Cyclopterus lumpus (lumpfish): 117741230
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Entry
117741230 CDS
T09199
Symbol
brca2
Name
(RefSeq) breast cancer type 2 susceptibility protein isoform X1
KO
K08775
breast cancer 2 susceptibility protein
Organism
clum
Cyclopterus lumpus (lumpfish)
Pathway
clum03440
Homologous recombination
clum03460
Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:
clum00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
117741230 (brca2)
03460 Fanconi anemia pathway
117741230 (brca2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
clum04121
]
117741230 (brca2)
03036 Chromosome and associated proteins [BR:
clum03036
]
117741230 (brca2)
03400 DNA repair and recombination proteins [BR:
clum03400
]
117741230 (brca2)
Ubiquitin system [BR:
clum04121
]
Ubiquitin ligases (E3)
Multi subunit type E3
BRCC complex
117741230 (brca2)
Chromosome and associated proteins [BR:
clum03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Other centrosome duplication proteins
117741230 (brca2)
DNA repair and recombination proteins [BR:
clum03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA complex
117741230 (brca2)
FA (Fanconi anemia) pathway
Downstream FA components
117741230 (brca2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCA-2_helical
BRCA2
BRCA-2_OB1
BRCA2DBD_OB2
Tower
Motif
Other DBs
NCBI-GeneID:
117741230
NCBI-ProteinID:
XP_034404003
LinkDB
All DBs
Position
13:9578217..9592212
Genome browser
AA seq
2744 aa
AA seq
DB search
MDLTSKNMYETYKDGIWKALGPLDPDWFEALTSQMFAEGNVSDQDDLCGNQEANFKAPLD
KTAVDSQLFSTPKVFRQHRVVSPETEEEQSFTDKETLPWTTTESPCLFQMSKEGIPGANN
GGFHQDRFDMLHTPHKYPFSYDKKISESLGAQLHPDMSWTSSLNTPPAVPSTLILSKSDE
SPCPVSLSADKNVVFVRKLFPSLSNASRVGVVSLKNKDVTTVHQGVGSPEAVQHLESHDS
PQSSLNQSDLVWKQTLPDAIEDGEIRRTVAGVLDGAEHVLSIFFTNSSSALRKVKTDRIK
RKHSFLTEDGCSSVDVTLTNNAASSDQRTVDQEPGRLPSPPPVKTVDSGITQWSPLSLSE
LPSYTVNSSCHNNSLAVQVENTISTEQLHHDSDTGQLIVRPRMRHTDSGFTKKKRTFVYT
VETPKLQVQGKETECRRMDSSPVPDSGQEVKVKQLKAQDEADRCSVGTNEGKQGNLVDVN
LRPSVQPKVQDLDMSQLCKDFEQDFSQMSDPCKLSKVAEDTPGIGFSPSTCLSAVKRAKQ
KAMQANRHHYDGISDRRQVSTAHQNNPINEGTISDSGFQSAVADSANGTAPSFVLPSSEM
NGLQLTDKQRATPATSINKGNGKAFLDDILQVSKTDAKWSSAIGESQTLGPGRESELHRE
STSAQRPSSAKEAVDNINCLSLNGQACGNLPEKTVSHPSRFTTASNKGIHISSSNLERAK
HLFAETEGERTSSDQRTKCAHDTKVERRVSHGSMKNPTTNSNQSFPLSETNEDMRCQLTV
SQKADVTELCTLLEEADSQFEFTQFKTEMPKQNCQDNAASPLKVHKELDPEFLSGINFDD
SFSSEAEKHLAAIVKPDKMTSISDGKTNCETTDGTHISTGLSLSSAVKKENSSPEESSTS
SKHISEGSSSVMSAEPKNLDGVGHELQNKIPLMLGVGFKTAGGNVLRVSKKCLSKAKALF
AGLEENVVTSQTSPDKQSSKTDTKRQFRRSVDNPTNNFLHHKEDHSSFTACGDDTEGQGQ
