KEGG   Canis lupus dingo (dingo): 112677991
Entry
112677991         CDS       T08371                                 
Symbol
LRP1
Name
(RefSeq) prolow-density lipoprotein receptor-related protein 1 isoform X1
  KO
K04550  low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor)
Organism
clud  Canis lupus dingo (dingo)
Pathway
clud04148  Efferocytosis
clud04979  Cholesterol metabolism
clud05010  Alzheimer disease
clud05144  Malaria
Brite
KEGG Orthology (KO) [BR:clud00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    112677991 (LRP1)
 09150 Organismal Systems
  09154 Digestive system
   04979 Cholesterol metabolism
    112677991 (LRP1)
 09160 Human Diseases
  09174 Infectious disease: parasitic
   05144 Malaria
    112677991 (LRP1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    112677991 (LRP1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:clud04131]
    112677991 (LRP1)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:clud04090]
    112677991 (LRP1)
Membrane trafficking [BR:clud04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Low-density lipoprotein receptor (LDLR) family proteins
    112677991 (LRP1)
CD molecules [BR:clud04090]
 Proteins
  112677991 (LRP1)
SSDB
Motif
Pfam: Ldl_recept_a Ldl_recept_b FXa_inhibition DUF5050 cEGF Vgb_lyase SGL EGF_CA EGF_LRP2 EGF
Other DBs
NCBI-GeneID: 112677991
NCBI-ProteinID: XP_048971668
Ensembl: ENSCAFG00020023946
LinkDB
Position
10:1522299..1602997
AA seq 4561 aa
MLTPPPLLLLPLLSALAAAAIDAPKTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEA
PEICPQSKAQRCQPNEHNCLGTELCVLMSRLCNGVQDCVDGSDEGPHCRELQRQCSQLGC
QHHCVPTLNGPTCYCNNSFQLQADGKTCKDFDECSVYGTCSQLCTNTDGSFTCGCVEGYL
LQPDNRSCKAKNEPVDRPPVLLIANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYTNE
TVCWVHVGDSAAQTQLKCARMPGLKGFVDEHTINISLSLHHVEQMAIDWLTGNFYFVDDI
DDRIFVCNRNGDTCVTLLDLELYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDGQNRTK
LVDSKIVFPHGITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTIIQGILIEHLYGLTVFE
NYLYATNSDNANAQQKTSVIRVNRFNSTDYQVVTRVDKGGALHIYHQRRQPRVRSHACEN
DQFGKPGGCSDICLLANSHKARTCRCRSGFSLGSDGKSCKKPEHELFLVYGKGRPGIIRG
MDMGAKVPDEHMIPIENLMNPRALDFHAETGFIYFADTTSYLIGRQKIDGTERETILKDG
IHNVEGVAVDWMGDNLYWTDDGPKKTISVARLEKAAQTRKTLIEGKMTHPRAIVVDPLNG
WMYWTDWEEDPKDSRRGRLERAWMDGSHRDIFVTSKTVLWPNGLSLDIPAGRLYWVDAFY
DRIETILLNGTDRKIVYEGPELNHAFGLCHHGNYLFWTEYRSGSVYRLERGAGGAPPTVT
LLRSERPPIFEIRMYDAQQQQVGTNKCRVNNGGCSSLCLATPGSRQCACAEDQVLDTDGV
TCLANPSYVPPPQCQPGEFACANSRCIQERWKCDGDNDCLDNSDEAPALCHQHTCPSDRF
KCENNRCIPNRWLCDGDNDCGNSEDESNATCSARTCPPNQFSCASGRCIPISWTCDLDDD
