Columba livia (rock pigeon): 102095154 Help Entry 102095154         CDS       T02912                                  Symbol UBR4 Name (RefSeq) E3 ubiquitin-protein ligase UBR4   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism clv  Columba livia (rock pigeon) Brite KEGG Orthology (KO) [BR:clv00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:clv04121]     102095154 (UBR4) Enzymes [BR:clv01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      102095154 (UBR4) Ubiquitin system [BR:clv04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     102095154 (UBR4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  E3_UBR4_N E3_UbLigase_R4 UBR4 zf-UBR ARM_LRRK2 Motif Other DBs NCBI-GeneID:  102095154 NCBI-ProteinID:  XP_021150943 LinkDB All DBs Position Unknown AA seq 5021 aa AA seqDB search MNESEILHHDKQYEPFYSSFVALSTHYITTVCGLIPRNQLQSVAAACKVLIEFSLLRLEN PDEACAVSQKHLILLIKGLCTGCSRLDRTEIITFTAMMKSAKLPQTVKTLSDVEDQKELA SPVSPELRQKEVQMNFLNQLTSVFNPRVSSSASVTPETQVEGESEDQASTDQTSAAKTKS IFIAQNVASLQELGGSEKLLRVCLNLPYFLRYINRFQDAVSANSFFIMPATVADATAVRN GFHSLVIDVTMALDTLSLPVLEPLTPTRLQDVTVLALSCLYAGVSVATCMAILHVGSTQQ VRTGSTSSKEEDYENDAATIVQKCLEIYEMIGQAISNSRRAGGEHYQNFQLLGAWCLLNS LFLILNLSPTALADKGKEKDPLAALRVRDIIARTKEGVGSPKLGPGKGHQGFGVLSVVLA NHAIKLLSSLFQDLQVEALHKGWESDGPPAVLDVMAQSTSIQRIQRLIDSVPLTNLLLTL LSTSYRKACVLQRQRKGSMSSDASASTDSNTYYEDDFSSTEEDSSQDDDSEPILGQWFEE TISPSKEKVAPPPPPPPPPLESSPRVKSPNKQSAGENGNILASRKDPELFLSLASNILNF ITSSMLNSRNNFIRNYLSVSLSEQHMATLASIIKEVDKDGLKGTSDEEFAAALYHFNHSL VTSDLQSPALQNTLLQQLGVAPFSEGPWPLYIHPQSLSVLSRLLLIWQHKATTQGDPDVP ECLKVWERFVGTLKQNALQGTLPSDTEDLNVEHLQLLLLIFHNFSERGRRSIMMLCIQTI VELTANMDTQQCSVPLIVARLLLVFDYLLHQYSKAPMYLFEQVQYNLLTPPLGWVSGSQD SSRRMSVPLYHGFKEVEENWTKHCSSDTAPQPRFYCILSLEASEDDLNRLDSAVCEVLFS RTMKYDELYTALTSLLAAGSQFDTLRRKENKNVTALEACALQYYFLILWRILGILPPSKN YMNQLATNTPEMSECDILHTLRWSSRLRIASYVTWIKDHLTKQGMKADHAASLIELASSK CSSVKYDVEIAEEYFARQISSFCGVDCTTILQLHEVPSLQSIYTLDAAISKIQVSLDEHF SKLAAETDPHKSSEITKNLLPATLQLIDTYATFTRSYLLRSLSEEGSAENKPSEEKLRGY AAVLAIGSSRCKSNTLGPALVQNLPSAVQTLCESWNNIHTNEFPNIGSWRNAFANDTIPA ESYISAVQAAHLGTLCSQSLPLAASLKHTLLSLVRLTGDLIVWSDDLNPPQVIHSLLPLL LESSTESVAEISSNSLERILGPAESDEFLARVYEKLITGCYNILAHHSDPNSGLDESILE ECLQHLEKQLESSQARKAMEEFFSESGELVQIMMATANENLSAKFCNRVLKFFTKLFQLT EKSPNPSLLRLCSSLAQLACVEPVRLQAWLTRMTMSPPKDSDQLDIVQENRQLLQLLTTY IVRENSQVGEGVCTVLLSTLIPMATEMLANGDGTGFPELMVVMATLASAGQGAGHLQLHG AAVDWLGRCKKYLSQKNVVEKMNANVMQGKHVTILECTCHIVSYLADVTNALSQTGGQGP SHLSVDGEERAIEVDSDWVEELAVEEEDSQAEDSDEDSLCNKLCTFTITQKEFMNQHWYH CHTCKMVDGVGVCTVCAKVCHKDHEISYAKYGSFFCDCGAKEDGSCLALVKRTPSSGMSS TMKESAFQSEPRVPESVIRHASTSPAEKAKVTISEGKGPDEEKPKKSSLCRNVEGCREEL QSQANFSFAPLVLEMLNFLMDAIQINFQQASAMGSSSRAQQALHELHTLDKSVEMTDQLM