Corynebacterium matruchotii: HBA49_08035
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Entry
HBA49_08035 CDS
T07153
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
cmat
Corynebacterium matruchotii
Pathway
cmat00290
Valine, leucine and isoleucine biosynthesis
cmat00620
Pyruvate metabolism
cmat01100
Metabolic pathways
cmat01110
Biosynthesis of secondary metabolites
cmat01210
2-Oxocarboxylic acid metabolism
cmat01230
Biosynthesis of amino acids
Module
cmat_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
cmat00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
HBA49_08035 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
HBA49_08035 (leuA)
Enzymes [BR:
cmat01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
HBA49_08035 (leuA)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
QIP45463
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Position
2487776..2489602
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AA seq
608 aa
AA seq
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MAIHDTFISAPTSDITKPAGEPPADQPKWNKQRGSAMPAHRYQPFAQEVEDVTLPDRTWP
DNKITHAPAWCAVDLRDGNQALIDPMSPERKRRMFNLLVQMGYKEIEVGFPSASQTDFDF
VREIIEQDMIPDDVTIQVLVQAREHLIRRTFEACEGAKNVIVHFYNSTSILQRNVVFRKD
KAAIKKLATDAGELIKTIAKEYPDTNWRWEYSPESFTGTELAYAKEVVDAVVEVMDPTPE
NPIIINLPSTVEMITPNVYADAIEWMHRNLNRRDSIILSLHPHNDRGTGVASAELAFMAG
ADRIEGCLFGNGERTGNVCLVTLGLNLLTQGVDPQIDFTNINQIRSTVEYCNQLRVPERH
PYGGDLVFTAFSGSHQDAVNKGLDAMAARVHPGANHSDVKWEQLRDELWEVPYLPIDPKD
VGRNYEAVIRVNSQSGKGGVAYIMKTDHGMVLPRPMQVEFSSVVQDVTDAQGGEIESKAM
WDIFAETYLDATTPLEQVAMRVDAAVTERDQAKITAELRFQGESVTVSGTGNGPIAAYAN
ALEQLGIDVEVQEYTQHARTAGDDAEAAAYIFADVNGQKVWGVGIAGSITYASLKAVTSA
VNRAYQAF
NT seq
1827 nt
NT seq
+upstream
nt +downstream
nt
atggccatccatgacacttttatttccgcccccactagcgacatcaccaaacctgccggg
gagccgcccgcagaccagccgaaatggaataagcagcgcggttccgccatgccagcgcac
cgctatcagccgttcgcccaggaggttgaggacgtcaccctgccggaccgcacctggccg
gataataagatcacgcacgcgccagcctggtgtgcggtggatttgcgggacggaaaccag
gcgctgattgatccgatgagcccggagcggaaacgccgcatgtttaacctgctggtgcag
atgggttacaaagagattgaggtggggttcccgtcggcgtcacaaaccgatttcgatttt
gtccgggagatcatcgaacaggacatgatcccggacgatgtgaccatccaggtgctggtg
caggcccgggagcacctgattcgccgcacattcgaggcctgcgagggtgccaagaatgtg
attgtacacttctataactccacatcgattttgcagcggaatgtggtgttccgtaaggac
aaagccgcaatcaagaaactggccacggatgccggcgaattgattaaaacgatcgccaag
gaatacccagacacgaattggcggtgggagtattccccggagtcgtttaccggcaccgaa
ttggcgtatgcgaaggaagtggtggacgcggtggtggaggtcatggaccccaccccggag
aatccgatcattattaatctgccgtccacggtggagatgattaccccgaacgtgtatgcg
gatgcgatcgagtggatgcaccggaatttgaaccggcgggattccattattttgtcgctg
cacccgcataacgatcggggcaccggggtggcttccgccgagctggcgttcatggccggc
gcggaccggatcgagggctgtctgtttgggaatggcgaacgcaccggcaacgtgtgcctg
gtcacactggggttgaatctgttgacgcagggtgtggatccgcagattgatttcaccaat
atcaaccagattcgctccacggtggagtactgcaaccagctgcgggtaccggagcggcat
ccctacggcggtgacctggtgtttaccgcgttctccgggtcgcaccaggatgcggtgaat
aaggggctggatgcgatggccgcccgggtgcatccgggcgcgaaccacagcgatgtgaag
tgggagcagttgcgggacgaactgtgggaggtcccctacctgccgatcgacccgaaggat
gtgggccgaaactacgaggcggtgattcgagtgaattcgcaatccggcaagggcggcgtg
gcctacatcatgaagacggatcatggcatggtgctgccgcggcccatgcaggtggaattc
tcgtcggtggtgcaggacgtcaccgatgcgcagggcggcgagattgagtcgaaggccatg
tgggacattttcgccgaaacctacctggatgcgaccacccccctggagcaggtggccatg
cgtgtggatgcggcggtgacggagcgggaccaggcgaagatcacggccgagctgcggttc
caaggggaatcggtgacggtcagtggcacgggcaacggtccgatcgcggcgtacgcgaat
gcgctggaacaattggggattgatgttgaggtgcaggaatacacccagcacgcccggacc
gcgggtgatgacgcggaggccgccgcctacattttcgccgacgtgaacggccagaaggtg
tggggtgtgggcatcgccggatctatcacctatgcgtcgctgaaggcggtcacgtcggcg
gtgaaccgcgcataccaggctttttaa
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