Cyclopterus lumpus (lumpfish): 117731804
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Entry
117731804 CDS
T09199
Symbol
lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
clum
Cyclopterus lumpus (lumpfish)
Brite
KEGG Orthology (KO) [BR:
clum00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
clum01001
]
117731804 (lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
clum04131
]
117731804 (lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
clum04147
]
117731804 (lrrk2)
Enzymes [BR:
clum01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
117731804 (lrrk2)
Protein kinases [BR:
clum01001
]
Serine/threonine kinases: TKL group
LRRK family
117731804 (lrrk2)
Membrane trafficking [BR:
clum04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
117731804 (lrrk2)
Exosome [BR:
clum04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
117731804 (lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_4
LRR_8
Roc
COR
Ras
LRR_14
LRR_9
WDR55
LRR_NXF1-5
WD40_2
Beta-prop_RSE1_2nd
AAA_16
ARM_ARMC5
Ank_2
Beta-prop_EML_2
TFCD_C
NACHT
LRR_13
AAA_22
Septin
LRR_LRWD1
nSTAND3
UNC45-central
AAA_7
Viral_helicase1
DUF7079
cobW
Motif
Other DBs
NCBI-GeneID:
117731804
NCBI-ProteinID:
XP_034390118
Ensembl:
ENSCLMG00005012446
LinkDB
All DBs
Position
6:complement(4016913..4043168)
Genome browser
AA seq
2546 aa
AA seq
DB search
MVNQEELEERLKKLLVRLKIPQEDRQLCTLIQIVQDLLFLAHSDNAAELFEDKDVHAPLV
LVLSSYIGSREVQQVGWSLLCRLIEICPRTLDRLTRPLEAAKDWEVLGVHQQILKVLSQY
STDGRVTTVGLRALALLLRSDMIPLLVLEEEEDVFGLVVQAMKTFPASEEVQLQGCGALQ
LLLERVSDDHLVEFVENQDHVVVLAALQRFPDNPELLLQAMKVMLPLARPVSNVEMLMSG
GARCYSVVITATDAFPEVEDLQETACCLLRRFTSESYYNILVLNGVQRVAVRACRTFPDN
AALQAAALSCLADLTATIVHNKAVAEQGLEEGEEEENRGREEVEDMGLGWMEACCTALEL
HAAEPDVQEAASWAIHNLLLHGAAGNRSEEERDERTPVHRQLMVAMLLHSSSPSVFQAAT
SAIATLLTHNGEMRSLLLSSGLHVNLVEMMKRHPASPEVSINACKLLSLLFQGRTASLDE
LNMAMSQILGTMKVHNFQPEVQLEALQASLVFLCPDRSLREHGVSVADPDMADVSLKVLK
NQCVVEGAHTLYLEVLNRFISSSVIQTCGLRVLSALADCTGAVDLLCQQGAIDTVLHTLQ
MFPREREIHYWGFTLLTYLVSKKKLSRMIVPVLASVVVASLIQYGDDSEVLLKCFQVALR
MLDVCSGAAAELQREDFDRQIFRHLREETPDQNNCALRKPACLALSKMWCDSQLHYDMLE
KACEDGDAALAECLIELGADVNGKTKTESLIYQVCERGGPLELVELLLSRGAHEQHLRRA
LAVSVKRGEGPTVIQLLGRLGLDLNNSALCLGGFRLGRLDAAWLSPLLAERGRALTRRSN
SSKGVSLARYIQSFQRSKSVGGPPRPLGDPCLTSPCLTSGYISDESDDSSFSFASVDDGL
FFKDDAESDGSDSLSGVLSPKPHNKSLEELTAGSFNRKPGRRRHASAESGHIDTEHSEHV
QRRSGRTGSSQKVFGPGESSAPPCRERERILLLDLSGNELASPSCLLDDGFVRQQLGHLL
