KEGG   Chionomys nivalis (European snow vole): 130879475
Entry
130879475         CDS       T11437                                 
Symbol
Mapk3
Name
(RefSeq) mitogen-activated protein kinase 3
  KO
K04371  mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
Organism
cnl  Chionomys nivalis (European snow vole)
Pathway
cnl01521  EGFR tyrosine kinase inhibitor resistance
cnl01522  Endocrine resistance
cnl01524  Platinum drug resistance
cnl04010  MAPK signaling pathway
cnl04012  ErbB signaling pathway
cnl04014  Ras signaling pathway
cnl04015  Rap1 signaling pathway
cnl04022  cGMP-PKG signaling pathway
cnl04024  cAMP signaling pathway
cnl04062  Chemokine signaling pathway
cnl04066  HIF-1 signaling pathway
cnl04068  FoxO signaling pathway
cnl04071  Sphingolipid signaling pathway
cnl04072  Phospholipase D signaling pathway
cnl04114  Oocyte meiosis
cnl04140  Autophagy - animal
cnl04148  Efferocytosis
cnl04150  mTOR signaling pathway
cnl04151  PI3K-Akt signaling pathway
cnl04210  Apoptosis
cnl04218  Cellular senescence
cnl04261  Adrenergic signaling in cardiomyocytes
cnl04270  Vascular smooth muscle contraction
cnl04350  TGF-beta signaling pathway
cnl04360  Axon guidance
cnl04370  VEGF signaling pathway
cnl04371  Apelin signaling pathway
cnl04380  Osteoclast differentiation
cnl04510  Focal adhesion
cnl04517  IgSF CAM signaling
cnl04520  Adherens junction
cnl04540  Gap junction
cnl04550  Signaling pathways regulating pluripotency of stem cells
cnl04611  Platelet activation
cnl04613  Neutrophil extracellular trap formation
cnl04620  Toll-like receptor signaling pathway
cnl04621  NOD-like receptor signaling pathway
cnl04625  C-type lectin receptor signaling pathway
cnl04650  Natural killer cell mediated cytotoxicity
cnl04657  IL-17 signaling pathway
cnl04658  Th1 and Th2 cell differentiation
cnl04659  Th17 cell differentiation
cnl04660  T cell receptor signaling pathway
cnl04662  B cell receptor signaling pathway
cnl04664  Fc epsilon RI signaling pathway
cnl04666  Fc gamma R-mediated phagocytosis
cnl04668  TNF signaling pathway
cnl04713  Circadian entrainment
cnl04720  Long-term potentiation
cnl04722  Neurotrophin signaling pathway
cnl04723  Retrograde endocannabinoid signaling
cnl04724  Glutamatergic synapse
cnl04725  Cholinergic synapse
cnl04726  Serotonergic synapse
cnl04730  Long-term depression
cnl04810  Regulation of actin cytoskeleton
cnl04910  Insulin signaling pathway
cnl04912  GnRH signaling pathway
cnl04914  Progesterone-mediated oocyte maturation
cnl04915  Estrogen signaling pathway
cnl04916  Melanogenesis
cnl04917  Prolactin signaling pathway
cnl04919  Thyroid hormone signaling pathway
cnl04921  Oxytocin signaling pathway
cnl04926  Relaxin signaling pathway
cnl04928  Parathyroid hormone synthesis, secretion and action
cnl04929  GnRH secretion
cnl04930  Type II diabetes mellitus
cnl04933  AGE-RAGE signaling pathway in diabetic complications
cnl04934  Cushing syndrome
cnl04935  Growth hormone synthesis, secretion and action
cnl04960  Aldosterone-regulated sodium reabsorption
cnl05010  Alzheimer disease
cnl05020  Prion disease
cnl05022  Pathways of neurodegeneration - multiple diseases
cnl05034  Alcoholism
cnl05132  Salmonella infection
cnl05133  Pertussis
cnl05135  Yersinia infection
cnl05140  Leishmaniasis
cnl05142  Chagas disease
cnl05145  Toxoplasmosis
cnl05152  Tuberculosis
cnl05160  Hepatitis C
cnl05161  Hepatitis B
cnl05163  Human cytomegalovirus infection
cnl05164  Influenza A
cnl05165  Human papillomavirus infection