VPTLGSQEGAFENVRMNYSGDQGQTIRQLISAHVLRRVAMCVLSSPHGRRQHLAVSHEKG KITVLQLSALLKQADSSKRKLTLTRLASAPVPFTVLSLTGNPCKEDYLAVCGLKDCHVLT FSSSGSVSDHLVLHPQLATGNFIIKAVWLPGSQTELAIVTADFVKIYDLSVDALSPTFYF LLPSSKIRDVTFLFNEEGKNIIVIMSSAGYIYTQLMEEASSAQHGPFYVTNVLEVNHEDL KDSNGQVAGGGVSVYYSHVLQMLFFSYCQGKSFAATISRANLEVLRLFPINIKSSNGGSK TSPALCQWSEVMNHPGLVCCVQQTTGVPLVVMVKPDTFLIQEIKTLPAKAKIQDMVAIRH TACNEQQRTTMILLCEDGSLRIYMANVENTSYWLQPSLQPSSVISIMKPVRKRKAAAITT RTSSQVNFPIDFFEHNQQLTDVEFGGNDLLQVYNIQQIKHRLNSTGMYVANTKPGGFTIE VTNNNSTMVMTGMRIQIGTQAIERAPSYLEIFGRTMQLNMTRARWFDFPFTREEALQADK KLTIFVGASVDPAGVTMVDSIKIYGKTKEQFGWPDEPPEDFPSASVSNVCPPNLNQGNGT GDTESAVPAAASGTVLERLVVSSLEALESCFAVGPVNEKEKNKMAAQELATMLLSMPAPA SVQQQTKSLLASLHTSRSAYHNHKDQALLSKAIQYLSSSTKEGKDLDPEVFQRLVITARS IAIMRPNNLVHYTESKLLQLETENEEGQEAQKHAEGDGCTFITQLVNHFWKLHASKPKNA FLAPACLPGLTHVEATVNALVDIIHGYCTCELDCIHTASKIYMQMLLCPDPAVSFSCKQA LIRVLRPRNKRRHVTLPSSPRSNTPMGDKDDDDDDDAEDKLQSSGIANGEHIRQESQEQS EVDHGDFEMVSESMVLETSENVNNGNPSPLEALLAGAEGFPPMLDIPPDADDETMVELAI ALSLQQDQQGSSSSALGLQSLGLSGQAPSSSSLDAGTLSDTTASAPASDDEGSTAATDGS TLRTSPADHGGSVGSESGGSAVDSVAGEHSVSDFCSQVILMLTTDLDGDDEKDKGALDNL LSQLIAELCMDKKDVSKKNERSPVNEVHLVVMRLLSVFMSRTKSGSKSSICESSSLISSA TAAALLSSGAVDYCLHVLKSLLEYWKSQQNDEEPVATSQLLKPHTTSSPPDMSPFFLRQY VKGHAADVFEAYTQLLTEMVLRLPYQIKKIADTNSRIPPPIFDHSWFYFLSEYLMIQQTP FVRRQVRKLLLFICGSKDKYRQLRDLHTLDSHVRGIKKLLEEQGIFLRASVVTASSGSAL QYDTLISLMEHLKACAEIATQRTVNWQKFCIKDDSVLYFLFQVSFLVDEGVSPVLLQLLS CALCGSKVLSVASSSGSSSASSTAAPAASGSGQPATQSKSSTKKSKKEEKEKEREGESSG SQEDQLCTALVNQLNKFADKETLIQFLRCFLLESNSSSVRWQAHCLALHIYSWPELPAYG RKAAQFVDLLGYFSLKTQQTEKKLKEYSQKAVEILRTQNHILTNHPNSNIYNTLSGLMEF DGYYLESDPCLVCNNPEVPFCYIKLSSIKVDTRYTTTQQVVKLIGRHTISKVTVKIGDLK RTKMVRTINLYYNNRTVQAIVELKNKPARWHKAKKVQLTPGQTEVKIDLPLPIVASNLMI EFADFYENYQASTETLQCPRCSASVPANPGVCGNCGENVYQCHKCRSINYDEKDPFLCNA CGFCKYARFDFMLYAKPCCAVDPIENEEDRKKAVTNINTLLDKADRVYHQLMGHRPQLEN LLCKVNEAAPEKPQDESGSSGGISSTSASVNRYILQLAQEYCGDCKNSFDELSKIIQKVF ASRKELLEYDLQQREAATKSSRTTAQPTFTASQYRALSVLGCGHTSSTKCYGCASAVTEH CITLLRALATNSAIRHILVSQGLIRELFDYNLRRGTAAMREEVRQLMCLLTRDNPEATQQ MNDLIIGKVSAALKGHRANPDLASSLQYEMLLLTDSISKEDSCWELRLRCALSLFLMAVN IKTPVVVENITLMCLRILQKLIKPPAPTSKKNKDVPMDALTTVKPYSNEIHAQAQLWLKR DPKASYEAWKKCLPARGIDANVKSLSKAELHQLYLAEKYVWKWKQFMSRRGKRTCPLDLK LGHNNWLRQVLFTPATQAARQASCTIVEALTTIPSRKQQVLDLLTSYLDELSIAGECAAE YLALYQKLIKPAHWKAYLAARGVLPYIGSLITKEIARLLALEEATLSTDLQQGYALKSLT GLLSSFVEVESIKRHFKSRLVGTVLNGYLCLRKLVVQRTKLIDETQDMLLEMLEDMTTGT ESETKAFMAVCIETAKRYSLDDYRTPVFIFERLCSIIYPEENEVTEFFVTLEKDPQQEDF LQGRMPGNPYSSNEPGIGPLMRDIKNKICQDCDLVALLEDDSGMELLVNNKIISLDLPVA EVYKKVWCPTNEGEPMRIIYRMRGLLGDATEEFIESLDSTTDEEEDEEEVYKMAGVMAQC GGLECMLNRLTGIKDFKQGRHLLTVLLKLFSYCVKVKINRQQLVKPEMNTLNVMLGTLNL ALVAEQESKDSGGAAVAEQVLSIMEIILDESNAEPLSEDKGNLLLTGDKDQLVMLLDQIN