Cyclopterus lumpus (lumpfish): 117746531 Help Entry 117746531         CDS       T09199                                  Symbol obscnb Name (RefSeq) obscurin   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism clum  Cyclopterus lumpus (lumpfish) Pathway clum04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:clum00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     117746531 (obscnb)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:clum01001]     117746531 (obscnb)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:clum04131]     117746531 (obscnb) Enzymes [BR:clum01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      117746531 (obscnb) Protein kinases [BR:clum01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    117746531 (obscnb) Membrane trafficking [BR:clum04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     117746531 (obscnb) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Ig_5 Ig_4 Ig_6 Izumo-Ig V-set_CD47 SOS1_NGEF_PH fn3 C1-set RhoGEF Ig_DSCAM-DSCAML_C PH Receptor_2B4 Pur_ac_phosph_N IQ IQ_SEC7_PH DUF1722 RHG20_PH Motif Other DBs NCBI-GeneID:  117746531 NCBI-ProteinID:  XP_034411609 LinkDB All DBs Position 17:20151902..20199208 Genome browser AA seq 6564 aa AA seqDB search MDKNLFGGVPRFLTRPKAFAVCAGKDATLSCTIVGSPTPLITWEKDKLKLTSGGRFKTVE DGDAYRLTIYDLTLEDSGQFMCRAKNSVGEAYAAVTLKVALPTEMAHRAPGFMVKPASAR VGLGDDVVFHCRVVAYPDANFDWEKDGRYLGETNRIKVVSDGDSSILKIQSARHLDSGTY TCRAQNAVGRSHAAAALVVDAQDSRHLAADKNTSLLSHLQKRKEEMNKDISIYRTEESRS SVSSSTSPSSKANVADGLSSLRLPKGVFTRTCTVTEGKHAKLSCFVTGHPKPHIIWRKDG SNINEGRRQVIYEDQAENFILKILYCKQSDNGLYTCNATNMAGQTYSAVLVTVKEPKVPF RRKLQDVEVQEKTSATLMCEVPVSATQASWFMEETRLQQSNKYYIEQEGNLRRLIIHNVT TNDDGVYICEMKEGSRTVAELTVLGNITKKLPRRTVVPVSDTVIFCVELEHPFPDAYWTR NGEKLKKDSRISIACTLRQYTLTIRDCQADDSGEVAFVAGDCKTSTRFSVTAARKHPPDP PVDAVVQNKTDSSVTIRWSPPDSDRPVPIKGYIVEKKKIGTQTWQRCNAGETVVSTEITV CSFTEEATYQFRISAMNDFGQSPHLEVPGSFFLEPSADIKKGLANSVATSGEEFSISVEL SAVCSGFWSLGGRLLRSGADYLITRSKNTHTLLIRVVTAEMNGAEVKFVGGGSQSGCILS VTAPSFKFTNKSDVLEVVSCSAQATAQLTAEVSDYDAQVVWMRNGREVKTGKKYEYMNVD RKRTLTVHNVTEEDVGTYECVLADDRMPLQLSLKDEPAKFLNKARGTVGMTSSLKGDLEL SCEVSPASAAVVWRKDQAQMAEDQRTAFVSKGTQRKLVIKNAKKRDEGHYSCETAADKVT FQVKIKETQAASAFSNKESVQKQVKATLSQKATLSCSVSDGKTEVKWYKDGKLLISSRTI YTEAKGDARQLVIEKVEKSDAGEYTCEAGEDKLVFKIFVSETQSAFSNKESVQKEVKATS SQKATLSCELADTKTEVKWYKDGKLLTSSKTIHTESKGKSRQLVIDSVEKKDAGEYVCEA GAEKLVFKIQVAEAQSAFSNKESVQKEVKATSSQKATLSCELADTKTEVKWYKDGKLLTS SKTIHTESKGKSRQLVIDSVEKKDAGEYVCEAGAEKLAFKIQVADTQVQSASSHKESVQK DVKATLSQKATLSWEVSDSKTEVKWYKDGKLLATSKAIHADLKGKSRQLVIDSVEKKDAG EYVCEAGAEKLVFKLQVEGVSPEAKSPFINKESVQKEVNAALSQKATLSCEVVDNKTQVK WYKDGKPLSTSRAVHTESTGQIRQLVIDSVEKRDEGEYVCEVGTHKVVFKVQATEIKSAF SNKESVQKEVKATSSQKTTLSCDVSDTKTEVKWYKDGKLLTSSKTIHTESKGKSRQLVID SVEKKDAGEYVCEAGAEKLVFKIQVAEAQSAFSNKESVQKEVKATSSQKATLSCELADTK TEVKWYKDGKLLTSSKTIHTESKGKSRQLVIDSVEKKDAGEYVCEAGAEKLAFKIQVAEA PAGFSNKESVQKEVKATSSQKATLSCDVSDTKTEVKWYKDGKLLTSSKAVHTESKGKSRE LVIEKMDKKDVGEYACESGAEKLVFKLQMTDAAVKFQRTLVKDTCVVEVSEKVVLSTELT KEGGSVTWFREGVELKEGSKYEMKKEGLSRTLIVKSSESKDSGTYSCQTADDKLEFKVQV KDPALKFVVPLKAATVELGGTLTLTCELNRASGDVVWRHDGREIKPGGRHCVRADGAKRV LAVTGATKEDEGDYDCECRNDKTSARVSSKAPRLVRLTAKLNNVAATEGKDAVFKCAVSP ADADVKWFHNNVPVTAGPRYRIERGGGSHSLTIASVAQKDAGEISVDAEGKSCKASLQVQ HEPVTFKKKLENLTAEEQSEVKLEVELSKPSEEVRWMKNSVVLQPAGNMEIRVDGAKQTL VFKSVTCADRGVYSCETLDDKTQTKLNVEMKKIQVTKGLTETQVHETETVTFEVELSQAD VEGSWTRDGAKLKSGANCRITALGKKQALTLSNLKREDAGTISFQAEGVHSSGKLIITEP PAMISKPLVDIAAPEKEKVTFECELSRTNADVKWFKDDAELKVGKTFGIHSSGRKRSLVI NKCTNGDAGTYICRTADDNTAATLTVHARDIKIVKKLEDVEVMEKESAAFVCEISHDEVE