CGDRSDESASCAYPTCFPLTQFTCNNGRCININWRCDNEKDCGDGSDEKTCPEPADNDCG
DNSDEAGCSHSCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCH
NDEFQCRLDSLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPNVKFGCKDSARCISKAW
VCDGDSDCEDNSDEENCESLACRPPSHPCANNTSVCLPLDKLCDGNDDCGDGSDEGELCD
QCSLNNGGCSHNCSVAPGEGIVCSCPLGMELGPDNHTCQIQSYCAKHLKCSQKCDQNKFS
VKCSCYEGWVLEPDGESCRSLDPFKPFIIFSNRHEIRRIDLHKGDYSVLVPGLRNTIALD
FHLSQSALYWTDVVEDKIYRGKLLDNGALTSFEVVIQYGLATPEGLAVDWIAGNIYWVES
NLDQIEVAKLDGTLRTTLLAGDIEHPRAIALDPRDGILFWTDWDASLPRIEAASMSGAGR
RTIHRETGSGGWPNGLTVDYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFA
VTLYGGEVYWTDWRTNTLAKANKWTGHNVTVVQRTNTQPFDLQVYHPSRQPMAPNPCEAN
GGRGPCSHLCLINYNRTVSCACPHLMKLHKDNTTCYEFKKFLLYARQMEIRGVDLDAPYY
NYIISFTVPDIDNVTVLDYDAHEQRVYWSDVRTQAIKRAFINGTGVETVVSADLPNAHGL
AVDWVSRNLFWTSYDTNKKQINVARLDGSFKNAVVQGLEQPHGLVVHPLRGKLYWTDGDN
ISMANMDGSNRTLLFSGQKGPVGLAIDFPESKLYWISSGNHTINRCNLDGSELEVIDAMR
SQLGKATALAIMGDKLWWADQVSEKMGTCNKADGSESVVLRNSTTLVMHMKVYDESIQLE
HEGTNPCSVNNGDCSQLCLPTSETTRSCMCTAGYSLRSGQQACEGVGSFLLYSVHEGIRG
IPLDPNDKSDALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTISRAKRDQTWREDVVTNG
IGRVEGIAVDWIAGNIYWTDQGFDVIEVARLNGSFRYVVISQGLDKPRAITVHPEKGYLF
WTEWGQYPRIERSRLDGTERVVLVNVSISWPNGISVDYQDGKLYWCDARTDKIERIDLET
GENREVVLSSNNMDMFSVSVFEDFIYWSDRTHANGSIKRGSKDNATDSVPLRTGIGVQLK
DIKVFNRDRQRGTNVCAVANGGCQQLCLYRGGGQRACACAHGMLAEDGASCREYAGYLLY
SERTILKSIHLSDERNLNAPVQPFEDPEHMKNVIALAFDYRAGTSPGTPNRIFFSDIHFG
NIQQINDDGSGRTTIVENVGSVEGLAYHRGWDTLYWTSYTTSTITRHTVDQTRPGAFERE
TVITMSGDDHPRAFVLDECQNLMFWTNWNEQHPSIMRAALSGANVLTLIEKDIRTPNGLA
IDHRAEKLYFSDATLDKIERCEYDGSHRYVILKSEPVHPFGLAVYGEHIFWTDWVRRAVQ
RANKYVGSDMKLLRVDIPQQPMGIIAVANDTNSCELSPCRVNNGGCQDLCLLTHQGHVNC
SCRGGRILQEDFTCRAMNSSCRAQDEFECANGECINFSLTCDGVSHCKDKSDEKPSYCNS
RRCKKTFRQCNNGRCVSNMLWCNGADDCGDGSDEVPCNKTACGVGEFRCRDGTCIGNSSR
CNQFVDCEDASDEMNCSATDCSSYFRLGVKGVRFQPCERTSLCYAPSWVCDGANDCGDYS
DERDCPGVKRPRCPLNYFACPSGRCIPMSWTCDKEDDCEHGEDETHCNKFCSEAQFECQN
HRCISKQWLCDGSDDCGDGSDEAAHCEGKTCGPSSFSCPGTHVCVPERWLCDGDKDCADG
ADESVTAGCLYNSTCDDREFMCQNRQCIPKHFVCDHDRDCTDGSDESPECEYPTCGPNEF
RCANGRCLSSRQWECDGENDCHDQSDEAPKNPHCTSPEHKCNASSQFLCSSGRCVAEALL
CNGQDDCGDGSDERACHVNECLSRKLSGCSQDCEDLKIGFKCRCRPGFRLKDDGRTCADV
DECSSTFPCSQRCINTHGSYKCLCVEGYAPRGGDPHSCKAVTDEEPFLIFANRYYLRKLN
LDGSNYTLLKQGLNNAVALDFDYREQMIYWTDVTTQGSMIRRMHLNGSNVQVLHRTGLSN
PDGLAVDWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVSSGLREPRALVVDVQNGYLYWTD
WGDHSLIGRIGMDGSGRSVIVDTKITWPNGLTLDYVTERIYWADAREDYIEFASLDGSNR
HVVLSQDIPHIFALTLFEDYVYWTDWETKSINRAHKTMGTNKTLLISTLHRPMDLHVFHA
LRQPDVPNHPCKVNNGGCSNLCLLSPGGGHKCACPTNFYLGSDGRTCVSNCTASQFVCKN
DKCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQCSTGICTNPAFICDGDNDCQDNS
DEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCAPNQFQCSIT
KRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDG
SDEPKEECDERTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSCA
NGRCIAGRWKCDGDHDCADGSDEKDCTPRCDMDQFQCKSGHCIPLRWRCDADADCMDGSD
EEACGTGVRTCPLDEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEECARFVCPPNRPFRC
KNDRVCLWIGRQCDGTDNCGDGTDEEDCEPPTAQTPHCKDKKEFLCRNQRCLSSSLRCNM
FDDCGDGSDEEDCSIDPKLTSCATNASICGDEARCVRTEKAAYCACRSGFHTVPGQPGCQ
DINECLRFGTCSQLCNNTKGGHLCSCARNFMKTHNTCKAEGSEYQVLYIADDNEIRSLFP
SHPHSAYEQAFQGDESVRIDAMDVHVKAGRVYWTNWHTGTISYRSLPPAAPPTTSNRHRR
QIDRGVTHLNISGLKMPRGIAVDWVAGNVYWTDSGRDVIEVAQMKGENRKTLISGMIDEP
HAIVVDPLRGTMYWSDWGNHPKIETAAMDGTLRETLVQDNIQWPTGLAVDYHNERLYWAD
AKLSVIGSIRLNGTDPIVAADSKRGLSHPFSIDVFEDYIYGVTYINNRVFKIHKFGHSPL
INLTGGLSHASDVVLYHQHKQPEVTNPCDRKKCEWLCLLSPSGPVCTCPNGKRLDNGTCV
AVPSPTPPPDAPRPGTCNLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWEYCRNG
GTCAASPSGMPTCRCPTGFTGPKCTQQVCAGYCANNSTCTVNQGNQPQCRCLPGFLGDRC
QYRQCSGYCENFGTCHMAADGSRQCRCTAYFEGPRCEVNKCSRCLDGACVVNKQSGDVTC
NCSDGRVAPSCLTCVGHCSNGGSCTMNSKMMPECQCPPHMAGPRCEEQVVSQQQPGHMAS
ILIPLLLLLLLLLVAGVVFWYKRRVRGAKGFQHQRMTNGAMNVEIGNPTYKMYEGGEPDD
VGGLLDADFALDPDKPTNFTNPVYATLYMGGHGSRHSLASTDEKRELLGRGPEDEIGDPL
A
NT seq 13686 nt   +upstreamnt  +downstreamnt
atgctgaccccgccgccgctgctgctgctgcccctgctctcagctctcgccgcggccgct
atcgacgccccgaagacttgtagccccaagcagtttgcctgcagagaccagatcacctgt
atctcaaagggctggcggtgtgacggtgagagggactgcccagatggatccgatgaggcc
cctgagatttgtccacagagcaaggcccagcgatgtcagccgaatgagcacaattgcctg
ggtaccgagctgtgtgttctcatgtcccgcctctgcaatggggtccaggactgcgtggat
ggttcagacgaggggccccactgccgagagctccaaagacagtgttctcagctgggctgc
cagcaccactgtgtccccacactcaacgggcccacctgctactgcaacaacagctttcaa
ctgcaggcagatggcaagacctgcaaagactttgacgaatgttcagtgtacggcacctgt
agccagctatgcaccaacacggacggctcctttacatgcggctgtgtggaagggtacctc
ctgcagccagacaaccgctcctgcaaggccaagaatgagccagtagatcggccccctgtg
ctgctgattgccaactcacagaacatcctggctacgtacctgagtggggcccaggtgtct
accatcacacccacgagtacacggcagaccacagccatggacttcagctacaccaacgag
actgtgtgttgggtgcatgttggggacagcgccgcccagacacagctcaagtgcgcccgc
atgcctggcctgaagggcttcgtggatgagcacaccatcaacatctccctcagtttgcac
catgtggagcagatggccatcgactggctgacaggcaacttctactttgtggatgacatc
gatgataggatcttcgtctgcaaccgcaatggagacacgtgtgtcactttgctggacctg
gagctctacaaccccaagggcattgcactggaccccgccatggggaaggtgttcttcact
gactatgggcagatcccaaaggtggagcgctgtgacatggatggacagaaccgcaccaag
ctggttgatagcaagatcgtgtttcctcacggcatcacgctggacctggtcagccgcctc
gtctactgggctgacgcctacctggactacatcgaggtggtggactacgagggcaagggc
