Cucurbita maxima (winter squash): 111481402 Help Entry 111481402         CDS       T05246                                  Name (RefSeq) DNA topoisomerase 2 isoform X1   KO K03164   DNA topoisomerase II [EC:5.6.2.2] Organism cmax  Cucurbita maxima (winter squash) Brite KEGG Orthology (KO) [BR:cmax00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:cmax03032]     111481402    03036 Chromosome and associated proteins [BR:cmax03036]     111481402 Enzymes [BR:cmax01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.2  DNA topoisomerase (ATP-hydrolysing)      111481402 DNA replication proteins [BR:cmax03032]  Eukaryotic type   DNA Topoisomerases    111481402 Chromosome and associated proteins [BR:cmax03036]  Eukaryotic type   Chromosome condensation proteins    Other regulators of chromosome condensation     111481402   Centrosome formation proteins    Centriole proteins     111481402 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DNA_topoisoIV TOPRIM_C DNA_gyraseB Toprim HATPase_c Motif Other DBs NCBI-GeneID:  111481402 NCBI-ProteinID:  XP_022982562 UniProt:  A0A6J1IWX9 LinkDB All DBs Position Unknown AA seq 1491 aa AA seqDB search MAVEKRPLQNSNAANVDSDPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWI YENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSLKVVIDAEQNCISVFNNGDG VPVEVHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG RRLKKYKQVFSDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRV LDLAGCLGKTVKVELNGQRVPVKSFQDYVDFYLKSAAAFQTEPPKRYHIRPNERWEIVVT LSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF INALIDNPAFDSQTKETLTIRQSSFGSACELTPDFLKNVATKSGIMDSVLSWVNFKQSKD LKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGV FPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDG SHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYEAWKDNLRG NASGWSIKYYKGLGTSTSKEGREYFEQLAKHKKDFIWQDEHDGEAIELAFSKKKIEERKN WLRQFEAGTHLDQSEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFK RNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNH GGKDHASSRYIYTKLSNATRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEG IGTGWSSYIPNYNPRDIIRNVRRMLDGEAMLPMDPWYRGFSGTIEKTATKEGGTSYTVSG IIEEVSDTTLRITELPVRRWTNDYKDFLDSVTRVSTKNDKDKEKAAKDPFIEQADHHSDD KTVSINVHLTEENMILAMQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFF PLRLEFFEKRKRNLLENLETELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQEKGFT PFPKKTKSVEPEVAGASNETDEAEESPEVVKGERVSDYEYLLALAIGTLTIEKVQELCNE RDKFKGEVEELRKATPKSLWLKDLDYLEKELDEMDRNDAQADEVRKQQRIKNNDIKPKIS RNAPKAPRNSKKTSNSETITESMDIATSSSTTTEVANNPVVKPKGKAAPRKAPAKKQGKA AVLDDDGDDEVLELKDRLAAYKLESSPEPSEVSAMETEVPKVQAAAKKKEPSKRAAAKKK TTAKSAQISDDSDDGDFEIKEIAPPAAKKGGGRKAAANAKTTKTTKKQEPVARLGQKLIT QMLEPTENSGISPEKKVRKIRESPFNKKSGSVLGRKIGEEEEEVEEAGNEGKMMGSASSE TTDEEVARVPLARGRSQRTNRTQVRYVVSDSDSEPVYEDSDFDEEADLDED NT seq 4476 nt NT seq  +upstreamnt  +downstreamnt atggccgtggagaagcgcccattgcagaacagcaacgccgccaatgtcgactccgatccg gcgggaccaaagaaaacaatcgaagaaatgtaccagaagaagactcagctagagcacatc ctcctcagacccgatacctatgtcggatcaatcgaaaagcacactcagaacctctggatt tacgagaacgacaagatggtccaccgatccgtcacctatgtgcctggtctttacaagatc tttgatgaaattttggtcaatgctgcagataataagcagagagacccctcgatggactcg ctcaaggttgtgattgacgccgagcagaattgtatcagtgtgttcaacaatggagatgga gttccggttgaagttcatcaggaagagaaggtttatgtgcctgagttgatcttcggacat ctgttgactagtagtaactatgatgatactgagaagaaaaccactggtggacgcaacggc tacggtgcaaaacttacgaatattttttctactgaatttgtgatcgagacggcagatgga agacgtctgaagaagtataagcaggtattctctgataacatggggaaaaaatctgagccg atcataacaaagtgcaaggagggtgataattggaccaaggtgacttttaagccagacttg gctaagttcaacatgactcatcttgaagatgacgttgttgcactgatgaaaaagagagtg ctggatttggccggatgcctcggtaaaaccgtgaaagttgagctaaatggacaaagggtc cctgttaaatcgtttcaagattatgtagatttctatctcaaatcggcagccgcattccag acagaacctccaaaaaggtatcacattcggcctaatgagagatgggaaatcgtggtgacc