Columba livia (rock pigeon): 102090542 Help Entry 102090542         CDS       T02912                                  Symbol SYNE1 Name (RefSeq) nesprin-1   KO K19326   nesprin-1 Organism clv  Columba livia (rock pigeon) Pathway clv04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:clv00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     102090542 (SYNE1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:clv03036]     102090542 (SYNE1) Chromosome and associated proteins [BR:clv03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     102090542 (SYNE1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 SYNE1 CH KASH ATG17_like Motif Other DBs NCBI-GeneID:  102090542 NCBI-ProteinID:  XP_021150564 LinkDB All DBs Position Unknown AA seq 8790 aa AA seqDB search MARYKGAGGRSVTSLNVRPRFFQYWHDEQESVQKRTFTKWINTHLAKRNPPMLVNDLFED IKDGVMLIALLEVLSGQKLPCEQGRQLKRIHWVANIGTALKFLEGRRSVYRGSPIKLVNI NSTDIADGRPSIVLGLVWTIILYFQIEELTSNLPQLQSLSSSASSVESVVSSETASPPSK RKVVTKVQGSARKALLKWIQYTAAKQVGIEIKDFGQSWRSGVAFHSIIHAIRPDLVDMEK VRGRSNRENLEEAFTLAEAELGIPRLLDPEDVDVDKPDEKSVMTYVAQFLKYYPDPHHTV TDVQDNEKEDRLMLRDLKVWAEQFERDLVRAQVAETSLQEKYQSFKHFRVQYEVKRKQIE LVTQSLRKDGKLSLDQAMVKQAWDRVSSRLLDWHIHLDKSLPAPLGTIGAWLHRAEAALR EEVTVQQAHEETANTIHRKLEQHKDLLKNIDAHKKAFHEIHRARSVNGVPVPPDQLEDMA ERFNFVVSSSELHLLKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVELLLQNYISV IENSKFFEQYEVTYQILKRAAEMYAKANGSVEEVENVMKFMNDTTAQWRNLSVEVRSVRS MLEEVIANWDRYSSTVAGLQAWLEDAEKMLNQPEHSKKDFFRHLPHWIQQHTAMNDAGNF LIETCDETISRDLKQQLLLLNGRWRELFMQVKQYARADELDKMRKEYLDGVAHLTAFIDG SNKKLSAPVEVSFLEVKMFVQELENIKQKLPAMETQYKMLTRTTQLVTKEVSQEEVNEML GTLTRIKEQLSKVKEYSCALLYECQHLLSPLEELEKQITHFYESLEKVNEIISILDPEAQ PTTVLKQKAQDLVAYQENCKKDLSLIERNSQSILQCVASSEVLQHFHQSTFQKKVTQVQI TFQNMVRKAGDWRKNIEANSRLMKKFEESRAELEKVIQIANCCLKEKGNPEELLRKHSEF FNQLDQRVLNAFLKACDELTDILPEQEQHNLQEAVRKLHRQWKDLQTEAPYHLIHLKIEV QKSKFLVTVEECKAELARQNKVLSREDNERMIKEHVLFFGDKGPYHLCEKRLQRIEELCQ KLPVSDPVRATLESSHRILKDLKSQIDSTYIKLTERSDTWKGYKSRFSELANWISSTERE LKKIKGNVSDTAKYQQFKASVGEIRKRINKQRENHSWLKSRLAVLIELCPDVEAKRTEDE LCKLSSDFKGLLDLLAEIEKTLGTVGDCVQYKEEVKSAIEELINNSKEAQAEAEKILDTE SLLQAQQLLLHHQQRTRRLRAKRQDVQQQISQAKQLQIEGGLPSTMQEDLQKLEGTLENM QQTMEKREEQLQVTINKWEQFERDKETVVKYLNQASSALERILNFSSLESLSSELDQTKE