSARRDKNTTVSLKKSSPKLRTYSKPIRRVPLS
KTPKKTHSDTKKGQSKNSNYISCRTTPAVVPPKKFRQCPEPTSTVEKLGLKKAPRRAFEL
SQRSLDYLVQLRDHGKTVGVVDTRKKTKLISPQTLSVRNNKKLLTSQDLQFRRQMRPKSQ
QNKKGLLDYESKETTRAGPRPAQNSDILVPESDSSDYSSKGGTEVVANNTGKQLIKCVSS
EPEPIKTKCASRVTDDTCLLNQCASVVLNGRIPTNEVIVSPSADPLAGGDPTIHHLELAT
LKEGEPEYNSDTEDENIFLTQHHPEDMDLCSQMENGNEKLIEIVHRRDTAQVEEDSVGQP
QLASWSSTKCKYKDCVETPENQGEYCSKHCEAKAADEDVFRKPALPLSASKPSRPSTAKI
FSSSSTSRIAGLSKSLESSSGLPPALKNKSNGGQAILKAPQPVSLLSPKAVGEVKSLCNV
LHPQTPNNSNRQGYKLTFGENKSFSASSPVNILLSSQSISDTFVKEILKWKYEMFVNFDQ
CGPPASLCQSISRPVPVRFQDCGDYFNVFFPLMILNTFETVAQEWISSPNKEKFYQLHLR
KFPADYKKYWEFVVHLEECELAKQLHPKENDLVFLISERQNGEKKDTERNRMQDLREYHC
GYVHKFRRTSVMRNGKSECFLYIQTQDNLPVNLNEFVKCVVISSLVTTQRKLKAMSLLSG
RNQLARAVLNPNPMDFCTKDLLTTTSERIVAYLRDFNEDQKKAIETAYAMVKHSPSVAKI
CLIHGPPGTGKSKTIVGLLYRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMK
KIILEFKEKCKDKKNPLGNCGDINLVRLGPEKSINNEVLKFSLDSQVNHRMKKDLPSHVQ
EMHRRKEFLDRQLDELSRQRALCRGGREIQRQELDEKIAKVSKERQELASKIKEVQGRPQ
KTQSIIILESHVICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIHR
CNKLILVGDPKQLPPTVISMKAQEYGYDQSMMARFYKLLEDNVEHNMIGRLPVLQLTVQY
RMHPDICLFPSNYVYNRSLKTNRQTETNRCSSDWPFQPYLVFDVGDGSERRDNDSYVNVQ
EIKLVMEIIKLIKDKRRDVTFRNIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDGFQ
GRQKDCVIVTCVRANAMQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNHLI
QDAQKRGAIIKTCDKNYRHDAAKILKLKPVLQRSLTHPPAIAPEASRPQDGLLSGKLDSE
FAKTSFTSSLYHTASDSKESAGTVTTKDPERPPIQDRLRDPRLLRRLGMDPEARGTCLRE
PQPLSPQHLGATPPSGEPGFPMSHQDPGGVPQATTQGATPNNHRPHVQGEPPAAGTDVPT
SKRKGDWEAGLSHRRESRAFSEGDQESWSPNSKHSRRNLDWDRRGLEKDDSGSKKRKLL
NT seq
8100 nt
NT seq
+upstream
nt +downstream
nt
atgcttcaaaagaggtgcagaatgagcacatgttgttggtgtacgccaggtggcatttcc
accgttgacttcctgcagcggtatgcatccaagatctactccagtgagtttcaaacagct
gatgaagacctctgctactgcttagagtgtgtgactgaataccacaaagcaagggatgag
ctgccattcttgcatgaggttttatgggaattagaaaccttacgtctcataaatcacttt
gaaaaatccatgaaggcagaaattggagacgatgatgaattgtatatagtagacaataat
ggagaggcacagctgtttgactttactggccaagactttgaaaataagcttcgagttcct
cttcttgaaatactgaaatatccttatctgcttttacatgagcgtgttagtgaactgtgt
gttgaagcactttgtcggatggaacaagctaattgctcctttcaggtttttgacaaacat
ccaggcatctatctgtttttggtccatcccaatgaaatggttcggcgttgggctatcctc
actgccagaaatttgggaaaagtggacagagatgattattatgacttgcaggaggttttg
acttgcctttttaaagtcatcgagttggggcttttggaaagtccagacatttatacttct
tctgtccttgagaagggtaaactgattcttctgccctcacacatgtatgataccaccaac
tacaaaaactattggttaggtatttgcatgttgctgaccattctggaggagcaggccatg
gactcactgttgctgggctcagacaaacagaatgattttatgcaatcaatacttcacacc
