Columba livia (rock pigeon): 102091318 Help Entry 102091318         CDS       T02912                                  Symbol SYNE2 Name (RefSeq) LOW QUALITY PROTEIN: nesprin-2   KO K19346   nesprin-2 Organism clv  Columba livia (rock pigeon) Pathway clv04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:clv00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     102091318 (SYNE2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:clv03036]     102091318 (SYNE2) Chromosome and associated proteins [BR:clv03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     102091318 (SYNE2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Spectrin_SYNE1 CH KASH Spectrin SYNE1 Motif Other DBs NCBI-GeneID:  102091318 NCBI-ProteinID:  XP_021148435 LinkDB All DBs Position Unknown AA seq 6994 aa AA seqDB search MASQQSSPSTEEQASSEIDDLHLSLQVQREFTQKKTFTSWINSILAKHTPPSVISDLYTD IQQGHLLLDLLEVLSGQHLPREKGCNTFQCRSNIENALTFLKSRSLKLINIHVADIIEGK PSIVLGLIWTIIFHFHIEELARTLACTYNQPSLDSSSAIDSSPKASRSAKKSAKIKERWK MSATKALLLWAKEQCSLHGSINVTDFKSSWRSGLPFLAIIQTLRPGLVDLEKAKCRSNKE NLKEAFRIAELELNIPRLLEPEDVDIVNPDEKSIMTYVAQFLQYSRNLHESEEDMQEKVS EAMSWLAAQEKKFAELLINTENETYYQKYKEMMSFMEAFNQEKKPFLPVLSSKRSEAELS EGRQQTREKWDKLVSQINEWKAKLDQMLPSPLDSIEAWLQEVEHLQAEDLPDLQDPFKAM LVFREKIVIFKGLMDCFDSHLDTLQSFKNEDEKNMPLVLPEKLEEMKRRFSNIPFTNSNT FLEYHCGLCTALANEVMLKLNIWDMKYGTKESVESLLESWNNFIEEKRLETLLETATHIC EDLKTENRSSPDFAGDPQEISKLLKTVESKISMCRDYISNVNTTLQKVLSSWSNYTENIH LLKTWLEEKRNEHPKEIPAEVVAKWNSVHGSLNEAGNYLIEVSKEQVGSNIAKELKKLNR RWAKFIKRTHFLGEESPDAAEKTRELLGNLEKIEELLGEVESWAAETGQLLGKISHEGTV EPETKEHLQSLAARGTSCQDQLVAAEELLQSPTQNVSSPVSQQHSGLQARVKEARGKIEA VMGDMNNILPKSEKRPAEQEALLNFEESQKELEASISKAVQLISQKLSPEECISRYEEAV NALDNKVLDKFLKAAEQLKNVSSDHEKLVVEEKSNDVRKRWEAVHHEIISCVQLVVEREK KKFNATFKKINKQLGKEKKLLSMDKTKGLLKEHEAFFSHEGSLRELRKSLEDLKILGRLS EEAVPGIETLTADCEQKLEKLQQIVADTYTALLSRAGKGHSSKKESSIVASENGEKPSSS QEIDILSVRETSRPAADVVLEPDVNHHNGESCAKKLEEDGDYSIPALLESYNTQRSNLEE LLQISRDKVASGFTDEIKGTSCLHNKLLELQVIEGEINSGWTQLENISSSLENLVDEVQQ AAISEMRSKLKGEWKELQDIISTRTNSLRTALEIVLPIENESILLCELDQQLKKKDIQQF NLMNSDLAYRELKELQRSILNQIEVCKQLEHLDSSARDEFNPIDLQAASKIMIYYQNQLE EMSHKMQIRETVLKDLEAFMASLRKLQSSIKCLTDSSGHPEIQGKTLRDAAQEISHMAEE AKCLDERLKTVDICLEDAECGRKTSCENLVLTLSEELNATYDPSSEQTLPEEEDLYKTFS TKNSELLRNIQDLRDRINKVGLKDPTIPAIQQRVKSLMELDKELDCAAVEMKPMREITNR LLHIKEEKAEEASEQCRVTERLWEDTKLLVAECQEQCARALELLKQYQSCKTSLTGIIQK QEIVLSQQTSYIGKENLNRLITKIEEAKEEFNDHSEDVDKINQICKNLQFQLNKMRSFEE PPFENEANIIVDRWLDINEKTENYCDNLGRAQALWDKLLSLSGTIDAWANEELKNAEGHC LTEEELTQLKACLRVQEQKLQKFDNTVAEIEELLNSNEPPLELQVIRSAVVQKMELIKEL LSTKRGTSELSVNTAELKGDLDLAKTQIGMTESLLKALSPSDTLEIFTKLEEIHQKILQQ EHHVTLLQEETDCPDVDELNKQLKCVTDLFNKKKHVFQDHFIGVLDRQCKNFNXXXXXXD CFDPSETKPILEERLQRLKHFLTSEGKDRDIQEVKTLLNKVKNYLPKASINHLTNRVRDQ EAELQRLISKCQKREKELGASLQQLSSLEESSTVLEEWLTAQEVKLEEIEKDETKLENFN KTLLMQRKPFDSMAQLANSLRETGLTDETISEASDLISRYQTLITHVSEMAGNTERLPVE GQNFEELAQDVSSWIKKLEEAVNNLNSQDSELSSDERINQIKEITALREAGGAKIQNMVA QGETLQRDEKNKPXXXXXXXXICRLAAERTSPEEQLQFNREQYEQSKEDLRLALTELEKQ QQEMGFALQPGLQEKQAQLTNYANLLQKAEDLTSRFNELESQEGHLKGCTGDPCFTEAEW LELKHQHDNLLSQLQTIVQTLESHVQEHLQFQDMVRGLSTELKTISEKLADSEGRAMEQP SAEQNQLKSQEQQGPLSQCEDMLKKILVLAETVKQNTSSPGQKFIKDEIETLESEHRSLE ERLENVKQKDENIFSEALELKDEFGNEIKKEDKADTMLKREIEITSDTPVAAEESPTAVE LKEPLEMHDVQDVNGNMSEKEKPNDTLLEESSALSDSPLQGVSQSKDRLEQTVQGEADKE SPGTDKHERVQEDVLDNAVQGGEAQVERHQDGVDIEGDETRTETHLAEEKPSDVKNQSYR EDVEQVQQSMCQKSQVPKSAASEKDGLESNPPVSAHEDTDAEVVVQKELFPGVQVNTEYF EEEQKVNELKNEVAELDIVLINEQLKELEKLQTELETWKAKSLCDSQEVFPDATGSNRAE LQSPEPVVPCWDRLLRELDALKAVKQQQYCLINEYQKNLSAAQSSMKNLSTEKDNIKMGP MNNTVLLGKIKACIESLRKERDVLNQLKTQQEGLSQHLTCMDKVLTESQMRRLEQWWQHM EQTVQKKHDQVVAEIDEFNLLMNKAQDIQRLIQEQYLQAELHSSAEGKAKCPVLWTTEVQ DIKHGLSLLKRRSELQMKRIWSDQEKAALENSIYDLQSKLEALSMQQTPQEDVQITSTAL MKHEMMKRLKENISWVKDSLSSLDQKAALFPSDVKSQIRSCQLMRDEVLNREPEIVSLDH GLQHIAPNLKPEEISDMTSLLQALQNSYKALVLKSAQRLQHLELQLEERQRLIAEIEKVH CQLRNAEMLARPDMNQTSTWSELINQHDLLKEILKDVQEIEGLISSHCKESQVTAGELSL SEQLFLIDQLRSLKNRAKKTQRQIQGKLREVEKKIGVYREFAEGVTSLQQDLNVLHFGEI NLEEDEILGAKQEVKDKCKALKEKILAFQSSLSQITKYKEIFECVGLDWDSREVDELQTK FFKIKNKIKEKIIRLDNVVRECDRIQTLLNKIQTATSTVRKEANIINDSSSSSPAENLIA AQILCQTVQQILCLTQEAANQINKNEVFDTPLKESKRQEIKTLEKDVEELNQFLKNLVSG LQGVNKEDIQSEVEHIFHIIKHIQLQLQQPLLLDLKMMQYQKMQWEAIQNMMQAKFSAIK CIMEKEMENQEEKSLTAGIETKLETLQDHEIQLKTDIAARVSALEEACKTGELYTEAVQR AAEFLEDYEAQVKSAPAKLSSSEEFCRMPQWKQEEFNSAKANIENLDSKLKNLVKPEDKI CLENTLTELVNKALALREKAQRKEADEQRYFEKYKSYLKTKDKVCDNLNKLEKMLRQSLS QIPMSYKEALEHLEESKILVSNIDSAEDDLVKLRQISGELMRLCKGRDRALGRTVTVLWE NWLGLLEAAKGLEINCDGIKKHFVSCFDMLFTXLERETIILDKLQEEQPESLKEKEKATR EELVELLDFVSSFEENINQQQLLLLLLLHRIRNILNTSENSEAEAALPALCEIKAMQDRC KKLYEKTQDHKDSVQAEIRERNKITEEINAVTNALQNAASVLLQDAGGKAGQLEEVQTVV DRESQTLKDIMEKLRIKYSEMYTIVPAEIEMQLEDCKKVLQGLEEKVSFEILQRSPQYVL KRKAETINSGLQAIEKMLQQKSENIAKAKEVQKQIWDMLDLWHYKLNELDAEVHDIVEQD SCHAQELMDILVTPHQQYQQVSQLAERRTAILNKAANKMEEYDELLKNVKVWIENTNCLL RADAQHDSAKSLRKHTGDLQMALEDSEQKQNLLHSFYLELEELTPVFETDHVMQQLNEID DQVATLQHEIAEILPQIQNVADELDAIESHVKVFEKDMAEMKTILSSEDLLEFSPKDQLK HGQVILDHVGPMQKTIVRIQSYEELLQLPGVKTQPFSVFQRARQLLRELKKLEKITKEQN DLLEEAVKKTEECEQEIEKLKQFLKNHLVEISHEDQPLAEKAHCPEGDMEAVKEEIIKLC QRKEDILTGMKNSMAELHQRLQQEVPESGDEPTASVLEYSDLIGTDVSGQQLKKRGIMSL LPSLDEESEDSSFRSKGSAATEQDVSFWPSERDDERHKEDSTASWSSGTLSDGIVQDVDE IMQSHIKRDEETPLQTLQSSEGPCTGDGSQATSDTPPPVPNATWGSRGKAEDAVDGSRPE