CQWHKGSIKLKAGDNIKMRQEGRTHVLLFKTVAPEDTGEIKFTADKASSAARLKVKELPV KFVKRLRDKIAMYKHRGHLECQVSRASAKVKWYKNKTELKHGKKYEIRSEDVYRKLLIND VDSGDEDTYTCDGTDDRTSCKLLVEEQAISIVRELSSVEVTEPFAAVFEVEISMELVKPP TWTLNGVAVQESADVEMEKEGAMHRLTFKKTKASMTGPVQFTAGKSKSLAQLAVKERPLE VAEPMKDVKAKEKSSAILTCKFSASPKEVKWFKGQGPLAASDKYNIKQDATRAQLTIQRL TEEDSGEYRCRSGPAETKGTLTVEARDIKITKHLADTEVDEDSDAAFTCEINYADEEVQW LLSDKVLFTNEVNAITHDGKAHKLTLKNLAPQDGGTITFKVRKVKESVTLKVKEKRAVFL KSLDDVIGEEKGMITLACEASKPRVSPTWRKESQVLKAGSKYELLHTGKSLGLIIKDVTN EDAGEYSCDLGTEVSKAKVTVREIGIGITKWLKSAEVNEGETCSFECILSRESTDECSWT LNGHAVANGGRFKVTSKGRKYMLTVKDVVPADAGEVVLNIKDLSSKTTLTVEAAASSVSQ GLQSVSAVRGEDAVFTCEVTQCSSTVKWAKESKTIKKSQKYDISQEDKVMKLIVLNVAAQ DSGEYSCEVVGGATTRATLDVREPTHVFTKALMDSRAEEGSAVVLQCEIAQCPSTVIWLK GPAELKAGGRYEMSQKDGILTLTIKHLEEKDTDIYTCDVGTAKSVAKVTVNALPPTYIEK LQSQEAEEGASVTLCCELSKPGVPVEWKKGTQILKSGQKYQMKQKASVNQLLIDQVEPED SGDYSCVCGDQKTSASLKIKARPVTFKQKLEGQEAEEGASVTLCCELSKPGVPVEWKKGT QILKSGQKYQMKQKASVNQLLIDQVEPEDSGDYSCVCGDQKTSASLKIKARPVTFKQKLE GQEAEEGASVTLCCELSKHGVPVEWKKGTQILKSGQKYQMKQKASVNQLLIDQVEPEDSG DYSCVCGDQKTSASLKIKARPVTFKQKLEGQEAEEGASVTLCCELSKPGVPVEWKKGTQI LKSGQKYQMKQKASVNQLLIDQVEPEDSGDYSCVCGDQKTSASLKIKARPVTFKQKLEGQ EAEEGASVTLCCELSKPGVPVEWKKGTQILKSGQKYQMKQKASMNQLLIDQLEPEDSGDY SCVCGDQKTSASLKIKAVTLPTTGQTPKEQLLKQEIQRDSRELKVGGEVLPVVVVRDLES REAEEGHAVTLRCELSKPGLPVEWRRGTRVLSRGEKYQMKQIGSSYELQISDLTPGDTGS YTCRSEDALCSASLVVNAAPVIFTKELESQTADEGDSVTLHCELSKAGVPLEWRKGELGL CPCAKYDIRQAGHLASLVIHDVDPEDAGSYTCDAAVHRSAAQLDVKARPVLFKTQLQNLE RREGESASLRCETTTPGAGVVWRLGDRPLASSGKYHLKQEGTVVELAIYKLQGADSGEYS CDTGDQRTSAVLTVQEVEVNILNFLESCVVYEGEDVHFECRVSRGDAPQAQWKLQDVPLQ DNEMNLILREGPVHGLTLRGVTPADSGTVTFTVGNHTSTASLTVRAAPVLFKKELESQEA REGDAATLSCETSSPDCQVIWLKGSTVLTHGEKYNTEQRASTHILVVHKLNVQDGGEYTC DTGGRKSTATLTVKEHVRLVRELCDLTVATGQDAVFEVELSHSGVTHGEWWLADNLLQNN DLNQMSVRGAVHRLVLKMVTTDESGDVAFVVGEEKTVACLLVEEKPKVLILERPHDTVAV EGETATLACTVSDAKAAVSWIRNNVAVQAGLKYEPRSNGAFRQLCIHNLVPEDSGTYTCD TGDAQCGVTLTVEGAPVFFRKELKNLDALEGEEVTLRCEPSKPGVRVEWRKGGMVLQPGK KCEMRQEGCVQELVLRNLEPEDSGYYTCDAGDQLTTASLAVQVKEVFVVCGLKTIDVFVG EWATFSCQLSGRAPVQVQWWLDGTLLENSPFSEIELSPGHIHTLTLKNLATDDSGTVAFK AGSLTATAKLLVKDPTVEVVSEMEDLRVLKNQPAEFICQYSRPVTAQWKKDGRPLQPDGR RVLVEQDWNVARLYISHASAEDAGAYACEAEGTRVVASLYVEGKPIDLVQGLENVETFDG GEALFECALSRPESKDCRWLLDGKPVKESPNAEIVTFESGRRHLLLLKELRVSDSCTVTF KAGAASTSAQLSVKGWQLDVVKPLEDKVAAVGEKVEFCVELNERVPVAEVAWYANGVEIK SSDLWAMRADGCSYRLVLRQAPLLPQQEITFAARDALSLAKLTIITVSDPPEDPEVLGKT EKSVTLSWFTPLHDGGSPILGYRVEMRLTDSALWLPSHSEPVCNTEFVVENLTPGSGYRF RVAAINRAGIGEPVELPQTVQLGVEAKQGEPETMGQPSLPPEAAEEGDVHELWEETAKKR RMSREPTLDSITEQPEEVVGGQNKSAQKDSKSSEKVEVKSVERAQATASKKQTASKLLTG SEDESVPGGSTLVSYLKKSSKSTVTATNEAEAEAISTERFFEHFQMAEKRTVETTAIQQT DAKPAPAEETDVMEISKEDEPELRDAAIKIQAAFKGYKARKVMRPVFKDAFKDQTKEPNG TIHLECVAEGKPDKMRWLKDGEPLQDGKHHHIDIYNDGTCSLVITAIDTKDTGVYTCEVT NKYGVTSHSGKVTVGTARESSGRRPLTVGYSADSEPESSSGSEMDESLRQASRRLRRLLR TRLPPAVEEEPFVSADEGDLSHPDPHSYREDDSYIYIRFDSRAEADVASKRFQQMFTIHG VPVETTILEAGFLKVELRIKKMGYTQDGTQTPTPDRQPPAFMAGAAAAPVFLTELHSQDV PDGYPVSFDCVVIGKPTPAVHWYKDGKLLEENDHYMINEDQEGCHQLIITTVLPTDMGAY RCTAENGSGIAATKAELRVDMSCSSDYDTAADATETSSYVSAKGYMSRETETFESVAEDD QLPQVVDELHDVHVSPGSPVAKMQLKLKGFPKPRVYWFKDSHPLRPSERILLLAERDVHA VEILQVKKEDMGEYSAYISNAAGSAYSSGRLVVLNPGEMMPQVKRDPKVPLVPPRFLERF SNRKVKQGASITLSVKVEGSPTPMVSWLKEESMEDVLWIKPDTKGYKIASSGRQHSLILM DVGTEYTGAYTCIATNRAGQSICTAHLEVDDVPQPKKTSEVLGITVSAPEEEAGRAKEIK IPYLGEVGTEEFLMKLTSQITEMVSAKMTQDSLQNLEVLQWMKSWPKTTTSLRVPGDSDD ETKTPSPSPHHGRSRPPSLIADSSSESDEGDARGEMFDIYVATADYNPTLASTEAIALKV GQYVEVLDSAHPLKWLVRTKPTKTTPSRHGWVSPAYLDKKLKLSADTSDLPETNVEEVSE GEYKRKLFRLIQDLMKGEAEFVKEMDFFTSHHLKHADGPDAPPDVSSQKEAIFRNLDDIK