Canis lupus dingo (dingo): 112677986
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Entry
112677986 CDS
T08371
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
clud
Canis lupus dingo (dingo)
Pathway
clud00260
Glycine, serine and threonine metabolism
clud00630
Glyoxylate and dicarboxylate metabolism
clud00670
One carbon pool by folate
clud01100
Metabolic pathways
clud01200
Carbon metabolism
clud01230
Biosynthesis of amino acids
clud01240
Biosynthesis of cofactors
clud01523
Antifolate resistance
clud04981
Folate transport and metabolism
Module
clud_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
clud00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
112677986 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
112677986 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
112677986 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
112677986 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
112677986 (SHMT2)
Enzymes [BR:
clud01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
112677986 (SHMT2)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SHMT
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
112677986
NCBI-ProteinID:
XP_025332671
Ensembl:
ENSCAFG00020023922
LinkDB
All DBs
Position
10:1619291..1624443
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AA seq
505 aa
AA seq
DB search
MLPFSLLWATRPLQRCGRLVRMAARCQHNEVAQTQTREVASRGWTGQESLSDSDPEMWEL
LQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLC
QRRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSD
VKRVSATSIFFESMPYKLNPKTGLIDYDQLALTARLFRPRLIIAGTSAYARLIDYARMRE
VCDEVKAHLLADMAHISGLVAAKVIPSPFKHADVVTTTTHKTLRGARSGLIFYRKGMRAV
DPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPTFREYALQVLKNAR
AMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAI
TPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVHIGLEVKNKTAKLQDFKSFLLKDSETS
HRLADLRQRVEQFARAFPMPGFDER
NT seq
1518 nt
NT seq
+upstream
nt +downstream
nt
atgctgcccttctctttgctctgggccactcggcctctgcagagatgtgggcggctggtc
aggatggccgcccggtgccagcacaacgaggtggcccagacccagaccagagaagtggcg
agcaggggctggacaggccaggagagtctgtcagacagtgatcctgagatgtgggagctg
ctgcagagggagaaggacaggcagtgtcgtggcctggagctcattgcctcagagaacttc
tgcagccgagctgcgctggaggccctggggtcctgtctgaacaacaagtactcggagggt
tatcctggcaagagatactatggaggagccgaggtagtggatgagattgagctgctgtgt
cagcgcagagccctggaggcctttgacctggatcctgcacagtggggagtcaatgtccag
ccctactcaggctctcccgctaatctggctgcctacacagccctcctgcagcctcatgac
cgaatcatggggctagacttgcccgatgggggccatcttacccatggctacatgtctgat
gtcaagcgggtctcagccacgtccatcttctttgagtccatgccctacaagctgaatcct
aaaaccggcctcattgactacgaccagctggcactgaccgctcgacttttccggccgcgg
ctcattatagccggtaccagcgcctatgctcgcctcattgactatgcccgcatgagagag
gtgtgtgatgaggtcaaggcacacctgctggcagacatggcccacatcagtggcctggtg
gctgccaaggtgatcccctcacctttcaagcatgcggatgttgtcaccaccaccactcac
aagactcttcgaggggccaggtcaggactcatcttctaccgcaaggggatgcgggctgtg
gaccccaagactggccgggagatcccttacacgtttgaggaccgaatcaactttgctgtg
ttcccatccctgcagggcgggccccacaaccatgccattgctgccgtggctgtggcccta
aagcaggcctgcacccccacattccgggagtacgccctgcaggttctgaagaatgctcgg
gccatggccgatgccctgctagagcgaggctactcgctcgtgtctggtggcaccgacaac
cacctagtgctagtggacctgcggcccaagggcctggatggagctcgggctgagcgggtg
ctggaactggtatccatcacagccaacaagaacacctgtcctggggaccgaagcgccatc
acacctgggggcctgcggcttggggccccagccttgacctctcgacagttccgtgaggat
gacttccggagggtcgtggactttatagatgaaggtgtccacattggcttggaggtgaag
aacaagacggccaaactccaggatttcaaatctttcctgctcaaggactctgaaacaagt
catcggctggccgacctcaggcagcgggtggagcagtttgccagggccttccccatgcct
ggttttgatgagcgctga
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