PETILQVCQAQVAELEQWLDKTKVSLGSDHRTPKMQQMVELQLADYQVMLSEIEQKVLSL LEDCGHSADYQQQTEALSLKLNEVKCNLEKVQTMLQGTYHEEQIHNRERIDPEPFDILHS DGSSTSQAALAEQPHVWHNGFQHPQDMKAKTAEQKSLIDFIESCVEKMQPQFEDSMTQKL ELSDGESDPKSEQANPTSSPKDRTGNKWQFLQQELSSKMKSPLCQLVEPQITTKMNMLPR STFASAGTPTVEELKTYTVQLGDLSQEANVVHAQDNVAEEVSSNLDRKLFELLLAISRCL NNMEEMLNTSVLSTEEAAVQQALYETLSVELQKLHAYLSDKKDDLLKSISCAGGSTDVFC ECFNNLQARLEQTQAATASRSSSMKAGLDHNSNYQNETRLLYDQLTEKKAALQQYLNAIR GHNVSEQLQKTDACALELQNFENQVAKLRGHGERLQLPITLIQEAYKLEDVLDDMWGILK AKYMELNSPSISESQYEDLLHGFAELVAIGREKIAQDPKQLTKSRAALQSHLENHKDFFH NLMTHMAFMQTFSKKVAPSVFQKKEEFWKELVDEVKSLEEKACQYGIHLETLLKEWVEFD DECLAFNKELETLTSMLPSVNLVEETEERLMERIALLQQIKSSVDKKHARLYQMVKEGKK LLTAVSCPEIRSQVRKMEEQWLSLTKKVGHELHRLQTLLKLLVSYNRDSEELMKWLDSAQ QRMNFWKEQSLSVSQDLATVRDNINSLFTFSKEVDDKSSLKSSVVSTANQLFHLKQADTA ALRSSLAKFEQKWGELIIQLPAIQEKLHQLQMEKLSSREAIAELMTWLDHVEQQQGHEEP INAQCSAAQVRSLLQKYKEYMMEMNFKQSTVDFVNQSLLQMSTCDVKSKRYERTEFAECL GEMNLRWHRLQASLNRKIQDLENILEDITENENKAQTLHNWLEAQSDRLRSLQTPASLIS AQNTLDDCKELENQLTTKSKTLDELKQSLALNSGVEQTPEALSVRVAELCEMMDSIASQV SELKTSMQSVLEQWRVYDEVYAEVSVMTTRYLYSIDQCKPSVMSLEALKKQVKTLQSLQD ESENSEESWAKLQVAASNLKKNCSPSFAEIIEQKCTEAQTRWNSVNEDITDQLREAQATL QLWEPFDTLCTEAAAKLEQHKEQCAQLLDAHVPEDNVIEILEQRIQDIKNLQHGLQNIAG CHAQMSLLADQIKQQAGTAAQAVLLEKLQPLQRAHYLEKMLQGKLDELEFNLSQLEDFNK CLETLEGHVKNCTDTFDSLCLEGETDNSELLLNHTLELAALSPSIESLNEASIKLPLSDF TLKKMQSLTRQWSQKTAAALERCSILEGAQNDEKKFFQKCENWMKFLEKMKEALKTNIPG RFEELQEQQRVYEMLQTEISINQQTFNSIIAKVLLSLETGEAEKRTEFISKLTLLKEQWQ NVIRXXXQRKKNIHGLVSQWQLFRSSLRSISRFLADTNSFLAPVKSQDCYSLYQLRNLIH DFKSKAVIFQRWQTMYSLIIDVGEKLRTVSDPKTSAFLQEELSQLQQSWGDTQAQLEKKK MQLSSTVQSWDCCEKQTKELKSRLQELKEKVKDPLPVEHEELYKAKEHIKELEQSLADWA HNMKELRAMKVELAHCILSEDVMVLKEQVEHLHRQWEELCLRVSLRKQEIEDRLNAWIVF NEKNKELCSWLVQMESKVLQTADVSIEDMIDKLQKDCMEEINLFSENKLHLKQMGDQLIK ASNKSRVAEIDDKLNKINDRWQHLFDVIGARVKKLKETFGFIQVLDKNMSNLRTWLARIE SELSKPVVYDICDDQEIQKRLAEQQDLQRDIEQHTAGVESVFNICEVLLHDSDACANETE CDSIQQTTRSLDRRWRNICAMSMERRMKIEETWRLWQRFLDDYSRFEDWLKSSELLAARP NSSEVLYTHAKEELKKFEAFQRQIHERLTQLELINKQYRRLARENRTDSASKLKQMVHEG NQRWDNLQKRVAAILRRLKHFTNRRDEFEGMRESILVWLTEMDLQLTNVEHFSKSNFDDK MRQLNGFQQEITLNTNKIDQLIVFGEQLIQKSEPLDATLIEDELEELHRYCQEVFGRVAR FHQRLTSRHPGLDDEKDTSENEADPEDSREIQNDPWHKKAISEGPSSSQSLCHLMPPTQG HERSGCETPVSVDSIPLEWDHTGDVGGSSSHEDEEEATYYSALSDVEITENPEAYLKMTT KTLKASSGKSVSEAHPWHSPGSPVCRNHRYNQAEMVGNVLSGPETSTPYKPDYVKQLSSA SSSSIKDKNPSANMSDEEPQDDQELVNIAAAEKPSGITDRWELIQAQDLRDTLLMKQKQQ QWQQLNSDLNDISAWLDKTEQELDELQVKHPTSMQALEQRVKKLKDMLKALDNYKAVVLS VNRSSKEFQKADSMEFRELQNRLRKVNLHWEQVTRMLDHWRKDLREALLHCQEFHDESQK LILWLANADSRRNEAQITDPNADLDTVLACQKELMQLEKELLEQQLKVNSLQELTAYLLL