STFVRSNLSVLQGLLRIIPYLSFGEMEKMQILVDRFKPYCNFDKYDEEHSGDDKVFLDCF CKIAAGIKNNSNGHQLKDLILQKGITQNALDYMKKHIPSAKNLDADIWKKFLSRPALPFI LRLLRGLATQHPATQVLIGTDSITNLHKLEQVSSDEGIGTLAENLLEALREHPEVNKKID AARKETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQMEELIEEPGLTCCICR EGYKFQPTKVLGIYTFTKRVALEEFENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGRE EWESAALQNANTKCNGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNVHDIK LLFLRFAMEQSFSVDTGGGGRESNIHLIPYIIHTVLYVLNTTRATSREEKNLQSFMEHPK EKWVESAYEVDGPHYYTVLALHISPPEKWKAMRVEILKRLLVTSHARVVSPGGASRLADK AVKEYATYRSGLLFWALVDLIYNMFKKVPTSNTEGGWSYSLAEFIRHNDMPIHEAADKAL KTFQEEFMPVETFSEFLDVAGLLSEISDPDSFLKDLLNSIP NT seq 15066 nt NT seq  +upstreamnt  +downstreamnt atgaatgaatctgaaatcctacaccacgacaaacagtatgagcctttttactcttccttc gttgcactttctacacattacatcactaccgtgtgtgggctcataccaagaaaccagttg caatcagtggcggctgcttgtaaagtcctgattgaattctcgctgctgcggctggagaac ccagatgaagcgtgcgctgtttcgcagaaacacctcattctgctgataaaggggctgtgc acaggctgcagccgcctggatcgaactgaaattatcaccttcacggcaatgatgaaatcg gccaagctgcctcagactgtcaaaaccctctctgatgtagaggaccagaaggagctggcg tccccggtgagcccagaactaagacaaaaagaagtacagatgaacttcctcaaccagttg acatccgtcttcaaccccagagtctcctcgtcggcatctgtcacaccagagacacaggtg gaaggagagagcgaggatcaagcttccacagatcaaacctctgcggcaaagacaaaaagc atattcatcgctcagaatgtagccagcctgcaagaacttggtggctccgaaaaactgctg agagtctgcctgaacctcccctactttttgcgatacataaatcgattccaggacgccgtg tcagccaactcgttttttattatgccagccacagtggcagatgccaccgctgttcgcaat ggattccattcgctggtaatagacgtgaccatggcgctggatactctgtccctgcccgtg ctggagcccctgacacccacgcgtctccaggatgtgactgttcttgccctcagctgtctc tatgcaggtgtgagtgtggcaacctgcatggccatcctacacgtggggagcactcaacag gtacgaaccgggtcaacaagttccaaagaagaagattatgaaaatgatgctgctactatt gtacagaaatgtcttgaaatctatgaaatgattggacaagccatcagcaattcacgccgt gctgggggtgagcattatcagaacttccagctgcttggggcttggtgtttgctaaacagc ctcttcctcatcttgaacctcagccccacggccttggctgataagggaaaggagaaagat ccactggctgctcttcgcgtcagagacattattgcacgtactaaggagggcgttgggtct cccaaactaggaccaggcaaagggcatcaagggtttggtgttctctcagtggtcttagca aatcatgctatcaaattgctgtcatcactgtttcaagatctgcaagtggaggcattgcac aagggctgggagagcgatgggccgccagcagtgctggatgtcatggctcaaagcacatcc atccagagaattcagcgcctgatcgattctgtaccactcactaatctgctgctgactttg ctgtctacttcctacagaaaggcttgtgtcttgcagcgtcagaggaagggttccatgagc agtgacgcaagtgcctccactgattccaatacttactatgaggacgattttagcagcacc gaggaggacagcagccaagatgacgacagtgaaccgatccttgggcagtggtttgaggag acgatctctccgagcaaagagaaggtggccccgccgcccccgcctccaccaccgcctttg gaaagctcgccccgagtgaagagccccaacaaacagtcggccggagagaacgggaacatc ctggccagccgcaaagatcccgaattgtttttaagcctggcttcaaacattttgaacttc atcacttcttccatgctgaactccaggaataacttcattcgcaactacttgagcgtctct ctttcggagcagcacatggctacgctagctagcatcatcaaagaggtggataaggacggg ctcaagggcacgtcggatgaggagtttgctgctgcactgtatcacttcaaccattccttg