LSKQTEAMAVQAENLVKSSSEIQLGSKNKQSLQQQAKSIQEQVKKVEVTLEEDIKSMEMV KNKWDHFGNNFEALSIWIAEQEKELETLETSSSPLDMQISHIKVIHKEIDGKITGISSLE EEAESLSQFITSGECAHIKAKLTQVKRYWEELRDHAQRLEATVAGNASAQQKYEESLKQV QQTVSEFEAKLVEPLTSCSSSSATYAALQDCTDLYHTVEKLSNTLASLSGCARKVVNKEE AVQKVTALQQKYEKVLGNAKEKQTLLETLLAQWQKQEKELSIFLTWLEACEAMARPSEQY VSADRVKLEGELQSLRDLQEDIESHASVYARLLQLSESLFPTASKQCVKTMKEKFEELDE RWKALPQTLDKRINFLQSLIAEHGQFDELLLSFSDWIKQFLAELQATSEINTTDQQLAAS HNKKHAMEVESKKEQLRSLKEHVNKLCSFSCPEDQQTFQGKTEDCFQIFQEASQITSQRQ EALDQLQVFLELHSSASGVLHQLRQRVEKTGNMDKTKSELLEKELNDVIQALNKLESVAI SLDGSLTKAQYHLKHGMSEQRTSCRAVVENLCLELDAVQNLLGTKQSEAEALGALRRSFM ERKEQLLKSIEDTEEKADKEGLKEATLQALQQRLRLFNQLDEELNSHQHELQWLMDKAKQ IAQKDITLAPEIDEEINRLESLWEDTKKVIHEKKEQSCILIDLMKEYQSLKSTVTKVIDS AGSASVIKSISKDHEDVRRTLSKHEAAKNDLSDKQKDLDTFTNKGKHLLTELKRVHNCDF SAIKADMNCTVDKWLDVSERIDDNIDRLSVCVSLWDDILKSGDEMDGWCNKCISQLNEGI SNLSNSQRMEILLKDLQSEVKDKELKLEQLSSKISDLKELTHSQEPPADLQFIASDLRQK LEHAKEMLQTAKETLKDFSTRKMELQRFVDQMTDWLAKVEETLLSCARNLDSEALNKVKE TEKDLQLQQSSIDLTRENLNSLCRKYHSVELETLGGTVTLLIKKYESLNQLCSRTQASMQ ESLEKHFLYSMQEFLEWFSGAKAAVKESSYRSGDSKAIEAKLHDLQGVLDSVSEGQKKLD AACKEGESLCACLPERVVSHIQEQIAKSNQNFQEFLNQCLNDKQALEACASHLGTFEDQH KKLGLWIHDMEERINTEALGESKQLIPEKKKEVQKVEKFLEELLNSRESFDKLSQMAQTL NEEGHGVGNEMRLASQHLTNYQNMVKTVREKLRTCQLALQEHLTLEEALQSMWSWVKEVQ DKLTSSESTVGSKATLERRLTQIQEILLLKGDGEVKLNMAIGKGEQALRSSNEEGQKVIQ NELQTLKDVWNDIISTSVNWQSCLESVIGQWNEYLERKNQLEQWLEKLDHKVEQPLEPQL GLKEKFAQLDHFQAIVSEIEDHSGDLQQLTEKAVELYEKTEDDSFGEAAQEELKTQFNDI RTVAKEKMRKVEDIVKDHLLYLDAVHEFTDWLHSAKEELHRWSDTSGDTSTIQKKLAKIN PAGGCQLLAAEMQALRSDWRQWEESALRSQGSLREVLSQMALSEREFAERVAQLEEAVQR FGGLLAAWSQSLVPLDSRHTDAEVVESWRKEKETLDALVKSEHMTDEIKTQLNDLCRFSR DLSTHSSKVSGLIKEYNSLCLQASKGCQSKEQILQQRFRTAFRDFQQWLVNAKVTTAKCF DVPQNISEASASLQKIQEFLSESENGQQKVNLLASKGELLCSVLPKEKAKVVRDKSATAK EDWKNFITILHQKESTLENLKIQMKDFEATAEPLQEWLTTTEKMVQGSSGRLHDLPSKRR EQQKLQSVLEEISCHEHQLNRLKEKAQQLWEEQAVSKSFMRRVSQLSSQYLTLSNLTKEK VSRMDRVVAEHQQFSHSVKDLQDWMADAVHMLDSYCHPTADKSVLDSRMLKLEGLLAVKQ EKEIQMKMVLTRGESVLQNTSLEGVPVIEKQLQTLKDSWASLLSACIQCKSQLEGALSKW TSYQDDVRQFSSWMDKVEASMNASERQYAELREKTAALSKAKLLSEEVLSHSSLLETIEV KGSGMAEHYVTQLELQDLQERYKFLKDRTREAVTKTEELLSLHQKYQRNLKAFELWLEKE QEKLDCLSHLDGDAQKQEATLRDLQELQVHCVEGQALLNTAVHAREEVIPWGVPQIEERA