Cyclopterus lumpus (lumpfish): 117749018
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Entry
117749018 CDS
T09199
Symbol
erbb2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
clum
Cyclopterus lumpus (lumpfish)
Pathway
clum04010
MAPK signaling pathway
clum04012
ErbB signaling pathway
clum04020
Calcium signaling pathway
clum04510
Focal adhesion
clum04518
Integrin signaling
clum04520
Adherens junction
clum04530
Tight junction
Brite
KEGG Orthology (KO) [BR:
clum00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
117749018 (erbb2)
04012 ErbB signaling pathway
117749018 (erbb2)
04020 Calcium signaling pathway
117749018 (erbb2)
09133 Signaling molecules and interaction
04518 Integrin signaling
117749018 (erbb2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
117749018 (erbb2)
04520 Adherens junction
117749018 (erbb2)
04530 Tight junction
117749018 (erbb2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
clum01001
]
117749018 (erbb2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
clum04147
]
117749018 (erbb2)
04090 CD molecules [BR:
clum04090
]
117749018 (erbb2)
Enzymes [BR:
clum01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
117749018 (erbb2)
Protein kinases [BR:
clum01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
117749018 (erbb2)
Exosome [BR:
clum04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
117749018 (erbb2)
CD molecules [BR:
clum04090
]
Proteins
117749018 (erbb2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
ABC1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
117749018
NCBI-ProteinID:
XP_034415095
Ensembl:
ENSCLMG00005004004
LinkDB
All DBs
Position
19:9645620..9667303
Genome browser
AA seq
1303 aa
AA seq
DB search
MEAARSLVFVGAVLLWVAGASAREVCLGTDMKLTLPSSLDNHYETLKLLYTGCQVVHGNL
EITHLHGNPDLSFLQGIVEVQGYVLVAHVSVSLLPLDNLRIIRGSQLYDSSYALAVLDNT
LGGQGLRTLRLRGLTEILLGAVHIWGNPQLCFPDPQTIDWRDTLDVQNGHAGKHRLQPRA
SECPNCYSVCGKKCWGETAQDCQTLTRLPCAIGCQRCKGVLSNDCCHMQCAAGCTGPKDS
DCLACRHFNDSGVCKENCPPPTIYDPVTFQTKPNPNKKFNFGATCVKTCPYNYLAMEVAC
TLVCPRANQEVLIAHPDGDELQKCEKCEGDCPKMCYGLGMDNLGVMDNHGVTMVTSTNVE
QFNKCNKIFGSLAFLPQSFERDPVRNTSGLTIEQLSSFKKLEELTGYLYIDAWPEEWTNL
SVFESLKVIRGRMLYKGVFSLAIQNLHIRSLGLRSLRSVSGGLVLLHNNSQLCYTNALPW
NNLLHPTQGPHRIVNQNQDAQLCEEEGRVCHLLCEGGCWGPGPSQCVSCKAFQRGIECVE
QCDINQGSIREYTDGSLCVACHGECRPLNGSASCHGPGAEHCSECRNHQDGELCVDHCPS
GVKEDQQTVWKYSNATGHCLSCNTNCSLSCTVMDERGCPVDTRTGPGTTIAAAVGGVVLF
FILLALLVFYLRRQKNLKRKETMRRILQEHELVEPLTPSGASPNQAQMRILKETELKKLR
VLGAGAFGTVYKGVWAPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVASPYVCR
LLGICLTSTVQLVTQLMPYGCLLDYVRENKDRIGSQFLLNWCVQIAKGMSYLEEVRLVHR
DLAARNVLVKNPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILHRKFTHQSD
VWSYGVTVWELMTFGAKPYDMIPAREIPDVLEGGERLPQPLICTIDVYMIMVKCWMIDPD
SRPRFKDLVSDFSVMARDPPRYVVIQNDEQMSMSIPVDSQFFRMLLEEEGNNIRELLDAE
EYLVPQPNHFSRSQVDGAQANGPSRHQSYRQSRDQALEVESSVTGGPRSMYSSLSTLGRS
QYPTLPSGASTSNGIWIPQYPTLVRSPSAGSQSDSVFLDGSPDDPSLPPASPGRYSKDPT
YSNGSQGDLETDGPNGFHLPNHLHHSLPRRSHGYIHNHALPEYVNQEIKDLRPGIPERPT
TLPRKGSRADRRLPNGLCSGHSVENPRYLVPASAGAATSPAFDNPYYLDLVAKANAVAEA
AAVNGPEALERDGRVPRHVNGFVTPTAENPEYLGLADTWTGYT
NT seq
3912 nt
NT seq
+upstream
nt +downstream
nt
atggaggcggcgagaagtttggtgtttgtcggggccgtgctgctctgggtggcgggcgcg
tcggctagagaagtgtgcctgggtacagacatgaagctgaccctgccctccagtctggac
aatcactacgagaccttgaagctgctctacactggctgccaggtcgtccacggcaacctg
gagatcacacaccttcatggaaaccctgacctctccttcttacaaggcatcgtggaggta
cagggctatgtacttgtagctcatgtgtcagtgagtctgttgcctttggacaaccttcgc
atcataagaggcagccagctgtacgactccagctacgccctggctgtgctggataacact
ctgggtggacaggggctccggacactccggcttcgtggcctcacagagatcctgttgggt
gcggtgcatatttgggggaacccccagctgtgcttcccagacccccagaccattgattgg
