KEGG   Cyclopterus lumpus (lumpfish): 117746514
Entry
117746514         CDS       T09199                                 
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
clum  Cyclopterus lumpus (lumpfish)
Pathway
clum00562  Inositol phosphate metabolism
clum01100  Metabolic pathways
clum04012  ErbB signaling pathway
clum04068  FoxO signaling pathway
clum04070  Phosphatidylinositol signaling system
clum04081  Hormone signaling
clum04140  Autophagy - animal
clum04150  mTOR signaling pathway
clum04210  Apoptosis
clum04218  Cellular senescence
clum04370  VEGF signaling pathway
clum04510  Focal adhesion
clum04620  Toll-like receptor signaling pathway
clum04625  C-type lectin receptor signaling pathway
clum04810  Regulation of actin cytoskeleton
clum04910  Insulin signaling pathway
clum04914  Progesterone-mediated oocyte maturation
clum05100  Bacterial invasion of epithelial cells
clum05132  Salmonella infection
clum05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:clum00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    117746514
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    117746514
   04370 VEGF signaling pathway
    117746514
   04068 FoxO signaling pathway
    117746514
   04070 Phosphatidylinositol signaling system
    117746514
   04150 mTOR signaling pathway
    117746514
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    117746514
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    117746514
  09143 Cell growth and death
   04210 Apoptosis
    117746514
   04218 Cellular senescence
    117746514
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    117746514
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    117746514
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    117746514
   04625 C-type lectin receptor signaling pathway
    117746514
  09152 Endocrine system
   04910 Insulin signaling pathway
    117746514
   04914 Progesterone-mediated oocyte maturation
    117746514
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    117746514
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    117746514
   05100 Bacterial invasion of epithelial cells
    117746514
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:clum04131]
    117746514
Enzymes [BR:clum01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     117746514
Membrane trafficking [BR:clum04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    117746514
SSDB
Motif
Pfam: PI3Ka PI3_PI4_kinase PI3K_C2 PI3K_rbd PI3K_p85B DUF2321 Colicin-DNase ABC1 Retrotran_gag_4 Ribosomal_S15
Other DBs
NCBI-GeneID: 117746514
NCBI-ProteinID: XP_034411588
Ensembl: ENSCLMG00005004900
LinkDB
Position
17:complement(16580409..16591542)
AA seq 1068 aa
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGPHSKALYVYPPNVESSAELPRH
YYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPID
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKYPEMTIIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDTDNEQLRQVCNRDPL
SEITEQEKDFLWRHRQDCVNMPEILPKILLAVKWNSRDEIAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
NT seq 3207 nt   +upstreamnt  +downstreamnt
atgcctccaaggccttcctcgggagaactatgggggatgcacttgatgccccccagcatc
ctagtggactgccttctgccaaatggcatgattctcacgttggagtgtctccgggaggcc
acgctgattacagtcaagcatgagcttttcaaagaggccaggaagtaccctctttaccat
ctgctgcaggaggagagctcctacatctttgtcagtgtcacccaagaggcagagcgggag
gagttttacgatgagaccaggaggttgtgcgatcttaggctcttccaggccttcctcaaa
gtcattgagccagtaggcaacagagaagagaaaattctcaacagagagataggttttgcc
atcggaatgcctatatgtgagtttgatttggtgaaagactcagaagtgcaggacttcaga
aggaacattttaaatgtttgcaaagaggctgtggaccttagagacagtaacggaccccac
agcaaagctttgtacgtgtatcctcccaatgtagaatcttctgcagaacttcccaggcac
tactataacaagctagataaagggcaaatcattgtggtaatatgggtcattgtgtcaccc
agcaatgataagcagaagtatacccttaagatcaaccatgactatgtgccagagcaggtg
attgctgaagccatccgtaagaagacacgtagcatgctgctctcccaagagcagttaaag
atgtgtgtgcaggagtatcagggaaagtacatcctcaaagtctgtggctgtgacgagtac
ttactggagaaataccctctgagtcagtacaagtatgtgcgcagctgtatcatgttggga
cggatgcccaacttgatgctaatggcaaaagacagcctgtattcccagctgcccatcgac
aacttcaccatgccgtcatatgcaaggcgaatatccacagcaacgccctacatgaatggg
gaaacagccaccaagtctctctggactatcaacggaacgctgaggatcaggatactgtgc
gccacttacgtcaatgtcaacatcagagacattgacaagatctacgtcaggactgggata
taccacggtggagagcagttgtgtgacaatgtcaacacccagcgcgtgccctgctccaac
cccaggtggaacgagtggctgaactacgacatgtacattccagacatcccccgtgctgcc
cgactctgcctctctatctgctctgtgaaaggaaggaagggagctaaagaggagcactgt
cctctcgcctggggaaacattaacctgtttgactacacccacacattagtagcagggaag
atggcactcaacctctggcctgtcccacacggcctagaagacctgctcaaccctattggt
gtaaccggctccaacccaaacaaggaaaccccttgtctggagctggagtttgaccatttc
agttgccctgtcaagtaccctgaaatgaccatcattgaggaccatgcaaactggaatatc
tccagagagcttggctttaattactgccacaccggtttgagtaacagactggcgcgtgac
aaccccctgaccgacactgacaatgagcagctacgacaggtgtgtaacagagatccgctg
tctgaaatcactgagcaggaaaaagactttctatggagacacagacaagactgcgtcaac
atgccagagatccttcccaagatcctcttggctgtgaaatggaactcaagagatgagatc
gctcagatgtattgcctcctgaaggactggcctgctatcaagccagagcaagccatggag
ttgcttgattgcaacttccctgatcctatgatcagagagtttgctgtaaagtgccttgag
aaatacttaactgatgacaaactctcacagtacctcattcaactggttcaggttctaaag
tatgagcagtaccttgataacccactggcacgcttcttgctgaaaaaggcattaaccaat
cagaggataggacatttcttcttttggcatttaaagtcagagatgcacaacaagacagtg
agccagcggtttgggctactgttggagtcctactgccgggcgtgtggcatgtatctgaag
cacctgagcagacaggtggaggccatggagaaactcatcaatctcactgacctcctcaaa
caggagaaaaaagatgaggcacagaaggtgcaaatgaagtttttggtggagcagatgaga
aggcctgactacatggacgccctgcagaacttcacctccccactgaatccagcacatcag
ctgggaaacctccgcctagaggaatgcaggatgatgtcatcagccaagcgaccgctatgg
cttaactgggaaaacccagatatgatgtcagagctgctctttcagaacaacgaaatcatc
ttcaaaaatggagatgatctgaggcaggacatgctgacgctgcagatcattaggataatg
gagaacatctggcagaaccaaggccttgatctcaggatgctgccgtatggttgtctgtca
atcggtgactgcgtgggtttgatcgaggtggtgaggaactctcacaccatcatgcagatc
cagtgtaaaggaggcctaaagggggcactgcagttcaacagccacacactgcatcagtgg
ctgaaggataagaacaagggagaaatgtatgaccaggccatagatctgttcacgcggtcg
tgtgcaggctactgtgtagccacgtttatcctgggcatcggggacagacacaatagcaac
atcatggtcaaagatgacggacagctgttccacatagactttggccatttcctggaccac
aaaaagaagaagtttgggtataagagagaacgcgtgccctttgtgctcacacaggacttc
ttgattgttattagcaaaggaactcaagagtgcactaaaacaagggagtttgaaaggttc
caggagatgtgttacaaggcgtacctggcaatccggcagcacgccaacctcttcatcaac
cttttctccatgatgctgggctcagggatgcccgagctgcagtcgtttgacgacatcgct
tacatcagaaagaccctggcgttggacaagacggagcaggaggccctggactacttcatg
aagcagatgaacgacgctcaccatggcggctggactaccaagatggactggatcttccac
acaatccgccagcatgccatgaactga

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