Cobetia sp. AM6: CLAM6_07260
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Entry
CLAM6_07260 CDS
T08724
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
cobe
Cobetia sp. AM6
Pathway
cobe00300
Lysine biosynthesis
cobe00550
Peptidoglycan biosynthesis
cobe01100
Metabolic pathways
cobe01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
cobe00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CLAM6_07260 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CLAM6_07260 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CLAM6_07260 (murF)
Enzymes [BR:
cobe01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CLAM6_07260 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BBO55415
UniProt:
A0A5K7YC77
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All DBs
Position
872509..873972
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AA seq
487 aa
AA seq
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MSAPEQPVALDTFEEVAAVLGAQLPQALRGQVLGAIETDTRKLGEQAAPLFVALKGERFD
AHDFLAQARANGAVAALVERAVDDPLPQIVVADTRLAFGLLAAARRRAWGRPLIAVTGNS
GKTSVKGLVHAILVRDAARFEAESLANHGNLNNDFGLPMTLLRLSNAHQHGVVELGANHL
GEIAWTTALARPQVAVITNVTGAHVGEFGGMGQIAQAKGEILAGLSPLGGRRPVAVLNRD
DAYFSLWQALAATGQAVDVIDFSVADGVVDSSVDSVDRPARLQARELGADELGRYAFALT
FDGRSLGRVQLALLGRHNVANALAAAAACLALGIDSDLVIAGLESAESVPGRLGVVAGIN
GSRLLDDSYNANPGAMLAALDLLATLPAPRWFLMGAMGELGADAERLHAEVGDHARKLGI
DFIATCGEGAQATAEAFGAGGKHFIERAELEAYARNHLPTGASVLVKGSRSAGMENVVAA
LKVDASR
NT seq
1464 nt
NT seq
+upstream
nt +downstream
nt
atgagtgcgcctgaacagcccgtcgctctggacaccttcgaggaagtagccgcggtgctc
ggggcgcagttgccacaggcattgcgtggtcaggtgctgggcgccatcgagacggacacc
cgcaagcttggcgagcaggccgcaccgctgttcgtggccctgaagggtgagcgcttcgac
gcccatgacttcctcgcccaggctcgcgccaatggcgccgtcgcggcgctggtcgagcgg
gcagtggatgatccgctgccgcagatcgtcgtcgcggatacccgcctggccttcgggctg
ctggcggcagcgcgtcgccgtgcctgggggaggccgctgatcgcggtgaccggcaacagt
ggcaagaccagcgtcaagggcctggtgcatgccatccttgtgcgggatgccgcgcgtttc
gaggccgaaagcctcgccaatcacggcaacctcaacaacgatttcggcctgccgatgacg
ttgctgcgcttgagcaacgcccaccagcacggtgtggtcgaactgggcgccaatcatctc
ggcgagatcgcctggacgacggccctggcgcgcccgcaagtggcggtgatcaccaatgtc
accggcgcccatgtcggcgaattcggcggcatggggcagatcgcccaagccaagggcgag
attctggcgggcttgagcccgttgggagggcgacgtccggtcgcggtgctcaaccgtgat
gacgcctacttctcgctatggcaggcgctggccgcaaccggccaggcggtcgatgtcatc
gacttcagcgttgcggatggcgttgtggatagcagcgtggatagcgttgatcgcccggca
cgcctgcaggcgcgtgagctaggcgcggatgaactcgggcgttatgctttcgcactgacg
tttgatggccgctcgctcggtcgtgtccagctggcgttgctggggcgtcacaacgtggcc
aatgcgctggcggctgccgcggcgtgcctggcactgggcatcgacagtgatctggtgatc
gccgggctcgagagcgccgagagcgtgcccggcaggctgggtgtcgtggcgggcatcaac
ggttcgcgtctgctggatgacagctacaacgccaaccccggcgccatgctggcggcgctg
gatctgctggcgacactgcctgcgccgcgctggttcctgatgggcgccatgggcgaactc
ggagccgacgccgagcgtctgcatgccgaggtgggcgatcacgcccgcaagctgggcata
gatttcattgccacctgcggcgagggcgctcaggcgactgccgaggccttcggggccggt
ggcaagcactttatcgagcgggcagagctggaagcttacgcccgtaaccatctacccacc
ggggccagtgttctggtcaaggggtctcgcagcgctggcatggagaatgtcgttgccgcg
ctcaaggtcgacgcatcaaggtga
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