AYFSNTNRQVTCIRDGEAAKSLINCKRDTAACQSGFQMASGKGISVSAKAMQEAEALFGD
CDAIDSNACKRSIEALSGSVSHEESLPKCEVQGMKVNWSKEPLGEFENVNAGPAARQTEV
VQHNEETHNLGFTKTTRTNDAFFRGNPYSPATALSSLSCTSSKNIGSSANHELSNGGGFC
SASGNKALMSADALKKGEHLLNELPTPGDANKQHKRKGDALRSVHLCNPIQVSPPKSGGF
QTASGKGVAISSTALKKAKMLLIECDEVENTIFVKPTLSEMPVPGPTPRNSGFLAASGKR
VAFSSEVLQKAKALFSDIRFNAEIPTVTDTRDSGKTQDEAEVTEKIHCGFTTAGGAKVHV
SKKNLLEAKNLLTEFDDSSISAEAMQEADAYFKDCDIMDDNNGMSVKQKKGIAPGCGRGS
EKKNLLRCKVDQRLKINISEELARGHAEFENVSMGLVENHERMLHPDVEIHKGAFKKTLD
VSNAAALHGNPSLMTKTPPPLSCTTSKNISSPTMNELSKGFSTASGKKVSVSDDAMTKAK
SLLNESATFEDSNKPLKHKESTFPTQNGGFQTASGNGVAISSAALKKAKTLFSECDEVEN
TIFVKPTHSKMPVPGPTPRNSGFLAASGKRVAFSSEALQKAKALFSDIRFNAEIPAVTDT
RDSGKTQDEAEVTEKIHCGFTTAGGAKVHVSKKNLLEAKNLLTEFAECHDSNSTIPHDIC
KSDPSIVKGVKTPCNPTTGGDMDMFSAPWVVENESPQSQSVPRCISIEDQAHADAFSVKE
GQMTPAVSGNLHDGLVSRVLDYKIQQTSSREGSKVKRPQMSSVLNFQSLNLSGCTETQQK
LFAQEALDCTKALLEDEGLAGQSLSMTLENASHRSVAKRQGTEKRLIEDPDMAGQPPLKR
RLLEEFDRTVHGPRSSTLHPEKSCPNGVMKDRRIFKYSVSLHPNITRPHANGKMYVETRL
QDTTPTQYSTPEENRSAHSGKPAFVPPFLTNTKTESRRNTMLKDNIRTPSAFVPPFKKQR
PFVRESSAKPQVEEKEDKHHHLFVMPFNRNPYVPPTHKKQSTSELTADKSKEDIETVALA
HNTNDNLINSKNLPVGCGSEGSAAETSHMEDTLSRSQDIFQNLHNVELARDMQDMRIRKK
KRLTIRPFPGSLFLTKSSGATRIPLKAAVNGRPPARYTPKQLYGHGVHQHVCEISSETAE
SFRFHLKQFIKQEAFLDGGGVQLADGGWLIPSKDGTAGKEEFLRALCDTPGVDPKLISEA
WVYNHYRWVVWKQASMERSFPETMGGLCLTPEQVLLQLKYRYDVEVDHSRRPALRKITEK
DDTAAKTLVLCVCGVVSRGHSPNRQSFNDTKTPQGADAKVESPSAVVWLTDGWYAIKAQL
DEPLTAMLHTGRVAVGGKLIIHGAQLVGSQEACPPLEAPESLMLKICTNSSRPTRWNTKL
GFHRDPRPFLLPVSCLYSSGGPVGCVDIIVLRSYPLQWMERKPDAGVVFRSVRAEEKEAR
RYNCHKQKAMEILFAKIQDAFEKEDKGDNKPQRRRRTVSRQGIASLQAGEELYEAVGDDP
AYLEAHLSEQQLETLGTYRRSLMEKRQAELQDRYRRALESAEDSEGSCPKRDVTPVWRLC
VADSMDQHGSVYQLNLWRPSSDLQSLLKEGCRYKVYNLTTSDGKKHGGGTAVQLTGSKKP
SFRSYRLLRNGYQHVFDRGSLPVLWIFKTQNSSRCVEKLISQDM
NT seq
8235 nt
NT seq
+upstream
nt +downstream
nt
atggatttgacctctaaaaacatgtacgagacatataaagatggcatctggaaagcgctg
ggacccttggatcccgactggtttgaggcactgacatctcaaatgttcgctgagggaaat
gtctctgatcaagatgacctgtgtgggaaccaagaggcaaactttaaagcacctcttgac
aaaactgcagtagacagtcagctgttctcaacccccaaagtcttcaggcagcatcgagtt
gtgtcacctgaaactgaggaggagcagtcgttcactgacaaagaaacattgccatggacg
accaccgaaagtccatgcttgttccagatgtcaaaagagggaatcccaggtgcaaataac
ggaggtttccatcaggaccgttttgatatgcttcacaccccacacaaatacccattcagc
tatgacaagaaaatatctgaaagtctcggagcccagcttcatcctgatatgtcatggacc
agttctctgaataccccaccagccgtaccatccaccctaattttgtctaaaagtgacgag
agtccctgtccagtgagtctttctgcagacaaaaatgttgtgtttgtacggaagctgttc
ccctctctttcaaatgcatccagagttggagtggtgtcactcaaaaacaaagacgtaact
accgtccaccaaggcgttggttcccctgaggcggttcagcatctagagtcccacgactcc
ccccagagttccctgaatcagagtgaccttgtttggaaacagacactaccagatgctatt