SFHSKAFLPKLNDCDTDDDVAMCFLKNKEGFEKYLHYLVGQSLAECAVSDTAVHRFFKEY TEKVQASADPADPPVRSINASLQQPLERIQKYKAALKELIRNKAKNGQNCCLLEEAYAMV SALPQRSENTHHVTMIENYPATLEVLGEPMRQGPFQVWEGAPGIRTSSRGHNRHVFLFKN YCVICKAKRDSNTDTQAYVFKNMMKLNNIDVNETVEGDDRAFEIWHEREDSVRKYTLQAR TVTIKNSWLRDFRELQQRYSTPAWSPPDFDEILANCTAELRQTVKLACKVTGVPKPAVTW YKDGRPVEADPHHIIIEDPDGSCTLILDNMTADDSGQYMCFATSSAGNASTLGKVTVQVP PRFVNKMRNAIFVAGEDTQFTCVIQSAPNPKIRWFKDCRLLTDQDKYQTYSELRSGVLVL VIKNLNERDLGRYECELCNRLGSAKCAADLVPPSAVARTGEQAITIEVTEQETRIPKKTI IIEETITTVVKNQRMRRHKSPGFAVAGAHRSETSTPEAPAARPRRMPTARKSAIPTLCVT EPGGAEARAAESKPRWIEVEEVIEYKVNKSPRLSRRRGVSPAGSDRATAPSRSKRSPPEN PNANNSNNNLVGQAQAQAQLQAQAQLQGDSQPLPWEEEEEEEEGGVASDSGEPREISSAL TPACEDGEDPDDDQTVIFEPDDEDEDRVSPGEREPEFLTQGGRVLTLEDLEDYVPEEGES YGSSGAHKPAKEKPCEISVLQREIGGSTVGQPVLLNVGRPVAAPRQRSGGFFSRFREHLS SGGVFSPAASSPQASGGQSRTERRVPIQVSHAKIEVKPSYRSEVQRVEGGRRSFRTKVST QTFGYTSVGNPVTLQISDDLRPDQ NT seq 19695 nt NT seq  +upstreamnt  +downstreamnt atggataaaaacctgtttggcggagtgccgcggtttctcacccgcccgaaggcgttcgcg gtgtgcgcgggcaaggacgccacgctgagctgcaccatcgtgggcagcccgaccccgctg atcacctgggagaaggacaagctgaagctgacgtccggcggccgcttcaaaaccgtggag gacggagacgcgtaccgcctcaccatctacgacttgacgctggaggacagcggccaattc atgtgccgggccaaaaacagcgtcggggaagcgtacgccgccgtgaccctcaaagtggcg ctgccgaccgagatggctcacagggcccccgggttcatggtcaagcccgcctccgctcgc gtgggtttgggagacgacgtcgtcttccactgccgggtcgtcgcctaccccgacgccaac ttcgactgggagaaagacggccgctacttgggggagaccaaccgcatcaaggtcgtttcc gacggcgacagcagcatcttgaagatccagagcgcgcgtcacctggacagcggcacctac acctgcagggcgcagaacgccgtcgggcgctcgcacgccgcggccgctctcgtcgtggac gcccaggattcacgccacctggccgcggacaaaaacacctccctcctttctcacctgcaa aagcgcaaggaggagatgaacaaggacatctccatctaccgcaccgaggaaagcagatcc tccgtttcctcgtcgacgtccccctcctccaaggccaacgtcgccgacggcttgagttct ctgaggctgcccaaaggtgtgttcacccgcacctgcacggtgaccgagggcaagcacgcc aagctcagctgcttcgtgacgggtcaccctaaaccccacatcatctggaggaaggacgga agcaacatcaacgagggccgcaggcaagtcatctacgaggaccaagccgagaacttcatc ctcaagatcctgtactgcaagcagagcgacaacggcctctacacctgcaacgccaccaac atggcgggccagacctacagcgccgtgttggtcacggtcaaagagccgaaggtgccgttc aggaggaagctccaggatgtggaggttcaagagaaaacctcggccactctgatgtgcgag gtgcccgtcagcgccacccaggccagctggttcatggaggagacgcggctgcagcagagc aacaagtattacatcgagcaggaaggcaaccttcgacgtctcatcatccacaacgtcacc accaacgacgacggcgtttacatctgcgagatgaaggagggcagtcgcactgtggcggag ctcaccgtcctgggcaacataacgaagaaacttccccggaggacagtggtccccgtcagt gacaccgtcatcttctgtgtggagctggagcatcccttcccggatgcttactggacccgc aatggagagaaactcaagaaagattcccgtatttccattgcgtgcacgctcagacaatac acgctcaccattagagactgccaggcggacgactccggagaggtggcctttgtggctgga gactgcaagacctccactcggttctccgtcaccgctgcaaggaagcatcctcccgacccc cccgtcgacgccgtggtgcagaacaagaccgactcatccgtcaccatccggtggtctcct ccagacagcgaccgccctgtgcccatcaagggctacattgtggagaagaagaagattggc actcagacatggcagaggtgcaacgccggggaaaccgtcgtttcgacggagatcaccgtc tgcagcttcacggaagaggccacctaccagttccgtatctccgctatgaacgactttggc caaagtccccacctggaggtgcctgggagcttcttcctggaacccagtgctgacatcaag aaaggcctggcgaacagcgtcgcgacctccggcgaggagttctccatctccgtggagctg tccgccgtttgctccggcttctggtctctgggcggccgcctcctgcgcagcggagcggac tacctcatcaccaggtccaagaacacgcacactctgctcatccgggtcgtgaccgcggaa atgaacggagccgaggtcaagtttgtgggcggaggctcgcagagcggttgcatcctatct gtgacggctccttcttttaagttcaccaacaagtcagatgtgctggaggtggtgagctgc agtgcccaagccaccgctcagctgactgctgaggtgtcggattacgatgcacaggtggtt tggatgaggaacgggcgggaggtgaaaacgggaaaaaagtacgaatacatgaacgtcgac cgcaagaggacccttacggtccacaacgtcacggaggaagatgtcggcacctacgagtgc gttttagccgacgacagaatgcccctgcaactctctctcaaagatgaacccgccaaattt ctgaacaaagccagaggcaccgtggggatgacgtcgtccctcaaaggagatctggagctg