cgccagaccatcatccagggcattctgattgagcatctgtacggcctaaccgtgttcgag
aactacctctatgccaccaactcagacaatgccaacgcccagcagaagacgagcgtgatc
cgggtgaatcgattcaacagcaccgactaccaggtcgtcacccgtgtggacaagggtggt
gcgcttcatatctaccaccagcggcgtcagccccgggtgaggagccacgcctgtgagaat
gaccagtttgggaaaccaggaggctgctctgacatctgcctgctggccaacagccacaag
gcacggacctgccgctgccgctccggcttcagcctgggcagtgatgggaagtcatgcaag
aagccagaacacgagctgttccttgtgtatggcaagggccggccaggcattatccggggc
atggatatgggggccaaggtcccagacgaacacatgatccccatcgagaacctcatgaac
ccccgggccttggacttccatgctgagaccggcttcatctactttgccgacaccaccagc
tacctcattggccgccagaagattgatggcacagagcgggagaccatcctgaaggacggg
atccacaatgtggagggggtggctgtggactggatgggggacaacttgtattggacggat
gatggacccaagaagaccatcagtgtggccaggctggagaaggctgctcagacccgcaag
accttaatcgagggcaaaatgacacaccccagggccattgtggtggatcccctcaatggg
tggatgtactggacagactgggaggaggaccccaaggacagtcggcgagggaggctggag
agggcctggatggacggctcacaccgagacatctttgtcacctccaagacagtgctttgg
cccaatgggctgagcctggacatcccagctgggcgcctctactgggtggatgccttctat
gaccgcattgagaccatactgctcaatggcacagaccggaagattgtatatgagggtcct
gagctgaaccacgcctttggcctgtgtcatcatggcaactacctcttctggactgagtac
cggagcggcagtgtttaccgcttagaacggggcgcaggcggggcgccccccaccgtgacc
cttctgcgcagcgagcggcctcccatctttgagatccgcatgtatgatgcccagcagcag
caagtgggtaccaacaagtgccgagtgaacaacggtggctgcagcagcctgtgcctggcc
acccctgggagccgccagtgtgcctgtgctgaggaccaggtgttggacacagatggtgtc
acctgcttggcgaacccgtcctacgtgcccccaccccagtgccagccgggcgagttcgcc
tgcgccaacagccgctgcatccaggagcgctggaagtgcgacggggacaacgattgcctg
gacaacagcgacgaggccccggccctctgccatcagcacacctgcccctccgaccggttc
aagtgtgagaacaaccggtgcatccccaaccgctggctctgtgacggcgacaacgactgc
gggaacagtgaagacgagtccaatgccacttgttcagctcgcacctgcccacccaaccag
ttctcctgtgccagcggccgctgcatccccatctcctggacgtgtgatctggacgatgac
tgtggggaccgctccgatgagtcggcctcgtgtgcctatcccacctgcttccccctgact
cagtttacctgcaacaatggcagatgcatcaacatcaactggcgatgtgacaatgagaag
gattgtggggacggctctgacgaaaagacctgtcctgagcctgccgacaatgactgtggg
gacaacagtgatgaggccggctgcagccactcctgctccagcactcaattcaagtgcaac
agtgggcgctgcatccctgagcactggacctgtgatggggacaatgactgcggagactac
agtgatgagacccatgccaactgcaccaaccaggccacaaggcctcctgggggctgccac
aatgatgagttccagtgccggctggatagtctctgcatccccctacggtggcgctgtgac
ggcgacactgactgcatggactccagtgatgagaaaagctgtgagggagtgacccatgtc
tgtgaccccaatgtcaagtttggctgcaaagactctgctcgatgcatcagcaaagcatgg
gtgtgtgatggcgacagtgactgtgaagataactcggatgaggagaattgcgagtccctg
gcctgcaggccaccctcgcacccctgcgccaacaacacctcagtctgcctgcccctcgac
aagctgtgtgatggcaacgacgactgtggagatggctcggatgagggagagctctgcgac
cagtgctccctgaacaatgggggctgcagccacaactgctcggtggcacctggcgaaggc
attgtgtgttcgtgcccgctgggcatggagctggggcccgacaaccacacctgccagatc