atggagaggcaagcagatgatgatagtgtggatcctttctggccagcgttacactgtttc
atggtgattctggatcgccttggatctaaggtctggggtcaacgtattgatcctattgag
gcatttcagaccattatcaacaatgtaagctacaatagagagatccaaaatatacggaac
agctctgtaaggaccaagttagagccggagtcatattcggatgatatggtgacttgcagc
cagattgtatacaactataatcctgaaaagaccaaaaaggattcagggtggagatcagcc
atttgcccagattattgtcctaacatgtatgaagagatggaaacattagccagtgtgctt
caatcagatattggtcaagacatgcgtgttcataacagcacatttctgtggttcatccct
tttgttcagtccctaatggatcttaaggatttgggtatggcttacatagtagaggttatt
catcatctgcactccgaagtcaaagatgtcctcaaccaaacagatgccatatgtgacaaa
gttactgaattttttcttctgattttggtgtctgtgattgagctgcatagaaataaaaag
tgtttgcatttgctgtggattagttcccagcagtgggtagaagctgttgtaaaatgtgcc
aagcttcctactacggcattcacaaggaattctgagaaatcatctggaaattgctccaag
ggaacagcaatgatctcatctctgtctttgcattcaatgccgtcaaattctgtacagctg
gcttgtgtgcagctgattagaagtctccttaaagaaggttatcagcttgggcagcaaact
ctatgtaagcgattctgggataagctcaacttatttctgcgtggaaatttatctctaggt
tggcagttgactactcaggagacccatgaattacaagcttgtttaaagcaaattattaaa
aacattaaagtcaaagtacctcaatgtagcaattttgtggatctgagtcctacatgtaaa
agctctcctgtatcttacaataaagaagaaagtgaacaaatagagaggaagtctaaaaaa
gaccttttctgtctggaaaactccagtccaacatttcctaaagaatcaattaaagctgag
atgtatcaaatgcaagagaacatactgattaaagcaagtaacaccgtagaagaggataat
gaacaaaattacataaaagatttgaagctagaagatctctcagccgagtcatgcataaag
cagagtagtaaaagccttttcactgaaagagctcaagatcaagttaaaataagtacagag
aagccgaagtctgtgaaagagaattgtacttcaagaagtgtactgcagaattttacttca
agaaatggtccagaaagggcatgtgacagaggaataataacacatttgttgaccgattcc
agcaccgattctctagagaagatgtccacatcaaatgaggatttctctttcaaggatgat
gttcttggcaaaacctcaaaaacaaaaattaagtcacagaaagatgaaatctgtgctaag
ttatcacacgtaataaagaagcaacacaggaaaagtacttttatcgatgatattggtaat
ttagaggaaaacctgactgtatctaatgttgacaatttctattcaaggaaagagtcaggc
gatcagaaaggggatagcttcatgcacagtctctctttagaccctaatggcattctagat
gataaaaatggggaacaaaaatctcataagagtctattgctgaaaaagaaacagttaaag
agtgaagagtttgatatcttctcttaccatgaaaacagttatcaaatacaggaatgtcat
actgatgataaagatttggtctcatttacagaaatgaccaatacttttgtgaagaaaact
tctcccttcaaagatcctgtgactgtgactgttcttgagtcaagagataaggaaattagc
aagagtaccagtccggtatcttctcacttgagagaacgcattcctggcctcagtcctcag
tctgacaccttaacagattctcagatagacagagacctccacaagttatctttaatagct
caagccagcgttattaagttcccatcagattcaactcaaaaaagctcctcccagctacga
agaaaagtaaaagacagatgtttcctggccgaccagaataatactggggaagcctgttgg
ggccaggttatcattatttcagattctgatgatgatgatgatgatgaagaagaagaagaa
gaaggaattctgggttttgagaaacctataaaacaagataaaataggcatcaagaaagaa
tatctgaagcagcatacttcaatagctagtacgaatgtggaaaagaagctaatgaaggaa
gaggagacccttctgcagtttgaggaatcagattctcagttttttgagtttgaaagtcca