agctgcgaggtttctcccgccagcgcggccgtcgtgtggagaaaggatcaagcgcagatg gccgaggaccaaaggaccgccttcgtctccaaaggcactcaaaggaaactcgtcatcaag aacgccaagaaacgcgacgaaggacattactcctgcgagacggcggcggacaaagtcaca ttccaggtcaagataaaagaaactcaagccgcatcggcattctccaacaaggagtcggtc cagaagcaggtgaaagccacgctctcccagaaggcgaccctcagttgcagtgtttcagat ggcaaaacggaggtgaagtggtacaaagacggcaagttgttgatatccagtaggacgata tacaccgaggcgaaaggcgacgctcgtcagctggtgattgaaaaggtcgagaagagcgac gccggagagtacacatgcgaagccggagaggacaagctggtcttcaagatatttgtgtcc gagactcaatcggccttctccaacaaggagtcggtccagaaggaggtgaaagccacttcc tcccagaaggccactctgagctgtgagctagctgacaccaagacggaggtgaagtggtac aaggacggcaagctgctgacttccagtaagaccatccacaccgagtcgaagggcaagagt cgccagctggtgatcgatagcgtggagaagaaggatgccggagagtacgtctgtgaggcc ggagccgagaagctggtcttcaagatacaggtggcagaggcccagtcagccttctccaac aaggagtcggtccagaaggaggtgaaagccacttcctcccagaaggccactctgagctgt gagctagctgacaccaagacggaggtgaagtggtacaaggacggcaagctgctgacttcc agcaagaccatccacaccgagtcgaagggcaagagtcgccagctggtgatcgatagcgtg gagaagaaggatgccggagagtacgtctgtgaggccggagccgagaagctggcgttcaag atacaggtggcagacacacaggtccagtctgcatcctctcacaaggagtcggtccagaag gacgtgaaagccacgctctcccagaaggccactctgagctgggaggtttctgactccaag acggaggtgaagtggtacaaggacggcaagctgctggccaccagtaaggccatccacgcc gatttgaagggcaagagtcgccagctggtgatcgacagcgtggagaagaaggacgccgga gagtacgtctgcgaggccggggccgagaagctggtcttcaaattacaagtggaaggtgtt tctcctgaggctaaatcccctttcatcaacaaagagtccgtgcaaaaggaagtgaacgcc gctctctcccagaaggccactctgagctgcgaggtagtcgataacaagacgcaggtgaag tggtacaaggacggcaaaccgctgagcaccagcagagcagttcacacggagtcaacgggt cagatccgtcagctggtgatcgacagcgtggagaagagagatgaaggagaatacgtctgt gaagtgggaacacacaaagtggtgtttaaagtacaggcgacagagatcaaatcggctttc tccaacaaggagtcggtccagaaggaggtgaaagccacttcctcccagaagaccactctg agctgtgacgtctctgacaccaagacggaggtgaagtggtacaaggacggcaagctgctg acttccagtaagaccatccacaccgagtcgaagggcaagagtcgccagctggtgatcgat agcgtggagaagaaggacgccggagagtacgtctgtgaggccggagccgagaagctggtc ttcaagatacaggtggcagaggcccagtcagccttctccaacaaggagtcggtccagaag gaggtgaaagccacttcctcccagaaggccactctgagctgtgagctagctgacaccaag acggaggtgaagtggtacaaggacggcaagctgctgacttccagtaagaccatccacacc gagtcgaagggcaagagtcgccagctggtgatcgatagcgtggagaagaaggatgccgga gagtacgtctgtgaggccggagccgagaagctggcgttcaagatacaggtggcagaagcc ccagctggattctccaacaaggagtcggtccagaaggaggtgaaagccacttcctcccag aaggccactctgagctgtgacgtctctgacaccaagacggaggtgaagtggtacaaggac ggcaagctgctgacttccagcaaagcggtgcacacggagtcaaagggcaagagtcgtgag ctggtgatagagaaaatggataaaaaagacgtcggagaatacgcatgtgagtccggagcg gaaaagctggtatttaagctgcagatgacagacgcagccgtcaagttccagaggacgctt gtcaaagacacgtgtgtcgtggaagttagtgaaaaagtcgttttgagcactgagctgacc aaagagggcggtagtgtgacgtggttcagagaaggtgtggagctcaaggagggcagcaag tatgaaatgaaaaaagagggcctgtctcgtaccctgatagtaaaatcctcagaatccaaa gacagcgggacgtactcctgtcaaacggctgatgacaaactagagttcaaagttcaagtt aaagatccagctctgaagtttgtcgtccctctgaaagctgctacggtggagctgggaggt acgctcaccctgacgtgtgaactgaaccgagcctcgggggacgtcgtctggcgccacgat ggtcgcgaaatcaaacccggaggccgccactgcgtcagggcagacggcgctaagcgggtt ctcgctgtgaccggcgcgactaaagaagacgaaggggactacgactgcgagtgtcgaaac gacaagacctccgccagagtctcttcgaaagcacccagactggtgaggctgaccgccaag ctgaacaacgtggccgcgacggagggtaaagacgccgttttcaagtgcgccgtcagcccg gcggacgccgacgtgaaatggttccacaacaacgtgcccgtcaccgcggggcccaggtac aggatcgagcgtggcggcggcagtcactcgctcaccatcgcctccgtcgcccaaaaggac gccggggagattagcgtcgacgcggaaggcaaaagctgcaaagcttccctacaagtgcag catgagcctgtgacatttaagaaaaagctagaaaacctgacagcggaggagcagagtgaa gtgaagctggaggtggagctcagcaagccgtcggaggaagtgaggtggatgaagaacagc gtcgtgctgcagcccgcagggaacatggagattcgggtcgacggcgcgaagcagacgctg