cagagctactgtgccaagcatctcaagtgcagccagaagtgcgaccagaacaagttcagc
gtgaagtgctcctgctacgagggctgggtgctggagcccgacggcgagagctgccgcagc
ctagaccccttcaagccgttcatcatcttctccaaccgccacgagatccggcgcatcgac
ctccacaagggggactacagcgtgctggtgcccggcctgcgcaacaccatcgccctggac
ttccacctcagccagagcgcgctctactggaccgacgtggtggaggacaagatctaccgc
gggaagctgctggacaacggagccctgactagcttcgaggtggtgattcagtatggcctg
gccacccccgagggtctggctgtcgactggattgcaggcaacatctactgggtggagagt
aatctggaccagattgaggtggccaagctagatgggacccttcggaccacccttctggcc
ggtgacattgagcacccgagggcaattgcactggatccacgggatgggatcctgttttgg
acagactgggatgccagcttgccccgcatcgaggccgcctccatgagtggagctgggcgc
cgcaccatccaccgggagacaggctctgggggctggcccaatgggctcactgtggactac
ctggagaagcgcatcctctggatcgatgccaggtcagatgccatttactcagcccgttac
gacggctccggccacatggaggtgcttcggggacacgagttcctgtcgcacccgtttgca
gtgacgctgtatgggggggaggtgtattggacggactggcggacaaacacgctagccaag
gccaacaagtggaccggccacaatgtcaccgtggtacagaggaccaatacccagcccttt
gacctgcaggtgtaccacccctcccggcagcccatggctcccaatccttgtgaggccaat
gggggccggggcccctgctcccacctgtgtctcatcaactacaaccggaccgtctcctgc
gcctgcccccacctcatgaagctccacaaggacaacaccacctgctatgagtttaagaag
ttcctgctgtacgcacgtcagatggagatccggggggtggacctggatgccccctactac
aactacatcatctccttcacggtgcctgacatcgacaacgtcacggtgctggactatgat
gcccacgagcagcgcgtctactggtccgatgtgaggacacaggccatcaaaagggccttc
atcaatggcacgggcgtggagaccgtcgtctctgcagacttgccaaatgcccacgggctg
gctgtggactgggtgtcccgaaacctgttctggaccagctatgacactaacaagaagcag
atcaacgtggcccggctggacggctccttcaagaatgcagtggtacagggcctggagcag
ccccacggccttgttgtccacccgctgcgtgggaagctctactggacggatggggacaac
atcagcatggccaacatggacggcagcaaccgtaccctgctcttcagtggccagaagggc
cctgtgggcctggctatcgacttccctgagagcaaactctactggatcagctccggaaac
cacaccatcaaccgctgcaacctggacgggagtgagctggaggtcatcgatgccatgcgg
agccagctgggcaaggccactgccctggctatcatgggggacaagctgtggtgggcggat
caggtgtcagagaagatgggcacctgcaacaaggctgacggctcggagtccgtggtcctg
cggaacagcaccaccctggtgatgcacatgaaggtctatgacgagagcatccagctggag
cacgaaggcaccaacccctgcagtgtcaacaacggtgactgctcccagctctgcctgcct
acgtctgagacgacccgctcctgcatgtgcacagccggctacagcctccggagtggccag
caggcctgcgagggtgtgggttcctttctcctgtactctgtgcacgaaggaatccgggga
atccccctggatcccaatgacaagtcagatgccctggttccagtgtcggggacctccctg
gctgtcggcattgacttccatgctgaaaatgacaccatttactgggtggacatgggccta
agcaccatcagccgggctaagcgagaccagacatggcgtgaggatgtggtgaccaacggc
attggccgcgtggagggcattgcagtggactggatcgcaggcaacatctactggacggac
cagggctttgacgtcatcgaggtggcccggctcaatggctctttccgctatgtggtcatc
tcccagggtctggataagccccgggccatcactgtccacccagagaaggggtatctgttc
tggactgagtggggccagtacccacggattgagcggtctcggctagacgggactgagcga
gtcgtgctggttaatgtcagcatcagctggcccaatggcatctcggtggattatcaggat