KSDSDYTTADVVGSELKQLNEQVSRDLKKIQGNLGSRAFLMVPDVLDSGVYNPGAVKSSP AVKAITRRRSADGRNGSSTRCDCHPQPIQTTPQSPCFFYRVLRAALLFQLFFLLLLFLAS MIPLSEEDYSCTQANNFARSFHPMLRYTKGPPPT NT seq 20985 nt NT seq  +upstreamnt  +downstreamnt atggcatcacaacagtcatctccttcaacggaggagcaggcttcctccgaaatagatgac ctccatctatcactgcaagtgcagcgagagtttacacagaagaaaaccttcactagctgg ataaattcaatattggcaaagcatacacctccttctgttatctcggacctatatacggac atacagcaaggacatttgcttttggatctgttggaagtgctttcgggtcaacatctgcca cgggaaaaaggctgtaataccttccagtgcagaagcaacatagaaaatgctttgacattt ttaaagagcagatcactcaagctcataaatattcatgttgctgacattattgaaggaaaa ccttccattgtgcttggcttgatttggacaattatatttcatttccatattgaagaactt gccaggacacttgcttgtacctacaatcagccttcacttgattcttcaagtgctattgat tcctctccaaaggcgagccgatcagctaaaaaaagtgctaaaattaaggaacggtggaag atgtcagctacaaaggctcttttgctgtgggcaaaagaacagtgttcactgcacggctct atcaatgtgactgacttcaagtcaagctggcgaagcggtctgccttttttagccatcatc caaaccttacgaccaggtctagttgatttggagaaggcaaaatgtagaagcaataaagaa aacctgaaagaggctttccgaattgcagaactggagctgaatattccacggcttcttgaa cctgaagatgttgacattgtgaacccagatgaaaaatcgatcatgacttatgtggctcag tttttacaatactccaggaatttgcacgagtctgaagaagacatgcaggaaaaagtaagc gaggccatgagctggttggctgcacaggagaagaagtttgcagagttgctgatcaacacg gagaatgaaacatattaccagaagtacaaagaaatgatgtcatttatggaagcatttaac caagaaaaaaaaccctttctgcctgtgttgtcatcaaaaagaagtgaagctgagctgagc gaaggccggcagcagacaagagagaagtgggataaactggtctctcagattaatgaatgg aaagcaaagctggaccagatgttgccctcccctctggatagcattgaggcttggcttcag gaggtagaacatctgcaggcagaagatttgcctgatttgcaggacccgtttaaagcaatg cttgtcttccgagaaaaaattgtaatatttaagggtttgatggattgttttgattctcac ttggacaccctccaatcatttaagaatgaagatgagaagaatatgccactagtcttgcct gaaaagttagaggaaatgaaaagaagattcagcaatatccctttcacaaactccaacacc ttccttgaataccactgtggactctgcacagctcttgccaatgaggtgatgttaaagcta aatatctgggacatgaagtacgggacaaaagagtctgtggaatcactgctggaaagttgg aataatttcattgaagaaaagagacttgaaactctactggaaacggctactcacatctgt gaagacttgaaaaccgaaaacagaagcagtcctgacttcgctggagatcctcaagaaatt agcaaacttcttaagacagtggaatcaaagatttctatgtgcagagactatatttccaat gtaaataccaccctacagaaagtcctgtcttcctggagtaattatacagaaaatatccac ttactaaagacctggctggaagaaaaacgtaatgagcatccgaaagagatccctgctgag gtcgtggcaaagtggaattcagttcatggttccttaaatgaagctggaaactatctcatc gaagtcagcaaagagcaagttggatcaaatattgccaaagaactgaagaaactgaatagg aggtgggctaagttcatcaagaggacacactttcttggtgaagagagcccagatgctgct gaaaagaccagggagcttctggggaacttggagaaaattgaagagctccttggagaggtg gagagctgggcagcagagactggacaactgcttggcaagatcagtcatgaggggactgtg gaacctgagacaaaggaacatttgcagagcttggctgcaagggggacctcatgccaagat cagcttgtggcagcagaagagttattgcaatccccgacgcaaaatgtttcaagtccggtg tcccaacagcattctgggctgcaggcacgagttaaagaagccagaggcaaaatagaggct