gtcttcaagagtgtgacttgtgctgaccggggcgtctactcctgtgaaactctggacgac aaaacccagaccaagctcaatgtggagatgaagaagatccaggtcacgaaggggctaaca gaaacccaggtgcatgagacggagacggtaacatttgaggtggaactcagccaggcggat gtcgaaggctcctggaccagggacggggccaagttaaagtcgggggccaactgccgcatc acagctctgggaaagaagcaggccttaacgttgtccaatctcaagagggaagacgcggga actatttccttccaagcagaaggagtgcacagttcgggcaaactgattatcacagagcct cctgctatgatctccaagcccctcgtggatatcgccgctcccgagaaggagaaggttact ttcgaatgcgagttgtccagaacgaatgcagatgttaaatggttcaaggatgatgcagaa ctgaaagtgggtaagacctttggcatccactcctcgggccgaaagcgttctttggtcatc aacaaatgcaccaatggagatgcaggaacttacatctgtcgcaccgccgatgacaacacc gccgccacgctcaccgtgcacgccagagatattaagattgttaagaagctggaggatgtg gaagtgatggagaaggagagcgctgcgttcgtctgtgaaatctcacacgatgaagtggag tgccagtggcacaaaggaagcatcaaactcaaagccggggacaacatcaagatgagacag gagggcagaacccatgtgctcctgtttaagaccgtcgccccagaagatacgggtgagatc aagttcacggctgacaaagcctcttcagctgcacgacttaaagtgaaagagctgcccgtg aagtttgtgaagagactcagggataagatagcgatgtataagcatcgcggtcacctcgaa tgccaagtgtcacgcgccagcgcaaaggtgaagtggtacaagaacaagacggagctcaaa cacggcaagaagtacgagatcagaagcgaagacgtgtaccgaaaactcctcatcaacgac gtggactccggagacgaagacacctacacctgtgacggcaccgatgacaggacgtcctgt aaactcctcgtagaagagcaggcaatcagcattgtgcgggagcttagctcagtggaagtg accgagcccttcgcagctgtctttgaagttgagatcagcatggagctggtgaaacctccc acatggaccctgaatggagtcgccgtgcaggagagcgccgatgtcgaaatggagaaagag ggcgctatgcaccgtctcacgttcaaaaagaccaaagcatcaatgacgggacccgtgcag tttacagctgggaagagcaaatctttagctcagctcgcagtgaaagagcgcccacttgag gtcgcagagcccatgaaagacgtgaaggcgaaggagaaaagctcggcgatactcacctgc aaattctctgcctcacccaaagaggtcaagtggttcaagggtcaggggcctctggcagcg tcggacaagtataacataaagcaggacgctacgagggctcagctcaccattcaaaggttg actgaggaagacagtggagagtaccgctgtcggtctggacccgctgagaccaaagggact cttactgttgaagcgcgcgacatcaagatcaccaagcacctggctgacacggaggtcgac gaagacagcgacgcggcgttcacgtgtgagatcaactacgccgacgaagaggtgcagtgg cttctgagcgacaaggtgctcttcaccaatgaagtcaacgccatcacgcacgacgggaag gctcacaagctcacgctgaagaacctggcccctcaggatggggggactatcacctttaag gtccgcaaagtgaaggagtccgtgacacttaaggtcaaagagaagcgcgcggtgttcctc aagtctctcgatgacgtcatcggagaggagaaaggcatgataacgctagcgtgcgaggcg tccaagcccagggtttctccgacgtggagaaaagaaagccaagtcttgaaggccggctcg aagtacgagctgcttcacaccggcaagtcgttgggactgatcatcaaggacgtcaccaat gaagacgccggagagtacagttgtgatcttggaaccgaggtttctaaagccaaggtcact gtgagagagattggcattggaattaccaaatggctgaagtcagccgaggtgaatgaggga gagacgtgcagctttgagtgcatcttatctcgggagagcacggatgagtgttcctggact ctcaatggccacgctgtcgccaatggaggccgcttcaaggtcaccagtaaaggacgcaag tacatgctgaccgtgaaggacgtcgttcctgccgatgctggagaggtggtcttaaacatt aaagacctgagctccaaaacaacattaacggtcgaagccgcagcttcgtccgtgtctcaa ggactgcagagtgttagtgctgttcgaggggaagatgctgtgtttacctgcgaggtcacg cagtgtagttccactgtaaagtgggccaaggaaagcaaaaccatcaaaaagagccagaag tatgacattagccaagaggataaggtcatgaagctgatcgtccttaatgtcgctgctcaa gactctggagagtacagttgtgaagttgttggaggtgcgaccactagagccacgctggac gtcagggagccaacccatgtattcactaaagcgcttatggacagccgagctgaggagggg agcgctgtggtgttgcagtgtgagattgcacaatgcccgtccactgtgatatggcttaaa ggccccgcagagctcaaggctggaggtcgatatgagatgtcccagaaggacgggatccta actctcaccatcaaacacctggaggagaaagacactgatatctacacctgtgacgtgggc actgccaagagcgtggcaaaggtgacggtcaacgcattgccgccaacctacatagagaaa ctgcagagccaggaggccgaggagggagcgagtgtcactctctgttgtgagctctctaaa cctggagtccctgtggagtggaagaagggaactcagatcctgaagtctggacaaaagtac cagatgaagcagaaggcctctgtgaaccaactcctgatagaccaggtggagccagaagac agtggagactacagctgtgtgtgtggagaccagaagacctcagccagcctgaagatcaag gcccgaccagtgaccttcaaacagaagctggagggccaggaggccgaggagggagcgagt gtcactctctgttgtgagctctctaaacctggagtccctgtggagtggaagaagggaact cagatcctgaagtctggacaaaagtaccagatgaagcagaaggcctctgtgaaccaactc