LESLRQDWQVYQHRLSEARSRLNATVSRLRLMEKKFQKVIDWLTGLEDKVAIRSGRQSGR ATKEIQLQQMKKWHEEITIYKDDVEEVGVLAQQILEESLTASRMGSQATQLTSRYQTLLL HVLEQIKFLEEEIRCIDESELAFSAYTNWYEATNKNFRTVITKVDVVDKTAMEKKVQKLE LLLSDMDIGHSLLKSAREKGQRAIKYMEENEVDQLRKEIEDHVEQLEELAGSIRKEHMTS EKCLQLAKEFSDKFKAQTQWLMEYQAMLQAPAEPKSELYEKKAQLSKYKSIQQTILSHEP SIKSVIEKGEALFDLVNDVTLKNSIQDLENSYQELCTTTKACVENLEVRVKEHEDYNSDL QEGEKWLLHMSSRLVSPDPIESNNLEIITQQLANHKAIMEEIAGFEDRLNNLKSKGDYLI NQCTEHLQAKFKQNIQSHLQGTKDSYSAICSTAQRVYQSLEHELQKHVSHQDTLQQCQAW LSTVQSELKPATWPPFSLADAVKQVKHFRALQEQANTYLDLLCSMCDLSDTTVKSTAADI QQTKQMIEQQIMHSQYLAQGWEEIRQIKADLWIYFQDADQQLQNLKRRRAELELNIAQNM VLQVKEFSQKLQSKQSALTSVTEKMNKLTQGQESPEHKEIGELSNQWLDLCLQAHSLLIQ REEDLQRTGDYHDRMNVVEVFLEKLTKEWDNLARSDAESTNVHLEALQKLALALQERRFA LEDLKDQKQKMIEHLNLDDKELVKEQFSHFEQRWTQLEDLVKRKIQVSVSTLEELSLVHS KFQELMEWAEEQQPSISEALKQSPPPDLAQSLLMDHLTICSELEAKQLVLKMLVKDADRV MTNLGLNERHELQKALSDAQHHVDCLSNLVGQRRKHLNKALSEKTQFLMAVFQATNQIHQ HEKKVMFPEHICLLPEDVNKQIRTCKNAQANLKAYQNEVTGLWAQGRDLMKEATEQEKSE VLGKLQELQNMYDTVLQKCNQRLLELEKNIVSRKYFKEDLDKACHWLKQADIVTFPEVNV MNSNSELYTQLAKYQQILEQSPEYENLLLGLQRDGQEILPSLNEVDHSYLDEKLNVLPQQ FSIITALAKEKLYKVQEAIHARKEYASLIELTNKALTELEDQFMNMDKAPAAVLAKEAVS LQQTYRDLLGEVMSLGTAVEELNQKKEAFRSTGQPWQPDEMLKLITLYHKLKRQIEQKIN LLEDTVEACQEHEKMCMQFEAQLEAVKKEQVKVNEETLPIEEKLKIYHSLVGSLQDSGSL LKRITEHLEALSPQIGSSACAAANHQVQSWQEKLKSLHAAIGDTVMECENRLVQSIDFQT EIRRSLDWLRWVKTELNGTLSLDLKLQSIQEEIRKVQIHQEEVQSSLRIMNALSNKEKER YMKAKELIPADLENTLAELTELDGEVQEAIHVRQATLNKLYNLCQRYYQVMQMTNDWLED SQEFLHLARNGLDVENSEENLRNHIEFFSTESQFSNHLKELQGLLSEIEPSIQATAREQL VQNVAALEEKAKETKQEAKTQQEQLQRCASEWQEYQTARQKVIEVMNEAEKKLSEFSVAK AASSHEAEEKLLTHKTLVSVVNSFHEKITTLEEKALQLEKISNDASKATISRSMTTVWQR WTRLRNVAQEQEKILEDAVQEWKGFNDKIQKATIAIDQLQGRLPESSVEKASKTELLELL DYHGTFLLEVEHQLSSLGLLKQQAVSMLQDVEIKPLSQEELPVIQEIKAMQDRCYNMQQK VKKGVKMVKQELKEREEVEAEINSVKSWIQETKEYLLSPDVEVDTQLQELQSLLGEVTTH RQAVEKMAEQQQNKYLGLYTVLPSELSLHLAEVGLALVTVQDQIQTKEKEAQQIKTLNQE FGQKIQGIANELNAILSKLKRKTNDIAQAKLEQKILGEELDSCNIKLLELDASVQDFAEQ NAPLAKQLANRIGKLTVLHQQTIRQAECRAAKLSQAASHLEEYNEMLEFILKWIEKANIL VHGSITWNSSSQLCDQLKAYQAMLDESGEIHGDLEAMNERTEYLASVYCTEEMSQQVVEL GRRTEELQQVIKVRLPNLQDAAKDMKRFEVELRALQAALEQAQATLTSPELGHLSLKEQL SHRQHLLSEMESLKPKVQAVQACQSALRIPEEVVTGLPLCHSALRLQEEASRLQHAAIQQ CNIMQEAVVQYEQYEQEMKHLQQMIESAHREIQDKPIATSNIQELQVQISRHEELAQKIK GYQEQIAALNSKCKMLTMKAKHATMLLTVTEVEGLSEGMEELDSDLLPGHPAHPSVVMMT AGRCHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTDASVNQDIAYYQALSAEQLQT EAAKIQPSTSATQEFYESGLESAASAKLDDLQRSWETLKNVISEKQRTLYEALERQQKYQ DTLQSISTKMETTEIKLNESLEPAKSPESQMAEHQALMDEILMLQEEITELQTSLAQELV SEPLDAEAADQLALQSTLTVLAERMATIRMKASGKRQLLEEKLNEQLEEQRQEQALQRYR CEADELDHWLLNTRATLDTALVTAEEPMDMEAQLVDCQNMLVEIEQKVVALSELSVHNEN LLMEGKAHTKDEAEQLAVKLRTLKSSLLELQRVLHDKQINIRQSSLQEKEESDLDFVSSQ SPSVQEWLAQARTTRSQQQQNTLQQQKELEQELEEQKNLLRLVACRGEEILTQQGAPEGL CLSEKPNTLSEELGLEGEKPSSEEQMKVKWESLNQEFNTKQRLLQKTLEQEQPQFYSRPN RLISGMPLYQEEGQGADKSIVSPVLVELNQAFEDVSPEAGQVEQSLHLEQKLYDGVTATS LWLDDVEEQVFVATALLPEKETETYLCKQESLAKEIKDITEEMDKNKNLFTQIFPENCDY RDIIEDTLNCLLRRLTLLESVVNQRCHHMKGQLQQIVTFKNDLKVLFTSVADNKYLVLQK LAEAAERPETEQMQVILQAEEGLKELDAGINELKKRVDKLQIDQPSVQELSKIQDKYDEL MMIIGSRRSDLNQNLALKRQYERALQDLADLVETGQEKMAGDQKMIVVSKEEVQALLDKH KEYFQGLESHMILTETLFRKMSSFSLLKDTRSHSELMTQASAILKLAHKRGVELEYILET WIHLDEDYQELTRQLESVESSIPTVGLVEETEDKLTDRITLFQHLRFNLTEHQPKLYQVL DDGKRLLFSVSCSDLESQLNQLGERWLNNTSMVTKELHRLETILKHWTRYQSESNELTHW LQSAKERLEFWSQQSLMVPQELETVRDQLNSFLEFSKEVDAKSSQKSSVLSIGNQLLRLK KVDTAALRAGLSHIDSQWTELLTQIPAVQEKLHQLQMDKIPSRHAITEVMSWISLMENVI HQDEENIKNVVGQQVIQDYVRKYKGFKIDLNCKQLTVDFVNQSVLQISSQDVESKRSDKT DFAEQLGAMNRRWQILQGLITEKIQLLEGLQESWTEYENNVQCLKTWLETQEKKLKQQQL IGDQASVQNALKDCQELEESIRTKEKEVENVEQSGLSLIQNKKEEVSSAVMNTLQEINHS WANLDHMVSQLKTLLQSVLDQWSIYKVAYEELNSYLTEARYSLSRFCLLTGSLEAVKVQV DNLQSLQEELEKQESSLQKFGSVTNLLLKECHLPVTETLTNTLKEVNMRWNNLLQEIAER LRASKGLLQLWQRYKDCYQQCSSTVHQREAQTNELLKTATSKDIADDEVTTWIQDCNDVL TDLKTAQESLVVLQELGEELKSQVEASAAAAIQSDQLSLSQNLSTLEQALRKQQAVLQAG VLDYQTFAKNLQVLEGWITEAEEILKGQDPSHSSDLSEIQSRMEELKSQMLKFSSMTPDL DRLNELGYRLPLNDKEIKRMQNLNRHWSLISSQTTERFSKLQSFLLQQQTFLEKCETWMD LLVQTEQKLGAEISGNYQSLLEQQRAHELFQAEMFSRQQILHSIISDGQHLLEQGQVDDR DEFNLKLTLLSNQWQGVIRRAQQRRGIIDSQIHQWQRYREMAEKLCKWLVEIPCQPASTL GIVPIPLQQARALLDEVQLKEKGLLRQQGSYILTVEAGKQLLLSADSGAEAALQAELTEI QERWKKASTQLEQQKKQLALLLKDWEKSEKGIGDSLEKLRSFKKKLSQPLPEHHDELHAE QIRCKELENAVEGWTDDLAHLSLLKETLSVYISADDLSILSERIELLHRQWEELCHQVSL RRQQVSERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIEEMIEKLKKDYQEEIAVAQ KNKIQLQQMGERLAKASHESKASEIEYKLGKINDRWQHLLDLIAARVKKLKETLVAVQQL