gtcatgggtgacatgaacaacatcttgcccaaatctgagaagagacctgcagagcaggag gctttgctcaattttgaagaatcccagaaagaacttgaggcctctatttcaaaggctgtg caacttatcagtcaaaaattaagtcctgaagaatgtatttcaagatatgaggaagctgtt aatgctctggacaataaagttctcgacaaatttttgaaagcagctgaacaactgaaaaat gtttcatctgatcatgaaaagctggtagtggaagaaaagagcaatgatgttcgtaaaaga tgggaggcagttcatcatgaaattatatcctgtgtccagctcgtagtagaaagagaaaaa aagaaatttaatgcaactttcaaaaaaatcaataagcagttaggcaaagagaagaaactc ctaagtatggataaaaccaaagggctcctcaaggaacatgaggcctttttttcacatgaa ggcagcctgagggaacttaggaagtcattagaagaccttaaaatattgggaagactatca gaagaagctgtgccaggcatagagacactgactgcagactgtgaacaaaagctagaaaag cttcaacaaattgtggcagatacttacacagccctgctgtctcgcgctggaaaaggacac tcgtctaagaaagagagctccattgttgcttctgagaatggagaaaagcccagttcttct caagaaattgatattctttcggtacgggagacctcaagacctgctgcagacgtagttttg gaaccagatgtgaaccatcacaatggagaaagctgtgcaaagaaattggaggaagatggt gattattccataccagcgttattagagagctataacacacaaagaagcaacctggaggaa cttttgcaaatcagcagagataaagtagcatctggctttactgatgaaataaaaggcact tcatgccttcacaataagctgcttgaactacaggtgatagagggtgaaatcaattctggt tggacacaattggaaaacatctcgtcttccttagaaaatcttgtggatgaagtgcagcag gctgctatctctgagatgagaagcaaactaaaaggagaatggaaagagcttcaggatatt ataagtaccagaacaaactctttaaggactgctttggaaattgttttgccaatagaaaat gagtccattcttctatgtgaattagatcagcagctgaagaaaaaggacatccagcagttt aatctgatgaatagcgatcttgcttatagggaactaaaggagctacaaagatccatatta aatcagattgaagtgtgcaaacaattggaacacctagatagttcagcaagagatgaattt aatccaatagatctgcaagctgcaagtaaaattatgatttactatcaaaaccagcttgaa gaaatgagccataaaatgcagatccgtgagacagtgcttaaagatctggaagcttttatg gcctcactgaggaagcttcagtcttccatcaaatgtctcacagattcctcaggtcaccct gaaatacagggaaaaacattgagagatgctgcacaagaaatttctcatatggcagaagag gctaaatgtttggatgaacgcttgaaaacagttgatatctgtttggaagatgctgaatgt gggagaaagacttcctgtgaaaaccttgttctgactttatctgaagaactaaatgcaact tatgatccctcaagtgaacagacacttccagaggaagaagacttgtacaagactttttcc acaaaaaacagtgaactccttagaaacattcaggatctacgtgacagaattaacaaagta ggcttgaaggatccaacaattccagctattcaacaaagggtaaaatcgttaatggaattg gacaaggaattggactgtgctgctgttgaaatgaaacctatgagagaaattactaatagg ctcctacatatcaaagaggaaaaagcagaggaagcaagtgaacagtgcagagttacagag aggttatgggaggatacaaaactcttggttgctgaatgccaggagcagtgtgcgagagct ctggagctcttgaagcaatatcaaagctgcaaaacgagtctgaccggcatcatccagaaa caggagattgtgctttcgcagcaaacttcttatattgggaaggagaatttgaacagacta ataacaaagatcgaagaggcaaaagaggaatttaatgatcactctgaagatgtagacaaa ataaatcagatctgcaaaaacctgcaattccagctcaataaaatgagaagctttgaggag cccccgtttgagaatgaggctaacattattgtggacagatggctggatatcaatgagaag actgaaaactactgtgataatttgggaagagctcaggctttgtgggacaaacttcttagt ttatctggcacaatcgatgcttgggcaaatgaagaacttaagaacgcagaaggccattgt ctgactgaagaggagcttacgcagttgaaggcctgcctacgagtgcaagagcagaaactc