gtgacctcagatcttcagtcccccgccttgcagaacacgcttctccagcagctgggagtc gccccattttctgaaggtccgtggcctctctacatccatcctcaaagtctgtcggtgctt tcgcgacttctcctgatttggcagcataaagccactacccagggagatcctgacgttcca gaatgccttaaagtttgggaaaggtttgtgggcacactgaagcaaaacgccttgcaggga actcttcccagtgacaccgaagacctgaatgttgaacatctccagctgctgctgcttatt tttcacaatttctctgagaggggccgcagatctatcatgatgctctgtatccagacaatt gtggagctgacggcgaacatggatacccagcagtgttctgtgccgcttatcgtggcacgt ctgctcttggtgtttgactacctgctccatcagtattccaaggcccccatgtacctattt gaacaggtgcaatataatttgctgaccccaccccttggctgggtgagtggatcccaggac agtagcagacgaatgtctgtcccactttatcatgggtttaaagaagtggaagaaaactgg accaaacactgttcatcagacacagctccacagcccagattctactgcatcctgtctcta gaagcttctgaggatgatctgaaccgtctcgatagcgcggtttgtgaggtcctgttctct aggactatgaagtatgatgagctttacacggccctgacttcactgcttgcggctgggtca cagttcgatacactcaggaggaaggagaacaaaaacgtcactgcgctggaagcctgtgca cttcagtactacttcttgatactctggcggatattagggattttgcctccatccaaaaac tacatgaatcaattggccacgaacacacccgagatgagtgaatgtgatattttacacacg ttgcgctggtcttcccgtctgcgaatcgcatcttatgtcacatggatcaaggatcacctt acgaagcaaggcatgaaagctgaccatgctgcttctctcattgaattggcctccagcaag tgcagctcggtgaagtacgatgtggaaatagcagaggaatactttgctcgacagatatct tctttctgtggtgttgattgcacaactattctccagctacacgaagttcctagtttacaa tccatttacaccctcgatgctgcaatttccaagatccaggtttctctggatgagcacttt tccaagctagctgcagaaacggatccacacaagtcttcagagataaccaaaaacctcctg cctgctacgctgcagcttattgacacttacgctacattcaccagatcttacttactacgg agcctctctgaagagggctctgctgaaaacaaaccctctgaagagaagctacgaggttat gctgctgtcctggccattggatccagccgttgcaagtctaatactctaggtccggcgctt gttcagaacttgccatcagctgtgcaaactttatgtgaatcgtggaacaacattcacaca aatgagtttccaaacattggctcgtggcgcaacgcctttgcgaatgacacaatccctgca gaaagctacatcagcgcggttcaggccgcccacctgggtaccctgtgcagccagagttta ccccttgcagcttccctcaagcacaccctgctctccctggtcagactcactggggatctc attgtctggtcagatgatttgaacccgccacaggtgattcattccctattgcccctcctt ttggagagcagcacagagagtgtggcagagataagcagcaactccctcgagaggatcttg ggccctgcggaatcagatgaattcctggcgcgtgtttacgagaagctgatcacaggatgc tataacatactggcccatcactctgatccaaacagtggcctggatgagtccatcttggag gagtgtttgcaacatctggagaagcagctggagagcagccaggcccgcaaagccatggag gaattcttctcagaaagtggagaactggtccagatcatgatggcgacagccaacgaaaac ctctcagcaaagttctgtaacagggtgctgaaattcttcaccaagctcttccagctgact gagaagagtcccaaccccagcctgctgcgcctctgcagctctttggctcagctggcctgc gtggagcctgtccggctgcaggcctggctaaccaggatgaccatgtccccacccaaagat tcagatcagctggacatcgtgcaagagaacaggcaactgctgcaactcttgacaacttac atcgttcgggaaaatagccaagtcggagaaggcgtgtgcactgttctgctgagcaccctg atcccgatggccacggaaatgttggccaatggtgacggcacgggctttcctgagctgatg gtcgtgatggcgactttggccagtgcaggacagggtgcgggacacctccagcttcatggt gctgctgtcgattggcttggcagatgcaagaagtacctgtctcaaaagaacgtggtagaa aaaatgaacgcaaatgtcatgcaagggaagcatgtgactatcctggagtgtacgtgccat