ctgatagaccaggtggagccagaagacagtggagactacagttgtgtgtgtggagaccag aagacctcagccagcctgaagatcaaggcccgaccagtgaccttcaaacagaagctggag ggccaggaggccgaggagggagcgagtgtcactctctgttgtgagctctctaaacatgga gtccctgtggagtggaagaagggaactcagatcctgaagtctggacaaaagtaccagatg aagcagaaggcctctgtgaaccaactcctgatagaccaggtggagccagaagacagtgga gactacagctgtgtgtgtggagaccagaagacctcagccagcctgaagatcaaggcccga ccagtgaccttcaaacagaagctggagggccaggaggccgaggagggagcgagtgtcact ctctgttgtgagctctctaaacctggagtccctgtggagtggaagaagggaactcagatc ctgaagtctggacaaaagtaccagatgaagcagaaggcctctgtgaaccaactcctgata gaccaggtggagccagaagacagtggagactacagttgtgtgtgtggagaccagaagacc tcagccagcctgaagatcaaggcccgaccagtgaccttcaaacagaagctggagggccag gaggccgaggagggagcgagtgtcactctctgttgtgagctctctaaacctggagtccct gtggagtggaagaagggaactcagatcctgaagtctggacaaaagtaccagatgaagcag aaggcctctatgaaccaactcctgatagaccagctggagccagaagacagtggagactac agctgtgtgtgtggagaccagaagacctcagccagcctgaagatcaaggcggtgactctg ccaactaccggacagactcctaaagagcagctcctcaaacaggagatccagagagattca cgagagctcaaagtgggaggtgaagttcttcccgtcgtcgtcgttcgagacctggagagc cgagaggccgaggagggccacgccgtcactctgcgctgcgagctttctaaacccggactc cccgtcgagtggaggaggggaactcgagtgctgagtcgcggagaaaagtaccaaatgaaa caaatcggatcgagctacgagctacagatctcggatctgacacccggagacacgggaagc tacacgtgccgttcggaggacgcgctgtgctcggcctctctggtcgtaaacgctgccccg gttattttcacaaaagagctcgagagccaaacggctgacgagggggacagcgtcaccctc cactgtgagctttctaaagccggtgttcctttggagtggaggaaaggggagctcggcctt tgtccttgtgccaagtatgacattagacaagcgggacacctggcgtcactagtcatccac gacgtggaccccgaggacgccgggagttacacatgtgacgccgcggtccatcgaagcgct gcacaactagacgtgaaggcccggcctgtccttttcaaaacgcagctgcaaaacctcgaa agacgggaaggggagagcgctagtcttcgctgtgagaccacaacgccgggcgccggcgtc gtctggaggctcggcgacaggccgctggcgtccagcggcaagtatcacctgaaacaggaa ggaaccgtggtggagctcgccatctataaactgcagggggctgactcgggagaatactcc tgcgatacgggcgaccagaggacttcagctgtcctcaccgtgcaggaggtcgaggttaac atactgaacttcctggagagctgcgttgtgtacgagggagaagacgttcactttgaatgt cgggtttctcgcggggacgcgcctcaggctcagtggaagctccaggacgtcccgctgcag gataacgaaatgaacctgatcctgcgcgagggtcccgtgcacggcctcacgctcagaggc gtcacgccggctgactcgggaacagtcactttcacagtgggtaaccacacttccaccgct tctctgacagttagagccgcacctgtgctattcaagaaggagctggagagtcaagaggcc cgtgaaggagacgcggccaccctgtcctgtgagacctccagccccgactgccaggtgatc tggctgaagggctccacggtgctcacccacggagaaaagtacaacacggagcagagagcc agcactcacatcctggtcgtgcacaagctgaatgtgcaggacggtggagaatacacctgt gacacaggggggaggaaaagtacagctaccctgactgtgaaagagcatgtgcgcctcgtc cgggagctctgcgacctcaccgtggccaccgggcaggacgccgtcttcgaggtcgagttg tctcactccggcgtgacgcacggggaatggtggctcgcagacaacctccttcaaaataac gacctgaatcaaatgagcgtccggggcgcggtgcaccgtttggtcctgaagatggtgacc acggatgagtcgggggacgtcgccttcgtggtgggagaagagaagaccgtggcctgtctc ctggtggaggagaaacccaaagtgctaatactagagaggccccacgacactgtggcagta gagggtgaaaccgccacgctggcctgcaccgtctctgacgccaaggccgcagtcagctgg atcagaaacaacgtggccgtccaagccggcctcaagtacgagccgaggagcaacggggcc ttccgccagctttgtatccacaacctggtgcccgaggactcgggaacgtacacgtgtgac actggagatgcacagtgcggcgtcaccttgaccgtggaaggtgccccagtgttcttccgc aaagagctcaagaacctggacgccttagagggcgaggaggtcaccctgcgctgcgagccg tctaagccgggcgttcgtgttgagtggaggaaagggggcatggtcctccagcccggtaag aagtgcgagatgaggcaggaagggtgcgttcaagagctcgttttacggaacctggagcct gaggacagtggctactacacctgtgatgcaggagaccagctcaccacagcgtctttggcg gtgcaagtgaaagaagtcttcgtagtgtgtggtcttaagaccatcgacgtctttgttggg gagtgggcaaccttctcctgccagctgtctggtagggcacctgtccaggtgcagtggtgg ctggacggcaccttgctggagaacagcccctttagtgagatagagctgagcccgggccac atccacacgctcaccttaaagaacctggccacggacgactctggcactgtcgcgttcaaa gccggcagtttaacagcaacagcaaagctcttagtcaaagatcccacagtcgaagtggtg