RLDLSHNGLLEFPSALCRSLRSLTRLDLQGNQLRSLPAELLSLLSLSTLNVSRNCVGPLL
TFDPAVACPSLRQLNLSFNRIAAFPHELGRAAAQLEELFLEGNGLTELCVPLRLPEIKLL
DVSNNSVEDISPDFLTGCPKLETFSASGNKICSLSHLPTKITTLKLSNNSFTDVPEAILH
LPNLRSVDMRTNRIAVLPGPGLWESSNLRELMFSQNAIRVLDLSGPIAKWTRLEKLHLSD
NKLARIPQQIGLLEGLTSLDVSRNANVRSFPDEMGKLGRLWDLPLDGLRLQLDLKLIGSK
TKDIVRFLQQRLKKAVPYYRVKLIVVGNAGSGKTALIQQLMKLKRSQAANNPKLAGVGID
VRDWTIKERDKKRMVLNVWDFSGGEEFSGSHPHFLTSRALYLVVYNLSKGAGQVDALKPW
LFNIKAVAPLSPVILVGTHTDVSDELQLQACLTKIREELLNHQGFPAIRDYHMVSVCEDS
DAMAKLRKAIAREVAGFKIQGQPVMGQLVPDSYVELERRVLQERTRAPPEFPVLRHRELL
QLIQESQLQLEEAELPHAVHFLSEAGVLLHFDDPALQLQELYFIDPQWLCNIISQKLTLK
SGGFWEPPKGVVQRSAVEKFLSETRCFPKSHLTQFFKLLEKFQIALPFGEDQLLVPSSLS
KHRPVIELPHCENSEVIVRLYEMPYFPLDYWSRQISRLLEVSSYLLCGREKAVRPNRIYW
RRGVYLSWSPEAYCLVEASSGEGNPSSFVRITVPSSRKGRVLLGQVVDHVDSLLEEWFPG
LLNTDVHGSGEALLKKWALYSFEDGQEWSKILLEDLFTCFDNDFLLVNPEDPRCTLPISQ
IAPDLVLSDQPAGTILDAEELHIDMSKENRLGDGGFGTVYRSVYKNEEVAVKLFNKHASE
LYIYRLLRQELVVLGRLRHPSLVSLLAAGISPPVLVMELALRGSLDFLFEHEHGGLNRKL
QHRIALQVADGLRYLHSAMIIYRDLKPHNVLLFNLKTDSEIIAKITDYGIAQHCCGMGVR
SSEGTPGFRAPEVARGNVTYNQQADVFSFGLLLYDLLTCGERISDGMKFPSEFDEAAVQR
KLPDPVKHYGCSPWPGFQVLMKDCLGESPQGRPTSAQVFDRLNSVEMLCLMRELPVPRVL
NGECLAVSAGGGGGGGGGVGPPNSLRAWLGGGSSAQRLGSITALDLDDGAVATQEIDSSP
VLCLVTVQIPSEACDWLVAGTQSGSLVVFSARDPTARHRLQSVADAVTSLYFHVHPRRTQ
RKNYLLVGSADGVLTVYEDSVLQQENGQPVKTLAVGHADTPVVCLGQSSHPLDSRSVWAG
CGAKILSFTADYDVCKSIDTRPSLVLQQQRSPGGEARVSQLVVDKYVYLSKAGTASVEVW
DKRGERMVDCIDCAQIIRGRKGGEAEPPGEARVKALLVQSAAALWVGTRGGHLLLLELST
HQALQVIGPCCDSVRCMASALIETLNWKNVVLVLGRRLPQDASQLDKESVLMVWNGTLPM
EVKDLNKHCEKREQMAVKMSERLQHD
NT seq
7641 nt
NT seq
+upstream
nt +downstream
nt
atggtgaaccaagaggagctggaggagaggctgaagaagctcctggtgaggctgaaaatc
ccgcaggaggaccgccagctgtgcacgctgatccagatcgtccaggatctgcttttcctc
gcgcactcggacaacgcagccgaactgtttgaggacaaagatgtccatgcccccctcgtg
ttggtgctgtcatcctacatcggcagtagagaagtccagcaggtgggctggtcgttgctc
tgccggctgattgaaatatgcccccgcacgctggaccggctgaccagacctctggaggcc
gccaaggactgggaggtactgggagtgcaccagcagatcctgaaggtgctctctcagtac
agcacggacggccgagtcaccacggtcggactccgggccctggccctgctgctcagatca
gacatgattcctctgctggtgctggaggaggaagaggatgtgtttggcctggtggtgcag
gcgatgaagacgtttcctgccagtgaagaggtgcagctccaaggctgtggagccctgcag
ctcctgttggagagagtgagtgacgaccacctggtggagttcgtggagaaccaggaccac
gtcgtggttctggcggctctgcagaggttcccggacaacccggagctgctcctgcaggcc
atgaaggtgatgctgccactggctcgtcccgtgagtaacgtggagatgttgatgtcgggc
