Comamonas flocculans: FOZ74_11465
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Entry
FOZ74_11465 CDS
T06146
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
cof
Comamonas flocculans
Pathway
cof00230
Purine metabolism
cof01100
Metabolic pathways
cof01110
Biosynthesis of secondary metabolites
Module
cof_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
cof00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
FOZ74_11465 (purL)
Enzymes [BR:
cof01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
FOZ74_11465 (purL)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
QEA13601
UniProt:
A0A5B8RVQ1
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Position
2398179..2402270
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AA seq
1363 aa
AA seq
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MSLHLTLFAGGNAIGSFRAQRLLASLQAVHPRVVGVQARHLHLVATPGPLDAAMRDRLAA
LLDYGEPLGAADEGEALIVTPRLGTISPWASKATDIARNCGLAVQRIERVTEYRFALKGG
LLGGKAELTLAQRDQIAALLHDRMTESVVATRGEAERLFTELQAEPMASVDVLARGRAAL
ETANTAWGLALADDEIDYLVAAFTQLGRNPTDVELMMFAQANSEHCRHKIFNAQFTIDGV
AQAHTLFGMIRHTEATSPQHTIVAYADNASVMEGAEVEEFMAKSASNAGEAGAGSYQKQK
MLRHVLMKVETHNHPTAISPFPGASTGAGGEIRDEGATGRGSRPKAGLTGFTVSRLWGSA
LGKPEHIASPLQIMTEGPLGGAAFNNEFGRPNLAGYFREYEQLVDGVQRGYHKPIMLAGG
LGSIDARLTKKIPFPAGTLLVQLGGPGMRIGMGGGAASSMASGANAAALDFDSVQRGNPE
IERRAQEVINQCAALGEANPILAIHDVGAGGLSNAFPELVNDAGRGARFDLRAVPLEESG
LSPREIWSNESQERYVLAIAPESLAQFQALCERERCPFAVVGVATEARQLVVGDLDLPLP
PLGEGREGGQHDDGATHQPPPQPSPSGGGSAMAVDMPMDVLLGKPPKMQRDVTRVARQGT
ELPLDDLAVEKAVIEVLAHPTVASKRFLVTIGDRSVGGLTHRDQMVGPWQLPVADVAVTL
ADYSGFSGEAMAVGERTPIASLNAPASGRMAVAEAITNLLAAPIELERVKLSANWMAACG
EPGEDAALYDTVRAVGLELCPQLGISIPVGKDSLSMRTQWSDGGTPKKVVSPVSLIVSAF
ATLDDVRGTLTPQLDASVEDSSIVLIDLGHGKMRMGGSILGEVLGASGTEAPDLDDPEDL
KRLVAAINALRQRGLVLAYHDRSDGGLIATVAEMAFAGQVGVALNVDMLVSEGDGIRDGR
MDSFEAKEWTKQISGRRDVLTLRALFNEELGAVLQIATAERSAVMQVLREHGLIQCSHLI
GKTRPEASPMKAGKGELQVWRDAKKVFGAPLVDLHQVWDAVSWKIAQGRDNPACADAEHA
AAGDPANPGLHQHVTFDAQEDVAAPFLNLARPRVAVLREQGVNSHVEMAYAFGVAGFDPV
DVHMSDLQAGRVSLRDMQGIVACGGFSYGDTLGAGVGWARSITFNARLAEQFQQFFGRTD
TFALGVCNGCQMFAELSPIIPGAKAWPRFTTNQSHRFEARLSMVEVLESPSIFFTGMAGS
RLPIAVSHGEGYANFGVRGDAASVVRALRFVDNHGQVSDAYPANPNGSPEGLTAVTTADG
RFTAMMPHPERVFRNLQMSWTPGDPAAFSPWMRLWRNARRWVG
NT seq
4092 nt
NT seq
+upstream
nt +downstream
nt
gtgtccttgcatctcaccctgtttgccggcggcaacgccatcggatcgtttcgcgcgcag
cggctgctcgccagcctgcaggccgtgcaccccagggtggtcggcgtgcaggcccgccat
ctgcatctggtggccacgcccgggccgctggacgcggccatgcgcgatcgcctggccgcg
ctgctggactacggagaacccttgggagccgccgacgagggcgaggcgctgatcgtcacg
ccgcgcctgggcacgatctcgccctgggcctccaaggccaccgacatcgcgcgcaactgt
ggacttgcggtgcagcgcatcgagcgggtgaccgagtaccgcttcgcgctcaagggcggc
ctgctgggcggcaaggccgaactcacgctcgcgcagcgcgaccagattgccgcgctcttg
cacgaccgcatgaccgagtcggtcgtcgccacgcggggcgaggccgagcggctcttcacc
gaactgcaggccgagcccatggcgagcgtggacgtgctcgcccggggccgcgccgcgctg
gagacggccaacaccgcctggggcctggcgctggccgatgacgagatcgactacctggtg
gcggccttcacccagctcgggcgcaaccccacggacgtggagctgatgatgttcgcccag
gccaacagcgagcattgccgccacaagatcttcaatgcgcaattcaccatcgacggcgtg
gcgcaggcgcacacgctgttcggcatgatccgccacaccgaggccacctcgccgcagcac
accatcgtcgcctatgccgacaacgcctccgtgatggagggcgccgaggtagaagaattc
atggccaaatcggcctcaaacgcaggcgaggcgggcgccggcagctatcaaaaacaaaag
atgctgcgccacgtgctgatgaaggtggaaacacacaaccaccccacggcgatctccccc