gaggatggagaaattcgcagaacagtagcaggtgttcttgatggagctgaacatgttctc
tctatatttttcaccaacagtagctcagcgctgaggaaagtgaaaactgacagaatcaaa
agaaagcatagctttttaacagaagatggctgcagctctgtggacgtcacattaacaaac
aatgctgcatccagtgaccagagaacagttgatcaggaacctggcaggcttccctcaccc
ccaccggtgaaaactgtagatagtggaatcacccagtggtctccgttgagtttatctgaa
ctcccatcttatactgtgaattcttcttgccataataatagtcttgctgtacaagtagaa
aacactatttcaacagaacaactgcaccatgactctgacactggccagctaatagtcagg
ccacgtatgagacacacagactctggatttaccaagaaaaagagaacatttgtttacact
gttgagaccccaaaactgcaagttcaaggaaaagaaacagagtgtcggaggatggactca
tcaccagttccagattctggacaagaagttaaagtgaagcagttgaaagcccaagatgaa
gcagaccgttgcagtgtcgggacgaatgaggggaaacagggaaatcttgttgacgtaaat
ctgcgtccttctgtacaaccaaaagtccaggatcttgacatgtcgcagctttgcaaagat
tttgagcaagatttcagtcaaatgtccgacccctgtaaactgagtaaagtagcagaggat
actcctggaatcggcttctctccgtcaacttgtctgtcagccgtgaaacgagctaagcag
aaagcaatgcaagcaaaccgtcaccattacgatggcatcagtgacagaagacaggtttct
accgctcatcaaaataacccaatcaatgagggaacaataagtgacagtggattccagtct
gctgttgcagatagcgctaatgggactgcaccatcgtttgttctccccagctcagagatg
aatggtctacagttgaccgataaacaaagagccactcctgccacatctataaataaaggg
aatggaaaagcctttttggatgatattttacaagtatccaaaacagatgccaagtggtcc
agtgcaatcggggaaagccagacactgggccctggcagggagagtgagctgcacagagag
agcacatcagcacaacggcccagcagtgcaaaagaagctgtggataacattaattgcctt
tcacttaatggtcaagcttgtggcaatctgccagagaagacagtatcgcatccttcaaga
ttcacaaccgcttcaaataagggtatacacatttcttcatccaacctggaaagagcaaaa
catctctttgctgagactgaaggggaaagaacttccagtgaccagcgcaccaaatgtgcc
cacgatactaaagttgaaaggcgtgtgagtcatggatcaatgaaaaatccaaccactaac
tcaaaccagtcatttcctttgagtgaaacaaatgaggatatgcgttgccagttaacagtt
tcacaaaaagctgatgtgactgagctgtgcactctcttggaagaagcagatagccagttt
gaattcacacagtttaaaactgaaatgccgaaacaaaactgtcaagataatgccgcctct
cccctgaaagttcacaaagaacttgacccagaatttctttcgggtatcaattttgatgac
agttttagttcagaggctgaaaagcacctggcagcaattgtgaagccggacaaaatgacc
tccatttcagatggtaaaacaaactgtgaaacaactgacggcacacacatttccacagga
ttgtcattgtcaagcgcagtgaaaaaagaaaattcctctcctgaagagtcgtctacctct
tcaaagcacatctccgaaggcagtagtagtgttatgtcagctgaacccaaaaatcttgac
ggagttgggcacgagctgcagaacaaaattcctctaatgcttggggtgggatttaagaca
gcaggaggaaacgttttaagagtttcgaaaaagtgtctgagcaaagctaaagctttgttt
gccggtttggaggagaatgttgtgacgagtcaaacatcaccggacaagcaaagcagcaaa
actgatactaaaagacagtttaggcgcagtgtggataatcccactaataactttctgcat
cataaagaggatcattcttcattcacagcttgtggtgatgatactgaggggcagggtcag
gcctatttttccaacacaaacaggcaggtcacatgcattcgagatggagaggctgcaaaa
agtttgataaactgcaaaagggacacagccgcgtgtcaaagtgggttccagatggccagt
ggaaaagggatttctgtttcagcaaaagctatgcaagaggccgaggcgctcttcggggac