cagaaatttgacaacacggtggctgagatagaagaacttctgaacagtaatgaacctcca ctggagctacaggtcatcagatcagctgttgtgcaaaaaatggagctaataaaagagctc ttgtcaacaaagcgggggaccagtgaactcagtgtgaatacagcagaactaaaaggagat cttgatctggccaagacacagattggaatgactgaatcacttttaaaagctttgtctcct tctgacaccttagagatctttactaaattagaggagatacaccagaaaattctgcaacaa gaacaccacgtgacgttactccaagaagagacggattgtcctgatgtggatgaattaaat aagcagcttaagtgtgtcactgatttatttaataagaagaaacatgtatttcaagatcac tttatcggtgttttggaccgtcagtgcaagaattttaatngnnnnnnnnnnnnnnaggac tgctttgacccctcagaaacaaaaccgatactggaagaaagactgcagaggctaaagcac ttcctaacatctgaaggcaaagacagagatatccaagaggttaaaacgttgttgaataaa gtgaagaattacttgcccaaagcaagcattaaccaccttaccaaccgtgtgagagatcaa gaggcagaactgcagagattgatctccaaatgtcagaaacgggaaaaggaacttggtgct tctctccagcagctcagcagtcttgaagaaagcagcacagtcttggaagagtggctgact gctcaggaagtaaaactagaagagatcgaaaaagatgagacaaaacttgaaaacttcaat aaaacactattaatgcagagaaaaccatttgactccatggctcagctggcaaattccttg agggagactgggctgacagatgaaactatttcagaagccagtgaccttattagtagatac cagacactgataacacatgtaagcgaaatggcagggaatactgagagacttccagtggaa ggacaaaattttgaagaacttgcccaggatgtttcttcctggatcaaaaagctggaggag gctgttaataacctgaattcgcaggacagcgagttgtcatcagacgaaaggatcaatcag ataaaggaaatcacagctctcagagaagcaggaggggccaaaatacagaatatggtagct caaggagaaactttacagagagatgagaaaaataagccannnnnnnnnnnnnnnnnnnnn nncatctgtcggctcgcggctgaacgtacaagccctgaagagcaacttcagttcaacagg gagcaatatgagcaaagcaaagaagatctgagactggctctaactgaactggagaaacag caacaggagatgggttttgcccttcagcctggtttgcaggagaaacaagctcagctgaca aactacgccaacctcctgcagaaagcagaagacttaacttccagatttaatgaattggaa agccaggagggtcacctaaagggttgcactggggatccctgcttcacagaggcggaatgg ttggaattaaagcaccaacatgataatctcctcagccagctacagaccatagtgcagaca ctggaaagtcacgttcaagagcacctgcagtttcaggatatggtaagaggcctgagcact gagctgaaaactatctctgagaagcttgctgatagtgaaggtcgagcaatggaacaacca tctgctgagcaaaaccagttgaaatcacaggaacaacaaggacctcttagtcaatgcgaa gacatgttaaagaagattttggttttagcagaaactgtcaaacaaaacacctcttcacca ggccagaagtttattaaggatgagattgaaacacttgaaagtgaacacaggagtctggaa gaaagacttgaaaatgtcaagcaaaaggatgaaaatattttcagtgaagcccttgagttg aaagatgagtttggtaatgaaataaaaaaggaagataaggcagatacaatgctgaagaga gagatagagatcacttctgatactcctgttgctgcagaagagagccctacagcagtggag ttaaaggagcctttggaaatgcatgatgttcaagatgtaaatggaaatatgtcagagaaa gagaagccaaatgatacacttttggaggaaagcagtgcattgtcagacagcccattacag ggtgtcagtcaaagcaaggacagattggagcagactgttcagggtgaggctgataaagag agcccaggtacagacaaacatgagagggtccaagaggatgttctggacaatgcagttcag ggtggtgaagcacaagtggaaaggcatcaggatggtgttgatattgaaggtgatgaaaca agaacggaaacccatctggcagaggagaaacctagtgatgtgaagaatcagtcatataga 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tgtctggaaaatactctaactgaactagtcaataaggctttggcattaagggagaaggct