Chionomys nivalis (European snow vole): 130872775
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Entry
130872775 CDS
T11437
Symbol
Tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
cnl Chionomys nivalis (European snow vole)
Pathway
cnl04217
Necroptosis
cnl04380
Osteoclast differentiation
cnl04620
Toll-like receptor signaling pathway
cnl04621
NOD-like receptor signaling pathway
cnl04630
JAK-STAT signaling pathway
cnl04658
Th1 and Th2 cell differentiation
cnl04659
Th17 cell differentiation
cnl05145
Toxoplasmosis
cnl05160
Hepatitis C
cnl05161
Hepatitis B
cnl05162
Measles
cnl05164
Influenza A
cnl05165
Human papillomavirus infection
cnl05167
Kaposi sarcoma-associated herpesvirus infection
cnl05168
Herpes simplex virus 1 infection
cnl05169
Epstein-Barr virus infection
cnl05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
cnl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
130872775 (Tyk2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
130872775 (Tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
130872775 (Tyk2)
04621 NOD-like receptor signaling pathway
130872775 (Tyk2)
04658 Th1 and Th2 cell differentiation
130872775 (Tyk2)
04659 Th17 cell differentiation
130872775 (Tyk2)
09158 Development and regeneration
04380 Osteoclast differentiation
130872775 (Tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
130872775 (Tyk2)
05160 Hepatitis C
130872775 (Tyk2)
05171 Coronavirus disease - COVID-19
130872775 (Tyk2)
05164 Influenza A
130872775 (Tyk2)
05162 Measles
130872775 (Tyk2)
05168 Herpes simplex virus 1 infection
130872775 (Tyk2)
05167 Kaposi sarcoma-associated herpesvirus infection
130872775 (Tyk2)
05169 Epstein-Barr virus infection
130872775 (Tyk2)
05165 Human papillomavirus infection
130872775 (Tyk2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
130872775 (Tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cnl01001
]
130872775 (Tyk2)
Enzymes [BR:
cnl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
130872775 (Tyk2)
Protein kinases [BR:
cnl01001
]
Non-receptor tyrosine kinases
JAK family [OT]
130872775 (Tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Other DBs
NCBI-GeneID:
130872775
NCBI-ProteinID:
XP_057622994
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Position
4:complement(20580657..20605184)
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AA seq
1184 aa
AA seq
DB search
MVADMPLCGRRAMLEDSRADGTEAQPLVPTESLMVLLHWAGPEGGEPWVTFSQTSLTAED
ICIQIAHKVGITPPCLNLFALYDAQAKVWLPPNHVLDTSRDASLRLYFRMRFYFRNWHGM
SPQEPAVYRCGSPGSEQGVQLLDSASFEYLFEQGKHEFMNDVVSLRDLSSEEEIHHFKNE
SLGMAFLHLCHLALCRGVPLEEMAREISFKNCIPRSFHQHIRQHNALTRLRLRRVFRRFL
RAFRPGHLSQQVVMVKYLATLERLAPRFGSEHIPVCHLEVLDHPERDPCYIQNSGQTTGE
PGPELATRLPTHEVLVTGTRGIQWRPLQIQESARGNSRGNPQGNQSGKKVKAPEVAEQLA
KSPGEPSWTYFCDFQDISHVVLKDCHVRIHLQDNKCLLLCLRSRAEALSFVALVDGYFRL
TADSSHYLCHEVAPPRLLTSIQNGIHGPLMDPFVQAKLWPEGGLYLIQWSTSHLHRLILT
VAHRDSAPNSGPKGLRLRKFPITQQPGAFVLDGWGRSFDSVGDLRVALQGCSLRAGDDCF
PLHHCCLPRPGEISNLLVMRGSSAHTRPPNLSQLSFHRVHQDEITQLAHLGQGTRTNVYE
GLLRVGGPDEGKTDSGCPPEPGGGSGQQLRVVLKVLDPSHHDIALAFYETASLMSQVSHM
HLAFLHGVCVRGSENIIVTEFVEHGPLDVWLRRHRGRVPMTWKMIVAQQLASALSYLEDK
NLVHGNVCGRNVLLARLGLEEGTSPFIKLSDPGVGQGALSREERVERIPWTAPECLSGET
SSLGTATDMWGFGATLLEICFDGDAPLQGRRPSEKERFYTKQHQLPEPSCPELATLTRQC
LTYEPAQRPSFRTILRDLTRLQPQNLVGISAVNADSSASDPTVFHKRYLKKIRDLGEGHF
GKVSLYCYDPTNDGTGEMVAVKALKEGCGPQLRSGWQREIEILRTLYHEHIVKYKGCCED
QGVPGHGEKSVQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHGQHYIHRD
LAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYASD
VWSFGVTLYELLTYCDSRQSPPTKFMELIGVTQGQMTVLRLTELLERGERLPRPDRCPCE
IYLLMKNCWEAEASFRPTFQNLVPILKTAQEKYQGQVPSVFSVC
NT seq
3555 nt
NT seq
+upstream
nt +downstream
nt