DKNMSSLRSWLAHIESELSKPIVYETCDSEEIQRKLNEQQELQKDIEKHSTGVASVLNLC EVLLHDCDACATEAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSR FEDWLKNSERTAAFPSSSGVLYTVAKEELKKFEAFQRQVHESLTQLELINKQYRRLAREN RTDSDCSLKQMVHEGNQRWDDLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQ LTNIEHFSECDVQAKIKQLKAFQQEISLNNNKIEQVIVQGEQLIEKSEPMDAAVIEEELD ELRRYCQEVFGRVERYHKKLIHLPLTDDEHDLSDREVDLDESADLSDIHWHDKSADSVLS PHPSSNLSLPLSQPVRSERSGRDTPASVDSIPLEWDHDYDLSRDLETAVSRALHSEEEDG GQEKDFYLRGAAGISDVEIPETLEAYVTLTENALKNISGEPGALEAHIRQLDKALDTSRF QIQQTENIIRSKTPTGPELDSSYKGYMKLLSECSGSIDSVRRLGYKLKEEEEKLSGLINL NSTETQTAGVIERWELIQAQALSKELRMKQKLQQWQQFNSDLNNVWVWLGETEEELEKLH HLDLSTDIQTIELRIKKLKEMQKAIDNRKAIILSINLCSSEFTQSDSEESKKLQEHLSQM NVRWDHVCSMIEEWRSSLQDALMQCQDFHEMSHGLLLWLENIDRRKNEIVPINPNLDSEI LQDHHRLLMQIRRELLESQLKVALLQDMSCQLLVNAEGKDCLEAKEKVHVIGNRLKILLK EVTHHIKDLEKILDISSSQLELSSWSSADELDTSGSVSPVSGRSTPSRQRTPRGKCSLSQ PGPSVSSPHSRSTRGGSGSSPSEAGPAWQRPSFFLRVLRVALALQLLLLLLIGLACLVPM TEEDYSCTMANNFARSFHPMLKYTNGPPPL NT seq 26373 nt NT seq  +upstreamnt  +downstreamnt atggctcgctacaaaggtgctggtggcagaagtgttacatctttaaatgtgcgtccaagg ttctttcagtactggcacgatgagcaagagtcagtacagaaaaggactttcacaaaatgg attaatactcacctggctaagcgcaatcctcccatgctggtgaatgatctgtttgaagat atcaaagatggtgtaatgctcattgcccttttggaagttctttcagggcagaaactgcct tgtgagcagggacgtcagctgaagagaattcactgggttgccaacattggcacagctctg aagtttctagaaggaagacggtctgtatacagaggatctccgattaaacttgtcaacata aactcaactgatattgctgatggcaggccttctattgtacttggcttggtgtggaccatc attttatattttcagattgaagagcttaccagcaacctcccacagctgcagtcattgtct agcagcgcttcttctgtggagagcgttgtcagttcagaaactgcgagtcccccaagcaaa cggaaggtggtaaccaaggtccaaggaagtgccaggaaggctttgttaaaatggatacag tacacagcagcaaagcaagttggaattgaaataaaagattttggacaaagctggaggagt ggtgttgcatttcattccattattcatgctattcggccagatttagtggacatggagaaa gtgaggggaaggtcgaatagagaaaacctggaagaagctttcacacttgcagaagcagaa ctaggaattccaaggctccttgatccagaagatgtggatgttgacaagccagatgaaaag tctgtcatgacctatgtagcacagtttttgaagtactatcctgatcctcatcatacagtg actgatgtgcaggacaatgagaaggaagacagattgatgctgagagacctcaaagtgtgg gcagaacaatttgaaagagatttagtccgagcacaggtggcagaaacgagcttacaggaa aaataccagtcttttaagcatttcagagtacagtatgaggtaaaaaggaaacagattgaa cttgtaacccagtcgttaaggaaagatggtaaattatcacttgatcaagctatggtgaag