ttccccggcgcctccaccggcgcgggcggcgagatccgcgacgaaggcgccaccggccgc
ggctcgcgccccaaggcggggctgacgggcttcacggtctccagactctggggcagcgcg
ctgggcaagcccgagcacatcgccagcccactgcagatcatgaccgaaggcccgctgggc
ggcgcggccttcaacaacgagttcggccgccccaatctggcgggctacttccgtgaatac
gaacaactggtcgatggcgtgcagcgcggctaccacaagcccatcatgctggccggtggc
ctgggcagcatcgacgcgcgcctgacgaagaaaatccccttccccgccggcacgctgctg
gtgcaattgggcggccccggcatgcgcatcggcatgggcggcggtgcggccagctccatg
gccagcggcgccaacgcggccgcgctggacttcgactccgtgcagcgcggcaaccccgag
atcgagcgccgcgcgcaagaagtcatcaaccagtgcgcggccctgggcgaggccaatccc
atcctggcgatccatgacgtgggcgcgggcggcctgtccaacgccttccctgaactggtc
aacgacgccgggcgcggtgcgcgttttgacctgcgcgccgtgccgctggaagaaagcggc
ctttcgcccagggaaatctggagcaacgagagccaggagcgctacgtgctggccatcgcg
cccgagtcgctggcgcagtttcaggccctttgcgaacgcgagcgctgcccgttcgccgtc
gtcggtgtggccaccgaagcgcgccagctcgtcgtcggcgacctggatctgccccttccc
ccgctgggggaaggccgggaggggggccagcatgatgacggggcaacgcaccagccccca
ccccagccctcccccagcgggggagggagcgcgatggccgtggacatgccgatggacgtg
ctgctgggcaaaccgcccaaaatgcagcgcgacgtgacccgcgtcgctcgccagggcacg
gaactgccgctggacgacctggccgtggaaaaggccgtcatcgaggtgctcgcccatccc
acggtcgccagcaagcgttttctcgtcaccatcggcgaccgcagcgtcggcggcctcacc
caccgcgaccagatggtcggcccctggcagcttcccgtcgctgacgtcgccgtcacgctg
gccgactacagcggtttttccggtgaagccatggccgtgggcgaacgcacgcccatcgcc
agcctgaacgccccggcctccggacgcatggcggtggctgaagccatcaccaacctgctg
gctgcgcccatcgagctggagcgcgtcaagctcagcgccaactggatggccgcctgtggc
gagccgggcgaagacgccgcgctctacgacactgtgcgcgccgtcggcctggagctgtgc
ccgcagctcggcatctccatcccggtgggcaaggacagcctctcgatgcgcacgcagtgg
agcgacggcggcacgcccaagaaggtcgtctcgcccgtgagcctcatcgtcagcgcgttt
gccacgctggatgatgtgcgcggcacgctcacgccgcagctcgatgccagcgtggaggac
agctccatcgtgctgatcgacctgggccacggcaagatgcgcatgggcggctccatcctc
ggcgaagtgctgggcgcaagcggcaccgaggcgcccgacctggacgaccccgaagacctc
aaacgcctggtggccgccatcaatgcgctgcgccagcggggcctggtcctcgcctaccac
gaccgcagcgacggcggcctgatcgccaccgtggccgagatggcgtttgccggccaggtg
ggcgtggcgctgaacgtggacatgctggtgagcgagggtgacggcatccgggacggccgc
atggacagcttcgaggccaaggaatggaccaagcagatcagcggccggcgcgacgtgctc
acgctgcgtgcgctgttcaacgaagaactcggcgcggtgctgcagatcgccaccgccgag
cgctccgccgtcatgcaggtgctgcgcgagcatggcctcatccagtgcagccacctcatc
ggcaagacccggcccgaagcctcgccgatgaaggcgggcaagggtgaactgcaggtctgg
cgcgacgcgaaaaaggtctttggcgcgccgctcgtcgatctgcaccaggtctgggacgcc
gtgagctggaagatcgcccagggccgcgacaaccccgcctgcgccgacgccgagcacgcc
gccgcgggcgaccccgccaaccccggtctgcaccagcatgtgaccttcgacgcgcaggaa
gacgtcgccgcgcccttcctgaacctggcccggccccgcgtggccgtgctgcgcgagcag
ggcgtgaactcccacgtcgagatggcctatgccttcggcgtggccggttttgaccccgtg
gacgtgcacatgagcgacctgcaggccggccgcgtgagcctgcgggacatgcagggcatc
gtcgcctgcggcggcttcagctacggcgatacgctgggcgcgggcgtgggctgggcgcgc
tccatcaccttcaacgcgcgcctggccgagcaattccagcaattcttcggccgcacggac
accttcgcgctcggcgtgtgcaacggctgccagatgttcgccgaactctcgcccatcatc
cccggcgccaaggcctggccgcgctttaccaccaaccagagccaccgcttcgaggcgcgt
ctgtccatggtggaggtgctcgaatcgcccagcatcttcttcaccggcatggccggcagc
cgcttgccgatcgccgtctcgcacggcgagggctacgccaacttcggcgtgcgcggcgac
gccgccagcgtggtgcgcgcgctgcgcttcgtggacaaccacggccaggtgagcgatgcc
taccccgccaaccccaacggcagccccgagggcctgacggccgtcaccaccgcggacggg
cgcttcaccgccatgatgccccaccccgagcgggtgtttcgcaacctgcagatgagctgg
acgccgggcgacccggccgccttcagcccctggatgcgcctgtggcgcaacgcccgccgc
tgggtgggttga
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