Cyclopterus lumpus (lumpfish): 117727052 Help Entry 117727052         CDS       T09199                                  Symbol syne1a Name (RefSeq) nesprin-1 isoform X1   KO K19326   nesprin-1 Organism clum  Cyclopterus lumpus (lumpfish) Pathway clum04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:clum00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     117727052 (syne1a)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:clum03036]     117727052 (syne1a) Chromosome and associated proteins [BR:clum03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     117727052 (syne1a) SSDB OrthologParalogGFIT Motif Pfam:  Spectrin SYNE1 Spectrin_SYNE1 KASH Spectrin_SYNE1_2 SR_desmoplakin_3 Motif Other DBs NCBI-GeneID:  117727052 NCBI-ProteinID:  XP_034382937 LinkDB All DBs Position 24:complement(11150328..11229770) Genome browser AA seq 6579 aa AA seqDB search MQVLESDLKKKIAHAQEVYNQAKHTLTYFSFQKQRLEDLMSQMAERLVAVEGSLSDLTEA TSPEDMGTVKDLQSVVHQQRADMDSARDTLSALCRSHPSQELSCLSSDLTSIAKRTEAVA QRCAKTKGSLQDGLQLHFNELVQDFHSRLTDLRLELKECSNQSGDVAVLGAKLQRLQVSV ERKSEGEECFSTVCEEAERLQLHLPKAGAAQIREHLSSCQKEWRSYLDCCSQSQRDLEES IDLMNNFNECVEGVRDCLKQMDLSLKREPVLGAECQQGAPDTTEELERIENLHEELLARR DSIEHLCQEAQSLSEVGRGSGEEVRVTGQLQMEHQALLKTARDKLRGCQDSQAFGETLQG VWAWLEEIQERLGTVDSTMGTKEQLEQRLETVQDILLLKGEGEVKLNMAMGKGELALRSY GATGQEVVRSQLQEVEDAWATLLVTAMSCHSRLEWTVSQWGGYLESAAQLRCWMEAVERE VCAPLTPQPGPREKASQLERLRALLADLEDHQVALSSLEEKARELFKKTGDASFNHGART QLQVQFDDLTALVEERVRLAQAVVLEHQEYLEAVRELTDWLMSAGEELHHWSDTSGDSAS IKKKLSEVRERVECQLLEGRERLSRVRRSAASTAEHTAAGGCEAMDRQLGALSQALEQWE GAALRARDDMEGSLAAATASEEEYHGLTTRLEDELKELDGRLRVWSQELIKAEGRSNGEE AVEGWQLAKNILEGLQSAEPMAEKLKGQLNDLVRYSRDLGSQSDRVTALIKQHNSLSLRA SRECQNKERLLEQKFRAALRDFQQWLVNAKISTAKCFDVPQSVAEAFTALQRIQEFLSDR EHGQARLSTVGASGELLMAVVSKDRVEGIKAKVANAREDWKSLMNNLKMREDALKNLQSQ MTEFEASAEPLQDWLNSTEVRVQESSARLHDLPAKKKELSKLQCVLEEKTSREAELGRLR ERAHRLWEGQAAGKGFVHRVSQLSAQYLALSNLTKDKASRIERIVGEHRLFSQGLKELQD WVCEAQRVLKTCISTTTDKGVLEDRMLQLEALLAARQEREIQLKMLLTRGEAVQRNTSAE GVPVIRKQIQDLKDSWDFLLSASIQCKSQLEGALSQWTSYQEDVGQFVMWMDRVEETLSC SDRQYSEMRDKTANLGKTKLLYEEVLSHSSPLDTIATKGSNMAEHYTTKQEVQQLQCRYN TLKEKTKNAVSKAKGLVLVHQEYQRGLHVFEDWLEQEQATLAALSHPEGNVDTLEKTLQQ LQLLQECCSNGQSLLSSVLTSRERVIPWGIPQIEDRVLDTAQQEWGAYQGRLGETQTQLS STLTRLRQIGQRFLSLAQWLEEMEKVANIRSHRRSDRGTKETQLKKLTWCLEAVLARQGE VDGLSSLAQQVLEETYISSRVSVTATQLTARYHSLLLNIQDTIKQLQEELKSIEEAENLC TSFTDWFGSTKKSFTALTDTSEPLDRVAMEKKMKKLETLQSELQRGHCFLKSLRERAERA AGFLDEARAEILGGEVEARLAQLEELSGGLRQEHSFLQRALLLAKEFQDRYKAQAQWLVE TRALLKSPLEPKAELYQRRALLAKYKTLLQMVQSHDESIRSVVEKGDALLASVHYPSIRD KMNRMQKDYTELCHTATAHVENLEGQVKEQEVYHNELQEVERWLLQMSSRMVTPDPTVGG SLEAATQQLSRHKAIMEEIAGFEDRLAGLKKRGDHLVQGCSDRVQSRLRQQVQAHHQGTR DSYSAICSTAQRVYQSLDHELQRHVSLQDTLLQCQTWLTSVSEEPEPPAHPPLSLEEALQ QVKQERALQEQASTYLQLVCSICDLSELKVRGTAAAIQQVKLQIEERMLLCDEVADSWRD IEEQKADLEVQLRETEQQLQNLIRRPAELEPKIAQNQLDKAQEFLQQIRERQSEVSHLND AVGKMTDGQVSPALEEIRRLRRSWMDLGQRAEDLEAQRGEDMQRSGEYQEIVVAVEELFH QVSREWDYLARADTESTSEHLEALRKLSSDLEEQRTTLEDLREQRQAILPRLSLLDKELI KQQVGHLEQRWAQLETLIQRKIQDSSQTLEDLARVETQLKDAREWVEEQRPAFTSALKTS PPPDMAQSFLFDHLSVCVELEARQQLLGQAVSEAQAVASRLGLSEKRFLQELVEQAQTEV EALGARVAQRRKYLSKAFTERTQFLQGLGRALSWIQQQERRALIDDHIALLPDDLAKQVA VCRGVQCGLRVYQRELASLWIQGREIERDATDKERAETVARLEKLQAVFETALHRTSQRL TDLEKALTSRKYFQVDLDKTCHWLRRADAITFPEINFSNIDDSLELQTQLSNFQNVLEQA SEYENLLLIVQRIGQEILPTLNEIDHCYLDERLNALPQQYNAILALAKEKKDRVQQVILE RKEFSTFFDITRNALEELQEQFDNLEKQTISISKEEFVFCLINEYRNIKESVFHISPAVR ELHGKTEGFLSWGQQFRAAETLQLVNLHNTLKRMNDQKIKHLEDCLKTLVEHNKISTKLD