caagcatgggacagagtttcttccaggctactcgattggcacatacaccttgataaatct cttcctgcacctctgggtaccataggtgcttggctccatagagcagaggctgctctgagg gaagaagtaactgttcagcaagctcatgaggaaacggcgaatacaatacaccggaagctt gaacagcataaggatctgctgaaaaacatagatgctcacaaaaaggcattccatgagatc cacagggccaggtctgttaacggagtgcctgttccacctgaccaattagaggatatggca gagaggtttaattttgttgtctcttcatctgagctccatctgttgaagatggagtttctg gaactgaagtaccgtctactgtcactcttagtccttgcagaatcaaagttaaaatcatgg attatcaaatacggaaggcgagagtcggtggaactactacttcaaaattatatttctgtt attgaaaatagtaagttctttgagcagtatgaagttacttaccagatcttgaaaagagca gctgaaatgtatgccaaagcaaatggctcagtggaagaagttgagaatgtgatgaaattc atgaatgacacaacagcacagtggaggaacctctctgtagaggtgagaagtgtaagaagc atgttggaagaagtaattgctaattgggacagatatagcagcactgtggcaggtctacag gcttggctggaagatgctgaaaaaatgctgaatcaacctgaacattctaaaaaggatttc ttccggcatttacctcattggatccaacagcacacagccatgaatgatgctggtaatttt ctaattgaaacatgtgatgagaccatttccagagacctcaaacagcagctcctgttactt aatggaagatggagagaattgtttatgcaagttaagcagtatgctcgagcagatgaacta gacaaaatgaggaaggaatacttggatggtgttgcccatttgacagcttttattgatgga agcaataagaaactttcagcccctgtagaagtgtctttccttgaagtcaaaatgtttgta caagagttagaaaatattaagcagaaattgcctgcaatggaaactcagtacaaaatgctt acaagaacaactcaacttgttacaaaagaagtttcccaagaggaagtgaatgaaatgctt ggaactttgacaaggatcaaagagcagctgagcaaggttaaggagtattcctgtgccctg ctgtatgaatgccaacatctgctgtctccactggaagaactggagaaacaaatcacgcat ttttatgaatctcttgaaaaagtcaatgaaattatttctatcctggatcctgaagcacaa cctacaactgttcttaaacaaaaagcccaagatttggtagcttatcaagaaaactgcaag aaggatttgtccttgattgagagaaatagtcagagtatcctgcagtgtgtggcttctagt gaagtgttacagcatttccatcagtcaacatttcagaagaaagttacacaagttcagatc acttttcagaatatggtcaggaaagctggtgactggagaaaaaacatagaagcaaatagc cgtttgatgaagaaatttgaggagtctagagcagaactggagaaagtaatacaaattgcc aattgttgcttaaaagaaaaaggaaatcctgaagaacttctcaggaaacatagcgaattc ttcaaccagttggatcagagagtcttaaatgcctttctgaaagcatgtgatgaacttact gacattctcccagaacaagagcaacacaacctgcaggaagctgtgcgaaaactccataga cagtggaaggatcttcaaacagaagccccataccacttgatccacttgaagattgaagta cagaaaagcaagttcttggttacagtagaagagtgcaaagctgaattagctcgacagaac aaggtgttatcaagagaagacaatgaaagaatgatcaaggaacacgtgttgttctttggt gacaagggaccttatcatctgtgtgagaaaaggctacaacgaattgaagaactgtgccaa aaactgccagtttctgatccagtgagggctacgttggaaagcagccaccgaatcctgaag