cnl05166  Human T-cell leukemia virus 1 infection
cnl05167  Kaposi sarcoma-associated herpesvirus infection
cnl05170  Human immunodeficiency virus 1 infection
cnl05171  Coronavirus disease - COVID-19
cnl05200  Pathways in cancer
cnl05203  Viral carcinogenesis
cnl05205  Proteoglycans in cancer
cnl05206  MicroRNAs in cancer
cnl05207  Chemical carcinogenesis - receptor activation
cnl05208  Chemical carcinogenesis - reactive oxygen species
cnl05210  Colorectal cancer
cnl05211  Renal cell carcinoma
cnl05212  Pancreatic cancer
cnl05213  Endometrial cancer
cnl05214  Glioma
cnl05215  Prostate cancer
cnl05216  Thyroid cancer
cnl05218  Melanoma
cnl05219  Bladder cancer
cnl05220  Chronic myeloid leukemia
cnl05221  Acute myeloid leukemia
cnl05223  Non-small cell lung cancer
cnl05224  Breast cancer
cnl05225  Hepatocellular carcinoma
cnl05226  Gastric cancer
cnl05230  Central carbon metabolism in cancer
cnl05231  Choline metabolism in cancer
cnl05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
cnl05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cnl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    130879475 (Mapk3)
   04012 ErbB signaling pathway
    130879475 (Mapk3)
   04014 Ras signaling pathway
    130879475 (Mapk3)
   04015 Rap1 signaling pathway
    130879475 (Mapk3)
   04350 TGF-beta signaling pathway
    130879475 (Mapk3)
   04370 VEGF signaling pathway
    130879475 (Mapk3)
   04371 Apelin signaling pathway
    130879475 (Mapk3)
   04668 TNF signaling pathway
    130879475 (Mapk3)
   04066 HIF-1 signaling pathway
    130879475 (Mapk3)
   04068 FoxO signaling pathway
    130879475 (Mapk3)
   04072 Phospholipase D signaling pathway
    130879475 (Mapk3)
   04071 Sphingolipid signaling pathway
    130879475 (Mapk3)
   04024 cAMP signaling pathway
    130879475 (Mapk3)
   04022 cGMP-PKG signaling pathway
    130879475 (Mapk3)
   04151 PI3K-Akt signaling pathway
    130879475 (Mapk3)
   04150 mTOR signaling pathway
    130879475 (Mapk3)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    130879475 (Mapk3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    130879475 (Mapk3)
   04148 Efferocytosis
    130879475 (Mapk3)
  09143 Cell growth and death
   04114 Oocyte meiosis
    130879475 (Mapk3)
   04210 Apoptosis
    130879475 (Mapk3)
   04218 Cellular senescence
    130879475 (Mapk3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    130879475 (Mapk3)
   04520 Adherens junction
    130879475 (Mapk3)
   04540 Gap junction
    130879475 (Mapk3)
   04550 Signaling pathways regulating pluripotency of stem cells
    130879475 (Mapk3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    130879475 (Mapk3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    130879475 (Mapk3)
   04613 Neutrophil extracellular trap formation
    130879475 (Mapk3)
   04620 Toll-like receptor signaling pathway
    130879475 (Mapk3)
   04621 NOD-like receptor signaling pathway
    130879475 (Mapk3)
   04625 C-type lectin receptor signaling pathway
    130879475 (Mapk3)
   04650 Natural killer cell mediated cytotoxicity
    130879475 (Mapk3)
   04660 T cell receptor signaling pathway
    130879475 (Mapk3)
   04658 Th1 and Th2 cell differentiation
    130879475 (Mapk3)
   04659 Th17 cell differentiation
    130879475 (Mapk3)
   04657 IL-17 signaling pathway
    130879475 (Mapk3)
   04662 B cell receptor signaling pathway
    130879475 (Mapk3)
   04664 Fc epsilon RI signaling pathway
    130879475 (Mapk3)
   04666 Fc gamma R-mediated phagocytosis
    130879475 (Mapk3)