attgtctcttacctggctgatgtcactaacgcgctgagccagaccggtggccaaggaccc agccacctttctgtggatggagaggaacgggccatcgaggtggattcagactgggtggaa gagctggcagtggaggaggaagactcgcaggctgaagactcggatgaagattccctttgt aataaactctgtaccttcaccatcacacagaaagaattcatgaatcaacactggtatcac tgtcacacttgcaagatggttgatggggttggtgtttgcacagtttgtgcgaaagtttgt cacaaggatcatgagatctcatatgccaaatacggatcgttcttctgcgactgtggagcc aaggaagacggcagttgcctggctttggtgaagagaactcccagcagtggtatgagctct accatgaaagaatccgccttccagagcgagccccgagtgcccgagagtgtcattcggcac gcgagcacctcccctgcggagaaagccaaggtcaccatcagcgaggggaagggccctgat gaagaaaaacccaagaagagcagcctgtgtagaaatgttgagggctgtcgagaggaattg cagtcccaggccaacttctcctttgcacctttggtgctggagatgctgaatttcctgatg gatgcgattcagatcaacttccagcaagcctcagccatggggagcagcagccgtgcgcag caagctctccatgagctgcacaccttggacaagtcagtggaaatgacggatcagttgatg gtcccaactcttggctctcaagaaggcgcttttgagaacgtccgtatgaactacagcggg gaccagggccagacgatccggcagctgatcagcgctcacgtgctgaggcgggtggcgatg tgtgtcctgtcgtccccgcatggccgccggcagcacctggctgtcagtcacgagaagggc aagattacagtccttcagctctcggcgttgctgaaacaggctgattccagcaaaagaaaa ctgaccctaactcgcctggcatctgcgcccgttccgttcacggtgctgagcctgaccggc aatccctgcaaggaggactacctggccgtgtgcggactgaaggactgccacgtcttgaca ttcagcagctctggatcagtctctgatcatttggtccttcatccccaattagccactggt aatttcatcattaaagctgtgtggctgccaggatcccaaacagagctcgctatagtgact gcagactttgtgaagatctacgatctctctgtagatgccttgagcccaactttctatttc cttctgccaagttccaaaatcagggatgtcactttccttttcaacgaggaggggaagaat ataattgtgatcatgtcctctgctggctacatctacacgcagctcatggaagaggcgagc agcgcccagcacggaccgttctacgtcaccaacgtgcttgaagtcaatcacgaggacttg aaggacagtaatggccaggtggcaggaggtggggtgtcagtgtattactcccatgtgctg cagatgttgttcttcagttactgtcaaggcaaatcctttgcagccaccatcagccgggcc aatctggaagtgctgcggctgttcccaattaacataaagagttcaaatggtggcagtaag acttcaccggcgctgtgccagtggtctgaggtgatgaaccaccctggcctggtgtgctgt gttcaacaaaccacgggtgtcccgctggtggtgatggtcaagccggacacctttctcatc caggagattaaaaccttgccagccaaagcaaagattcaggacatggtggccatccgtcac acagcctgcaatgagcagcagaggaccactatgatcctcctgtgtgaagatggcagcctg aggatctacatggccaatgtagagaatacgtcctattggctccagccttctcttcagccc agcagcgtcatcagcatcatgaagcccgttcgcaagcgcaaggcagctgctatcacaact cgcacatccagccaagtgaacttccctattgacttcttcgaacacaaccagcagctcaca gacgtagagtttggaggcaacgatctgctccaggtttacaacattcagcagataaagcac cgactcaattccactggcatgtatgtggccaacacgaagcctggtggtttcaccattgaa gtgaccaacaataacagcaccatggtgatgacaggcatgcggatccagattggcacacag gccatcgagagagcgccctcgtacctggagatctttggccgcaccatgcagctgaacatg accagggctcgttggtttgacttccctttcactcgcgaggaagctttgcaggctgacaaa aaactgaccatttttgttggggcttctgtggatcctgctggagtcaccatggtggattcc ataaaaatttatggcaaaaccaaagaacagtttgggtggcctgatgagcctcccgaggat ttcccatctgcttcagtgagcaacgtgtgtcccccaaacctgaaccaagggaacggcacc