tgtgacgcaatagacagtaacgcttgcaaacggagcatagaagccttgtctggaagtgtc
agtcatgaggaaagccttccaaaatgtgaagttcaagggatgaaagtaaactggtctaaa
gaaccactcggtgagtttgaaaatgtgaatgcaggaccagctgcgcggcaaacagaggtt
gtccagcataacgaggagacacacaatttgggttttacaaaaacaaccagaacaaatgat
gcctttttccgtggaaacccgtattcgcctgcaacggcactttcatctctctcatgcaca
tcatcaaagaatattggctcctctgccaaccatgaattgagcaatggtggtggattttgt
tcagccagtgggaacaaagcgttgatgtcagctgatgcgcttaaaaaaggggagcatctc
ttgaatgaacttcctacacctggggatgcaaacaagcaacataaaagaaaaggggatgct
ttaagaagcgtccatctctgcaatccaattcaagtttcaccacctaaaagtggtggattt
cagactgccagtggcaaaggggtggccatttcatccacagctctcaagaaagcaaagatg
ttgttgattgaatgtgatgaagttgagaatacaatctttgtaaaaccaaccctttccgaa
atgccagttcctggtccaacacccaggaatagtggatttctggcagccagtgggaagcga
gtagcattttcatctgaggtcctccagaaggccaaagctctcttcagtgacatcaggttc
aatgcagagatcccaactgttacagacacaagggacagcggcaagacacaagacgaggct
gaagttacagagaaaatacattgtggtttcacaacggcagggggagcaaaagtccacgtg
tcaaagaaaaatctgttggaagcaaaaaaccttttgacagaattcgatgacagttctatt
tcagcagaagcaatgcaagaagcggatgcttacttcaaggactgtgacattatggatgat
aacaatggcatgtcagtaaaacagaagaaaggtatagcacctggctgcggaagaggcagc
gagaagaaaaaccttttaagatgtaaagtagaccagaggttgaaaataaacatctctgaa
gagcttgcaaggggacatgctgagtttgaaaatgtgagcatggggttagttgaaaaccat
gaaagaatgctgcatcctgatgtagagattcacaaaggtgcttttaagaagacattggat
gtttccaatgcagctgctctacatggaaacccatctttgatgacaaagactcctcctccc
ctgtcgtgcacaacatcaaagaacattagttcccccaccatgaatgaattgagcaaaggg
ttcagtacagccagcgggaaaaaggtgtctgtgtctgatgacgcaatgacaaaagcaaag
tctctattgaatgaaagtgctacattcgaggactcaaacaaaccacttaaacataaagaa
agcacttttcccacacagaatggtggatttcagactgccagtggcaacggagtggctatt
tcatctgcagccctaaagaaagcaaaaactctgttcagtgagtgtgatgaagttgagaat
acaatctttgtaaaaccaacccattccaaaatgccagttcctggtccaacacccaggaat
agtggatttctggcagccagtgggaagcgagtagcattttcatctgaggccctccagaag
gccaaagctctcttcagtgacatcaggttcaatgcagagatcccagctgttacagacaca
agggacagcggcaagacacaagacgaggctgaagttacagagaaaatacattgtggtttc
acaacggcagggggagcaaaagtccacgtgtcaaagaaaaatctgttggaagcaaaaaac
cttttgacagaatttgctgaatgtcatgattcaaactcaacaatcccacatgacatctgt
aaatcagatccatcaatagtgaaaggtgtgaaaacaccttgtaatcccaccacaggcggt
gacatggacatgtttagtgccccttgggtagttgaaaatgaatctcctcaaagtcaaagt
gtacccaggtgcatttctatcgaagaccaggcccatgcagatgcatttagtgtaaaagaa
ggccaaatgaccccagcagtatcgggcaacctccatgacggcctagtgtcacgtgtgttg
gactataaaatacagcagaccagcagcagagagggatcaaaggtcaaaaggccacagatg
tcttcagttctgaacttccagtcacttaacctaagcggctgcactgaaacccagcagaag
ttgttcgcccaggaagctctggactgcaccaaggctttgttagaggacgaaggtctagct
ggccaaagtctctcaatgactttagaaaatgccagccacagatctgtagcgaaacgacaa
gggacagagaaaagattgatcgaggacccagatatggctggtcagcctcccctgaaaaga
