KEGG   Cryptococcus neoformans var. neoformans JEC21: CNK01430
Entry
CNK01430          CDS       T00243                                 
Name
(RefSeq) DNA polymerase epsilon, catalytic subunit a, putative
  KO
K02324  DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
Organism
cne  Cryptococcus neoformans var. neoformans JEC21
Pathway
cne03030  DNA replication
cne03410  Base excision repair
cne03420  Nucleotide excision repair
Brite
KEGG Orthology (KO) [BR:cne00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    CNK01430
   03410 Base excision repair
    CNK01430
   03420 Nucleotide excision repair
    CNK01430
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:cne03032]
    CNK01430
   03400 DNA repair and recombination proteins [BR:cne03400]
    CNK01430
Enzymes [BR:cne01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.7  DNA-directed DNA polymerase
     CNK01430
DNA replication proteins [BR:cne03032]
 Eukaryotic type
  DNA Replication Elongation Factors
   DNA polymerase epsilon complex
    CNK01430
DNA repair and recombination proteins [BR:cne03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    Long Patch-BER factors
     DNA polymerase epsilon complex
      CNK01430
SSDB
Motif
Pfam: DUF1744 POL2_thumb DNA_pol_B_exo1 DNA_pol_B zf-DPOE zf_DPOE_2 DNA_pol_B_exo2 RNase_H_2 NAPRTase_C Zn_ribbon_RPB9 zf-RRPl_C4
Other DBs
NCBI-GeneID: 3254656
NCBI-ProteinID: XP_567821
UniProt: P0CN26
LinkDB
Position
11:join(417347..417658,417730..417855,417904..417999,418073..418382,418436..418740,418802..419007,419063..419354,419414..419599,419655..422777,422828..424342,424392..424481,424542..424668,424724..424788)
AA seq 2250 aa
MPSRGSFRGRGRGSGSGFGSNTRFTGRRRGRGGGGGGGGVAYGIDRRPATSTNQANREDG
TAATEKFEEVKVYDEIDEKIGFWRFESVRAEGEEKVGWLVNMHQTLVPSDVHPGGLAAVD
YYFIQDDGGSFKVSIPYEPYFYLTCRGGTESIVEEWLLKRYEGIIIRIEREKKWDLSLPN
HLLSAPPVFLKLFFHNTADLQTIRRDLLPLARSNSEKFTAVDAYADVVSAEAAANGHGDD
ENRAWGAEDDTKKKKDKEPSECIIEVREHDLAYHLRVAIDLNIRVGLWYTVTSRTGVITL
ERIPDRVKRADPVVMAYDIETTKQPLKFPDQQTDQIMMISYMIDGMGYLITNREIVGEDI
DDFEYTPKDEYPGEFTVFNEPDEPAVIRRWFEHIRDSKPTVIATYNGDSFDFPFVDARAK
IHGISMYEEIGFKPDIEEEYKSRSTMHMDCFRWVKRDSYLPQGSQGLKAVTTAKLGYNPI
ELDPELMTPYAIEQPQILAQYSVSDAVATYYLYMKYVHPFIFSLCNIIPLSPDEVLRKGT
GTLCETLLMVEAYDAHIIMPNRHEDPHGVTYEGHLLASETYVGGHVEALEAGVFRSDIPT
HFKIVPSAIQELIDDLDAALRFSLIEEGQVKLEDVENYDEVKQQIQTALETMRDEPNRFD
NPLIYHLDVAAMYPNIMLSNRLQPDSVKEEADCAVCDYNRPDKKCDRRMEWAWRGEYFPA
KRDEVNMVRYALEQETFPPKRPYDPKRRFVDLTPTEQSALLHKRLGDYSRKVYKKTHDTK
IVTKTTIICQRENSFYIDTVRAFRDRRYEYKGLHKTWKKNLDKAFEEGGAVATVDEAKKM
IVLYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGITCLTGATIIQMARQLVEQIGRPL
ELDTDGIWCMLPGVFPEDFNFKLKNGKKFGISYPCTMLNHLVHAQFTNDQYHELVNNDSG
TYNVKKENSIFFELDGPYKAMILPSSKEEDKLLKKRYAVFNPDGSLAELKGFEVKRRGEL