ggggacacggagtcggctgtgcctgccgcggccagcgggactgtcctggagaggctagta gtgagttctttagaagcgctggaaagctgctttgctgtaggaccagtcaacgagaaggag aaaaataagatggcagctcaggaactggctactatgctgctgtccatgccagctcctgcc agcgtccagcagcaaaccaagagcctcttggctagtttgcacaccagccgctcagcgtac cataatcacaaggatcaagcattgttaagtaaagccattcagtatttgagttcctcaacc aaagaaggaaaggaccttgatcctgaagtgtttcagaggttggtcatcactgctcgctcc attgctattatgagacccaacaatctggtccattatacggaatccaagctgctgcagttg gaaacagagaacgaagaagggcaggaggcccagaaacacgctgaaggagatggctgcacg tttattacccagctggtcaaccacttctggaagctacacgcatcaaaacccaaaaacgcc ttccttgcccctgcctgcttgccaggtctcactcacgttgaagccacagtcaatgcgttg gtggatattatccatggatactgcacgtgtgagctggattgtatccatacagcatccaag atctacatgcagatgttactttgcccggatcctgcagtgagcttttcttgcaaacaagcg ttgatcagagtgctgagaccaaggaacaagcggagacacgtcaccttgccgtcctcccct cggagcaacactcctatgggagataaggatgatgatgatgatgatgacgcagaagacaag ctgcagagttctgggatagcaaacggcgagcacatccgacaggaaagccaggagcaaagc gaagttgatcacggggacttcgagatggtgtctgaatctatggttctggagacttctgaa aatgtgaataatgggaacccttctcccctggaggctcttctggccggagcagagggtttc cctccgatgctggatattcccccagatgcagatgatgaaacaatggtggaactggctatt gccctgagcctgcagcaagatcagcaagggagcagcagtagtgcacttggacttcagagc ttagggctgtctggccaagcacccagctcatcttcccttgatgccggaacgctgtcggat acaacagcatcagctccagcgtctgatgatgaaggcagcacagctgcgacggacggctcg acccttcgcacttcgcccgcggaccacggtgggagcgtgggctccgagagcgggggcagc gccgtggactccgtagccggggagcacagcgtctctgacttctgttcccaggttattctg atgctcacaacagacctagatggagatgacgagaaagacaagggagctttggataacctt ctgtcccagctgattgcagagctgtgcatggacaaaaaggatgtgtccaagaaaaacgaa cgctctcctgtgaatgaagtgcacttggtggttatgaggctgctgagtgtgttcatgtcc cgaacgaagtcaggatccaagtcttccatttgtgagtcctcctccctcatctccagtgcc actgctgctgccttgttgagctctggtgctgtcgactactgtctgcacgtgttgaagtct ctgctggagtactggaaaagccagcagaacgacgaggagcctgtagccaccagccagctc ctgaaacctcacacgacttcttctccccctgacatgagcccttttttcctccgtcagtac gtgaagggtcacgctgcagatgtttttgaggcctacactcagctcctgacagagatggtt ctgcggctgccctatcagatcaagaagattgcggacacaaactcccgcatcccacctccc atctttgatcactcctggttctactttttgtctgaatacctgatgatccagcagactcca ttcgtgcgccgccaagtccgcaagcttttgctctttatctgtggatcaaaggataaatac cgccagctccgagaccttcacaccttggactctcacgttcgtggaatcaaaaagctcctg gaagagcaaggcattttccttcgtgccagcgttgtcacagcgagctcgggctctgccctg cagtatgataccttgatcagcttgatggaacacttaaaggcttgtgccgagatcgccacg cagcgaacagtaaactggcagaaattctgcattaaagatgactcggttctgtatttcctc ttccaagtcagcttcctggtagacgaaggagtgtcgccagttctcctgcagctgctttct tgtgctctgtgtggcagcaaagtgctgtctgtagcttcatcctccggatcatcaagcgcc tcttccaccgctgctcccgcggcttcgggctctgggcagccagcgacacagagcaaatcc tccactaaaaagagcaagaaagaagaaaaggaaaaggagcgagagggcgagagctcgggc agccaggaagatcagctgtgcacagctctggtgaaccagctcaacaagtttgctgacaag gagaccctcattcagttcctgcgctgcttcttgctggagtccaactcctcgtcggtgaga