SEFKSVEEKLVRLKSDTEQGAIDRITSLYSLLESLDCVSSQAEECNQQTKGLGLKFDPNA FQETKLQLESLQSLRCEVKCLMDESETITRNEDFAEETEKMLEWLRTIKDKVEEPLILSE VRIERVNEEVRKLKIVEEEEKSRCRIGDALGSRVKQKYFSKKKTVPANIEEKLQELAKLG AEVQQGISRKELAVDRVLSLVQRHHLSLQSMQTRLDSAAALLQRASSGVDLENQTDCVWD VEDILAQEKNFTTGLTKMRALDPLLEDFMKAEAMGKFREKVGAMLLRNTEVKQQLDAYRE TLQSCTALWTSFQHERETLVEQMNDAEAKMAMFTTAKAVSIQQAEEKCQRYKSLVAHIDL LEMPLKALKENTIELEQKISESSKAVTSHSVSSLWQRWTRLRSVARAQERALEDTAREWR NFTDKMEKVRSVSQDLHSRVPDSTVEKAATRAALQSLLEYNDSFGLEVEREQSILALLGQ HTRCLRGEEEEEEVMKKKSENGFEETPCLQQIRSMQEQYDSLVLRVRASRAHVHQELRER EEVEKELGLVKGWIQDTRGLLLSPTADLESLLQELETAHGQVISRRQSVERMTELQQSKY QELQAGLPSELSMQLAEVALALGSAEDQVQAREREVQQTRDVKEDFHFRLQDIEAKMKTI ALKLEDKGADLEEAKEETKALCEECQCCGRSVADLGIAVQEFGEQNPLLCKQLGDAVAKL TEVQRHTTQQVQDRANRLKKAERQVEEYQGMKAFILGWTEKAEALVTGCIIWGSASQLQE QIRAHQALLRECRGLHGDLEAMGEREGQLGEVLQTEGWIQQVKHLSRHTEELQQTAKTRL QSLQDAAKDMLLLEAEVKILHAAVDQIQITLASPDLNRLSLREQLTQRQRLLVEMEGFKQ QVAAVQQCQSALRLPLEVVASLPICRTAQILQQEASQLQHTTIQQCNILQEAVVQYEQYE QEVKNLQRLIEEAHRIIQDRPVSTNNIQELQAQIHHHEELAQKIRGYQEQIASLHSKCKM LTVKAKHATMLLTVNEVDGLSDGMDELSDEELPGSVATTNTAANKQLPAHPSVVMMTAGR CHTLLSPVTEESGEEGTNSEVSSPPACRSPSPGANADAPLSQGRGALSRAPLRELYDPSM ETSAANLDDLQRSWETLKNVISEKQKSLYEALERQQHYQESLQSISTKMESIEGALSEGL EPNKSPESQMAAHQALMDEILMLQDEIGELQTCFSEELADSDSDGEAGDQLALQSTLTVL GERMATIRMKASGKRQLLEEKLSEQLEEQRQEQALQRYHSEAEELDHWLLSTRATLRSAL QPQNEDLDMEEQLIDCQNMLFEIEQKVSYLSELSVHSESLLLEGRAETKGEAEQLTFKLH SLKDSLMELQQMLQDKQVGIQVRSKGSLQEQEDSEPDSSLSQSPNVQDWLSQARSTRTQQ YHDNLLRQRELQEQVAEQKRLLQSVASVGEELLQQTTPNGDSEVSIPGGVLLESVTVSPL DQMRQRWENLNKDQSTKLQLSLNSMEQDQLSPVLHRSRLSSPSVVFRGISSSQDSRSPKA LFEACSQTLERIARETADGESKLATSLGGTSVQQELYAAVSAASSWLDAAENQLLAGPVL LSEDTETQLSNLEGLNKQLKAMTWEVNQCRDLLGGGAGRLCGGEEQALMEDTLEGLQERM GLLDSTLDQHCDAMRDRLQEYSTFQNELRLLFTSLGESKHLLLQKMAGTVDRPASKQIET LTEVEESLREFEQRVTELKTRAEGLQSDQISNQELLKLQDAYEELVLMVGSRRSSLNHRL SLKAQYEAALHDLTDLVDTAQDKMAADQKMTVASVIEVQMLLDKHKEFFQGLECHMILTQ AFYSKVSGLVAQRESQALEESMALAHSVLKQAHRRGVELEGILESWSGLVEDYQAVCRQL EAVECSIPTVGLVEETEERLVERIGLFQRLKASLTEHQSQLYQVLEEGKRLLLSVGCSDL ENQLTQLGDHWLSSTTKVNKELHRLDSTLKHWSRYQCESAELSHWLHSALDQLEFWTTQS VTVPQELETVRDHLYAFLEFSKEVDAKSSLRSSVLSTGNQLLRLKRVDTAGLRTALGHID THWAELLTRIPVVQEKLHQLQMEKLASRHAITELMSWISLLENLIQEDQYKIMGAVGSVL VHDFLQKYKGFRIDLTCKQLTVDFVNQSVLQISSQDVEGKRSDKTDFAEKLGAMNRRWQI LQGLIAEKIQLLEGLLEGWLEHENGVQALNTWLTLQEDKLKKRHRIEDVASVQNALKDCQ ELEELVEEKEKDLEKAEERGNALIQNKTGVACSVVKETLKGLNQSWAHLNHMISQMKVSL RSMLEQWTLYRRALEEMNGYLMEGRYSVSRLCLLNGSLEAVQQQVESLENLQYEMDKQES SLKKFGSVTQQLLTECHPSVAETLNTALQDINIRWNSLLEQISEQLRSSKALLGLWQRYR SSCGQCVTLVQKQEERADRLLKSATDREITEEESSAWIMDCDVCLGDQASVQQSLKQLQA LGEQLKSQVDSSSSAALQSDHLSLTQRLGTLEHALHRQQEVLQSGSQACEGFREQLDTLI RKAEEADEVLKEPDPVGSPAIIVVQTRMEKLKVYLLRLSSLSPDLERVNESVYRLPVSDR DVKRLQSLNRAWATHSAHLTERFSKLQAVLLQQQSFLQKCEVWMEFLSQTEQKLAAEISG NYLNLLEQQRDHELFQAEMFSRQQILYSIINDGHHMLDQGQVDDRDDFSVKLALLGNQWQ GVVRRAQQRRGIIDSLVRQWQKYREMAEKLLQWLQEVTRDPDEHQPGEPVALQQARNLLD QIQLRERVLQRQQGGYILTVEAGRSLLLTADARAESTLQTELMDIQERWRHAHHRLDQQR RELHGLLKNWERCEKGINASLEKLRAFKRKLSLLLPDHHEELHSEQIRCKELESSVEGWT DDLTSLFLLRDTLEGVVSADDITVLQERLQLLQRQWGEVCHQLSLRRQQVSEKLNEWAVF NEKNKELCEWLTQMESKVSQNGDISIEEMIEKLRKEYQEEIGVAQENKQQLQIMGARLAR SSQDGKAAEIQHKLSKVSERWQHLLDLIAARVKKLRETLVAVQQLDKNMSSLRSWLAHIE TELSRPIVYDTCDDQEIQRKLNQQQELQRDIEKHSTGVASVLNLCEVLLHDCDACSTETE CDSIQQATRGLDRRWRNICAMSMERRLKIEETWRLWQRFLDDYSRFEDWLKTSERTAALP NSSGVLYTVAKEELKKFEAFQRQVQECLTQLELINKQYRRLARENRTDSSCQLREMVHDG NRRWDNLQRRVAAILRRLKHFISQREEFETARDIILVWLTEMDLQLTNIEHFSECDVQAK IKQLRAFQQEIYLNTGKIELVFRQGDALIEKSEPLDAAVIEEELEELQRYCQEVFGRVDR