gggaagctgtactggtgcgacgcccggacagacaagattgagcggattgacctggagacg
ggagagaaccgtgaggtggttctgtccagcaacaacatggacatgttctcggtgtctgtg
tttgaggatttcatctactggagtgacaggactcatgccaatggctccatcaaacgtggg
agtaaagacaatgctacagactctgtgcccctgagaacaggcattggtgtccagctcaaa
gacatcaaagtcttcaatcgggaccggcagagaggcaccaatgtgtgtgcagtggctaat
ggtgggtgccagcagctgtgcctgtaccggggcggcgggcagcgggcctgcgcctgcgcc
catgggatgctggctgaagacggggcatcgtgccgcgagtacgccggctatctgctctac
tcggagcgtaccatcctcaagagcatccacctgtctgacgagcgcaacctcaatgcaccc
gtgcaacccttcgaggatcctgaacacatgaagaatgtcatcgctctggccttcgactac
cgagcaggcacctccccgggcacccccaatcgcatcttcttcagcgacatccacttcgga
aacatccagcagatcaatgacgatggctcggggaggaccaccattgtagagaacgtgggc
tctgtggaaggcctagcctatcaccgtggctgggacactctctactggacaagctacacc
acatccaccatcacccgccacacggtagaccagacccggccaggggccttcgagcgcgag
acagtcattaccatgtccggagacgaccacccgcgggcctttgtgctggatgagtgccag
aacctgatgttctggaccaactggaacgagcagcaccccagcatcatgcgggcagccctg
tcaggagccaatgtcctgactctcatcgagaaggacatccgcacccccaacggcctggcc
atcgaccaccgtgccgagaagctctacttctccgatgccacactggacaagatcgagcgg
tgcgagtatgacggctctcaccgctatgtgatcctgaagtcggagccagtccaccccttc
gggttggctgtgtacggggagcacatcttctggaccgactgggtgcggcgagctgtgcag
cgggccaacaagtacgtgggcagcgacatgaagctgctgcgtgtggacatcccccagcag
cccatgggcatcatcgccgtggccaatgacaccaacagctgcgagctctccccttgccgc
gtcaacaacgggggctgccaggacctgtgtctgctcactcaccagggccatgtcaactgc
tcctgccgagggggtcgcatccttcaagaggacttcacctgccgcgccatgaactcgtct
tgccgagcacaggatgagttcgagtgtgctaacggcgaatgcatcaacttcagcctgact
tgtgacggtgtctcccactgcaaggacaagtctgacgagaagccgtcctactgtaactca
cgccgctgcaagaagactttccgccagtgcaacaacggacgctgtgtgtccaacatgctg
tggtgcaacggggcggacgactgcggggacggctcagacgaggttccctgcaacaagacg
gcctgtggcgtgggcgagttccgctgccgggacggcacctgcattggcaactccagccgc
tgcaaccagttcgtggactgtgaggacgcctctgacgaaatgaactgcagtgccacggac
tgcagcagctacttccgcctgggagtgaaaggtgtgcgcttccagccctgtgagcggacc
tccctctgctacgcccccagctgggtgtgtgacggtgccaacgactgtggggactacagc
gatgagcgcgactgcccaggagtgaagcggcccagatgccccctgaattacttcgcctgc
cccagtgggcgctgcatccccatgagctggacgtgtgacaaggaggacgactgtgagcac
ggcgaggatgagacccactgcaacaaattctgctcggaggcccagtttgagtgccagaac
catcgctgcatctccaagcagtggctgtgtgatggcagtgacgactgtggggacggctca
gacgaggcggctcactgtgaaggcaagacatgcggcccctcctccttctcctgccccggc
acccacgtgtgcgtccccgagcgctggctctgtgacggtgacaaggactgtgctgatggt
gctgacgagagcgtcacagctggctgcttgtacaacagcacctgcgacgaccgcgagttc
atgtgccagaaccgccagtgcatccccaagcacttcgtgtgcgaccacgaccgcgactgc
actgatggctccgacgagtcccccgagtgtgagtacccgacctgcggccccaacgagttc
cgctgtgccaacgggcgctgcctgagctcccgccagtgggagtgcgacggcgaaaatgac
tgccacgaccagagcgacgaggcccccaagaacccgcactgcaccagcccagagcacaag
