Chionomys nivalis (European snow vole): 130867301
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Entry
130867301 CDS
T11437
Symbol
Pdha1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
cnl Chionomys nivalis (European snow vole)
Pathway
cnl00010
Glycolysis / Gluconeogenesis
cnl00020
Citrate cycle (TCA cycle)
cnl00620
Pyruvate metabolism
cnl00785
Lipoic acid metabolism
cnl01100
Metabolic pathways
cnl01200
Carbon metabolism
cnl01210
2-Oxocarboxylic acid metabolism
cnl04066
HIF-1 signaling pathway
cnl04922
Glucagon signaling pathway
cnl05230
Central carbon metabolism in cancer
cnl05415
Diabetic cardiomyopathy
Module
cnl_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
cnl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
130867301 (Pdha1)
00020 Citrate cycle (TCA cycle)
130867301 (Pdha1)
00620 Pyruvate metabolism
130867301 (Pdha1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
130867301 (Pdha1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
130867301 (Pdha1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
130867301 (Pdha1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
130867301 (Pdha1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
130867301 (Pdha1)
Enzymes [BR:
cnl01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
130867301 (Pdha1)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
130867301
NCBI-ProteinID:
XP_057615099
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All DBs
Position
X:135004889..135020204
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AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLAGAAQKPTSRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLPVRAILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgctgtgtcccgcgtgttggcaggtgctgcgcagaagccgaca
agcagagtgctagtagcttcccgtaattttgcaaatgatgctacatttgagattaagaaa
tgtgaccttcatcggctagaagagggccctccagtcaccacagtgctcaccagagaggat
gggctcaagtactacaggatgatgcagactgtgcggcgaatggagctaaaggcagatcag
ctatataaacagaaaattatccgtggtttctgtcacttgtgtgatggtcaggaagcctgc
tgtgtgggcctagaggccggcataaaccccacggaccatctcatcacagcctatcgagct
catggctttaccttcactcggggcctgcctgtccgagcaattcttgcagagctaacagga
cgaagaggaggttgtgctaaagggaaaggcggatctatgcacatgtacgccaagaacttc
tatgggggcaatggcatcgttggagctcaggtgcccctaggagcagggattgctctggcc
tgcaaatacaatggaaaagatgaggtctgtttgacattatatggtgatggcgctgctaat
cagggtcaaatatttgaagcttacaatatggcagcattgtggaaactaccttgtattttc
atctgtgagaataaccgctatggcatggggacatctgtcgagagagcagcggccagcaca
gattactacaaaagaggagattttattcctggactgagggtagatggaatggatatcttg
tgtgtccgagaggcaacaaagtttgcagctgcatattgtaggtctggtaaggggcccatc
ctgatggagctacagacttaccgttaccatggacatagtatgagtgaccctggagtcagt
tatcgcactcgagaagaaatccaggaagtaagaagtaagagcgaccctattatgcttctc
aaggatagaatggtgaacagcaatcttgcaagtgttgaagaattaaaggagattgatgtg
gaagtgaggaaagaaatcgaagatgctgcccagtttgctacagctgatccagagccaccc
ttggaggaactaggctatcacatctacagtagtgatcctccctttgaagtgcgtggtgcc
aaccaatggatcaagtttaagtcagtcagttaa
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