YYKKLTRLPLADDELDGSDRELDMEEGGELSELQWGDSSLPRTSSRQTSGTTALIRADRS GRDTPASVDSIPLEWDHDYDLSRGLDSPGGRGPGERSHGQEEGDEYLRTAVTVLSDVVIP ESPEAYIKLTENTLKSSSGEAGQLEASLRQLDQALDAGQYHIQQREATVNSSSPDVDSTY MGYMRLMGECRGSIDAVKRAEGELTEDEDDMPGLTNPNSTDTQSAGVIERWELIQAQTLS EKHKHKQNLQQWQQLISDLQTMQDWLGQSEAELNQLRGLDLSTDIHTIQQRIKRLKELLK GVDAHKSEVLSINLSSAEFLQSESDSEEAWELRDRLKEMNTHWDRLGTSLEDWREELQRA LMQCQEFHEMSHGLLLWLENIDRRRNQVVPIPPKLDRETLRAHHRTLTKIKRELLDSQQK VSSLQELSAQLLVNTKPLTLLLQSQAPEQSQAQGSECLEAQEKVHVILNRLRLLLREVSS DLEELERRLETTGTRQDCLPLLPVGKSEICGSAGPASEVTVQSRKRSPRGKSSQAHPGHP KSGPRHSRSRSPGAAGCVSSHSDLPDGVSSSTSSASSKGQSFLLRVLRAALPVQLLLLLL IGLACLVPMSQEDYSCHHANNFARSFHPMLRYTNGPPPI NT seq 19740 nt NT seq  +upstreamnt  +downstreamnt atgcaggtcctggagtcggacttaaagaagaaaatcgcccatgctcaggaggtgtacaac caggccaaacacactctgacctacttcagtttccagaagcagcgattggaggacctcatg tcccagatggccgagcggctggtggcagttgagggctccttatctgacctcactgaagct acatctcctgaagacatgggtacagttaaggacctgcagagcgttgtgcatcaacagagg gcagacatggactcagctagagatacgctgagtgccctgtgcaggtctcatccctctcag gagctgtcatgcctctcctctgacctcacctccattgccaagcgaacagaggccgtcgcc cagcgctgtgccaagaccaagggcagcctgcaggatgggctacagctccacttcaacgag ctcgtccaagacttccactcccggcttacagatctgaggttggagctgaaagaatgttcg aaccaatcgggagatgttgccgtcctcggtgctaagttgcagcggttacaggtgtccgtc gagcggaaatctgagggtgaagagtgtttttctacggtttgtgaggaagccgagaggctt caactccacctgcctaaagctggagcagcacagatccgagagcatctctcctcctgtcag aaagagtggaggagctacctggattgctgctctcagagccaacgagacttggaagagagt attgaccttatgaacaactttaatgagtgtgttgagggtgtaagagactgcctgaagcag atggatctcagcctcaagagagagcctgttcttggggcagaatgccagcaaggagcccca gacaccacagaagagctggagaggatagaaaacctccatgaggaactgcttgcaagaagg gactccatcgagcatctttgccaggaggcccagtctctgtctgaagtaggccgggggtca ggggaagaggtcagagtgacaggccagctccagatggagcaccaggccctgctgaagaca gccagggacaagctgcgaggctgccaagatagccaggcctttggagagaccctccaaggg gtttgggcctggctggaggagatccaggagagactgggtacagtagacagcaccatgggg accaaagagcagttagagcagaggctggagactgtgcaggacatcctgcttttgaagggg gagggggaggtcaagctgaatatggcgatgggtaagggtgagttggccctacgcagctat ggagccaccggacaggaagtggtccgctctcagctacaggaagtagaggatgcctgggcc acgcttcttgtgactgccatgagctgccacagtcgactagagtggaccgtgtcgcagtgg ggaggttacctggagagtgctgcacagctgcgatgctggatggaggctgtagagagagag gtgtgtgcccctctcacccctcagccagggcccagagaaaaggcttcccagctcgagaga ctcagagctctgctggctgatctggaagaccatcaggtggctctgtccagtctagaagaa aaagccagagaactgtttaagaagactggcgatgccagcttcaatcatggtgcccgcacc cagctgcaggtgcagtttgatgacctcacagccttggtggaggagagagtacgtctagcg caggctgttgtgttggaacaccaagaatacctggaggctgttagggagctcactgattgg ctgatgagtgctggagaggagcttcatcattggtctgatacatcaggagactctgcctct atcaaaaagaaactgtcagaagtgagggagcgtgtggagtgtcagctactggagggccga gagcgcctcagcagggtgcgtcggagtgcagcgtccacggctgaacacacggcggcgggt ggctgcgaggccatggaccgacagctgggggcgctgtcccaggctctggagcagtgggag ggggctgccctcagggccagggatgacatggaggggtccctggctgctgctacagcctca gaagaagaataccacggtctgaccacccgcctggaggatgagttgaaagagttggatgga cggctgagggtgtggagccaggagttgattaaagctgaagggcggagcaacggggaggaa gcagtagagggatggcagctggctaagaatatactggagggcttgcagagcgccgagccg atggcagagaagttgaaaggccaacttaacgacctggtgcgatactccagggacctgggc tcacaatcagaccgggtcaccgcgcttatcaaacagcacaacagtctcagtcttcgtgca tccagggagtgtcaaaataaggagcgcttgttggagcagaagttccgtgcagccttgaga gacttccagcagtggttggtcaatgccaaaatcagcacagccaaatgctttgatgtgcca cagagtgtcgccgaggccttcaccgctctgcagaggatccaagagttcttgagtgacagg gagcatggccaggccaggctgagtacagtaggagccagtggggagctgctgatggctgtg gtgtccaaagacagagtcgagggaattaaggccaaggtggcaaacgccagagaagactgg aagagcctgatgaataatctgaagatgagggaggatgcactcaagaacctgcagtcccag atgacggagtttgaggccagtgctgagcctctgcaggactggctgaacagcacagaggtc