   04062 Chemokine signaling pathway
    130879475 (Mapk3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    130879475 (Mapk3)
   04929 GnRH secretion
    130879475 (Mapk3)
   04912 GnRH signaling pathway
    130879475 (Mapk3)
   04915 Estrogen signaling pathway
    130879475 (Mapk3)
   04914 Progesterone-mediated oocyte maturation
    130879475 (Mapk3)
   04917 Prolactin signaling pathway
    130879475 (Mapk3)
   04921 Oxytocin signaling pathway
    130879475 (Mapk3)
   04926 Relaxin signaling pathway
    130879475 (Mapk3)
   04935 Growth hormone synthesis, secretion and action
    130879475 (Mapk3)
   04919 Thyroid hormone signaling pathway
    130879475 (Mapk3)
   04928 Parathyroid hormone synthesis, secretion and action
    130879475 (Mapk3)
   04916 Melanogenesis
    130879475 (Mapk3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    130879475 (Mapk3)
   04270 Vascular smooth muscle contraction
    130879475 (Mapk3)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    130879475 (Mapk3)
  09156 Nervous system
   04724 Glutamatergic synapse
    130879475 (Mapk3)
   04725 Cholinergic synapse
    130879475 (Mapk3)
   04726 Serotonergic synapse
    130879475 (Mapk3)
   04720 Long-term potentiation
    130879475 (Mapk3)
   04730 Long-term depression
    130879475 (Mapk3)
   04723 Retrograde endocannabinoid signaling
    130879475 (Mapk3)
   04722 Neurotrophin signaling pathway
    130879475 (Mapk3)
  09158 Development and regeneration
   04360 Axon guidance
    130879475 (Mapk3)
   04380 Osteoclast differentiation
    130879475 (Mapk3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    130879475 (Mapk3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    130879475 (Mapk3)
   05206 MicroRNAs in cancer
    130879475 (Mapk3)
   05205 Proteoglycans in cancer
    130879475 (Mapk3)
   05207 Chemical carcinogenesis - receptor activation
    130879475 (Mapk3)
   05208 Chemical carcinogenesis - reactive oxygen species
    130879475 (Mapk3)
   05203 Viral carcinogenesis
    130879475 (Mapk3)
   05230 Central carbon metabolism in cancer
    130879475 (Mapk3)
   05231 Choline metabolism in cancer
    130879475 (Mapk3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    130879475 (Mapk3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    130879475 (Mapk3)
   05212 Pancreatic cancer
    130879475 (Mapk3)
   05225 Hepatocellular carcinoma
    130879475 (Mapk3)
   05226 Gastric cancer
    130879475 (Mapk3)
   05214 Glioma
    130879475 (Mapk3)
   05216 Thyroid cancer
    130879475 (Mapk3)
   05221 Acute myeloid leukemia
    130879475 (Mapk3)
   05220 Chronic myeloid leukemia
    130879475 (Mapk3)
   05218 Melanoma
    130879475 (Mapk3)
   05211 Renal cell carcinoma
    130879475 (Mapk3)
   05219 Bladder cancer
    130879475 (Mapk3)
   05215 Prostate cancer
    130879475 (Mapk3)
   05213 Endometrial cancer
    130879475 (Mapk3)
   05224 Breast cancer
    130879475 (Mapk3)
   05223 Non-small cell lung cancer
    130879475 (Mapk3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    130879475 (Mapk3)
   05170 Human immunodeficiency virus 1 infection
    130879475 (Mapk3)
   05161 Hepatitis B
    130879475 (Mapk3)
   05160 Hepatitis C
    130879475 (Mapk3)
   05171 Coronavirus disease - COVID-19
    130879475 (Mapk3)
   05164 Influenza A
    130879475 (Mapk3)
   05163 Human cytomegalovirus infection
    130879475 (Mapk3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    130879475 (Mapk3)
   05165 Human papillomavirus infection