QMIKIFQSQIFDKFLLGKTTEECYAAVATVADQWLDILQSKASSLHDDELVDLIAENRSM
SKTLAEYAGQKSTSISTARRLAEFLGEQMVKDKGLSCRFIISAKPNGAPVTERAVPVAIF
TAEEPVKRHYLRKWLKDNSLTDFDLRTILDWDYYTERLGSVIQKLITIPAALQKVPNPVP
RIRHPDWLYKRIATKEDKFQQHKITDMFTKLKDMEDLGDGQKKVGPKLAVVRRRNRKEQE
KESEVEEVPPEPEYDYAGYIRIMKKKWRKQRQEKARARKSGLRQDGTISSMLRTQTSSMN
SKQWDVIQIASTNRPGEFKLWLAIDGTFQSVRLKVPREFYLNFKEDPEPQMLATDRYEAV
EVVRTLPRGQPARHLYKLSVDEVLFMEGESHFSTLINNPNVDGAFELQVPLVVRALLSLG
TSCALRSNILGGLNRGLDKGFDLVDLERSGNLSRRKYLNEGRGIRYHFLFHAVADQRHII
GLFSPDSTNASIYLVDRAKNRQQLPNPLKFYTDRVERAERGVFSYPDMLDFTTSYHSSES
SAFKALGKDLQAINHGLNVIALCSPFEHSYYQAKAPVYSNFPFITYRLGKEEDPGLMWLL
QTSRRMIGLYLRLSSWLKEQIQIASHFDVPIGNLGADIAVFLADIEFARRLKQQDMLIWW
SSTPRPDLGGSEEDANSSEDLVSPHISNRGCYSSTVLEMEVSDLAINAVLQSALVNEMEG
SGTGSLAFDSASHNLDEYAKGAVNTSVMLGDAVLSTQTFGVLKSMLRAWYADKARAHVKG
DSLSPAEIVVDQFWRWISSSTSSMFEPALHRFLHGLMRKTFLQLLAEFKRLGTQVVYADF
GRVFLLTSKPDAGSAFAFAKYLVAAANSQELFRHLIIDVAQFWNYLAWMDVANFGGVKVS
PETAASREPPAKRFEISMDWNIQSFLPGTLQPVFERNVASFIFSLYSAKRSSSDGREPLR
VIHSLNIDQPGTEATSTMNPTKEKEKKAASKSISQTLTRRLLSDIAAVKRQQAAVHLEPE
EAYTLAFPDLPGARSKRINPTLELIKAITEVYSLASEHSIEVQILKRNLLDLIGVKEFSS
DAAFNPPCESIEVPMVICKKCNAIRDVDLCRDPDRLPSVNPDSGEMLEPARKNWVCHKCD
SEYDRFQIEQPLIEMVTKTITNYQIQDVICLKCSQTKSDNLAATCKCGGGFRTTSNRNEL
KTKLKMIKSVCDYHKLPFAGSYVEETLSRW
NT seq 6753 nt   +upstreamnt  +downstreamnt
atgccctccagaggatctttcagaggacgcggtcggggatccggatccggatttggaagc
aacacccggtttacaggcaggcgacggggtcgaggcggaggcggcggcggcggtggtgtc
gcatatgggatcgaccgccgccccgctacatctactaatcaagctaatcgtgaagatgga
accgccgccaccgaaaaatttgaagaggtcaaggtctacgatgagattgatgaaaagatt
ggattctggaggtttgagagtgtgagggcagagggcgaagaaaaggtcggctggttggtc
aatatgcaccagacacttgtgccgagcgatgtgcaccctggaggtctagcggctgtcgac
tactatttcatccaagatgatggaggctcattcaaggtgtccataccttacgagccgtat
ttctatcttacctgtcgggggggaacagagagcatcgtcgaggaatggcttttgaaacga
tatgaaggtatcatcataaggatagaaagagaaaaaaagtgggatctaagcctcccaaac
caccttttatcggcacctccagtattccttaaactgttcttccacaatactgccgatctc
cagactatccgacgtgacttgctacctcttgcacgcagcaactctgaaaaattcacggcc
gttgatgcgtatgccgatgtggtcagtgcggaggcggcagccaacggtcatggggatgac
gaaaacagagcatggggtgcagaggacgacacgaaaaagaagaaggataaagagccgtca
gaatgtatcattgaagtccgagaacatgacttggcgtaccatttacgagtggcaatcgat
ctcaatattcgtgtcggactctggtataccgtcacctcccgcacgggcgttataacgctg
gaacgaatacccgatcgtgtcaagcgtgcggacccagtcgtcatggcgtatgatatcgaa
acaacaaagcagcccctcaagtttccagatcaacaaacggaccaaatcatgatgatttct
tacatgattgacgggatgggctacttgatcacgaatagagagattgtgggtgaagacatt
gatgattttgaatatacaccaaaggatgagtatcccggtgaattcacagtgttcaacgag
cctgacgagcctgcggttatccggagatggtttgaacatatcagagattccaagccaacc
gtcatcgcaacgtataacggtgatagtttcgattttccttttgtcgatgcaagggccaag
atacatggaatcagcatgtacgaggaaattggattcaaaccagatatcgaggaagaatac
aagtcccgatcaaccatgcacatggattgtttcagatgggtcaaacgagactcgtatctt
ccacaaggtagtcagggcctcaaagctgtgactactgccaaactcggatacaaccccatc
