Columba livia (rock pigeon): 102090846
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Entry
102090846 CDS
T02912
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X2
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
clv
Columba livia (rock pigeon)
Pathway
clv00270
Cysteine and methionine metabolism
clv00480
Glutathione metabolism
clv01100
Metabolic pathways
clv01240
Biosynthesis of cofactors
clv04216
Ferroptosis
Module
clv_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
clv00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
102090846 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
102090846 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
102090846 (GCLC)
Enzymes [BR:
clv01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
102090846 (GCLC)
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Paralog
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Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
102090846
NCBI-ProteinID:
XP_005506836
UniProt:
A0A2I0MVH1
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All DBs
Position
Unknown
AA seq
587 aa
AA seq
DB search
MVEYMLVKFDHENKKVRLLLCGEEILQTLQDKGEKVNPNHPTLWRPEYGSYMIEGTPGQP
YGGTMSEFNTVQDNMRKRRQEAASVLKENEAVCTVTSFPRLGCPGFTLPEHKPTPVEGGA
SKSLFFPDEAINKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPNDDGEAA
KAAKPDYIYMDAMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRG
YVSDIDCRWGVISASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDL
TIDKDIYEHLIKEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQT
MRFKPPPPNSDIGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDE
NMKMAQKRDAVRQGMFYFRKDICKGGNALVDGCGSAQNGTGTDTEEYALMSIDTIINGKE
GVFPGLIPILNSYLESMEVDVDTRCTILNYLKLIKKRASGELMTVARWMREFIAQHPDYK
QDSVITDEMNYSLIWRCNQIAQGQAECPELLGVGFNKKQSGNKTGSL
NT seq
1764 nt
NT seq
+upstream
nt +downstream
nt
atggtggaatatatgttagtaaaatttgaccatgagaataagaaagtgcgcttgttgctc
tgcggtgaagaaattcttcaaacactgcaagacaagggggagaaggtaaaccccaaccac
ccaacactctggcgaccagagtatggaagctatatgattgaagggacgcctgggcagccg
tatgggggaaccatgtctgaattcaacaccgtgcaagacaacatgaggaaaaggcggcaa
gaggccgcttctgtgctcaaagaaaatgaggctgtttgcactgtgacatcatttccaagg
ttagggtgtcctgggtttacgctgccagaacataagccaacgccggtagaaggaggagct
tcaaaatccctcttttttccagatgaagcaatcaataaacatcctagatttagtacactg
accagaaacattcggcaccgaagaggagagaaggttgtgataaatgtaccaatatttaaa
gacaagaacacaccatcaccatttattgaaacatttcctaacgatgatggagaagcagca
aaggcagctaagccagactatatatacatggatgctatgggctttggaatgggaaattgt
tgtcttcaggtaacgttccaggcttgcagcatttctgaagcaagatatctctatgatcag
ctagccacgatctgccccattgtgatggcgttgagtgctgcatctccattctacagaggc
tacgtgtccgatattgactgtcgctggggagtaatctctgcatctgtagatgatcgaacg
cgagaagagagagggctggagccactgaagaacaaccattatagaatcagtaaatccaga
tatgattccatagacagttatctatctgaatgtggtgagaaatacaatgacattgatttg
acaatagacaaagatatctacgagcacctaataaaggaaggcattgatcaccttttggca
cagcatattgcacacttgttcattcgagacccattgactttgtttgaggagaaaatacat
ctagatgatgcaaatgaatccgaccattttgagaatattcagtctacaaactggcagaca
atgaggtttaagccacctcctccaaattcagatattggatggagagtggaattcagacct
atggaggtccagttaacagactttgaaaattctgcgtatgttgtgttcgtggtattgcta
accagagtgattctgtcatataaactagattttctcattcctttgtccaaggtggatgaa
aacatgaagatggcccagaaaagagatgctgtccggcagggaatgttttacttcagaaaa
gatatttgcaaaggtggaaacgctcttgtggatggatgtggctctgcacagaacgggacg
ggcaccgacacggaagagtacgccctgatgagcattgatacaattatcaatgggaaggaa
ggagtctttcctggtttgatcccaattttaaattcctatcttgaaagcatggaggtggat
gtggacacaaggtgcaccatcctaaactacctgaagctaataaaaaagagagcgtctgga
gaactaatgacagttgctcgatggatgagggaatttatcgcccagcatccagactacaag
caagatagtgtgataactgatgaaatgaattacagccttatttggagatgcaaccaaatc
gcacaaggccaggcagagtgtcctgaactgttgggggtaggatttaataagaaacaaagc
ggaaataaaactggctctttgtaa
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