tggcaggcgcactgcctggcgctccacatctacagctggccagaacttccagcctatgga aggaaagctgcccagtttgtagatctcctgggatacttctctctgaaaacacagcagacc gagaaaaagttgaaggaatactcccaaaaggccgtggagatcctccggactcaaaaccac attcttaccaaccaccctaactccaacatttacaacacgctgtctgggctgatggaattt gatggctattacctggagagcgatccttgccttgtctgcaacaacccagaggtgcccttc tgctacatcaagctttcctccatcaaagtggacacacgttataccaccacccagcaagtg gtgaagctcatcggcaggcacaccatcagcaaagtgaccgtgaagatcggagacctgaaa cgcaccaaaatggtgcgaaccatcaacctctattacaacaacaggacggtgcaagccata gtggagctgaagaacaagccggctcgttggcacaaagctaaaaaagtccagctgacccca ggccagacggaggtgaagatcgatttgccgctgcccattgtggcttcgaacctcatgatc gaatttgcggatttctacgagaattaccaggcgtccacggagaccctgcagtgccctcgg tgcagcgcgtccgtccccgccaacccgggggtgtgcgggaactgcggcgaaaacgtgtac cagtgccacaagtgcagatccattaattacgacgagaaggatcccttcctttgcaatgcc tgcgggttctgtaaatacgctcgctttgacttcatgctgtacgccaagccttgctgcgcg gtggatcccatcgaaaatgaagaggatcgaaagaaggcagtaacaaacatcaacactctc ctggacaaggctgacagggtgtatcaccagctaatgggacaccgaccgcagctggaaaac cttctgtgtaaagtgaatgaggcagctcctgaaaagccccaggatgaatctggtagtagt ggagggataagttctacctcagctagtgtgaacagatacatactccagttagcccaggag tattgtggtgactgcaagaactctttcgatgaactttccaaaatcatccagaaagtgttt gcctctcgaaaggagctcctggaatacgatctccagcagagagaggcagcaacaaaatcc tctcgaaccactgcccagcccacgtttactgccagccagtatcgtgccttgtccgtttta ggctgcggccacacgtcgtcgacgaaatgctacggctgcgcctcggccgtcaccgaacac tgcataaccttgctccgcgctttggcgaccaactctgccatcaggcacatcctcgtgtcc cagggccttatccgagagctctttgactacaacttgcgccggggcacggccgcgatgcgg gaggaggtccgtcagctcatgtgccttctgaccagggacaatccggaggccacacagcaa atgaatgacttaataatcgggaaggtttctgcagctctgaagggacaccgggcaaatcca gacttggctagcagcctccagtatgaaatgttgctgctaacagattccatctcgaaggaa gacagctgctgggagctccggctgcgttgtgctctcagcctcttcctgatggcagtgaac attaagactccagtggttgtcgaaaacatcaccctcatgtgcctgcgcattcttcaaaag ctgatcaagccacctgctcctaccagcaagaaaaacaaggatgtgcctatggatgctctc accactgtgaagccttacagcaatgaaatccatgcacaagctcagctgtggctcaagagg gaccccaaagcatcgtacgaagcttggaagaagtgcctccctgccagaggtatagatgcc aatgtgaaatctctcagcaaagctgagcttcaccagctctacttggcagaaaagtacgtc tggaaatggaaacagttcatgagtcgccgtgggaagagaacttgccctctggatctcaag ctgggacacaataattggctgcgacaggtgctgtttactcctgctacccaagccgcaaga caagcctcgtgtacgatagtggaagctctgaccaccatccccagccgcaaacagcaggtc ctcgatctcctgacaagttacctggatgagctgagcattgctggcgagtgcgccgccgag tacctggcgctgtatcagaaactcatcaaacctgcccactggaaagcctacctggcagcc aggggcgtcctgccctatatcggcagcctcatcactaaggaaatagctcgtttactcgcc ttggaggaagcaacactcagcactgatttgcagcagggttacgccttgaagagtctcaca ggtcttctctcttcctttgtggaggtggagtccatcaaacggcacttcaaaagccgcctg gtgggtacggtgctgaatggttacctgtgcttgaggaagttagtggtacagagaacaaag ctgatcgatgaaacccaggacatgctgctggagatgctggaggatatgacaacaggcaca gaatctgaaaccaaagcatttatggcagtgtgtatagagactgcaaaacgctacagcctt