tgcaacgcctcctcacagttcctgtgcagcagcggacgctgcgtggccgaggcgctgctc
tgcaacggccaggacgactgcggggacggctccgacgagcgtgcctgccacgtcaacgag
tgtctcagccgcaagctcagtggctgcagccaggactgcgaggacctcaagattggcttc
aagtgccgctgccgcccgggcttccggctgaaggacgacggccgcacgtgtgccgacgtg
gacgagtgcagctccacgttcccctgcagtcagcgctgcatcaacacgcacggcagctac
aagtgtctgtgtgtggagggctacgccccccgcggtggcgacccccacagctgcaaggct
gtgactgacgaggagcccttcctgatctttgccaaccggtactacctgcgcaagctcaac
ctggatggctccaactacacgctgctcaaacagggcctgaacaacgccgtggctttggac
tttgactaccgagagcagatgatttactggacggacgtgacaacccagggcagcatgatt
cgaagaatgcacctgaatgggagcaacgtgcaggtgctgcatcggacaggcctcagcaac
cccgatggactggctgtggactgggtgggcggcaacctttactggtgtgacaaaggccgg
gacaccatcgaagtgtccaagctcaacggggcctaccggacggtgctggtcagctcaggc
ctccgtgagcccagggctctggtggtggatgtacagaacgggtacctgtactggacagac
tggggtgaccactcactgatcggccggataggcatggatgggtctggccgtagtgtcatc
gtggacaccaagatcacgtggcccaacggcctgacactggactacgtcaccgagcgcatc
tactgggctgatgcccgtgaggactacattgagtttgccagcctggatggctctaatcgc
catgtcgtgctgagccaggacatcccgcacatcttcgcgctgaccctgtttgaggactat
gtctactggaccgactgggagacaaagtccatcaaccgagcccacaagaccatgggcacc
aacaagacgctcctcatcagcaccctgcaccggcccatggatctgcatgtcttccacgcc
ttgcgccagccagacgtacccaatcacccctgcaaggtcaacaatggtggctgcagcaac
ctgtgcctgctgtcccctgggggaggccacaaatgtgcctgtcccaccaacttctacctg
ggcagcgatgggcgcacctgtgtgtccaactgcacagcaagccagtttgtgtgcaagaac
gacaagtgcattcccttctggtggaagtgtgacacggaggacgattgcggggaccactcg
gacgagcccccggactgccctgagttcaagtgccgcccagggcagttccagtgttccaca
ggcatctgcacaaaccctgccttcatctgtgacggggacaacgactgccaggacaacagt
gatgaggccaactgcgatatccacgtctgcttgcccagtcagttcaagtgcaccaacacc
aaccgctgcattcctggcatcttccgttgcaatgggcaagacaactgcggggacggggag
gacgagagggactgccccgaggtcacctgtgcccccaaccagttccagtgctccatcacc
aagcgctgcatcccccgagtctgggtctgtgaccgggacaacgactgtgtggacggcagc
gatgagcccgccaactgcacccagatgacctgcggagtggatgagttccgctgcaaggac
tcgggccgctgtatccccgcacgctggaagtgtgacggagaggatgactgtggggacggc
tccgacgagccaaaggaagagtgtgacgagcgtacctgtgagccctaccagttccgctgc
aagaacaaccgttgcgtgccaggccgctggcagtgcgattacgacaacgactgtggggac
aattcagacgaggagagctgcacccctcggccctgctccgagagtgagttctcctgcgcc
aatggccgctgcattgctgggcgctggaaatgtgatggggatcacgactgtgcggatggc
tccgatgagaaagactgcactccccgttgtgacatggaccagttccagtgcaagagcggt
cactgcatccccctgcgctggcgctgtgatgcagatgccgattgcatggatggcagcgac
gaggaagcctgtggcactggcgtgcggacctgccccctggacgagttccagtgcaacaac
actctgtgtaagccactggcctggaagtgcgacggcgaggacgactgcggggacaactcc
gatgaaaaccccgaggagtgcgcccggtttgtgtgtcctcctaaccggcccttccgttgc
aagaacgaccgcgtctgcctgtggatcgggcgccaatgtgatggcaccgacaactgtggg