ggcgctcggtgctacagcgtcgtcatcaccgccacggacgccttccccgaggtggaggac
ctgcaggagacggcctgctgcctgttgaggaggtttacgtcagagagttactacaacatc
ctggtgctgaacggcgtccagagggtggctgtccgagcctgccggactttcccggacaac
gccgcgctgcaagccgccgctctctcctgtctggctgacctcaccgccaccatcgtgcac
aacaaagcggtggccgagcagggcctggaggagggcgaggaggaggagaacaggggccgc
gaggaggtggaggacatgggcctgggctggatggaggcctgctgcacggcgctggagctc
cacgcggccgagcccgacgttcaggaagcagcgagctgggccattcacaacctgttactg
cacggagctgcagggaaccgctcggaggaggagcgggacgagaggactcccgttcacaga
cagttgatggtggccatgctgctccactcctcctctcccagtgtgtttcaagccgctacc
agtgccatcgccacactcctcacgcacaacggtgagatgcgctccctgctgctgtccagc
ggcctccacgtcaacctggtggagatgatgaagagacacccggcctcgccggaggtttcc
atcaacgcctgcaaactgctcagcctgctctttcagggaaggacagccagtctggatgag
ttgaacatggccatgagtcagatcctcggcaccatgaaggtccacaacttccagccagag
gttcagctggaggctctgcaagccagcctggtcttcctctgcccagaccggagtttgagg
gagcacggcgtctcggtggcggaccccgacatggccgacgtgtcgctgaaggtcctgaag
aaccagtgcgtggtggaaggagcccacaccctctacctggaggttctcaacaggttcatc
agcagctccgtcatccagacgtgcggcctgagggtgctgtctgctctggccgactgcacc
ggtgcggtggacttgctctgccagcagggggcgatagacacggtgctgcacacactacag
atgttcccacgggaacgagagatacactactggggcttcaccctgctcacctacctcgtg
tccaagaagaagctgtcgcggatgatcgtacccgttctggcctcggtcgtggtcgcctcc
ctcatccagtacggagacgactccgaggtgctgctgaagtgttttcaggtggctctgagg
atgctggacgtctgttcaggagcagccgctgagctgcagagggaagactttgacaggcag
atcttcagacacctcagagaggagaccccggaccagaacaactgtgctctgcgtaagccg
gcctgcctggctctgtctaagatgtggtgcgactcccagctgcactacgacatgctggaa
aaggcgtgcgaggacggagacgccgcgctggccgagtgtctgatcgagctgggcgccgac
gtcaacgggaagaccaagacggagtctctcatctaccaggtgtgtgagcgaggcggaccc
ctcgaactggtggagctcctcctcagccggggcgcccacgagcagcacctgcgcagggct
ctggccgtgagcgtgaagcgcggcgaggggcccacggtcatccagctgctgggccgcctg
ggcctggacctcaacaacagcgccctctgcctcgggggcttcaggctcggccgcctggac
gccgcctggctcagccccctgctggcggagagaggccgcgcgctcacccgccgctccaac
agcagtaaaggtgtgagcttggcgaggtacattcagtcgttccagaggtccaagagcgtc
ggcggtcctccgagaccgctgggcgacccctgtctgacctccccctgtctgacctccggc
tacatctccgacgagagcgacgactccagcttcagcttcgcctccgtggacgacggcctg
ttcttcaaagacgacgcggagagcgacggaagtgactctttgtcgggcgttctgtctcca
aagccgcacaataaatcgttggaggagttgacggcggggtccttcaacaggaagccgggg
cgccgcagacatgccagcgcagagagtggtcacattgacactgaacacagtgagcatgtc
cagaggagaagtggacggaccggctccagtcaaaaagtgttcgggcccggcgagagctcc
gcccctccgtgccgagagagagagcggatcctcctgctggacctgtcgggtaacgagctg
gcctccccgtcctgcctgctggacgacggcttcgtccggcagcagctgggtcacctcctc