gatgactacaggactccagtcttcatctttgagagactatgcagtattatctatcctgaa gagaatgaagtgaccgaattctttgtaactctggagaaagatccccagcaggaagacttc ttacagggcagaatgccaggaaatccctacagcagtaatgagcctggcattgggccactc atgagggacatcaagaacaagatctgtcaggactgtgacctggtagctctgctggaggat gacagcggaatggagcttttggtgaacaataagatcatcagtttggatctgcctgtggct gaggtctacaagaaggtgtggtgtcccactaatgagggggagccgatgaggatcatttac cgcatgcgagggctactgggagatgcaacggaggaattcatcgagtctctcgactccact actgatgaagaggaggatgaggaagaggtttataagatggccggtgtcatggcccagtgc ggaggcttggagtgcatgctcaacaggctgaccggcatcaaggacttcaaacaagggcgg cacctcttaaccgtgctgttaaaactctttagttactgtgtgaaggtgaaaataaatcgt cagcagttggtcaagccggagatgaacactttgaatgtcatgctgggaactcttaacttg gctctggtggcagagcaggagagtaaggacagcggaggggcagccgtggccgaacaagtg ctcagtataatggagataattctggatgaatccaacgcggaacctctgagtgaggacaag ggcaacctccttctcaccggtgacaaagatcagctggtaatgttgctcgatcagattaac agcacttttgtccgttccaacctcagcgtcttgcaaggcctgttgcgcatcatcccttac ctgtccttcggggaaatggagaaaatgcagattctggttgatcgattcaagccctactgc aactttgataagtacgacgaggagcacagtggagatgataaagttttcttggactgcttc tgtaaaatagcagcgggaataaagaacaacagcaacggccatcagctgaaagatctcatc cttcagaagggaattacgcagaatgcccttgactacatgaaaaaacacatccccagcgca aagaatttggacgcagacatatggaagaaattcttatctcgacctgcgcttccttttatc ctgcgcctgctccgcggacttgccacccagcaccctgctacacaggtgctaataggtaca gactcaatcaccaacctgcacaaactggagcaggtgtctagcgacgaggggatcgggacg ttagcggagaatcttctggaggcactaagggaacatccagaggtgaataagaagattgac gctgcccggaaggagacgcgcgcagagaagaagcggatggccatggcgatgagacagaag gccttgggcactctggggatgacgacgaatgagaagggtcaggtagtgaccaagactgcg ctgcttaaacagatggaggaacttatagaagagccaggtctgacttgctgcatctgccgg gaaggatacaagtttcagcctacgaaagtcctgggtatttatactttcaccaaacgtgtt gcactagaggagtttgagaacaagccccgaaaacaacagggatacagcacagtctctcac ttcaacattgtccactacgattgtcaccttgcggctgtgagacttgctcgcggccgggaa gaatgggagagcgcagccctacaaaatgccaacaccaagtgcaacgggctcctgcccgtg tggggacctcatgtgccagagtctgcttttgctacttgcttagcacgacacaacacatac ctccaggaatgcacagggcagcgggaacctacctaccagctcaatgtccatgacattaaa ctgctatttctccgttttgcgatggagcaatcattcagcgtagatactggaggaggagga agggagagcaacatacacctcattccctacataatccacacggtgctctacgtcctcaac acaactcgagcgacgtcgagggaggagaaaaacctgcagagcttcatggagcaccccaaa gagaagtgggtggagagtgcctacgaggtggacgggccccactactacaccgtgctggcg ctgcacatctcgccccccgagaagtggaaagccatgcgagtggagatcctcaagaggctc ctcgtcacctcccacgcgcgggtggtgtcaccaggtggagccagcagactggcagataag gcggtgaaggaatacgcaacgtaccgctctggccttctcttctgggccctcgtagatctc atttacaacatgttcaagaaggtgcctaccagtaacacagaggggggctggtcctactct cttgctgaattcatccgacacaacgacatgccaatacacgaagctgcagacaaggccctg aaaaccttccaggaggagttcatgccagtcgaaacgttttccgagtttttggatgtggcc ggactcttgtcagaaatcagtgatcccgacagcttcctcaaggatcttttgaactccatc ccctga

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