caaaggaaggaagctgatgaacagaggtactttgaaaaatacaaaagctatctgaaaacc aaagacaaggtgtgtgataatcttaacaaactggaaaagatgcttagacagtctttgtct caaataccaatgtcttataaagaagctttggagcacttagaagaaagtaagattttagtc tccaacattgactcagctgaagatgatcttgtcaagctgaggcagatctctggagagctg atgagattgtgcaagggacgtgacagggcactgggcaggactgtaacagtgctgtgggaa aattggctgggtttgcttgaggcagcgaaagggctggaaattaactgtgatggaataaaa aagcactttgtctcatgctttgacatgctgtttacttagctggaacgagaaacaataatt ctcgataagctccaggaagaacagccagaaagtcttaaagagaaagagaaggccaccaga gaggaactggtagaattactagattttgtgagctcatttgaggaaaacatcaaccagcaa cagctcctgttactcctacttcttcaccgaataagaaacatcctgaatacatctgaaaac agtgaggcagaagctgcccttcccgccttatgtgagataaaggcaatgcaggatcgctgt aaaaagttgtatgaaaagactcaagaccataaggattctgtacaagctgagattcgagag aggaacaagatcactgaagaaataaatgctgtgacaaatgcattacagaatgctgcatct gtgttgttacaagatgctggtggcaaggcaggacaacttgaggaggttcagactgtggtt gatagagaaagtcaaactctaaaggatatcatggagaaactgcggatcaagtattctgaa 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tcagagctaaagacctcaatgcagtcagtactggagcagtggagagtatatgatgaagtt tatgcagaagtcagcgtgatgacgacaagatatttgtacagcatagaccagtgcaaacct tctgtgatgtcattggaagctttgaaaaaacaggtcaaaactctccagtctcttcaagat gaatcggagaacagtgaagaaagttgggcgaagctccaggttgctgccagtaacctgaag aagaactgctccccctcctttgcagagattattgaacagaagtgcacagaggcacagact aggtggaactcggtaaatgaagacatcacagatcaactgcgggaagcacaggcaacccta cagctttgggagccctttgatactttatgcactgaggcagcagccaagttagaacagcac aaagagcagtgcgctcagctcttggatgctcacgtgcctgaggataacgtgatagaaatc ctggagcagaggatacaggatataaagaatttacagcatggccttcaaaacatagcagga tgccatgcccagatgtctttgctggctgatcagataaaacagcaggctgggacagctgct caagccgtactcttggagaagctgcagccactccagagagcacactatttggaaaagatg ctgcaggggaagttagatgaacttgagttcaatctttcacaactggaggatttcaataag tgcctggaaacgctggagggtcatgtcaagaattgcacagacaccttcgatagtctctgt ctagagggagaaacagacaactcggaattgctcttgaatcacacactggagcttgctgca ctttctcccagcatagagagtttgaatgaagcaagcattaaactgccactcagcgacttc accctgaagaaaatgcagagcctgactcggcaatggagtcagaaaacagcagctgctctg gaacgctgcagtatacttgagggagctcaaaatgatgaaaagaaattctttcagaaatgt gaaaactggatgaaattcttagaaaaaatgaaggaagccttaaaaacaaatattccagga cggtttgaagaactgcaggagcaacagagagtatatgagatgctgcaaactgaaatttcc ataaatcagcagacatttaattctatcatagcaaaagttctactctccttggaaaccgga gaagcagagaaaagaacagagtttatttccaagctcacattgctgaaggagcagtggcag aatgttatccgnnnnnnnnagcagaggaagaaaaatatccatggactggtgagtcaatgg cagctcttcaggagttccctgcggagtattagcagatttcttgctgatacaaacagcttc ctcgcacctgtgaagagccaggactgctacagcctttaccagcttagaaatctaattcat gatttcaagagtaaggcagtgatttttcagaggtggcaaaccatgtactccttaatcatt gatgtcggggagaagttacgcactgtctccgatcccaagaccagcgcttttctccaggag