tgtgaagtgttttcagtttggcaagatcaggaacccgacaagaattcagttcaagagggt
gaaaaaaattcacgttcgactgacatagctgatctcatgaatgattggggttatgagaca
gattatgtatctgaagaggttattaagaaagtagcagagggcattgaaaaacatacagaa
ccacagagtagttctgttggggaattttgtaaaattgaagtaaaaaaacgtaagagaaaa
cgatttgagaaacctgtggctgaagatcctgtacggccttcatcatctgagagaaatgag
gaccagcctgatattcttaatgggagaggtctgactgaaaatgatttaaaaaatagggac
ctgaggatggcaagtcccagttcaagtgctcgtagagacaaaaacactacagtttcacta
aagaagtcttctccaaagcttcgtacttattccaaacccattaggagagtcccactttct
aaaactcccaagaagacacattcagataccaaaaaaggacagagtaaaaattctaattac
ataagttgtagaacaactcctgctgtagttccaccgaagaaatttcgccagtgccctgaa
ccaacttcgacagttgagaaacttggcctgaaaaaggctcctcgtagggcatttgagttg
tcccagcgatctctagattatttagttcaattacgtgaccacggcaaaactgttggagtg
gttgatactagaaaaaagacaaagttaatttctcctcagactctctctgtcagaaacaat
aagaaactgctgaccagtcaggatcttcagtttcgaaggcagatgagacccaaatcacaa
caaaataaaaaaggacttttggattatgaaagtaaagagactacaagagcaggtcctcgt
ccagcacagaattctgacatacttgtcccagaatccgatagctcagattatagttctaaa
ggaggaactgaggtggttgctaacaacactgggaaacaattaataaaatgtgtgtcttcg
gaaccagaacccataaaaacaaaatgtgcctctcgagtgactgatgatacttgtcttttg
aaccagtgtgcctctgttgtgttaaatggaagaataccaacaaatgaagtcattgtctct
ccatcagcagaccccttagctggaggtgacccaacaatacatcatttagagttggcaact
ttgaaagagggagagcctgaatacaacagtgatacagaagatgagaatatatttctaacc
cagcaccatcctgaagatatggatttatgttcacagatggagaatggtaatgagaaactc
attgaaatagttcatagaagagatacagctcaggtggaagaagattctgtaggtcagcct
cagttggcatcgtggagtagcacaaaatgtaagtacaaagattgtgttgaaaccccggaa
aaccagggtgaatactgctcaaaacactgtgaagctaaagcagcagatgaagatgtattt
cgtaaacctgccttgcctctttctgcatctaagccttcgagaccttccactgctaagatt
tttagctccagcagcacgtcacgaattgctggtctttccaagtctttggagagttcctcg
gggcttccaccagctctaaaaaataagtcaaatgggggacaggctattttgaaagcccca
cagcctgtctctctattgtctccaaaggcagtgggtgaagtgaagagtctgtgcaatgtt
cttcatcctcagactccaaataattccaacaggcaaggttacaaactgacatttggtgaa
aacaaatctttctcagcttcctctccagtaaacattctcttgtcatcacagtccatttct
gacacctttgtcaaagagatcttaaaatggaagtacgaaatgttcgtcaactttgatcag
tgcgggcccccagcaagcctttgtcagtccatctcaagacctgtgcctgtcagatttcaa
gattgtggagattattttaatgttttcttccctttgatgatattgaatacttttgaaacc
gtggcacaggagtggatcagctctccaaacaaagagaaattctatcagttgcatttacga
aaatttcctgctgattataaaaaatattgggagtttgtggttcatcttgaagaatgtgaa
ctagccaaacagcttcatccaaaggaaaatgatttggtgtttttgatttctgaaagacaa
aatggagagaagaaagatacagagagaaatcgcatgcaggatctccgtgaatatcattgc
ggttatgttcataagtttcgccgcacttcagtcatgcgcaacgggaagtctgagtgtttc
ctttacatccagactcaagataatttgccagtcaatttaaatgaattcgtgaaatgtgtt
