KEGG   Colossoma macropomum (tambaqui): 118818810
Entry
118818810         CDS       T09004                                 
Symbol
pik3ca
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
cmao  Colossoma macropomum (tambaqui)
Pathway
cmao00562  Inositol phosphate metabolism
cmao01100  Metabolic pathways
cmao04012  ErbB signaling pathway
cmao04068  FoxO signaling pathway
cmao04070  Phosphatidylinositol signaling system
cmao04081  Hormone signaling
cmao04140  Autophagy - animal
cmao04150  mTOR signaling pathway
cmao04210  Apoptosis
cmao04218  Cellular senescence
cmao04370  VEGF signaling pathway
cmao04510  Focal adhesion
cmao04620  Toll-like receptor signaling pathway
cmao04625  C-type lectin receptor signaling pathway
cmao04810  Regulation of actin cytoskeleton
cmao04910  Insulin signaling pathway
cmao04914  Progesterone-mediated oocyte maturation
cmao05100  Bacterial invasion of epithelial cells
cmao05132  Salmonella infection
cmao05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:cmao00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    118818810 (pik3ca)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    118818810 (pik3ca)
   04370 VEGF signaling pathway
    118818810 (pik3ca)
   04068 FoxO signaling pathway
    118818810 (pik3ca)
   04070 Phosphatidylinositol signaling system
    118818810 (pik3ca)
   04150 mTOR signaling pathway
    118818810 (pik3ca)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    118818810 (pik3ca)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    118818810 (pik3ca)
  09143 Cell growth and death
   04210 Apoptosis
    118818810 (pik3ca)
   04218 Cellular senescence
    118818810 (pik3ca)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    118818810 (pik3ca)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    118818810 (pik3ca)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    118818810 (pik3ca)
   04625 C-type lectin receptor signaling pathway
    118818810 (pik3ca)
  09152 Endocrine system
   04910 Insulin signaling pathway
    118818810 (pik3ca)
   04914 Progesterone-mediated oocyte maturation
    118818810 (pik3ca)
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    118818810 (pik3ca)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    118818810 (pik3ca)
   05100 Bacterial invasion of epithelial cells
    118818810 (pik3ca)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cmao04131]
    118818810 (pik3ca)
Enzymes [BR:cmao01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     118818810 (pik3ca)
Membrane trafficking [BR:cmao04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    118818810 (pik3ca)
SSDB
Motif
Pfam: PI3Ka PI3_PI4_kinase PI3K_C2 PI3K_rbd PI3K_p85B DUF2321 ABC1 Ribosomal_S15
Other DBs
NCBI-GeneID: 118818810
NCBI-ProteinID: XP_036442160
LinkDB
Position
Unknown
AA seq 1070 aa
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDAVELRDANGPHSRALYVYPPNVESSPELPKH
IFGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPMD
NFTMPSYSRRISTATPYMNGEASSKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SSPVKFPDMTTIEDHANWIISREMGYNYCQSGQSSRLARDHIITDADIELQLRQLANRDP
LSEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAM
ELLDCNYPDPMVRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKRALT
NQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDIL
KQEKKDETQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEDCRIMSSAKRPL
WLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCL
SIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGETYDMAIDLFTR
SCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQD
FLIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDD
IAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
NT seq 3213 nt   +upstreamnt  +downstreamnt
atgcctccaaggccgtcatctggagaattatggggcatccatttgatgccccccaggatt
ctggtggattgtctactacctaacggcatgatcctgaccctggagtgcctccgtgaggcc
acgcttatcaccatcaagcatgaactgttcaaggaagccaggaagtaccccctccaccac
cttttacaagaggagacctcctacatttttgtcagcgtaacacaggaggctgagcgggaa
gagttttatgacgagactaggagactctgtgatctcaggctcttccagcctttcctaaaa
gtcatcgaacctgtgggcaacagggaggagaaaattctcaaccgagaaatcggttttgca
attggtatgcctgtgtgcgagtttgatttagtgaaggatcctgaagtgcaggacttcagg
agaaatattcttaatgtctgcaaagatgcagtagaactccgagatgcgaacggaccccat
agtagagcattatatgtttaccctccgaatgtggagtcatcaccagagcttccgaagcac
atctttggcaaattagacaaaggtcagatcattgtagtcatctgggtgattgtgtcaccc
aacaatgacaagcagaagtacaccttgaagatcaaccacgactgcgtccctgagcaggtg
atagcagaagccatcagaaagaagacgcgaagcatgctgctatctgccgagcagctgaag
atgtgtgtgcaggagtatcagggcaaatacatcctcaaagtgtgcggctgtgacgagtac
ctgctggaaaagtaccccatcagtcagtataagtatgtgaggagttgcattatgctggga
cgaatgccaaaccttatgctgatgtctaaggatagcctgtactctcagctgcccatggac
aacttcaccatgccatcctactcgcgccgcatctccacagccacgccatacatgaacggg
gaggcctccagcaaatccctatggaccatcaacagcaccctgaggatacgtgtcctctgt
gccacatacgtcaatgtgaacatccgggatattgataagatttatgtccggacaggaatc
taccatggaggagagcagatgtgtgacaacgtaaacacgcaacgtgtaccctgttcaaac
ccaaggtggaatgagtggcttacgtatgacatgtacattcctgacattccccgggctgct
cgtctgtgtttgtccatctgctccgtgaaggggaggaagggcgcgaaagaggagcactgt
ccactggcttggggaaacgtgaacctgtttgactacacgcacacactggtctctgggaag
atggcactgaacctgtggccagtgccacacggcctggaagatctcctgaatcccattggc
gtcacaggctccaaccccaacaaggaaaccccttgtcttgagctggagtttgactacttc
agcagtcctgtgaagttccctgacatgaccacaatagaggatcacgctaattggatcata
tccagagagatgggatacaattactgccagtctggacagagtagcagactggctcgtgac
cacatcataacagatgctgatattgagttgcagctgcggcaactggccaaccgagaccca
ctttctgagatcactgagcaagagaaggacttcctgtggaggcacaggcaatattgtgta
aatatacctgagatccttcctaagattctgcttgcagtcaaatggaactccagggatgaa
gtcgcacagatgtattgcctgctgaaagactggcctgcaataaaaccagaacaagccatg
gagttgcttgattgcaattacccggatccgatggttcgagactttgcagtacggtgcctt
gaaaagtatttgactgatgataaactgtcccagtaccttattcagttggttcaggttttg
aagtatgagcagtatctcgacaacccattggtgcgatttctgctaaaaagggccctaacc
aaccagaggattgggcatttctttttctggcatttgaagtcagagatgcacaacaaaaca
gtgagccagcgcttcggcctgctgctggagtcatactgtcgagcctgcggcatgtacctg
aagcacctcagcaggcaggtggaggccatggagaaactcattaacctcacagacatcctc
aagcaggaaaagaaggatgaaacccagaaggtgcagatgaagtttctggtggagcaaatg
aggaggccagactacatggatgcacttcaaagcttcacctccccactcaacccagcccac
cagctggggaacttaaggcttgaagactgcagaattatgtcatcagccaagaggccactg
tggcttaactgggagaaccctgacataatgtcagagcttctcttccagaacaatgagatt
atcttcaagaatggtgatgacttaaggcaagatatgttgacgcttcagatcattaaaata
atggagaacatctggcagaaccagggactcgatctcaggatgcttccctatggctgctta
tccattggggattgtgtgggtctgattgaagttgtgaggagctctcacaccatcatgcaa
atccagtgcaaaggaggtctcaaaggagcactgcagttcaacagctccacacttcatcag
tggctgaaggacaaaaacaagggagagacgtatgatatggccattgacctgtttacgcga
tcctgtgctggctactgtgtggccaccttcattctgggcatcggtgacagacacaacagt
aatattatggtgaaggacgatggacagctatttcacatagattttgggcacttcttggat
cataagaagaagaagtttgggtacaagcgagagcgagtcccgtttgtcttaacgcaggac
tttttaatagtgattagcaaaggaggaactcaagaatgcaccaagacgagggagtttgag
aggttccaagagatgtgctacaaggcgtacctggccattcggcagcatgcaaacctgttc
atcaacctcttctccatgatgcttggctcaggaatgcctgagttgcagtcttttgatgac
attgcctacatccgtaagactcttgcgctggacaagacggaacaggaggctttggactac
ttcatgaagcagatgaacgacgctcatcatggcggatggaccaccaagatggactggatc
ttccacaccatccgacaccatgcccagaactga

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