    130879475 (Mapk3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    130879475 (Mapk3)
   05135 Yersinia infection
    130879475 (Mapk3)
   05133 Pertussis
    130879475 (Mapk3)
   05152 Tuberculosis
    130879475 (Mapk3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    130879475 (Mapk3)
   05140 Leishmaniasis
    130879475 (Mapk3)
   05142 Chagas disease
    130879475 (Mapk3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    130879475 (Mapk3)
   05020 Prion disease
    130879475 (Mapk3)
   05022 Pathways of neurodegeneration - multiple diseases
    130879475 (Mapk3)
  09165 Substance dependence
   05034 Alcoholism
    130879475 (Mapk3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    130879475 (Mapk3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    130879475 (Mapk3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    130879475 (Mapk3)
   04934 Cushing syndrome
    130879475 (Mapk3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    130879475 (Mapk3)
   01524 Platinum drug resistance
    130879475 (Mapk3)
   01522 Endocrine resistance
    130879475 (Mapk3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cnl01001]
    130879475 (Mapk3)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:cnl03036]
    130879475 (Mapk3)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cnl04147]
    130879475 (Mapk3)
Enzymes [BR:cnl01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     130879475 (Mapk3)
Protein kinases [BR:cnl01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   130879475 (Mapk3)
Chromosome and associated proteins [BR:cnl03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Protein kinases
     130879475 (Mapk3)
Exosome [BR:cnl04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   130879475 (Mapk3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Haspin_kinase FTA2 Kdo
Other DBs
NCBI-GeneID: 130879475
NCBI-ProteinID: XP_057634036
LinkDB
Position
8:complement(70075523..70081859)
AA seq 379 aa
MAAAAAPGGGGGEPRGAAGVGPGVPGEVEVVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY
DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAPTLEAMRDVYI
VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD
SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFDMELDDLPKERL
KELIFQETARFQPGASEAP
NT seq 1140 nt   +upstreamnt  +downstreamnt
atggcggcggcggcggctccggggggcgggggcggggagccccggggagccgctggggtc
ggcccgggggtcccgggggaggtggaggtggtgaagggacagccattcgacgtgggccca
cgctacacgcagctgcagtatatcggcgagggcgcgtacggcatggtcagctctgcttat
gaccacgtgcgcaagactcgagtggccatcaagaagatcagccccttcgagcaccagacc
tactgccagcgtacactgagggagatccagatcttgctgcgattccgccatgagaatgtc
ataggcatcagagacatcctcagagcacccaccctggaagctatgagggatgtctacatt
gttcaggacctcatggagacagacctgtacaagctgctaaagagccagcagctgagcaat
gaccacatctgctacttcctctaccagatccttcggggcctcaagtatatccactcagct
aacgtgctccaccgggatctgaagccctccaacctgcttatcaacaccacctgcgacctt
aagatctgtgattttggcctggcccggatcgctgaccctgaacatgaccacacaggcttc
ctgacggagtatgtggccacacgctggtaccgagccccagagatcatgcttaactccaag
ggctacaccaaatccattgacatctggtctgtgggctgcattctggctgagatgctctcc
aaccggcccatcttccctggcaagcactacctggaccagctcaaccacattctaggtatc
ttgggctccccatcccaggaggaccttaattgtatcatcaacatgaaggcccgaaactat
ctacaatctctgccctcgaaaactaaggtggcttgggccaagcttttccccaaatctgac
tccaaagcacttgacctgctggaccggatgttaaccttcaaccccaacaagcgcatcact
gtagaggaagcgctggctcacccgtacctggaacagtactatgacccaacagatgagcca
gtggctgaggagcccttcacctttgacatggagctggatgatctccccaaggagcggctg
aaggaactgatcttccaagagacagcccgcttccagccaggggcctcagaggccccctaa

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