gagctcagccagttacagcagagctggggggacacccaggcccagctggagaagaagaag atgcagctcagcagcactgtccagagttgggactgctgtgaaaagcaaaccaaggaatta aaaagcagactgcaagagctgaaggagaaagtaaaagatccacttccagttgaacatgaa gagctctacaaagccaaggagcacattaaggagctggagcagtcgctggcggactgggcc cacaacatgaaggagctgcgggccatgaaggtggagctggctcactgcatcctcagcgag gacgtgatggtgctcaaggagcaagttgaacatttgcacaggcagtgggaagagctctgc ttgcgggtgtctctgcggaagcaggagatcgaggacaggctcaatgcctggattgtgttc aatgaaaagaataaggagctgtgctcctggctggtacaaatggaaagcaaagtgttacag actgcagatgttagcattgaagacatgatagacaaattgcagaaggattgcatggaagaa ataaacctgttcagtgaaaataagcttcacttgaaacaaatgggcgatcagctaatcaag gctagcaacaagagcagagttgcagaaatagatgataagctcaacaaaatcaatgatcgc tggcagcatctctttgatgtcattggagcacgggtgaagaagctgaaggaaacatttggt tttatacaagtattggacaaaaatatgagtaaccttcgcacctggttggcccggattgag tctgagctttccaagcctgttgtttatgacatctgtgatgaccaagaaatccagaagaga ctggcagaacagcaggatctgcaacgagacatagagcaacacactgcaggggtggaatcg gtgtttaatatttgtgaagtcctgctacacgattcggatgcgtgtgctaatgagacagag tgtgactccatccagcagacgaccaggagtttggacagacggtggagaaacatttgcgcc atgtctatggaaaggcgaatgaaaatcgaggaaacctggcgcttatggcagaggtttttg gatgactattctcgttttgaagattggctgaaatcatctgaattgttggcagctaggcct aattcttcagaggttttgtacacccatgcaaaggaagagctgaagaaatttgaggcattc caacggcaaattcatgaacgcctcacccagctggagctgatcaataagcagtacaggcgc cttgcccgtgagaaccgcacggactctgccagcaagttgaagcagatggtccatgaaggc 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gatgaccaagaacttgtgaatatagcagctgcagaaaagccatcaggcattacggatagg tgggagctcatccaagctcaagacctcagagatacacttttgatgaaacagaaacagcag cagtggcagcagctgaactcagatctcaacgacatctctgcttggcttgataaaactgaa caagagctggatgagctccaagtgaagcatccgaccagcatgcaggcattggaacaaagg gtcaagaaactgaaagacatgcttaaagcacttgataactataaggcagtggtgctttct gttaaccggagcagcaaagaattccagaaagcagatagcatggagttcagagaacttcag aacaggcttcggaaagtgaacttgcactgggagcaagtgactcgcatgctggaccactgg aggaaagatttacgagaagccctgctgcattgccaggaattccatgatgagagccaaaaa ctaatcctgtggttagcgaatgctgacagccgaaggaacgaagcacagatcacagatcca aatgctgacctcgatacagtactggcatgccagaaggagctcatgcaactggagaaagag ctgctggaacaacagcttaaagtaaactcacttcaagaactcactgcttacctgctgctt aaatcagatagtgattacacaactgcagatgtagttggaagtgaactgaaacagcttaat gaacaagtttcacgtgacttaaaaaaaatacaaggaaatctgggttccagagcattcctg atggttccagatgtcttggactcaggcgtctataatccaggcgcagtgaaatccagccct gctgtgaaggcgatcaccagaaggagatcggcagatggcagaaacggcagcagcacaaga tgtgactgccatccacaacctattcaaacaactcctcagtctccctgcttcttttaccgt gtattacgagcagctttactttttcagttgttcttcctactgcttttatttctggcttcc atgattccgttatctgaggaagactacagctgcacccaggcaaacaactttgcccgttct ttccaccccatgctgcgatacaccaaggggcctccaccaacttag

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