gacctcaaatcccagatagacagcacatacataaaactaacggagcgctcggacacctgg aagggctataagagcagattttctgaattggcaaattggatttcgtcaacagaaagagag ctaaagaagataaagggaaatgtcagtgatactgccaaataccagcaatttaaagcatct gtgggggaaattaggaagcgtattaacaagcaaagagaaaatcacagctggttgaaatct agacttgctgttttgattgaattatgtcctgatgtggaggccaaaaggacagaggatgag ctttgtaaactttccagtgacttcaagggactcctggatttgctggctgagattgaaaaa acattaggcactgttggagactgtgtccagtacaaagaagaagttaaaagtgcaattgaa gagttaatcaataactctaaagaagcccaagcagaagctgaaaagatcctggatacagag agtttattacaagcacagcaactactacttcatcatcagcaaaggacaaggagactccgt gcgaagaggcaagatgtgcaacagcagatttcccaagctaaacagctgcagattgaaggt ggactgcccagcacaatgcaagaagatttacagaagttggaaggaacattggagaacatg cagcagactatggagaaacgtgaagagcaactgcaggtcacaataaataaatgggagcag tttgaaagagacaaagaaacagtagtaaaatatctcaatcaagcaagctctgcacttgaa cgtatcttaaacttcagcagtttagagagcctctcatcagaactggatcagacaaaggaa ctttctaaacagactgaagcaatggcagtgcaggctgagaatctggtgaagagttcttct gagatacagcttggttcaaagaacaagcagtcccttcagcagcaggcaaaatcaatccaa gaacaagtgaaaaaagtggaagttactcttgaagaagatattaaaagcatggaaatggtg aaaaacaagtgggatcattttggcaataattttgaagctctgtccatctggatagctgaa caagagaaagaactggaaactctggaaacatcatcatctcctttggacatgcagatcagc catatcaaggttattcataaagaaatagatggtaaaataactggaatctcaagtctagaa gaggaagccgagtctctttcccagtttattacctctggagaatgtgcacatattaaagcc aaactgactcaggtcaaaaggtattgggaggagctaagagatcatgcacagaggctggaa 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caggtggaacagagcctgcatcttgaacagaagctgtatgatggtgtcacagccacctcc ttgtggctagatgatgtggaagagcaggtctttgttgctacagctctgttgccggagaaa gaaacagaaacatacctctgcaagcaagagtctcttgctaaagaaatcaaagacataaca gaagaaatggacaagaacaagaatttatttactcagatatttcctgagaattgtgattat agggacattatagaagacactttaaattgtctccttagaagactgaccttattggagtca gtagtaaaccagagatgccatcacatgaaaggacagctccagcaaatagtgactttcaag aatgatctgaaggtcctgtttacatcggtggctgataacaaatacttagttctgcagaaa ctagcagaggcagctgagaggccagaaacagaacaaatgcaggtcatactgcaggcagaa gaaggtttgaaggaactagatgctggaatcaatgaattaaagaagcgtgtggacaagcta caaattgaccaaccttctgtgcaagagctgtctaagatccaggataagtatgatgagctg atgatgatcataggatccagacggagtgacctgaatcagaatctggctcttaagaggcaa tatgaacgggctttgcaggacctggctgacctggtagaaacaggccaagaaaagatggct ggtgaccagaaaatgattgttgtttctaaggaagaggttcaggctctacttgacaaacat aaggaatattttcaggggttggagtctcacatgatcctgacggaaacgctctttaggaag