cgattactggaagaattcgacagaactgttcatggtcccagaagttcaacactccatccg
gaaaagagttgtccaaatggtgtgatgaaagacagaaggatttttaagtacagcgtctct
ctccatccaaacatcacgaggccacacgccaatggaaaaatgtatgtggaaaccagatta
caagatacaacaccaacacaatactcaaccccagaagaaaaccgatcagcacactccggg
aagccagcgtttgttcctcctttcctcacaaatacaaagacggagagtcgcaggaacaca
atgctcaaggacaacataagaacaccttctgcttttgttcctcctttcaaaaaacaaaga
ccttttgtccgggagagctctgctaaaccacaggtggaggagaaggaggataaacaccac
catctctttgtaatgccctttaacagaaacccttatgtaccacccacacacaaaaaacaa
agcacttcagaattaactgctgataaaagcaaagaagacattgagacggtggccttggcc
cacaatacaaatgataatctgataaatagtaaaaacctgccggttggctgtggatcagag
ggctctgctgcagagacatcacatatggaggacacattgtccagaagccaagacatattt
cagaatcttcataatgtagagctggcacgagatatgcaagatatgagaatcaggaaaaag
aagcgcctgaccattcgacctttcccggggagtttgtttctcaccaaaagctcaggagcg
acaaggataccattaaaggctgcagtaaatggaaggcctcctgcaagatacacccccaaa
cagctgtacggacacggagttcaccagcatgtgtgtgagatctccagtgagacagcagaa
tcgtttcgcttccatttgaagcagttcatcaaacaggaagcttttctcgacggaggtggc
gttcagcttgctgacggaggatggctgatccccagcaaggatgggactgcagggaaagaa
gagtttcttagagcattatgtgacaccccaggtgtggatcctaaactgatcagtgaggct
tgggtatacaatcactaccgatgggttgtgtggaagcaggcgtccatggaaagatcattt
ccagaaacaatgggcggcctctgtctcaccccagagcaggttctcctgcagctgaagtac
aggtatgatgttgaggtggaccacagccgtaggccggctctgagaaagatcacggaaaag
gacgacacggcagccaaaacgctggtcctctgtgtctgcggggtcgtctccaggggtcac
tccccaaacagacagagcttcaacgacaccaagactccacaaggtgccgatgccaaggta
gaaagtccatctgcagttgtgtggctgacagacggctggtacgccattaaagcccagctg
gatgaacctctcaccgccatgcttcacaccggtcgagtggctgtcggtggcaaattgatc
atccatggtgctcagctggtgggatcacaagaagcttgcccccctctggaggcacctgaa
tctctcatgttaaagatttgcactaatagcagcagacccacacggtggaatacaaaactg
ggatttcacagggatccaaggcccttcctgctgcctgtctcctgtttgtacagcagtgga
ggaccagtaggatgcgtggacattatcgtactgagaagctaccccttacagtggatggag
aggaaaccagacgcaggcgttgtcttccgatctgttcgtgcagaagagaaggaggcgagg
cgatacaactgccacaaacaaaaagctatggagatcctattcgccaagattcaagacgca
tttgaaaaggaggacaaaggtgataacaaacctcaacgtagaaggcggacagtcagtcgt
cagggtatcgcaagtcttcaagctggagaggagctctatgaagcagtgggggacgaccca
gcttacctcgaggctcatctgagtgaacagcagttggagactctcggcacctacaggcgt
tctctgatggagaagaggcaggctgaactgcaggatcgctaccgacgagctttagaaagc
gcagaggacagcgaaggtagctgtcccaagcgagacgttacacctgtgtggagactctgt
gttgctgactccatggaccaacacggcagtgtttatcagttgaacctttggcgaccctcc
tcggatctccagtctttactgaaggaaggctgtcgatacaaagtctataatctcaccact
tcggatggaaagaaacatggaggtggcacagctgttcagctgactgggtcaaagaaaccc
agtttcaggtcctacaggctcctcaggaatggttatcaacacgttttcgaccgagggtct
ctacccgtactgtggatcttcaaaacccagaattccagtcgctgtgtggagaagttgatc
tcacaggatatgtaa
DBGET
integrated database retrieval system
