Cyclopterus lumpus (lumpfish): 117729144
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Entry
117729144 CDS
T09199
Symbol
pik3ca
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
clum
Cyclopterus lumpus (lumpfish)
Pathway
clum00562
Inositol phosphate metabolism
clum01100
Metabolic pathways
clum04012
ErbB signaling pathway
clum04068
FoxO signaling pathway
clum04070
Phosphatidylinositol signaling system
clum04081
Hormone signaling
clum04140
Autophagy - animal
clum04150
mTOR signaling pathway
clum04210
Apoptosis
clum04218
Cellular senescence
clum04370
VEGF signaling pathway
clum04510
Focal adhesion
clum04620
Toll-like receptor signaling pathway
clum04625
C-type lectin receptor signaling pathway
clum04810
Regulation of actin cytoskeleton
clum04910
Insulin signaling pathway
clum04914
Progesterone-mediated oocyte maturation
clum05100
Bacterial invasion of epithelial cells
clum05132
Salmonella infection
clum05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
clum00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
117729144 (pik3ca)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
117729144 (pik3ca)
04370 VEGF signaling pathway
117729144 (pik3ca)
04068 FoxO signaling pathway
117729144 (pik3ca)
04070 Phosphatidylinositol signaling system
117729144 (pik3ca)
04150 mTOR signaling pathway
117729144 (pik3ca)
09133 Signaling molecules and interaction
04081 Hormone signaling
117729144 (pik3ca)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
117729144 (pik3ca)
09143 Cell growth and death
04210 Apoptosis
117729144 (pik3ca)
04218 Cellular senescence
117729144 (pik3ca)
09144 Cellular community - eukaryotes
04510 Focal adhesion
117729144 (pik3ca)
09142 Cell motility
04810 Regulation of actin cytoskeleton
117729144 (pik3ca)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
117729144 (pik3ca)
04625 C-type lectin receptor signaling pathway
117729144 (pik3ca)
09152 Endocrine system
04910 Insulin signaling pathway
117729144 (pik3ca)
04914 Progesterone-mediated oocyte maturation
117729144 (pik3ca)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
117729144 (pik3ca)
09171 Infectious disease: bacterial
05132 Salmonella infection
117729144 (pik3ca)
05100 Bacterial invasion of epithelial cells
117729144 (pik3ca)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
clum04131
]
117729144 (pik3ca)
Enzymes [BR:
clum01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
117729144 (pik3ca)
Membrane trafficking [BR:
clum04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
117729144 (pik3ca)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI3Ka
PI3_PI4_kinase
PI3K_rbd
PI3K_C2
PI3K_p85B
DUF2321
ABC1
Ribosomal_S15
Motif
Other DBs
NCBI-GeneID:
117729144
NCBI-ProteinID:
XP_034385787
Ensembl:
ENSCLMG00005011927
LinkDB
All DBs
Position
4:5010955..5048821
Genome browser
AA seq
1068 aa
AA seq
DB search
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHQ
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGPHSRALYVYPPNVESTPELPKH
IYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDSVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLDRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYLNGEASAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPCAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHY
SSSVKYPDMNAVEDHANWTISRELGYNYNLSGQSNRSARDHALTESDTEQMRQLSNRDAL
SEITEQEKDFLWRHRHYCMIVPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRHFAVRCLDKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNYTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLRDKNKGEMYDLAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