atggtggcagatatgcctctgtgtgggcggagagccatgttggaagacagcagggcagat
ggcacggaagctcagcccctggtgcccacggaaagcttgatggtgctgctgcactgggct
gggccagagggcggggagccctgggtcaccttcagccagacgtctctgactgccgaggac
atctgcatccagattgcacacaaagtcggcatcactccaccctgcctgaatctctttgcc
ctctatgatgcacaggccaaggtctggctgcccccaaaccacgtcctagacacatcccgg
gatgcgagcctaaggctgtatttccgaatgaggttttacttccggaactggcacggcatg
agtccccaagagccagctgtgtaccgatgtggttccccagggtcagagcagggtgtgcag
ctcttggactctgcctcatttgaatacctctttgagcagggaaaacatgagttcatgaat
gatgtggtgtctctgcgggacctgtctagtgaggaagagatccatcactttaagaatgag
agcttgggcatggcctttctgcacctctgccaccttgctctctgccgtggtgtccccctg
gaggagatggccagagagatcagctttaagaactgcatccctcgttccttccaccagcac
atccgtcagcacaatgcgctcacgcgcctgcgtctacgcagagtcttccggcgattcctg
cgggcctttcggcctggccacctctcccagcaggttgtgatggttaagtacttggccacc
ctggagcggctggctcctcgatttggctcagagcacataccggtgtgtcatctggaggtg
ctggaccatcctgagagggacccctgctacatccagaacagtgggcagactactggggaa
ccaggcccagagctggccaccaggcttcccacccacgaggtactggtgacaggcaccaga
ggtatccagtggcgtccactacagatccaggaatctgctagaggtaacagcagagggaat
ccccaaggcaaccaatctgggaagaaagtcaaggcccctgaggttgccgagcagctggcc
aagagtcctggggagccatcctggacctacttctgcgacttccaggacatctcccacgta
gtgctaaaggactgtcacgtgcgcatccacctccaggacaacaagtgcttgttgctgtgc
cttcgttcccgggctgaagccctgtcctttgtggccctggtggatggctatttccgcttg
accgccgactccagccactacctgtgccatgaggtggcacccccgcggctgttgaccagc
atccagaacggcatccatgggcccctgatggatccatttgtgcaagccaagctgtggccg
gagggcggcctctacctgatccagtggagcaccagccacctccaccgtctgatcctcact
gtggcccatcgagactcagctcccaacagcggccccaagggtctgcgcctccgaaagttc
cccatcacccagcaacctggagcctttgtgctagatggctggggtcgctccttcgacagc
gtgggggaccttcgggtcgccttgcagggctgctcgctgcgggctggtgacgactgcttc
cctttgcaccactgttgcctgccccggccaggagaaatctccaacctcttggtcatgcgg
ggatccagtgcccacacccggcctcccaacctcagccagctcagcttccacagagttcac
caggatgaaatcacgcagctggcccacttgggtcaaggcacgaggaccaatgtttacgag
ggccttctaagagtgggaggccctgacgaaggcaaaaccgacagtggatgccctcctgag
cctggcgggggcagtgggcagcagctccgagtggtgcttaaagtcctggaccccagtcac
catgacatcgccttggccttctatgaaacagccagcctcatgagccaggtgtcacacatg
cacctggctttcctgcatggtgtctgcgtgcgtggctcagagaatatcattgtgacagag
ttcgtagaacatgggcccctggatgtgtggttacggcgacacaggggccgagtgcctatg
acctggaagatgattgtggctcagcagctggccagtgccctcagctacctggaggacaag
aatctggttcatgggaatgtatgtggccggaacgtcctgctggcgcggctggggctagag
gagggtaccagccccttcatcaagttaagtgatcctggcgtgggccaaggtgccctctcc
agggaggagcgggtagaacgcatcccctggacagctcctgagtgcctgtctggagagacc
agtagcttgggtactgccacggacatgtggggttttggtgccacccttcttgagatctgc
tttgatggggatgcacccctgcagggtcgtcgcccctccgagaaagaacgattctacaca
aagcagcaccagctgcccgagccctcatgcccagagctggccacactcacccgccagtgc
ctgacctacgaaccagcacagcggccatcattccgcaccattttgcgggacctcaccagg
ctgcagccacagaatctagtgggtatctccgctgtgaacgcagactcatcagcatcagac
cccacagttttccacaaacgttatttgaaaaagatccgggatttgggtgagggtcacttt
ggcaaggtcagcctgtactgctatgatccaaccaatgatggcactggcgagatggtggct
gtgaaagcccttaaggagggatgtggtccccagctccgctcaggctggcagcgggagatc
gaaatcctgcggaccctgtaccatgaacatattgtcaagtacaaaggctgctgtgaggac
caaggtgtgccaggccatggagagaagtctgtacagctggtcatggaatacgtccccctg
ggcagccttcgggactacctgccacggcacagcgttgggctggctcagctcctgttgttt
gctcagcagatctgtgagggcatggcctacctgcatgggcaacactacattcaccgagac
ctagccgcgcgcaatgtgcttctggacaatgacaggctggtcaagattggagactttggc
ttagccaaggcagtgcctgaaggccacgagtactaccgcgttcgcgaggacggggacagc
ccggtgttctggtatgccccggaatgtctgaaggagtgcaaattttactatgcgtcagat
gtctggtctttcggagtgaccctgtacgagctgttgacctactgtgactctaggcagagc
ccccccacgaaattcatggagctcatcggcgtcacccagggccagatgaccgtgctgagg
ctcacggagctgctagagcgaggagagcggctgcctcggcctgacaggtgtccgtgtgag
atctatctcctcatgaagaactgctgggaggcagaggcctccttccggcccacgttccag
aatcttgtgcctatcctcaagacagcccaggagaagtaccaaggccaggtgccttcagtg
ttcagtgtgtgctga
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