agagttcaggagagcagtgctcgtctacacgatcttccagccaagaaaaaggagctcagc aaactacagtgtgtactggaggagaagactagtcgggaagcagagctgggcaggctgagg gaaagagctcatcgtctctgggagggacaagcagccggcaagggcttcgtccaccgtgta tcccagctgtcagcacagtacctagccctcagcaacttaaccaaggacaaggcctccagg attgaacgtattgtaggagagcatcgtctcttctctcaaggccttaaagagctccaggat tgggtgtgtgaagcacagagggtcctcaaaacatgcatctccaccaccactgacaagggt gtgctagaggaccggatgttacagctggaagccttactggctgctcgtcaggagagggag atccagctaaagatgcttctgacgcggggagaagccgtccagaggaacacttcagctgag ggggtcccagtaattcgcaaacagatccaggacctcaaagactcatgggacttcttgctt tctgcctccattcagtgcaaaagccagctggagggtgcattgtctcaatggaccagctat caggaagacgtgggtcagtttgtgatgtggatggaccgggtggaggagacactcagctgc tctgacagacagtactctgagatgagagacaagaccgccaacctgggaaagaccaagctt ctctatgaagaagtactgagtcacagcagtcctttggacaccattgccacaaaggggtcc aatatggcggaacactacactaccaagcaggaggtgcagcagctgcagtgtagatacaac accctcaaagaaaagaccaagaatgcggtcagtaaggccaaggggctggtgctggtccat caggaatatcaaagggggttacatgtgtttgaggactggctggagcaggaacaggcaact ctggctgcgttgtcccatccagagggaaacgtggataccctagagaagacactgcaacag ctacagctcctgcaggaatgctgttcaaatggccagtctttgctctcctctgtgctgacc agcagagagagagtaatcccctggggtatacctcagattgaggacagagtgctggacact gctcagcaggagtggggggcctaccagggccgtctgggggagactcagacccagctgagc tccacactgaccagactgaggcagataggtcaaaggttcctgagcctggcccagtggctg gaggagatggagaaggtggcaaacatcagaagtcatcggcggtcagacagaggcaccaag gagactcagctgaagaaactcacgtggtgtcttgaggcagtgcttgcacggcagggagaa gtcgatggcctttcctctttggcccaacaggttctggaggaaacttacatcagtagtcgt gtcagcgttactgccacccagctcactgcccgctaccattccctgctgctcaacatacag gacaccatcaagcagcttcaggaggagctgaagagcatcgaagaggctgagaatctttgc acgtccttcactgactggtttggctccactaagaagagcttcacagcattaaccgacact tctgaacctcttgaccgggtcgccatggagaagaagatgaaaaaactagagactctccag tctgagctccaacgcggtcactgtttcctgaaatccctgagggagcgggcagagcgggca gcaggcttcctggacgaggctagagctgagattttaggaggggaggtagaggctcgtctt gcccagctggaggagctctcaggtgggctgaggcaagagcacagctttctacagcgggcg ttactgctagctaaggagtttcaggaccgatacaaggctcaggcccagtggctggtggag accagggctttgctcaaatcccctctggagcccaaggctgaactgtaccaacggagagca ctgttggctaaatataagactctgctgcagatggttcagtcccatgatgaatccatcagg tcagtggtggagaaaggagatgctcttctggcctctgtgcactacccctccatcagagac aaaatgaacaggatgcaaaaggactacactgaactctgtcatactgccacggcccatgtg gagaatctggaaggccaggtgaaggaacaggaagtttaccacaacgagctccaggaagtg gagcgctggctgctccagatgtccagcagaatggtgactcctgatcccactgtgggtggc agcctggaggcagccactcaacagctgtccaggcacaaggccatcatggaggaaatagcg ggctttgaggatcgcttggcaggcctaaagaagcgaggagaccacctggtacaaggctgc agtgaccgcgtgcagagcaggctgagacagcaggtccaggcgcaccatcaaggcaccaga gacagctactcagccatctgtagcacagcacagagagtgtatcagagtctggaccatgag ttacagagacatgtgagtctccaagacacactgttgcagtgccagacctggttaacttct gtctcagaggaaccagaacctcctgcacatcctcctctcagcctggaggaggcgctacag caggtgaagcaggaacgagctctccaggaacaggccagcacttacctccagcttgtgtgc tcaatatgtgacttgtccgagctgaaggtcagggggaccgcagcagctatccagcaggtc aaactgcagattgaggagcgcatgctgctctgtgatgaggtagcagacagctggagggac attgaggagcagaaggcagatctggaggtccagctgagagagacagagcagcaacttcaa aacctcataagaagacctgcggagttggagcccaagattgcacaaaaccagctggacaaa gcacaggaattccttcagcagattagggagagacagtctgaagtatcccatttaaatgat gccgttggtaagatgacagatggacaggtctctcctgccctggaggagataaggagactg aggagaagctggatggatctgggccagcgggcagaagacctggaggctcagcggggggag gacatgcagcgaagtggggagtaccaggagattgttgttgctgtggaggaactcttccac caagtatccagggagtgggactacctcgcaagggctgacacagagagtaccagtgagcat ctggaggctctgaggaagctctccagtgacctagaagagcagagaacaactctggaagac ctcagagaacagagacaagctatcctgccgcgactcagcctgctagacaaggagctgatc