NT seq
3207 nt
NT seq
+upstream
nt +downstream
nt
atgcctcccaggccatcatcaggagagctatggggcatccacttgatgcctcccaggatc
ctcgtggactgcctgcttcccaatggaatgattctgaccctcgagtgtctccgagaggcc
acgctcatcaccatcaagcatgagctgttcaaagaggccaggaaatatcccctccaccaa
ctcctacaggaggagacgtcctacatctttgtcagtgtgacacaggaagcagagcgggag
gagttctatgatgagaccagaagactatgtgacctccgactcttccaggccttcctcaag
gtcattgaaccagttggcaacagagaggaaaagatcctcaacagagagattggttttgcc
attggtatgcccgtgtgtgagtttgaccttgtgaaggatcccgaggtccaagacttcagg
agaaacatcctgaatgtttgtaaagactctgtggagctgagagacgccagcgggccccac
agcagagcgctgtatgtttatccaccgaatgtagaatccacaccggaacttcccaagcac
atctacagcaaactggacaaaggtcagattattgtggtgatttgggtgattgtttctcca
aacaatgacaaacaaaagtatacattgaagatcaaccacgatagtgtacctgaacaggtg
attgcagaggccattcgaaagaagacacgcagcatgctgctgtccccagagcagctaaag
atgtgtgttcaggaatatcagggtaaatacattctcaaagtgtgtggctgtgatgagtac
ctgctggaaaagtaccccatcagccagtataagtatatccggagttgcatcatgctcgac
aggatgccgaacctgatgctcatggctaaggacagcctatacactcagttgccaacggat
aactttgtcatgccgtcctactctcgccgcatctccacggcaacatcctatttgaatggc
gaggcatctgccaagtcgctgtggaccatcaatggaaccctgcgaatacgaatcctctgt
gccacctatgttaacgttaatatacgggacatagacaagatatatgtgagaacaggcatt
taccatggaggtgaacaaatgtgtgacaatgtcaacacacagagagtaccctgctctaac
cccaggtggaatgagtggctcacctatgatatgtacatcccagatataccctgcgctgca
agactctgcctctccatatgttctgtgaagggcaggaagggagccaaggaggagcactgc
ccactagcttggggtaatattaacttgtttgactacactcacactctggtggccaacaag
atggctctgaacctctggcctgtccctcatggcctggaggacctcctcaaccccattgga
gtcacagggtccaaccctaataaggaaaccccatgtctggagctggagtttgaccactat
agtagttcagtcaaatacccagatatgaatgcagtagaggatcacgcaaactggaccatc
tcgagggaactggggtataactacaacctctctggacagagcaatcgctcggccagagat
cacgctctgacagagagcgacaccgagcagatgagacagctgagtaacagagacgctctt
tcagaaatcactgagcaggagaaagacttcctctggagacacaggcactactgcatgatc
gtccctgagatccttcccaaaatcctcctcgctgtcaaatggaactccagagatgaagta
gcacagatgtattgtctgttaaaggaatggccgtctatccgccctgagcaggccatggag
ttgttggattgtaactatccagaccctatggtccggcactttgctgtacgctgccttgac
aaataccttactgatgacaaactgtcccagtacctcattcagcttgtacaggtattaaaa
tatgagcagtatcttgacaatcccctggcccgtttcctcctgaaaaaggccctgaccaat
caaaggataggtcatttcttcttctggcatctcaagtcagaaatgcacaacaaaacagtg
agccagaggtttgggctgctgttggaggcttactgcagggcatgtggcatgtacctcaaa
cacctgagcaggcaggtagaggccatggagaagctcattaacctcactgacatccttaaa
caggagaagaaggatgagacacagaaggtccagatgcggtttcttgtggaccagatgaag
agaccggactacatggatgctctgcagaactacacctctcctctcaaccctgcacaccaa
ctgggaaacctgaggttagatgaatgcaggatcatgtcatcagcaaagagaccgctgtgg
ctgaactgggagaatcctgacatcatgtctgagctgctctttcagaacaatgagatcatc
ttcaaaaatggagatgacttgcggcaggatatgctgacgttgcagatcattaaaatcatg
gagaacatttggcagaatcagggactggaccttcggatgctcccttatggctgtctgtcg
ttaggagactgtgtgggtctcattgaggtggttcgtagctcccacaccatcatgcagatt
cagtgtaaaggaggcttgaaaggagccctgcagttcaactcaaacactctgcatcagtgg
ctcagagacaagaataaaggcgagatgtatgacttggctgtggatctgtttacaaggtcc
tgtgctggctactgtgtagctacatttatccttgggataggagacagacacaacagcaac
attatggtcaaagatgatggacagttgtttcatatagactttggccatttcctggatcat
aagaaaaagaaatttggctacaagagagaacgagttccctttgtactgacgcaagacttc
ctcatcgtcatcagcaagggatcccaagagtgtgcaaagaccaaagagtttgagaggttc
caagagatgtgttataaagcctacctggcgatccggcagcatgctaacctcttcatcaac
ctgttctccatgatgctgggctctggcatgcctgagctgcagtcctttgatgacattgcc
tacattaggaagacattagccctggagaagagcgagcaggaggcgttggactattttatg
aaacagatgaacgatgcccaccatggaggatggaccaccaaaatggactggatattccac
acaattagacagcatgcacttaactga
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