cgcctggacctgagccacaacggcctgctggagttcccctcggctctctgccggagtttg
aggagtctgacccgactggacctgcagggcaaccagctgcggtcgctgcccgcggagctg
ctgtctctgctctcgctgagcacgctcaacgtgtcccgcaactgcgtgggacccctgctg
acctttgaccccgccgtcgcctgcccgtcgctgcggcagctcaacctgtcgttcaaccga
atcgccgcgttcccccacgagctcggccgcgccgcggctcagctggaggagctgttcctg
gaagggaacggtttaacggagctctgcgtgccgctgcgtctgccggagatcaagctgctg
gacgtgagcaacaacagcgtggaggacatctctccggacttcctgaccggctgccccaaa
ctggaaaccttcagcgcctccggcaacaaaatatgttcactgtcgcacctcccgaccaag
atcacaacgctaaaactgtcaaacaacagcttcaccgacgtccccgaggccatacttcac
ctcccaaacttgcgctcggtggacatgagaaccaaccgcatcgctgttctgcccggcccg
ggactctgggagtccagcaacctccgagagctgatgttcagccagaacgccatcagggtt
ctggacctgagtgggccgatcgccaagtggacccgactggagaagctccacctgagcgac
aacaagctcgctcggatcccccagcagatcggcctgttggaaggactcacctcgctggac
gtgagtcgtaacgccaacgtgcgctccttccccgacgagatggggaagctgggccgcctg
tgggacctcccgctggacggcctccgactccagctggacctcaagctcatcggcagcaag
accaaagacatcgtcaggttcctgcagcagcggctgaagaaggcggtgccgtactaccgc
gtgaagctcatcgtggtggggaacgccggcagcgggaagaccgccctgatccagcagctg
atgaagctgaagcgctcccaggcggcgaacaaccccaagctggccggcgtcggcatcgac
gtccgggactggaccatcaaggagcgggacaagaagaggatggtgctgaacgtctgggac
ttctcaggaggagaggagttcagcggctctcaccctcacttcctgacctccagagctctc
tacctcgtggtgtacaacctcagcaaaggagccggtcaggtggacgccctgaagccctgg
ctcttcaacatcaaagccgtcgcccccctgtccccggtcatcctggtgggaacccacacg
gacgtgagcgacgagctgcagctccaggcctgcctgaccaagatccgggaggagctgctg
aaccaccagggcttcccggccatcagggactaccacatggtctcggtctgcgaggactcg
gacgccatggccaagctgcgcaaggccatcgccagggaagtcgccggcttcaagatccag
ggccagcccgtgatgggccagctggttccggacagctacgtggagctggagcgccgggtt
ctgcaggagaggaccagggctccccccgagttccccgtgctgaggcaccgggagctgctg
cagctcatccaggagagtcagctgcagctggaggaggcggagcttccccacgccgtccac
ttcctcagtgaagccggggttttactgcactttgatgaccctgctcttcagctccaggag
ctctacttcatcgacccccagtggctgtgcaacatcatctcccagaaactgacgttgaag
agcggcggcttctgggagcccccgaaaggagtcgttcagcgctcggcggtggagaagttc
ctgtctgagacccgatgtttccccaagagccacctgacgcagttcttcaaactgctggag
aagtttcagatcgctctgcccttcggcgaggaccagctgctggtgcccagcagtttgtcc
aaacaccggccggtgatcgagctgcctcactgcgagaactccgaggtgatcgtgcgcctg
tacgagatgccgtacttccccctggactactggtctcgccagatcagccgcctgctggag
gtctcgtcttacctgctttgcggaagagaaaaagcggtgcgacccaaccggatctactgg
aggaggggcgtgtacctgagctggtccccggaggcctactgtctggtggaggcctcctcg
ggggaggggaacccctccagcttcgtcaggataactgtgccctcctcgcgcaaaggccgg