aagcaacaggttggtcatctggagcagcgctgggcccagcttgaaaccctgattcaaagg aagatccaggactcctcacagacactagaggatcttgcccgggttgaaacccagctaaag gatgcccgagagtgggtggaggagcagcggcctgcttttacttctgcgctgaaaaccagc ccaccgcccgatatggcccagagtttcctgtttgaccacctgagtgtgtgcgtcgaactg gaggcccgtcagcagctgctgggtcaggcagtaagcgaggcccaggctgtggcttccaga ctggggctgagtgagaagagattcctacaggagctcgttgaacaagcccagacggaagtg gaggctctgggggctcgagtggcccaaaggaggaagtaccttagtaaggccttcacagag aggacacagttccttcaaggtctggggagagcactgtcttggatacagcaacaggagagg agggctttgatagatgaccacatagcgcttctacctgatgacctagccaaacaggttgct gtttgtcgaggcgtccagtgtggtttacgagtgtaccagagagagctggcatctctctgg atacaagggcgagaaatagaacgagatgccactgacaaagagagagcagaaactgtggcg agacttgagaagctgcaggcagtatttgaaactgctctccataggacaagccagcgtctc acagacttagagaaagccttgacctccaggaagtacttccaggttgacctggataagacc tgccactggttgagacgagcagatgcaatcactttccctgaaatcaatttcagcaacatt gacgatagcttggagttgcaaacacaactgtctaactttcagaatgtcctagaacaagct tcagagtacgagaaccttcttcttatcgtccaaagaataggccaggagatcctccctact ctgaacgagattgatcattgctacctagatgagaggctcaatgccttgcctcagcagtac aatgccatcctagctctagccaaagagaaaaaggacagagtccaacaagtaatcttagag cgaaaagagttcagcactttctttgatatcactcgaaatgcactggaggagcttcaggag cagtttgacaatctggaaaagcagactatcagtattagtaaggaggaatttgtcttttgt ctaattaatgaatacagaaatattaaggaaagtgtattccatattagccccgctgtgaga gaacttcatggcaaaactgaggggtttctcagttggggtcagcaattcagagctgcagag acactgcagctggtcaatctccataacacactgaaaagaatgaatgatcagaaaattaaa cacttagaggattgcttgaaaacactagttgaacacaacaaaatatccaccaagttggac tccgagttcaagtctgtggaagagaagctggtccgacttaagtcagacaccgaacagggt gccatagatagaatcacaagtctttactcactgcttgaaagtctggattgtgtaagctct caggctgaagaatgtaaccaacaaactaaaggccttggtctgaagtttgaccccaatgcc tttcaggaaactaagctgcagctggaatcattgcagtcgttacggtgtgaagtgaaatgt cttatggatgaaagtgaaacaatcacaaggaatgaagatttcgcagaagaaactgagaaa atgttggaatggcttcggactatcaaggacaaagtagaagagcctttgattctttcagag gtcagaattgagagggtaaatgaggaagtgcgcaaactgaagatcgtagaggaggaagag aaaagtagatgtaggataggagatgccttagggagcagagtcaagcaaaagtattttagt aagaagaaaacggttcctgcaaacattgaagagaaactacaggagctggcaaagctggga gctgaagttcaacaaggaattagcaggaaagagctggctgtggatcgagtgctttccctg gtccagagacaccacttatctctgcagtccatgcagacacgtctggactctgctgcagct ttactccagagggccagctcgggggtggatcttgagaaccagacagattgtgtgtgggac gttgaagatattttagcccaggaaaagaactttacaaccggtttaacgaagatgagggct ttggatcctctgctcgaggattttatgaaagcagaagcgatgggcaaatttagagaaaaa gttggggcaatgctgctgagaaacacagaagtcaaacagcaactggatgcttacagagag acactgcagagttgcacagctctatggacctccttccaacatgagagagagacactagtt gaacagatgaatgacgcagaggccaagatggccatgttcactacagctaaagccgtcagt atccagcaagctgaagaaaagtgtcagagatataagtcacttgtggctcacatcgatctg ctcgagatgcctctaaaggctttgaaagagaatacaatagagttggagcagaaaatctct gagtccagcaaagctgtcaccagccactctgtgtcgtcactgtggcaacggtggaccagg ctccgcagtgtggcccgagcccaggagagggcactggaggacactgcgagggagtggagg aacttcactgacaagatggagaaggtgcgctccgtgtcccaagaccttcacagccgtgtc ccagacagcacagttgagaaggctgccaccagggcagcgctacagagcctcctggagtac aatgactccttcggcctggaggtggagagggagcagtccatcctggctctgctggggcaa cacactcgctgcctcagaggagaggaggaggaggaggaggtcatgaagaaaaagtcagag aatggatttgaagagacgccttgcctacaacagattagaagcatgcaggagcaatatgac agccttgtgttgcgggtacgagccagcagagctcacgtacaccaggagttgagggagaga gaagaggtcgagaaggagctgggcttggtcaaaggctggatccaagatacacgtggttta ctgctgagtcccactgcagacctggaatcactgctgcaagagctagagacggcacacggt caggttatcagcaggcgtcagagtgtggagcgcatgacagagctgcagcagtctaagtac caggaactccaggccggtctgccttctgagctcagcatgcagctggctgaggtggctctg gctctgggatcggctgaagaccaggtccaggcgagagaaagggaggtgcagcagaccaga gatgtgaaagaggacttccatttcagactccaggacatcgaggcaaagatgaagaccatc