agcgagatggaggacctccgggtgcttaagaaccaaccggctgagttcatctgccagtac tcgcggccggtcacggctcagtggaagaaagacggccggccgttgcagcccgatggccga agggtgttagtggagcaggactggaacgtggcgcgcttgtacattagccacgcgtccgcc gaggacgcgggcgcatacgcctgcgaggcggaggggactcgcgtggtcgcttcactttac gtggaaggcaaacccattgaccttgtccagggcctggagaatgtggaaaccttcgacggc ggtgaagcgctgttcgagtgcgccctctcccgtcccgagagcaaagactgtcgctggctc ctcgacgggaaaccagtcaaggagtcccctaatgctgaaatcgtgacctttgagagcggc cgtcgtcacctgctgctgctgaaggagttgagagtgagcgacagctgcacggtgaccttc aaagctggcgcagcatccacatctgcccaactctctgtcaaaggctggcagctggatgtt gtgaagcctctggaggacaaggtggccgcagtgggagagaaggttgagttctgcgtcgag ctcaacgagcgggtccccgtggcggaagtcgcctggtacgccaacggcgttgagatcaag tccagcgacctctgggctatgagggccgacggatgttcttatcgcctcgtcctcaggcag gcgccgcttttgccgcagcaggaaattacgttcgctgcaagagatgccctctctctggcc aagctcaccatcatcactgtgtctgatcctccggaggacccggaggtcctcggtaagacg gaaaagtccgtcaccctctcttggttcactcctttacacgacggaggaagtcccatcctg ggctacagggtggagatgcggctgacggacagcgccctgtggcttccgagtcattctgaa cccgtgtgcaacacagagttcgtggttgagaacctcaccccggggagcggctacaggttt agagtggcagccatcaacagagccgggattggagagcccgttgagttgcctcagactgtg cagctgggtgtcgaggcaaaacagggagagcctgagacgatgggccaacccagtctgccc ccggaagcagctgaagaaggcgacgtccacgagctgtgggaggaaacggccaagaaacgg cgcatgagccgagagccgactctggactccatcacggagcaaccggaggaggtcgtgggt ggtcaaaataaatcggcgcagaaagattcgaagtcttccgagaaggtggaagttaaatcg gtcgagcgagcgcaggccaccgcgtccaagaagcagacggcgtccaagttgttgaccggc tcggaggacgagtctgttcccgggggttcgacgctcgtctcctacctcaagaagagcagc aagtcgaccgtcacagcgaccaatgaggccgaggccgaggccatttccaccgagaggttc tttgaacatttccagatggcagagaagagaaccgttgaaacgaccgcgattcagcagacg gacgcgaaaccggcgcccgcggaggagaccgacgtcatggagatcagcaaagaggacgag cccgagctcagggacgcggccattaagatccaagctgccttcaagggctacaaagcccgc aaggtcatgcgacccgtctttaaagacgccttcaaagaccagaccaaagaacccaacggc accattcatctcgaatgtgtggcggaaggcaaacccgataagatgcggtggctgaaggat ggagagccgctgcaggacggcaagcaccaccatattgatatctataacgacggcacctgc tcgctggtcatcaccgccatcgacacaaaggataccggcgtgtacacctgtgaggtcacc aacaagtacggagtcacttctcacagcggtaaggtcacagtgggcacggcgagagaatct tccgggcggcggccgctgaccgtgggctacagcgccgacagcgagcccgagagctcctcg gggagtgagatggacgagtcgctgaggcaggcgagcagacgtctccggcgcctgctgcgc acgcgcctcccgccggccgtcgaggaagagccgtttgtcagcgccgacgaaggagacctg tctcatccggacccgcactcctacagagaggacgacagctacatctacattcgcttcgac tcgcgggcggaggccgacgtggcctccaagaggttccagcagatgtttaccatccacggg gtgccggtggagaccaccatcctggaggcagggtttctcaaagtggagctgcgaatcaaa aagatgggctacacgcaggacggcacacagacccccacgccggatagacagcctcctgcc tttatggccggagcagcagccgccccggtcttcctgacagagctccacagtcaggatgtc cccgacggttatccggtcagcttcgactgcgtcgtgatcggcaagcccactcccgccgtt cactggtacaaggacggcaagctgctcgaggagaacgaccactacatgatcaacgaggac caggagggctgccaccaactcatcatcaccaccgtgctgcccaccgacatgggcgcgtat cgctgcaccgctgaaaacggcagcggcatcgcagccactaaggctgaactcagggtggac atgtcgtgcagctccgattacgacactgctgctgatgccactgagacgtcttcctatgtc agtgccaagggatacatgtccagggaaactgagacgtttgagtccgtggctgaagacgat cagcttccacaagttgtggacgagcttcacgacgttcatgtcagtccaggttcacctgtc gctaagatgcagctcaaattgaagggcttccccaaaccccgagtatactggttcaaagac agccaccctctgaggccttcagagaggatcctgttgctggcggagagagacgttcacgcc gtggagatcctgcaggtgaagaaagaggacatgggggagtactctgcttacatcagcaac gcagctggttccgcctactcctccggccgcctggtagttctgaatccgggggagatgatg ccacaagtcaaaagagaccccaaggtgcccctggtgccaccccgcttcctggaaaggttc agcaacaggaaggtgaagcaaggagccagcatcactctgtccgtcaaagtagaaggctcc cccactccgatggtctcgtggctgaaggaggaatcgatggaagacgtcctgtggatcaag cccgacaccaagggatacaaaatcgccagctcgggacgccagcacagcctcatcctgatg gacgtgggcacagaatacacgggcgcctacacctgcattgccaccaatagagcggggcag tccatctgcaccgcccacctcgaggtcgatgacgtaccacaaccaaagaagacctcagag