gtgctgctgggtcaggtggtggaccacgtcgactccctgctggaggagtggtttcccggc
ctgctgaacaccgacgtgcacggcagtggcgaggctctgctgaagaagtgggccctctac
agcttcgaggacgggcaggagtggagcaagatcctgctcgaggacctcttcacctgtttc
gacaacgatttcctgctggtgaacccggaggacccccgctgcacacttcccatctctcag
atcgcccccgacttggtgctgagtgaccagccggcggggacgatactggacgccgaagag
cttcacatcgacatgtcgaaggagaaccgactgggggacgggggctttgggacggtctat
cgaagcgtctacaaaaacgaagaagtggccgtgaagttattcaacaagcatgcgtctgag
ctttacatctacaggctcctcagacaggagctcgtggtgctgggtcgcctccgtcacccc
agcctggtcagcctgctggcggccggcatttctcctccggtcctggtgatggagctggct
ctgagaggctcgctggacttcctgtttgagcacgagcacggcggcctcaacaggaagctg
cagcacaggatcgccctgcaggtggccgacggactcaggtacctccactcggccatgatc
atctaccgggacctcaagccccacaacgtcctgctcttcaacctgaagaccgactccgag
atcatcgccaagatcaccgactacggcatcgctcagcactgctgcggcatgggcgtgagg
agctcggagggcacgccgggtttccgagccccggaggtcgcccggggcaacgtgacctac
aaccagcaggccgacgtgttctccttcggcctgctgctctacgacctcctgacctgcggc
gagcgaatctccgacggcatgaagttccccagcgagttcgacgaggccgcggtgcagagg
aagctgccagacccggtgaaacactacggctgctcaccgtggccgggcttccaggtgctg
atgaaggactgtttgggggaaagccctcagggtcgacccacctctgctcaggtgttcgac
cggctgaactccgtggagatgttgtgcctgatgagggagttgccggttccccgggtgttg
aacggcgagtgcctcgcggtgagcgccggcggtggcggcggtggcggcggtggcgtcggc
cccccgaacagcctccgagcctggctgggtggaggcagcagcgcccagagactcggctcc
atcacggcgttggacctggacgacggcgccgtcgccacgcaggaaatagactccagtccc
gtcttgtgtctcgtgaccgtccaaatcccgagcgaggcgtgcgattggctggtggcgggc
acccagtccggctccttggtggtcttcagcgctcgggacccgacggctcggcaccgcctg
cagagcgtcgcggacgccgtcacctcgctgtacttccacgtgcaccctcgtcgcacccag
agaaagaattacttgcttgtcgggtcagccgacggagtgctcaccgtttacgaagactct
gttctccagcaggagaacgggcagccggtcaaaacgctggcggtgggccacgccgacacg
cccgtcgtgtgcctgggccagtcgtcccatccgctggacagcaggtcggtgtgggccggc
tgcggcgccaagatcctctccttcaccgccgactacgacgtctgcaagagcatcgacacc
aggcccagcctcgtcctgcagcagcagcggtcgccgggaggagaagcgcgtgtgtcgcag
ctcgtcgtggacaaatatgtttacctgagcaaagccgggaccgcaagcgtcgaggtctgg
gacaagaggggcgagaggatggtggactgcatcgactgcgctcagatcatcagaggcagg
aagggcggtgaggcggagccgcccggcgaggcccgagtgaaggcgctgctggtgcagagc
gccgcagctctctgggtcggcactagagggggccacctgctgctgctggagctctccaca
caccaggcgctgcaggtcatcggcccctgctgcgactccgtccgctgcatggcctctgcg
ctcatagaaacactaaactggaagaacgtggttctggttctgggcagaagactcccgcag
gacgccagtcagctcgacaaggagtctgtgctgatggtgtggaacggcacgctgccgatg
gaggtcaaggacctgaacaagcactgcgagaagagggagcaaatggcggtcaaaatgagc
gagcggctccagcacgactga
DBGET
integrated database retrieval system