ttaagtgagggccaattccagcaggtcagctttgtgaacgggattgcaactatcaagggt gggactcatgttgattacattactaatcaaatagcaaattatgttatgactgttgtaaat aagaagaacaaaaatgctaacgtgaaggcccacaacgtgaagagctatttgtgggttttt atcaacgccctcattgataatcctgccttcgattcccaaaccaaggaaaccttgacaatt cgtcaaagcagcttcggctctgcatgcgaacttacgccagacttcttgaagaacgtggcc acgaaatctggcattatggatagtgttctctcgtgggttaatttcaagcaaagcaaagac ctgaagaaaacggatggagcaaaaacagaaaagattagtggtatagaaaagttggaggat gccaattgcgctggagggaagaattcggaaaaatgtaccttaattttgacagaaggagat tcagccaaggcccttgcgatggctggtctcggtgtagtaggtcgagatttttatggcgta ttcccactgagaggtaaattgctcaatgtgagggaagcaagcagtaaacagatcactgag aataaagaaattcaatacatcaagcaaattcttggacttcagcaagggaaggaatacaac aacgctaaggctttgagatatggtcatttgatgattatgaccgatcaggatcacgatggt tcgcacattaaagggctcttgatcaactttattcattctttctggccttccctcttaaga gtgccgtcgtttttggttgaattcataacgcctattgtcaaggctactcataggaatgga actgttttatcattctataccatgcccgagtacgaggcttggaaagataacttaaggggc aatgcaagtggctggtcaatcaagtactataaggggttgggaacaagcacatcgaaagaa ggaagagagtacttcgaacagctggcaaagcacaagaaagattttatttggcaagatgaa catgatggggaggcgattgagcttgctttcagtaagaagaagattgaagagaggaagaat tggctccgtcaatttgaggctggtacccatctagatcagtcagaaaaattgatcaaatat agcgacttcgtcaacaaggagcttatattattttcaatggctgatttacaaaggtctatt ccctcaatggttgatggccttaaacctggccaaaggaagatccttttctgttctttcaag agaaactttatcaaagaggcaaaggtttctcaattttccggttatgtatctgagcattct gcttatcatcatggtgagcagagtcttgctagtaccatcattggaatggcacaggacttt gttggcagcaacaacattaatcttcttctaccaaatggacagtttggcacacgaaaccat ggaggcaaagatcatgcaagttctaggtacatttacactaaactttcaaatgctacacga ttccttttcccgaaagacgatgacaaacttctaaactacttaaatgaagacggccagtcg attgaaccaacctggtatatgcctatcataccaaccgttcttgtcaacggaagtgaggga ataggaactgggtggagttcttacattccaaattataatcctagagacatcattagaaat gtaagacgcatgttggatggtgaagccatgttgccaatggatccctggtatagaggtttt tcaggaactatagagaaaactgccactaaagaaggaggtactagttacactgttagtgga attattgaggaagtcagcgacacgacgttaagaataaccgagttgccagttcgccgatgg actaatgattacaaggactttcttgactctgtaacaagagtttcaacaaagaatgacaaa gataaagaaaaagcagcgaaggatccttttattgagcaagctgatcaccacagcgatgac aaaactgtttccattaatgttcacttgacggaggaaaacatgatactggccatgcaggaa ggtttgaagaagaaattcaaattaactactactgttagcactagcaacatgcatctgttt gatgcaaatggcgtgattaagaaatatgacaccccagaacaaattcttgaggaattcttc ccccttagacttgaattctttgagaaaagaaagagaaatcttttggaaaaccttgaaacg gagttgctcaaactggaaaacaaggtgaggtttatccttgctgttgtgaatggagagata atagtaagcaatagaagaagagtagatttgttccatgagcttcaagagaaaggctttaca ccctttcctaagaagactaaatccgttgagccggaggttgctggggcatcaaacgaaaca gatgaggcagaggagagtccggaagtagtaaaaggggaacgagtcagtgattacgagtat ctactcgctctggcaatcggaaccttgaccatcgagaaggttcaggagctatgtaatgag agagacaaattcaaaggggaagtggaagagctgaggaaggcaaccccgaagtctttgtgg ctgaaagatcttgattatctcgagaaggaacttgatgagatggatagaaatgatgctcag gcagatgaggtaagaaaacagcagagaataaaaaataacgatataaagccaaaaatctct agaaatgcaccaaaagccccacgcaacagtaagaagaccagcaattcagaaaccatcacg gaaagtatggacatagcaacatcaagttctacaacaacggaagttgcaaataacccggtg gtgaagcccaaaggcaaagcagctccaagaaaagctcctgctaaaaagcagggtaaagct gcagttcttgacgacgacggtgacgacgaagtccttgagcttaaagatcgtcttgctgcc tacaaacttgaatcatctcctgaaccatcagaagtttcagccatggaaactgaagtgccg aaagtacaagcggcggccaagaagaaagaacccagcaagagagcagctgccaagaagaaa actacagcaaagtctgctcagatttccgatgacagcgatgacggggacttcgaaataaag gagatagcccctccagcagccaagaagggaggaggaagaaaggcagctgcaaatgccaaa acaaccaaaacaaccaagaagcaagagccggtggcgaggttgggtcagaaactgataact cagatgctggagccaactgagaactccggcatctcaccggagaagaaagtgaggaagata agagaatcacctttcaacaagaaaagtggctctgtgttgggaagaaaaattggggaagag gaagaggaagtagaagaagctggaaatgaagggaagatgatgggttctgcttcttctgag actactgatgaagaagtcgcccgagttccactggcgagaggaagatcacagaggacaaac agaactcaggtcagatatgtggttagtgattctgatagcgaaccagtttatgaggattcc gacttcgatgaagaagcggacttggatgaagattga

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