gacgggacagacgaggaggactgtgagccccccacggcccagaccccccactgcaaagac
aagaaggagtttctgtgccggaaccagcgctgcctttcctcctcgctgcgctgcaacatg
ttcgacgactgcggggacggctctgacgaggaggactgcagcatcgaccccaagctgacc
agctgtgccaccaacgccagcatctgtggggacgaggcccgctgcgtgcgcaccgagaaa
gccgcctactgtgcctgccgctctggcttccacaccgtgcctggccagcccggatgccag
gacatcaacgagtgcctgcgcttcggcacctgctcacagctctgcaacaataccaagggt
ggccacctctgcagctgcgctcgcaacttcatgaagacacacaacacctgcaaggccgaa
ggctctgagtatcaagtcctctacatcgccgacgacaatgagatccgcagcctgttcccc
agccacccccattcggcttatgagcaggccttccagggtgatgagagcgtccgcatcgat
gccatggatgtccatgtcaaggctggccgtgtctattggaccaactggcacacaggcacc
atctcctaccgcagcctaccccctgccgcgcctcccaccacttccaaccgccaccggcga
cagattgaccggggtgtcacccacctcaatatttcaggactcaagatgccaaggggtatc
gccgtcgactgggtggctgggaacgtgtactggactgactcgggccgagatgtgattgag
gttgcacagatgaagggcgagaaccgcaagacactcatctcgggcatgatcgacgagccc
cacgccattgtggtggacccgctgaggggcactatgtactggtcagactgggggaatcac
cccaaaattgaaacagcagcaatggacgggacccttcgagagacactggtgcaggacaac
atccagtggcccacaggcctggctgtggattatcacaatgaacggctctactgggcagat
gccaagctctcagttatcggcagcatccggctcaatggcacggaccccattgtggccgct
gacagcaaacgaggcctaagtcaccccttcagcatcgatgtctttgaggattacatctat
ggcgtcacctacattaataatcgtgttttcaagatccataagtttggacacagccccctg
atcaacctgacggggggcctgagccacgcctctgacgtggtcctgtaccaccaacacaag
cagcccgaagtgaccaacccctgtgaccgcaagaagtgtgagtggctctgcctgctgagc
cccagtgggcctgtatgcacctgtcccaacgggaagcggctggacaatggcacctgtgtg
gctgtgccctcgccaacgcccccaccagatgcgcctcgacccggaacctgtaacctgcag
tgcttcaatggtggcagctgcttcctcaatgcgcggaggcagcccaagtgccgctgccag
ccccggtacacaggcgacaagtgtgagctggaccagtgctgggaatactgtcgcaatgga
ggcacctgcgctgcctccccctccggcatgcccacgtgccggtgccccacgggcttcacg
ggcccaaaatgcacccagcaggtgtgtgcgggctactgtgccaacaacagcacctgcacc
gtcaaccagggcaaccagccccagtgccgatgtctacctggcttcctgggggaccgctgc
cagtaccggcagtgctccggctactgtgagaactttggcacctgccacatggccgccgac
ggctcccggcagtgccgctgcaccgcctacttcgagggaccaaggtgtgaggtaaacaag
tgcagccgctgtctcgacggagcctgtgtggtcaacaagcagagtggggacgtcacctgc
aactgctctgacggccgggtggcccccagctgcctgacctgcgtcggccactgcagcaat
ggtggctcctgcaccatgaacagcaaaatgatgcccgagtgccagtgtccaccccacatg
gcagggccccggtgcgaggagcaggtggtcagccagcagcagcctggacatatggcctcc
atcctaatccctctgctgctgctgctgctgctgctgctggtcgctggagtggtattctgg
tacaagcggcgggtccgaggggctaagggcttccagcaccagcggatgaccaatggggcc
atgaatgtggagattgggaaccccacctataagatgtatgaaggcggggagcctgatgat
gtggggggcctactggacgctgactttgcactggaccctgacaagcccaccaacttcacc
aaccccgtgtacgccacactctacatgggtggtcacggcagccgccactccctggccagc
acggacgagaagcgagaactcctgggccggggccccgaggacgagataggggaccccttg
gcatag

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