gctctgaaattggaagacaagggtgccgacctggaggaggcaaaagaagagaccaaagct ctttgtgaagaatgtcaatgctgtggtcgctctgtggcagatttaggaatagcagtgcag gagttcggtgagcagaaccctctgctgtgtaagcagctgggcgatgctgtggccaaactg acagaggtgcaacggcacaccacgcagcaggtccaggacagagccaacagactgaagaag gcagagagacaggtggaggaatatcaaggtatgaaggcattcattttgggctggacagaa aaggcagaagctctggtcactggttgtatcatctggggttctgcgtcccagctgcaggag caaattagagcacaccaggcattgctgcgggagtgtcggggtctccatggtgacttggag gccatgggggagagggaggggcagctgggggaggtgctgcagacggaagggtggatccag caggtgaaacacctcagccgacacacagaggagctgcagcaaactgccaagactcgcctc cagagtctgcaggatgcagcaaaggacatgttgcttttggaggcagaggtaaagatcctc catgctgctgtggaccagatccagatcacacttgcctcaccagacctcaacaggctcagc ctcagagagcagctcacacagagacagcgtctgctggtggaaatggagggcttcaagcag caggtggcggcagtacagcagtgtcagagcgccctccggctaccattggaggtagtggcc agcctccctatctgccgcacagctcagattctacagcaagaagccagccaactgcagcac accaccatccagcagtgcaacatcctgcaggaggctgtggtgcagtacgagcagtatgaa caggaagtgaagaacctccagagattaatagaagaggctcaccgcatcatccaggaccgg cctgtctccactaataacatacaggaacttcaggctcaaatacaccaccatgaggagctg gcccagaagatccgcggctaccaggagcagatcgcctcgctccactccaagtgtaagatg ctgacagtgaaagccaaacacgccaccatgctgctgactgtcaacgaggtggatgggctc tcggacggcatggacgagctgagtgatgaggagctgcccggttctgtggcgaccactaat accgccgccaataagcagcttccagcacacccctctgttgtcatgatgacagccggccgc tgccacacacttctctcccctgtgacggaggagtcaggggaggagggcaccaacagtgag gtctcctctccccctgcctgccgctccccctccccaggggctaacgctgacgctcctctt agccagggtcgaggtgccttaagtcgagcgcccctccgggagctgtacgacccgtctatg gagaccagtgctgctaacctggatgacctgcagagatcctgggaaacactgaagaacgtg ataagcgagaagcagaagagtctgtacgaggctcttgagcggcagcaacactatcaggag tccctccagtccatttccacgaagatggaatccattgagggagcgctcagtgagggcctg gagccgaacaagagccccgagagccagatggctgcacaccaggctctgatggatgagatc ctgatgctgcaggatgagattggtgagttgcagacgtgtttctctgaggagctggcagac agcgacagcgatggggaggctggtgaccaactggccctccagtctactctcactgtgctg ggagaaaggatggccaccattcgaatgaaggcttctgggaaacggcagctgctggaggaa aaactaagtgaacagctggaagagcagcgacaggaacaggcgctgcagcgttaccacagc gaggccgaggagctcgaccattggctgctcagcactcgggccactttaagatctgccctt cagccccaaaatgaggacttggacatggaggagcagctcatcgactgtcagaatatgctg tttgagatcgagcagaaggtgtcgtatctgtcagagctgtccgtccacagcgagagctta ctgttggagggtcgggccgagaccaagggagaggcggagcaactcaccttcaaactgcac tccctcaaagacagcctgatggagctgcagcagatgctgcaggacaagcaagttggcata caggtgagatcaaagggttcactgcaggagcaggaggacagtgagccagactcatctctg tcccagagtcccaacgtccaggattggctttcccaggccagatccacacgcacacagcag taccacgacaaccttcttcgacagagggagctgcaggagcaagtagctgaacagaaaagg ctgctccagtctgtagccagcgttggagaggagttactccaacagaccacacccaatggt gacagtgaggtgtccatcccaggaggagtgttgctggagtctgtgaccgtgtctcctttg gaccagatgagacagcgctgggaaaacctgaacaaagatcagagcacaaaactgcagctc tccctcaactccatggaacaggatcagcttagcccggtccttcaccggtcccgcttgtcc agccccagtgtggtgtttagaggcatatcttccagccaagactctcgctctcccaaagct ttgtttgaggcctgcagtcagactctggagagaatcgcccgtgagacggcagatggtgag agcaaactggcaacatctttaggagggacatcagtccagcaggagctgtatgctgcagtt tcagcagcttcctcctggttggatgctgctgagaatcagctgctcgctggtcctgtgctc ctgtctgaagatacagagacacaactttccaatctagagggtctgaataaacagctgaag gcgatgacctgggaggtaaaccagtgcagagaccttctgggtggaggagccggccggctg tgtggaggagaggagcaggccctgatggaggacacactggagggcctgcaggagaggatg gggctgctagactccaccctggaccagcactgtgatgctatgagggacaggctacaggaa tactcaaccttccagaatgaactgagattgctgttcacttctctgggtgaaagtaaacac ctgctgcttcagaagatggctggaactgtggacagacctgcgtccaaacagatagagaca ttaacagaggtagaggagagtctgagagagtttgagcagagagtgactgagctgaagaca agagcagagggactccaatctgaccaaatctccaaccaggaacttctcaaactacaggat gcatatgaggagctggttctgatggtgggttccagacgtagcagcctgaaccacaggttg