atgagtagcttttccctcttgaaggacactcggtcacattcagagctaatgacacaagct tcagctatattaaagctggctcataaacggggtgtggagctggaatacattctagagacc tggattcatctggatgaagattaccaggaacttaccagacagctggagtctgttgaaagc agcatccccactgttggtttggtggaagagacagaggacaagcttaccgaccggattaca ctttttcagcatctgagatttaacctgactgaacaccaacctaaattataccaagtgctg gatgatgggaaaaggcttcttttttctgtcagctgctcagatcttgaaagtcaactaaac cagctaggagaacgctggttaaataataccagcatggttaccaaggagcttcacaggctg gagacaatactaaagcactggacaaggtatcaaagtgaatcaaatgaactgacacattgg ttacaatctgcaaaggagcgacttgagttttggagccagcaatctttgatggttcctcag gaactggaaacagtccgagaccaactgaactcctttttggagttttcaaaagaagtggat gctaaatcatcacagaaatcttctgttctgagtattgggaaccagctcctcaggctgaag aaggtggatacagcagcattgcgtgcaggattgtcccacattgacagtcagtggacagaa ctgctcacacaaatcccagcagtacaagagaaattgcaccagcttcagatggacaaaatt ccttctcgccatgctatcactgaagttatgagttggatttccctgatggaaaatgtcatt catcaggatgaagagaatataaaaaatgtagtaggacagcaagtcattcaggattatgtc cggaagtacaagggtttcaagatagatttaaattgcaaacaattgacggtggactttgtg aaccaatcagtgctacaaattagcagccaggatgttgaaagtaaacgtagcgacaaaact gattttgcagaacagctcggagcaatgaacagacgttggcagatcctgcaaggcctgata 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cagaatctgtcaaccctagagcaggctctccgcaagcaacaggctgtacttcaggctgga gtgctggattatcaaacctttgccaagaacctgcaagtccttgagggctggataacagaa gcagaagaaatcttgaaaggacaggatcccagtcattcatctgacctctcagaaatacag agtaggatggaggaactcaagagtcagatgttgaagttcagcagcatgaccccagatttg gaccgtcttaacgagctgggttacaggctccctctgaatgacaaagaaatcaaaaggatg cagaacctgaacagacattggtctctgatctcatctcagactacggagagattcagtaag ctgcagtctttcttgctgcagcagcagaccttcttggagaaatgtgaaacttggatggat ttattagttcagactgagcagaagttgggagcagagatttcaggaaactaccagagtctt ttagagcaacagagggcacatgagctcttccaggcagagatgttcagccgccagcagatt ttgcattcaattatctcggatgggcagcacctcctagaacaaggacaggtggatgacagg gatgaatttaatctgaagctaactcttctaagtaatcaatggcaaggggtaattcgccgg gcacagcagaggagggggatcattgacagccagattcaccagtggcaacgctacagggag atggcagagaagctgtgcaaatggctggtggaaataccctgtcagccagcgagtacactg ggcatcgttccgatcccattgcagcaagccagagccctactggatgaagtgcagcttaaa gagaaaggtctgctaaggcagcaagggagttatatcctcactgtggaagctgggaagcaa ctgctgctctctgctgacagtggggctgaggcagccctgcaggcagagctcactgaaatt 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