KEGG   Cyclopterus lumpus (lumpfish): 117741125
Entry
117741125         CDS       T09199                                 
Symbol
pik3cb
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
clum  Cyclopterus lumpus (lumpfish)
Pathway
clum00562  Inositol phosphate metabolism
clum01100  Metabolic pathways
clum04012  ErbB signaling pathway
clum04068  FoxO signaling pathway
clum04070  Phosphatidylinositol signaling system
clum04081  Hormone signaling
clum04140  Autophagy - animal
clum04150  mTOR signaling pathway
clum04210  Apoptosis
clum04218  Cellular senescence
clum04370  VEGF signaling pathway
clum04510  Focal adhesion
clum04620  Toll-like receptor signaling pathway
clum04625  C-type lectin receptor signaling pathway
clum04810  Regulation of actin cytoskeleton
clum04910  Insulin signaling pathway
clum04914  Progesterone-mediated oocyte maturation
clum05100  Bacterial invasion of epithelial cells
clum05132  Salmonella infection
clum05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:clum00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    117741125 (pik3cb)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    117741125 (pik3cb)
   04370 VEGF signaling pathway
    117741125 (pik3cb)
   04068 FoxO signaling pathway
    117741125 (pik3cb)
   04070 Phosphatidylinositol signaling system
    117741125 (pik3cb)
   04150 mTOR signaling pathway
    117741125 (pik3cb)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    117741125 (pik3cb)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    117741125 (pik3cb)
  09143 Cell growth and death
   04210 Apoptosis
    117741125 (pik3cb)
   04218 Cellular senescence
    117741125 (pik3cb)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    117741125 (pik3cb)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    117741125 (pik3cb)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    117741125 (pik3cb)
   04625 C-type lectin receptor signaling pathway
    117741125 (pik3cb)
  09152 Endocrine system
   04910 Insulin signaling pathway
    117741125 (pik3cb)
   04914 Progesterone-mediated oocyte maturation
    117741125 (pik3cb)
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    117741125 (pik3cb)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    117741125 (pik3cb)
   05100 Bacterial invasion of epithelial cells
    117741125 (pik3cb)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:clum04131]
    117741125 (pik3cb)
Enzymes [BR:clum01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     117741125 (pik3cb)
Membrane trafficking [BR:clum04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    117741125 (pik3cb)
SSDB
Motif
Pfam: PI3_PI4_kinase PI3Ka PI3K_p85B PI3K_rbd PI3K_C2 RWD
Other DBs
NCBI-GeneID: 117741125
NCBI-ProteinID: XP_034403803
Ensembl: ENSCLMG00005008841
LinkDB
Position
13:complement(17917826..17953272)
AA seq 1080 aa
MPPAMTDLLDIWAAHSHLAGHALDKITVDFLLPTGIYIQMDVPREATIQHIKLLLWKQAQ
SFPLFPSLGEMESHMFECVNQAAVHEELEDETRRLCDIRPFLPVLKLVTRNCGRAERLLD
SKIGVLISKGLHELDAINDQEVKDFRSKMFRLSEERMQQVQMMTCTEWLQACFSPQLEPP
AGTAITDGLNDRPADLKIIIHFDQSQDSASLKVPSSCVPSELMELALKKWLTTHGPEEEE
AWRGQYVLRVSHCLEFLCGDQPLIQYKYIRTCMQAKESPRLTLVHTSTVKAMFDKEISTI
GAVVGRKSSNPPLPLPPKRRVPTQVQTCVWDVSSSFKIVLVNGSKVNAEETAKVQVRAGL
FHGTELLCKPAVSSESSGRSDHTWKDSTLEFDLSVCDLPRMTRLCFAIYAVMDKVKKQKS
TKNAHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDIILHCWSSFPDELEEMLNPI
GTIQTNPYTENATSLHINFPEYSSHSIVFPPFDKILEKAAEIARASDCVSMGRGGKKFHI
ELKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQ
IWPKLSPRDALELLDFNYPDQYVREYAVGCLRDMSEEELSQYLLQLVQVLRYEPYYDCAL
THFLLERAQGNRKIGHFLFWHLRSEIHMPAVSVQFALILEAYCRGSIPHIEVLKKQVEAL
SKLKSVNELIKLGTIKTARSKTKEAMLTKEAMMTCLRQSGYSETLSDLHSPLNPNVLLSG
INVERCRYMDSKMKPLWIVYNNKLLGGDTLGIIFKNGDDLRQDMLTLQILRLMDLLWKEA
NLDLRIVPYGCLATGDRSGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERNS
GDALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFG
IKRERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLVLRKNGNLFITLFALMLTA
GLPELTSVKDIQYLKDSLALGKTDEDALKQFRQKFDEALRESWTTKVNWMAHNVAKDNRS
NT seq 3243 nt   +upstreamnt  +downstreamnt
atgcctcctgccatgacagacctcctggacatatgggcggcccactcgcacctggccggc
cacgctctggacaagatcaccgtggacttcctgctgcccaccggcatctacatccagatg
gacgttccgcgcgaggccaccattcagcacatcaaactgctcttatggaagcaggctcag
tcgttcccactgttcccctccctgggcgagatggagagccacatgttcgagtgcgtcaac
caggccgccgtgcacgaagaactggaggacgaaacgcgccggctgtgcgacattcgccct
ttcctgccggtcctcaagcttgtgacgcgcaactgcggccgagcggagcgcctgctggac
tccaaaatcggcgtgctcatcagcaaggggctccatgaactcgatgccatcaacgaccag
gaggtgaaggacttccgcagcaagatgtttcgcctcagtgaagagaggatgcaacaagtc
cagatgatgacgtgcacggagtggctgcaggcctgcttctccccgcagctggagcccccg
gcggggacggccatcaccgacgggctcaacgaccggccggccgacctgaagatcatcatc
cacttcgaccagtctcaggactcggccagtctgaaggtgccgtcgtcctgcgtcccctct
gagctgatggagctggccctgaagaagtggctgaccacccacgggcccgaggaggaggag
gcgtggcggggtcagtacgtgctgagggtcagccactgcctggagttcctgtgcggagac
cagcccctgatccagtacaagtacatccgcacgtgcatgcaggccaaggagtccccgcgc
ctcaccctggtccacaccagcaccgtcaaggccatgttcgacaaggagatctccaccatc
ggcgctgtggtcggacgcaagtcctccaacccgcctttaccgctacctcccaagagaaga
gttcccacgcaagtacagacgtgtgtgtgggacgtgtccagctcgtttaagatagtcctt
gtgaacggcagcaaggtgaacgccgaggagacggccaaggtccaggtgagggcggggctc
ttccacggcacggagctgctctgcaagccggcggtgagcagcgagagcagcggccgctcg
gaccacacgtggaaagacagcacgctggagttcgacctctccgtctgcgacctgccgcgc
atgacccgcctctgcttcgccatctacgccgtcatggataaggtcaagaagcagaagtcc
accaaaaacgcccacataaacaagtaccagaccatccgcaaagccgggaaagtgcactac
ccgatagcttgggtcaacacgatggtgtttgactacaaaggccagctgaagaccggggac
atcatcctgcactgctggtcttccttccctgatgaacttgaagagatgctgaaccccata
ggaaccattcagaccaacccgtacacggagaacgccacgtcgctccacatcaacttcccg
gagtactcgtcgcactccatcgtcttccctcccttcgacaagatattggagaaagctgca
gagatcgccagagcaagtgactgcgtatccatgggtcgcggggggaagaagttccacatc
gagctgaaggagatcatggagcgcgacccgctctctcagctgtgtgagaacgagaaggac
ttgatttggacgcttcgctacgactgcagggagaacttcccccagtcgctgcccaagctg
ctgctctccgtcaagtggagcaaacacgaggacatggcccagctccaggcgctgcttcag
atctggcccaaactgagtcccagagacgctctggagcttctggactttaactaccctgac
cagtatgtcagagagtatgcggtgggctgtctgcgtgatatgagtgaggaggagctgtcg
cagtacttgctacagttggtgcaggtgttgcgctacgagccctactacgactgcgccctc
acacacttcctgctggagcgagcccaggggaaccgcaagataggacacttcctcttctgg
cacttgcggtcggagatccacatgccggctgtttcagtccagttcgccctcatcctggag
gcctactgcagaggcagcatccctcatattgaggttctaaagaaacaggtggaagccctg
agcaagctgaagtcggtgaacgagctcatcaagctggggaccatcaagaccgctcggagt
aagaccaaggaggccatgttgaccaaagaggccatgatgacttgtctgaggcagagcggc
tactcggagacgctgtcggaccttcactcccctctgaaccccaacgtgctgctgtccggc
atcaacgtggagaggtgtcggtacatggactctaagatgaagccactctggattgtttac
aacaacaagctgctgggcggagacaccctgggaatcatcttcaagaatggagatgacctg
aggcaagacatgttgaccctccagattctgaggctgatggatctgctatggaaggaggcg
aatctggatctcagaatcgtaccgtacggttgcctagcgacgggtgaccgctcggggctg
atcgaggtggtctcgtcggccgacacgatcgccaacatccagctgaccagcagcaacgtg
gcggcggcggccgccttcaacaaggacgcccttctgaactggctcaaagagaggaactct
ggggatgctcttgagcgagccatcgaggagttcactctgtcatgtgcaggctactgtgta
gccacctacgtcctgggcatcggagaccgccacagcgacaacatcatggtccgcagcacc
ggacagctcttccacatcgacttcggccacatcctgggcaacttcaagtccaagttcggc
atcaagagggagcgggtgccattcatcctcacgcacgacttcatccacgtcatacagcag
ggcaagaccggatacaccgagaaatttggcagtttccgtcagtactgtgaggaagcctat
ctggtcttgaggaagaacgggaacctcttcatcaccctgtttgccctcatgctgaccgcc
ggcctgcctgagctcacctccgtcaaagacatccagtacttaaaggactctctggctttg
ggtaaaaccgacgaggatgcgctgaagcagttccgccagaagttcgacgaggccctgaga
gagagctggacaaccaaagtcaactggatggcccacaatgtggccaaagacaaccgctcc
tag

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