gaactcgacccagaattaatgacgccgtacgccatcgagcaaccccaaatattggctcag
tattccgtctccgacgcggtcgccacatactacctctacatgaaatacgttcaccccttc
atcttttcgctgtgtaacatcatccctttaagtccagatgaagtgttgcgtaaaggaaca
ggtacgctctgtgaaaccttattgatggttgaagcttatgatgctcatatcattatgcct
aaccgtcatgaagatccccacggagtgacatacgagggccacctactcgcgtctgaaaca
tatgtcggaggccatgttgaggctctggaagctggtgtgttcaggagcgacatcccgact
cacttcaagatcgtgccaagtgccatacaagaacttattgatgatctcgatgcggcactc
cgattctccttgattgaagaaggtcaagtcaaactcgaggatgtagaaaactacgacgag
gttaaacagcaaatccagaccgctctcgagaccatgcgggacgaacccaatcgcttcgac
aaccctttgatctaccatcttgatgtcgccgccatgtaccccaacatcatgttgtcaaac
cgtctacagcccgattcagtcaaagaggaagcagattgcgcagtgtgtgactacaatcga
cctgacaagaagtgtgatcggcgtatggaatgggcatggagaggagaatacttccccgcg
aaaagagacgaagttaacatggtacgctatgctctggaacaggaaacgttccctccaaaa
cgtccatatgacccaaagcgccgttttgtcgacttgacgcccacagaacaatctgccctt
cttcacaagcgtttaggggactattctcgaaaggtatacaagaagactcacgacacgaag
attgtcaccaagacgacaatcatttgccagcgagagaactcgttctatatcgatactgtc
cgggcattccgagaccgtcgttacgagtacaagggtctccacaaaacctggaagaaaaac
ctcgataaggcatttgaagaaggtggcgcggttgcaacagtagatgaggccaagaagatg
attgtactctacgactcgctccagcttgcacacaagtgtatcctcaactctttctacggt
tatgtcatgcgaaaaggagcgaggtggtattcgatggaaatggcaggcattacttgtctg
actggtgccactatcattcagatggcaaggcagcttgttgagcagattgggcggccgcta
gagctggatacagacggtatctggtgcatgttgcctggtgttttccccgaggacttcaac
ttcaagctcaagaatggcaagaaatttggcatctcgtatccttgcaccatgctcaaccac
cttgtccacgcacagttcaccaacgaccagtaccacgaacttgttaataacgactctggt
acgtacaatgtcaagaaagaaaactcgatcttcttcgaactggatgggccttataaagct
atgatccttccgtcttcaaaggaagaggacaaattgctcaagaagagatatgccgtcttc
aaccctgacggctccctcgcggagttgaaaggattcgaagtgaagcgtcgaggtgaactt
caaatgatcaagatcttccaaagtcaaatcttcgacaagttcttgctgggcaagacgacc
gaggagtgctacgctgccgtcgccaccgttgccgaccaatggctcgatatccttcaaagc
aaggcctcaagtcttcatgatgatgaattggtcgacttgattgccgagaaccgtagcatg
tcgaaaacactggccgagtacgctggtcaaaagtctacttcgattagcacagcaagaagg
ctggcggagtttttaggcgagcaaatggtcaaggacaaaggtctttcttgtcgattcatc
atctctgcgaaacctaacggtgcgccagtcacggagcgagctgttcctgttgcgatcttc
acagctgaagagcccgtgaaaaggcattatctccgcaaatggctaaaggacaacagtctt
acggactttgatcttcgtactattctcgactgggactattacactgaacgtcttggttcc
gtcatccagaagctcatcaccatccccgccgcccttcaaaaggtaccaaaccctgtacct
cgtatccgacaccccgactggctttataaacgtattgccaccaaagaagacaagttccaa
cagcacaagatcactgatatgttcacaaagttgaaggatatggaagatttgggagacgga
caaaagaaagttggacccaaactggctgtggttaggagaagaaacaggaaggagcaagag
aaggaatcggaggtcgaggaagtcccacccgaacccgaatatgactatgctgggtatatc
aggataatgaaaaagaagtggcgcaagcaaaggcaggaaaaagctcgagcgcgcaagtct
ggtcttcggcaagacggcactatttcctccatgcttcgcacgcagacgtctagtatgaat
tcaaagcaatgggacgtcatccagatcgcctccaccaaccggccgggagaattcaaactc
tggcttgccattgatggcaccttccaaagcgtgcgactgaaggtaccccgagaattctat
cttaacttcaaggaagatcccgagcctcagatgctagctacagaccgctatgaggcggtg