agagacactttggacgtgcagaacggccacgccgggaagcaccgactgcagcctcgggcc
tctgaatgtccaaattgttactctgtatgtgggaaaaagtgctggggagaaactgcacag
gactgccagaccttgacccgtcttccatgtgcgattggctgccagcggtgcaaaggtgtg
ctctccaatgactgctgtcacatgcagtgtgctgctggatgcacaggacccaaagactca
gactgtctggcttgccgccacttcaacgacagcggcgtgtgtaaggagaactgtcctccc
cccacgatctacgaccccgtcacctttcagaccaaacccaacccaaacaagaagttcaac
tttggagccacctgcgtcaagacgtgtccttataactatctggctatggaagtggcttgt
actttggtttgtcccagagccaaccaggaagttctcatcgcccaccccgatggagacgag
ctgcagaaatgtgaaaagtgtgaaggagactgtcccaaaatgtgctatggtctgggtatg
gacaacctgggcgtcatggacaaccacggtgtcaccatggtcacatctactaatgtggag
cagttcaacaagtgtaataagatttttggtagtctggccttccttcctcagagctttgaa
agggaccctgtgagaaacacatcaggtctgaccatcgagcagctgagcagcttcaagaaa
ctggaagagttaacaggttatttgtacattgatgcctggccagaggagtggactaacctg
agtgtgtttgagagcctgaaggtgatcagaggcaggatgctctacaagggtgtgttttca
ctggccatccagaatctacacatccggtctcttgggttgcgttcactgcgcagcgtcagt
ggaggtttggtcctgttgcacaacaattcccagctgtgctacaccaatgcactgccctgg
aacaatctgctccatcccacccagggacctcaccgcatcgtcaaccagaaccaggacgcc
caactctgtgaggaagaagggcgtgtttgtcacctgctgtgcgaggggggctgctggggg
ccggggcccagccagtgtgtgtcctgcaaggctttccaacgcggcattgagtgcgtggag
cagtgtgacatcaatcaggggtctatccgtgaatacacagatggatctttgtgtgttgcc
tgccacggcgagtgtcgacctctcaatggctctgcttcctgtcatggcccgggggcagaa
cattgttcagagtgtcgaaaccatcaggacggggagctttgcgtggatcattgtcccagc
ggtgtgaaggaggatcagcaaactgtgtggaagtacagcaacgctacaggacactgtctg
tcctgcaacaccaactgctcgctgtcctgcactgtgatggatgagagaggctgccccgtg
gacaccaggacaggaccgggtacaactatcgcggctgcagtgggtggagtggtgctcttc
ttcatcctgctcgctctgctggtcttctatctgaggagacagaagaatctcaagaggaaa
gagacaatgagaaggatcctgcaagaacatgagcttgtggagcctctaacacccagtggt
gcgtcacccaatcaggctcagatgcgcatcctgaaggagactgagttaaagaaactcagg
gtgctgggtgcaggggcctttggtactgtttacaagggagtgtgggctcctgatggggaa
aatgtgaaaataccagtggccattaaggtgttacgagaaaacacctctccaaaggccaat
aaagagatccttgatgaggcctacgtgatggcaggagtggccagcccctatgtgtgccgt
ctgctggggatttgtctgacctccacggtgcagctggtcactcagttgatgccatacggc
tgcctcctcgactacgtcagggagaacaaggaccgcatcggctcccagttcctcctcaac
tggtgtgtccagatcgccaagggaatgagttatctggaggaagtccggctggtccacagg
gatttagctgcccgcaatgtgctggtgaagaacccgaaccacgtaaagatcaccgacttc
ggtctggcccgtctgctcgatatagacgagactgaatatcacgctgatggagggaaggtt
ccgattaaatggatggctctggagtctattctgcacaggaagttcactcatcagagtgac
gtctggagctacggtgtgacggtctgggagctgatgacgtttggggctaaaccctacgac
atgatcccagcgagggaaatcccagacgtcttagagggtggagaacggctcccccagccc
ctcatctgcaccatcgacgtctacatgatcatggtcaaatgttggatgattgacccagac
agcagaccacggttcaaagatcttgtaagcgattttagtgttatggccagagatccacct
cgctatgtcgtcattcagaacgatgagcagatgagcatgtccatcccagtggacagccag
tttttccggatgcttctggaggaggaagggaacaatataagggaactgctagatgctgag
gagtatcttgtgcctcagccgaaccacttctccaggagtcaggtagacggggctcaagcc
aacgggccgtccagacaccagtcatacaggcagagcagagatcaggctctagaggttgag
tcctctgtcaccggtgggcctcggagcatgtactcctccctgagcacccttggccgcagc
cagtaccctactttaccttcaggagcaagcacctccaatggcatatggattcctcagtac
ccaactctggttcgcagcccctcggccgggagccaatccgactcggtcttcctggacgga
tctccagacgacccctcgctgcccccggccagccccggacgctacagcaaagaccccacc
tactccaacgggagccagggtgacctggagacagatggaccaaatggctttcatcttcct
aatcaccttcatcactcgttgcccagacggagtcatgggtatattcacaatcatgccttg
ccagagtacgtcaaccaggaaattaaggatctcaggccggggattcccgagcggcccacc
acgctgcctcgtaagggctccagagccgaccgacgcctccctaacggcctgtgctccggt
cacagtgtggaaaacccgagatacttggtccctgcgagtgctggggccgccacttctcca
gcctttgacaacccttactacctggaccttgtggccaaagccaatgctgtagccgaggcg
gcagcagtgaatggtcctgaggcactggagagagacggaagagtgcccaggcacgtgaac
gggtttgtgacccccactgcagagaatccagagtatctgggactagcggacacctggact
ggatatacttga
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