tctctcaaggctcagtatgaagctgcacttcatgacctcacagacctggtggacaccgcc caggataagatggctgccgatcagaagatgacagtggcttctgtcatagaggtccagatg ttactggacaaacacaaagagtttttccagggtctggaatgccatatgatcctcacccag gcattctacagtaaagtgtctggtttggtggcgcagagggaaagccaggccctggaagag tccatggccttagcccacagtgtgctcaaacaggcccacaggaggggagtggagctggag ggcatactggagtcatggagcgggctggtggaagactaccaggctgtgtgtagacagctg gaggctgtggaatgtagcatccctactgtaggcctggtagaggagacagaggaaagactt gttgaaaggatcggtctcttccagcgtctgaaggccagcttgacggagcatcagtctcag ctgtaccaggtcctggaggagggcaaaaggcttcttctttctgttggctgctcagacctg gagaaccagctgactcagctgggagatcactggctctcctccactaccaaggtcaacaag gagctgcaccgccttgattccacgcttaaacactggagcaggtaccagtgtgagtcagca gagttgagccactggttgcattcggctctggaccagctggagttctggacgacccagtca gtgacagtgcctcaggaactagagaccgtcagagaccacctctatgccttcctggagttt tccaaagaggtggatgctaagtcgtctttgcgttcatctgtgctgagtacaggaaaccag cttctgcgtttgaaaagagtagatactgctggtctcaggacggcattgggccacattgac actcattgggctgaactgttgactcgtattcctgtagtacaagagaagctacaccagttg cagatggagaagctcgcatcccgccacgccatcacagagctgatgagctggatctctctt ttggaaaacctcatacaggaggaccagtacaaaatcatgggagctgtaggctcagtgttg gtccatgacttcttacagaaatataagggtttccgcatagatctgacctgtaaacagttg actgtggactttgtaaaccaatcagtgctgcagatcagcagtcaagatgtggaggggaaa cgcagtgacaaaacagactttgctgagaaactgggagctatgaacagacgatggcagata ctacaggggctcattgctgaaaagattcagcttttggaaggacttttggaaggttggttg gagcatgaaaatggagttcaggccttgaatacctggctcacgctacaggaggataaactg aagaagagacaccggatagaggatgtggcatctgtgcagaatgcacttaaagactgtcag gagttggaggaattagtggaggaaaaagagaaggatctagagaaagcagaggaacgagga aatgctctcatccagaataagacaggagtggcttgctctgttgtcaaggagacccttaaa ggactgaaccaatcctgggctcatttgaaccacatgataagccagatgaaggtgagcctg cggtcgatgctggagcagtggacgctgtaccggcgagctttagaggagatgaatggttac ctgatggaggggaggtactctgtgtccaggctgtgtctcctaaacgggtctctagaggca gtacagcaacaggtggagagtctggagaacctgcagtacgagatggataaacaggagagc agcctgaagaagtttggctctgtaacacaacagctcctgacagagtgccacccatctgtt gctgaaacactcaacacagccctccaggacattaacattagatggaacagtctgctagag cagatctcagaacagctgaggagcagtaaggccctgcttgggctgtggcagcgctacagg tcatcgtgtggccagtgcgtgacattagttcagaaacaggaagaacgtgctgatcgcctg ctgaagagcgccaccgacagggagatcacagaagaggagagcagcgcctggataatggac tgtgatgtgtgccttggggaccaggcctcagtgcaacagtccctgaagcagctacaggct ttaggggagcagctgaagagccaagttgactcctcctcttctgcagcgctccagtccgac cacctgtcactcacacaacgtctaggaacactggagcacgcccttcacaggcagcaggaa gtactgcagtctggatctcaggcctgtgagggtttcagagagcagttggacacactgatc cgtaaggctgaggaggctgatgaggtgcttaaggagcccgacccagtcggctcaccggcg atcattgtggtccagacacgtatggaaaaactaaaggtttacctgttgaggctgagcagt ctatctccagacctggagcgtgttaacgagtcggtgtacagactgccagtcagtgacaga gatgttaaacggctgcagagtctcaacagagcctgggccactcactccgctcacctcact gagaggttcagtaaactgcaggcggtgttgctccaacagcagagtttcctccagaaatgt gaggtgtggatggagttcctgtctcagactgaacagaagctcgccgctgagatttcagga aactacctgaatctgctggagcagcagagagaccatgagttgttccaggcagagatgttt agcaggcaacagattctctactccatcatcaatgatggccatcatatgttggaccaagga caagtggatgacagagatgacttcagcgtgaagctggccttgttaggcaatcagtggcaa ggtgtagtgagacgggcccagcaacgaaggggcattattgatagcctggtccgtcagtgg cagaagtaccgggagatggcagagaagctgctacaatggcttcaagaagtgactcgtgat ccagatgaacatcagccaggagaaccagtcgccttgcagcaggccagaaacctattggat cagattcagctgagggagcgagtgctgcagaggcagcagggaggctacatcctgacggtg gaggccggcaggagccttctgctgacggccgatgccagggccgagtctaccctgcagacg gagctgatggacattcaggagaggtggaggcacgcccaccaccgtctggaccagcagaga agggagctgcacggcttgctcaagaactgggagcgatgtgaaaagggcataaatgcgtcc ctggagaagctgagggcctttaagaggaagctgtctctgctactgcctgaccaccatgag gagctccactcagagcaaatcagatgcaaggagttggaaagcagtgtggagggctggacc