Corynebacterium sp. ATCC 6931: DR71_1714
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Entry
DR71_1714 CDS
T03283
Symbol
folC
Name
(GenBank) bifunctional FolC family protein
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
coa
Corynebacterium sp. ATCC 6931
Pathway
coa00790
Folate biosynthesis
coa01100
Metabolic pathways
coa01240
Biosynthesis of cofactors
Module
coa_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
coa00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
DR71_1714 (folC)
Enzymes [BR:
coa01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
DR71_1714 (folC)
6.3.2.17 tetrahydrofolate synthase
DR71_1714 (folC)
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Gene cluster
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
AIN81877
UniProt:
A0A088QEM4
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Position
1928118..1929611
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AA seq
497 aa
AA seq
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MRLSEVSVSEEGLSLPVDVDRPVNEPAPLEATAEELRALAEVEAELDQRWPETKIDPSLE
RIEMLMDILGHPERATPVIHVAGTNGKTSTVRMIESLVRALGRRTGRTTSPHLQLVTERI
AIDGQPIHPRDYVRIWREIQPYVEMVDAKSAEKGGPQMSKFEVLTAMAYAAFADAPVDVA
VVEVGMGGTWDATNVVEADVAVICPIGLDHTEYLGDTLAEIAAEKAGIIKSRWNKDDLLT
PPDNVAIVGEQEPEAMDVVLRRAVEMDASVARAGVEYGVVSHQLAVGGQNLTLKGLAGEY
DDIHLPLHGPHQARNAATALAAVEAFFGAGPGRPLNIDAVREGFATVASPGRLERVRSTP
TVFIDAAHNPHGARALRTALSAEFDFRRVIGVLSVLGEKDARGLLVELEPYFEEVVITQN
TSPRALHYDDLADLAEEIFGEERVHRVPTLPSAVELAVALAEETDTGDGIVSGSGVIVTG
SVVTAGEARTLFGKDPQ
NT seq
1494 nt
NT seq
+upstream
nt +downstream
nt
atgcgcctcagtgaggtctctgtgtccgaggaaggcctgagcctgccggtcgatgtggac
cgcccagtcaacgagccggctccgctggaggccaccgccgaggagctgcgcgcgctcgca
gaggtggaagccgagctggatcagcgctggccggagaccaagattgacccatcactcgag
cggatcgagatgctgatggacatccttggacatcccgagcgtgccactccggtgattcac
gttgccggcactaatggcaagacttccactgttcgcatgattgagtcgctggtgcgagct
ctcggtcggcgcactggtcgcaccaccagtccgcatctgcagctggttaccgagcgcatc
gccattgatggccagcccatccatccacgcgactacgtgcgcatctggcgcgagattcag
ccctacgtggaaatggttgacgccaagtccgccgaaaagggcggcccgcagatgagcaag
ttcgaggtcctcacggccatggcctacgctgccttcgccgacgctcctgtcgatgtcgcc
gtggtggaagtcggcatgggcggcacatgggatgcgaccaacgtggtggaggccgacgtg
gcagtcatctgcccgatcggtctcgatcacacggagtacctcggcgataccctggctgaa
atcgctgctgagaaggccggcatcatcaagtcgcggtggaacaaggacgacctgctcaca
ccaccggacaatgtcgccattgttggcgagcaggaaccggaagcaatggacgtcgttttg
cgccgtgccgtggaaatggatgcctcggtcgcccgcgctggggttgagtatggcgtcgtc
agccatcagctggcggtcggcgggcagaacctaacgctcaagggcctggccggcgagtat
gacgacatccatctgccactgcacggtccgcatcaggcgcgcaacgccgccacagcgctg
gccgcggtggaggcgttcttcggcgcaggtccgggacgtccgctcaacattgatgcggtt
cgcgaaggctttgcgacggtcgcatcgcccggccgcctggagcgcgtgcgttcgaccccg
acggtgtttatcgatgccgcccacaatcctcacggtgcccgtgcgctacgcacggcgctc
tccgctgagttcgacttccgccgtgtcattggtgtgctgtcggtgttgggggagaaggat
gctcgtgggctgctggtggagctggagccgtacttcgaagaagtggtaatcacccagaac
acctcgccgcgtgcgctgcactacgacgacctggctgaccttgcggaggagattttcggc
gaggagcgcgtgcatcgcgtgccaactctgccgtccgccgttgagctagctgtcgcgctg
gctgaagaaaccgacaccggtgacggtattgtctctggttccggtgtgatcgtcactgga
tcggttgttaccgcgggcgaggcccggacactatttggaaaggacccgcaatga
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