gaggtcgtcaggacattacctcgaggacagcctgccagacatctttacaagctgtcggta
gatgaagtgcttttcatggaaggagaatcgcacttttccactttgatcaacaacccgaac
gtggacggtgcttttgagctccaagttccccttgtcgttcgcgcactcctcagccttggg
acttcatgcgccttacgctctaatatcctggggggtctcaaccgcggcctggacaaaggt
ttcgatctcgttgatttggaacgctcaggaaacctgtctaggcgcaagtatctcaatgaa
ggtcgcgggattaggtaccacttcctcttccatgccgttgctgaccaacgacatatcatt
ggccttttctcccccgattccaccaatgcttctatctaccttgtcgatcgcgccaagaac
cgtcaacagctgcctaatccgttgaaattctataccgaccgagttgagcgtgcagaacgt
ggtgtcttctcttaccccgatatgcttgacttcactacctcatatcattcctcagagtca
tccgcattcaaggcccttgggaaagatctccaagccatcaaccacggtcttaatgttatt
gccctttgttcgccatttgagcattcttactaccaggcaaaggcaccagtctattccaac
ttcccgttcataacatatagactagggaaagaggaagacccaggtctaatgtggctgttg
cagacgtcgaggaggatgattggattgtacttgaggctgtccagctggttgaaggagcag
attcaaattgcatcacactttgatgttcctatcggcaacctgggtgccgatatagcggtg
ttccttgcggatatcgagttcgcacgtagactcaaacagcaagacatgctcatttggtgg
tcatcgactccccgaccagatcttggtggttccgaagaagatgctaactctagcgaagat
ctcgtttctcctcacatctcaaaccgcggctgttactcatccaccgtgctggaaatggag
gtgtccgatcttgctattaacgctgtccttcaatcagctctcgtcaacgaaatggaaggt
tcaggaactggttcgctcgcctttgattcggcatcccataaccttgatgagtacgccaag
ggtgctgtcaacacatcggtcatgcttggagatgccgtactttccacccaaacctttggg
gttcttaagtcaatgcttcgtgcatggtatgctgacaaggctcgagctcatgtcaaaggc
gactcattgtcgcctgccgagatcgttgtcgatcaattttggcgttggatcagttcatca
accagcagcatgtttgagccagctctccatcgtttccttcatggcttgatgcgcaagaca
ttcctgcagctcctcgcagaattcaaacggctgggtacccaagtcgtctacgcggatttc
ggccgtgttttccttctcacctccaaacctgatgctggcagcgcgtttgcatttgcaaaa
tacctagttgccgctgccaactcacaagaattgttccgccatctcatcatcgacgtcgcc
cagttttggaactaccttgcgtggatggatgttgccaatttcggcggtgtcaaagtctca
cctgaaactgcggcgagtcgagagccgccagcgaaaaggttcgagattagtatggactgg
aacatccaatcctttttgcccggcactcttcaacctgtgttcgaaagaaatgtggcgagc
ttcatattttccctttacagtgctaagcgctcgtccagcgatggcagagagcctcttaga
gtcatccacagtctcaacattgatcagcctggtacagaagccacatcaacaatgaatcct
acgaaagaaaaggagaagaaagctgcctccaagagcatctcacaaactcttacccgtcga
cttctttctgatattgctgcggtcaagcgtcaacaagctgctgtgcaccttgagccggaa
gaggcctacaccctggcttttcccgacttgcctggagctaggtcgaaacgcattaatccc
accctcgagcttattaaggccattacggaggtctattctctcgcttctgagcatagcatt
gaagtgcaaattctcaagcggaacttgctggacttgattggtgtcaaagagttctcgagc
gatgcggcctttaatcctccatgcgaaagtattgaggtgcccatggtgatttgcaaaaag
tgtaacgcgatcagagacgtcgacctatgcagagatcccgacaggttgcctagtgttaac
ccagatagcggtgaaatgttggaaccagcgagaaagaactgggtgtgtcataaatgtgac
tctgaatatgatcgattccagatcgaacaacctctcatcgaaatggtcaccaagacgatc
accaactaccaaatacaagacgtgatctgcctcaaatgttcgcaaacgaaatcggacaat
cttgcggcgacctgcaaatgtggtggaggatttaggacgacgtcaaacagaaatgaactg
aagacgaagctgaaaatgattaagagtgtatgtgattaccataaattgccctttgctggt
agttatgtggaagagactttgagtcggtggtag

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