gtaatcagttctctggtaactacgcaaaggaagttgaaagccatgtctctgttgagtgga
cggaaccaactggccagagctgttcttaatccaaatcccatggacttctgtacaaaagat
ttactaactacaacgtctgagagaattgtcgcctacttaagagatttcaatgaagaccaa
aagaaagcaatagaaactgcatatgccatggtcaaacactccccgtcagttgccaagatc
tgtctgattcatggaccaccaggaacagggaaatcaaaaactattgttggcctcctgtac
cgcctcctgacagagaaccagaggaaagggcattcagatgaaaactccaatgccaaaatc
aaacaaaaccgtgtccttgtgtgtgcaccttccaacgcagctgttgatgaacttatgaaa
aaaatcatccttgaatttaaagaaaaatgtaaagacaagaagaatcctttgggaaactgt
ggagatataaatttagttcgtctgggtccagaaaagtctattaataatgaagtcctaaaa
ttcagtttggatagccaagttaaccacagaatgaaaaaagacttaccctctcatgttcag
gagatgcacagaagaaaggaatttctggatcgtcaacttgatgaactttcccgccaacgt
gctttatgccgaggtggaagggaaatacagaggcaagaattagatgaaaaaattgcgaaa
gtttcaaaagagaggcaggaactagcttccaaaattaaggaggttcaaggacgcccacaa
aaaacacagagcatcatcatcttagagtcccatgttatctgctgcacattgagcacgagt
ggtggtttactgcttgagtctgcttttcgtgggcaagggggtgtccccttcagttgtgtc
attgtcgatgaggccggtcagtcttgtgaggttgagactctgactccgctcatccatcgt
tgtaacaagctcatcctcgtaggagatcctaaacagctccctcccaccgtcatttctatg
aaagcacaggaatatggctatgaccaatcaatgatggcacgcttctacaagctgctagaa
gacaatgtggagcacaatatgatcggcaggctgcctgttttacagttgactgttcagtac
aggatgcatccagacatatgtctcttcccctctaattatgtttataacagaagcttgaaa
acaaatagacagactgaaaccaatcggtgttcatcagactggccatttcaaccttacctg
gtgtttgatgtcggagacggttcagaaagacgggataatgactcatatgtaaatgttcaa
gaaataaaactggtaatggaaataattaaacttattaaagacaaaagaagggatgttact
ttccggaacattggcataataacccattacaaggctcagaagacgatgattcagaaggat
ttggacaaagagtttgatagaaaagggccagcagaagtagataccgtggatgggttccag
ggccggcagaaggattgtgttattgttacatgtgtcagagcaaatgccatgcagggctca
attggatttctggcaagtttgcagagactgaatgtcaccatcacacgagccaagtacagt
ctcttcatcctcggacatttaaggaccctgatggaaaatcagcactggaatcacctgatt
caggatgcacagaagcggggcgccatcatcaagacctgtgacaagaactataggcacgat
gcggcgaagattctgaagctgaagcctgtgctgcagagaagtctgactcaccctcctgcc
atagccccggaggcatccagaccccaggatggcttgctcagcggcaagctagacagtgag
tttgccaagacctctttcacgtcttccctgtatcacacggcatctgactccaaggaatct
gctgggactgtcactacaaaggaccccgaaaggcctcccattcaggaccgactgcgggac
ccacgactgcttcggaggttgggcatggaccccgaggccagagggacgtgcttgcgggag
ccgcagcccctgagcccccagcatcttggagcaacacctccctcaggagagccaggcttc
cccatgagtcaccaggacccagggggtgtgccccaggccaccacccaaggagccacgcca
aacaaccacagacctcacgtgcagggcgagcctccagcggcgggcacagatgttcccaca
agtaagaggaaaggtgactgggaagcagggctgagccacagaagagagagcagggccttc
agtgaaggggaccaggagagctggagccccaacagcaagcactcgaggaggaacctggac
tgggacaggagagggctggagaaggatgacagtggctctaagaaaagaaagcttttatag
DBGET
integrated database retrieval system