gttcttggaattaccgttagcgctccagaggaggaggctggcagagcaaaagagattaaa ataccctacctcggtgaagtgggcacagaggaattcctcatgaaactcacctcccagatc actgagatggtatcggcgaagatgacgcaagacagcttacagaatcttgaagtgctccag tggatgaaatcttggcccaaaactaccacttccttgcgcgtaccaggcgacagcgacgat gagaccaagacgccttctccgtcgcctcatcacgggcgctctcgccctccctctctcatc gccgactcctcctccgagtccgacgagggggacgccagaggggagatgtttgacatctac gtggcgacggctgactacaaccccaccttagcgagcacagaagccatcgctctgaaggtg gggcagtacgtcgaggtgttggactctgctcaccccctcaaatggttagtccggaccaaa cccaccaaaacgacgccatcccgtcacggctgggtctcacctgcctacctggacaagaag ctcaaactctctgcggatacgagcgaccttccagagacaaacgtagaggaggtgtccgag ggggaatacaagaggaagttattccgactcatccaagacctgatgaagggtgaagccgag ttcgtgaaagagatggacttcttcacctcccaccacctgaagcacgccgacggccccgac gcaccgcccgacgtcagcagccagaaggaagccatattcaggaaccttgatgacatcaag tccttccacagcaaggcattccttccgaagctgaacgactgcgacacggacgacgacgta gccatgtgcttcctgaagaacaaggagggcttcgagaagtacctccactatctggtcggc cagagtctggctgaatgtgccgtcagcgacacggccgtccaccgcttcttcaaggagtac acggagaaagtgcaagccagtgcagaccctgcagaccccccagtacggagcatcaacgcc agcctccaacaaccactggagaggattcagaagtacaaggccgccctgaaggagctcatc cggaacaaggcgaaaaatggccagaactgctgcctgctggaagaggcgtacgccatggtg tctgcactgccccagcgctcggagaacacccaccacgtcaccatgatcgagaactaccct gccacgctggaggttttaggagagccgatgagacaggggcccttccaagtgtgggaaggg gctccgggaatcaggacgtcctctcgaggtcacaaccgccacgtgttcctgtttaagaac tactgcgtcatctgcaaagccaagagagacagcaacaccgacacgcaagcgtatgttttt aagaacatgatgaagctgaataacatcgacgtgaacgagacggtggagggcgacgaccgc gccttcgagatctggcacgagcgcgaggactctgtgaggaaatacaccttgcaggcccga accgtgaccatcaagaactcgtggctgagggacttcagagaactgcagcagcgatacagc acgcctgcgtggagtcctcctgactttgatgaaattctggcaaactgcacagcggagctg agacagacagtgaagctggcctgcaaagtcaccggcgtgcccaaaccagctgtcacgtgg tacaaggacggacgccccgtggaggccgatcctcatcacatcatcatcgaggatcccgat ggttcctgcacgctgatcttggacaacatgacggccgacgactccggccagtacatgtgc ttcgccacgagctcggccggcaacgccagcactctcggcaaggtcactgttcaagtgcct cctcgttttgtgaataaaatgaggaatgctatattcgttgctggggaggacactcagttc acctgcgtcatacagagcgcccccaaccccaagatcaggtggttcaaagattgccggctg ctgacggaccaggacaagtatcagacctacagcgagctccgcagcggagttctggtcttg gtgataaagaacctgaacgagagagacctcggacgctacgagtgcgagttgtgtaaccgt ctgggcagcgccaagtgcgccgcggatctcgtcccaccctccgctgtggctcgcactggt gagcaggccatcacgatcgaagttactgaacaggagacgaggataccaaagaaaaccatc atcatcgaggagacgataaccactgtggtgaagaaccaacgtatgaggaggcacaagtcc cccggcttcgccgtcgccggagcccaccgctcggagacctccaccccagaggcccccgcg gccaggccgaggaggatgcccacggcgagaaagagcgccatccccaccctctgcgtcacc gagcccggcggcgccgaagccagagccgcggagagcaagccccggtggatcgaggtggag gaggtcatcgagtacaaggtcaataagtcccccaggctgtccaggaggaggggcgtctcg ccggcggggtctgatcgcgccaccgctccctccagatctaaaagatctccgccggagaac ccgaacgcaaacaattccaacaacaatctggtggggcaggcccaggcccaggcccagctg caggcccaggcccagctgcagggcgacagccagccgctcccctgggaagaagaagaagaa gaagaggagggaggcgtcgcctccgactccggagagccgcgcgagatctcgtccgccctc acgccggcctgcgaagacggcgaggacccggacgacgatcaaaccgtcatctttgaaccc gacgatgaagacgaggatcgtgtctcgccgggggaacgggagcccgagtttctgacgcaa ggcggccgcgttttgaccctcgaagacctggaggattacgtcccggaagaaggcgagtcc tacggttcctccggcgcccacaagcccgccaaggaaaagccctgcgagatctccgtgctc cagagggagatcggcggctccacggtggggcagccggtgctcctcaacgtggggcggccc gtcgccgcccccaggcagaggagcggcggcttcttcagccgcttcagggagcacctctcg tccggcggcgttttctcaccggcggcgtcgtccccgcaagccagcggaggccagtcccgg acggagaggcgcgtccccatccaagtgagccacgccaagatcgaggtgaagccgtcgtac cgctcggaggtgcagagagtggagggcggccggcggagcttcagaaccaaagtgtcgacg cagaccttcggctacacgtcggtgggcaacccggtcacgctgcagatcagcgacgacctt cgtccggaccagtag

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