gatgacctcacttccttgttcctgctgagggacaccttggagggcgtggtcagtgcagat gacataacagtcctacaggaacgcctccagctgctacagcgccagtggggggaggtctgc caccagctttccctgcgcaggcagcaagtgagcgagaagttgaacgagtgggcagtgttc aatgagaaaaacaaggagctatgtgagtggctcacacagatggagagcaaggtctctcag aatggagacatcagcattgaagagatgatcgaaaagctgcgcaaggagtaccaggaggag atcggtgtagctcaggagaacaagcagcagctgcagatcatgggcgcgcgcctggccagg tccagccaagacggcaaggcggccgagatccaacacaaactcagcaaagttagcgagcgc tggcaacacctgctggacctcatcgccgccagggtgaagaagttgagggagacccttgtg gcggtgcagcagttggataaaaacatgagcagcctgcgttcgtggctcgctcacatcgag acggagctgtccaggcccatcgtctacgacacctgtgacgaccaggagattcagaggaaa ctcaaccagcagcaggagctgcagcgggacatagagaaacacagcacaggagtggcgtcg gtgttgaacctgtgtgaagtcctcctccacgactgtgacgcctgctccacagagacggag tgtgactccatccagcaagccaccagagggctggacaggcgctggaggaacatctgtgcc atgtccatggagaggaggctcaagattgaggagacgtggaggttgtggcagaggtttctg gatgattactccagatttgaagattggctgaagacctcagaaagaacagcagccctgccg aactcctccggagttctgtatactgtcgctaaagaagagctcaaaaagtttgaggccttc cagcgtcaggtgcaggagtgcctgacccagctggagctcatcaacaaacagtaccgtcgc ttggcccgggagaaccgcactgactcgtcctgccaactcagggaaatggtgcatgatggg aacaggcgatgggataacctgcagaggagggtggccgccatcctacgccgactcaagcac ttcatcagccagagggaggagtttgagacggcgcgagacattatcctggtgtggctgact gagatggacctccaactgaccaacatcgagcacttctctgagtgtgacgtacaggccaag ataaaacagctcagggctttccagcaggagatctatctgaacacagggaagattgagctg gtgttcagacagggtgacgctctgattgagaagagtgaacctctggacgcggccgtcatc gaggaggagctggaggagctgcagagatactgtcaggaggtttttggacgagtcgacaga tactacaagaaactcacacgactgcctctggccgacgatgagctcgatggttccgacagg gagctggacatggaggaaggtggcgagctctccgagctgcagtggggcgactcctctctg ccccggacgtccagccgtcagacctcgggtacaaccgccctcatccgggcagatcgctcg ggacgtgacaccccggccagcgtggactccatcccgttagagtgggaccacgactacgac ctgagcagaggtctggacagccctggaggacgaggccctggggaaaggagccacgggcaa gaggaaggagatgagtatctgaggacggctgtcacagtgctgtcagatgtagttatccca gagagcccagaggcctatataaaactgactgagaacacattgaaatcgtcctctggtgag gcgggccagctggaggccagtcttaggcagttggatcaggctctggatgcagggcaatac cacatccagcagagagaggccaccgtcaacagctccagccccgacgttgactccacatac atgggctatatgcgcctgatgggagagtgtcgaggcagtatagatgccgtgaagagagcg gagggagagctgactgaagatgaggacgacatgccaggactcaccaaccccaacagcaca gacactcaaagtgcaggtgtgatcgagcgctgggagctgatccaggctcagactctgagt gagaagcacaagcacaagcagaacctgcagcagtggcagcaactgatctcagatctgcag accatgcaggattggttgggtcagtctgaggctgaactcaaccagctacgagggctcgat ctcagcaccgacatacacaccatccagcagagaatcaagaggctcaaggagctgttgaaa ggggtggatgcccacaagtcagaggtcctgtccatcaatctgagcagtgcagagttcctc caatccgagtccgactccgaggaggcgtgggagttgagggacaggctgaaagagatgaac acacactgggatcggctcggtacctccctggaggactggagggaggagctacagagggcg cttatgcagtgccaggagttccatgagatgagccacggcctgctgctgtggctggagaac atcgaccgcaggaggaaccaggtggtgcccatcccgcccaaactggaccgcgaaacatta cgagctcatcacagaacactcacgaaaatcaagcgtgagctgctggactcgcagcagaag gtatcgtctcttcaggagctgtcagctcagctgctggtcaacaccaaacctctgacactg ctgctgcagtcgcaggccccggagcagagccaggctcagggcagcgagtgtctggaggcc caggagaaggtgcacgtgatcttgaaccggctgagactgctccttagggaggtcagctca gacctcgaggagctggagaggagactggagaccacgggcacacggcaggattgcttaccg ttgttgcctgttggcaaatcagaaatctgtggatcagctggtccagcgtcagaggtgact gtccaaagtcgcaagagatcgcctcgaggcaaaagtagtcaggcccacccaggacaccct aagagcggcccgcgccacagccggagcagatcaccaggcgccgctggctgcgtttcctcc cattctgaccttccggatggcgtctcctcatcgacctcctccgcctcctcaaaaggccag tccttcctgctgcgggtcctcagggctgcgcttcccgtccagctgctccttctgctcctg atcggcctggcctgcctggtgcccatgagccaggaggactacagctgccaccacgccaac aactttgcccgctccttccaccccatgttgcgttacaccaatggacctccgcccatatga

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