KEGG   Corynebacterium minutissimum: NCTC10288_02277
Entry
NCTC10288_02277   CDS       T05574                                 
Symbol
rmlB
Name
(GenBank) dTDP-glucose-4,6-dehydratase
  KO
K01710  dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
Organism
cmin  Corynebacterium minutissimum
Pathway
cmin00521  Streptomycin biosynthesis
cmin00523  Polyketide sugar unit biosynthesis
cmin00525  Acarbose and validamycin biosynthesis
cmin00541  Biosynthesis of various nucleotide sugars
cmin01100  Metabolic pathways
cmin01110  Biosynthesis of secondary metabolites
cmin01250  Biosynthesis of nucleotide sugars
Module
cmin_M00793  dTDP-L-Rha biosynthesis, Glc-1P => dTDP-L-Rha
Brite
KEGG Orthology (KO) [BR:cmin00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00541 Biosynthesis of various nucleotide sugars
    NCTC10288_02277 (rmlB)
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    NCTC10288_02277 (rmlB)
   01055 Biosynthesis of vancomycin group antibiotics
    NCTC10288_02277 (rmlB)
  09110 Biosynthesis of other secondary metabolites
   00521 Streptomycin biosynthesis
    NCTC10288_02277 (rmlB)
   00525 Acarbose and validamycin biosynthesis
    NCTC10288_02277 (rmlB)
Enzymes [BR:cmin01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.46  dTDP-glucose 4,6-dehydratase
     NCTC10288_02277 (rmlB)
SSDB
Motif
Pfam: GDP_Man_Dehyd Epimerase 3Beta_HSD RmlD_sub_bind NAD_binding_4 Polysacc_synt_2 NAD_binding_10 NmrA adh_short Sacchrp_dh_NADP adh_short_C2
Other DBs
NCBI-ProteinID: SQI00954
UniProt: A0A2X4US74
LinkDB
Position
1:2444495..2445490
AA seq 331 aa
MLVTGGAGFIGANFVRLVAQQRPEVKITVLDKLTYAGNRANLAGVDATLVVGDVADEGVV
DKLVAHADVVVHFAAESHNDNSLRDPSPFLHTNVMGTFVLLEACRRHDVRFHHVSTDEVF
GDLEIGADTYFTEETPYNPSSPYSATKAGSDHLVRAWVRSFGLRATISNCSNNYGPYQHI
EKFIPRQITNLLLGQPAKLYGTGEQVRDWIHVDDHNEAVLAILDRGQIGETYNIGADQED
TNNRQVIEMICELMGATDGDRANYIHVADRPGHDQRYAMDASKLRRELGWTPRYTDLREG
LAATIEWYRANEDWWRAGKEEVEANYAKQGQ
NT seq 996 nt   +upstreamnt  +downstreamnt
atgcttgtgaccggcggcgccggttttattggggcaaacttcgtcagactcgtcgcccag
cagcggccagaggtgaagattaccgtcctcgataagctcacctacgcgggcaaccgcgcc
aacctcgccggcgtggatgccacgcttgtggtgggcgatgtggcggatgagggggtcgtc
gacaagctcgtggcccacgctgatgtcgtggtccatttcgccgccgagtctcacaatgac
aactcattgcgggatccttcgcccttcctccacaccaacgtgatgggcaccttcgtgctg
ctggaggcttgccgccgccacgatgtgcgcttccaccacgtctctaccgatgaggtcttc
ggggacctagagattggcgcggatacctacttcaccgaggaaactccctataacccttcc
tcgccctattcggccacgaaggccggctcggatcacttggtgcgcgcatgggtacgcagc
tttgggctgcgggcaactatttcgaattgctccaataattacggcccttaccagcacatt
gagaaattcatcccgcggcagatcactaatctgctcctgggccagccggccaagctttat
ggcaccggcgagcaggtgcgggattggattcacgtggatgaccacaacgaggccgtactc
gccatcttggaccgcgggcagattggtgagacgtataacatcggcgccgaccaggaggat
accaataaccgccaggtcatcgagatgatttgtgagctcatgggggctactgacggcgac
cgagcgaactacatccacgtggcggaccgcccgggccatgaccagcgctacgccatggac
gccagtaagctgcgccgcgaactgggctggaccccgcgctatacggacctgcgggagggc
ctcgccgccaccatcgagtggtaccgcgctaacgaggactggtggcgcgcgggcaaggaa
gaagtcgaagccaactacgccaagcaaggacagtaa

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