Cohnella sp. LGH: J4772_06700
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Entry
J4772_06700 CDS
T10185
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
cohl Cohnella sp. LGH
Pathway
cohl00790
Folate biosynthesis
cohl01100
Metabolic pathways
cohl01240
Biosynthesis of cofactors
Module
cohl_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
cohl00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
J4772_06700
Enzymes [BR:
cohl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
J4772_06700
6.3.2.17 tetrahydrofolate synthase
J4772_06700
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GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
QTH44086
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Position
complement(1672401..1673786)
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AA seq
461 aa
AA seq
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MTNDKQAEQIAFRTAEEAMAWITGLTAFGIRPGLDRIQALMERFNHPERRLKFIHVAGTN
GKGSVCAYLTSVLLKSGYDVGTFTSPYLTSYSNRLQYNGEDIADEHLVLLANRLKPAAEE
LAGGELGAPTMFEVTTALALLYYGTVSFPDYVVWETGLGGRLDVTNVVTPVVSIITNVGH
DHMDVLGPTLTDISREKAGIIKSGVPVVTSVSQPEVVQVVEETARARKATVYRAGEQFVS
ETLTVAEDEQSFSFRSPFRAIPALTITLSGEHQIANAAAAVMALEVLRQYCALIVDDEHL
EAGLKETKWPGRLEMVSRQPRILIDGAHNPEGMEALSRALKNVYTFDRLNVMMAMMPNKN
HEHSLRHILPLVDTLVITEPDFHKKMNADELAAVAARVAAELDLSPTVIVEPDWRRALEL
LLGASSSAGDANVLNAVTGTLYLIADVRSWLLQGTKSEKGW
NT seq
1386 nt
NT seq
+upstream
nt +downstream
nt
atgactaatgacaaacaagccgaacagattgccttccgcacggccgaggaagcgatggct
tggattaccgggctgaccgctttcggcatccgtccgggccttgaccggatccaggcgttg
atggaacgattcaaccatccggagcgaaggctgaagttcatccatgtggcgggcacgaac
ggcaaaggctcggtatgcgcctatctgacgagcgtgctgctgaaaagcggatacgacgtg
gggacgtttacgtccccgtatctcacctcttattccaaccgtctgcaatacaacggagaa
gacatcgccgatgagcatctcgtattgctcgccaatcggctgaagccagcggcggaggaa
ctggctgggggcgagctaggcgcgcctacgatgttcgaggtaacgacggcgctggcactg
ctctattacggaacggtttcgttccctgattacgtcgtgtgggagaccggacttggcggc
cgtttggatgtgaccaacgtcgtcaccccggtggtcagcattattaccaacgtcggccac
gaccatatggacgtgcttggaccgacgctgaccgatatctcccgcgagaaggccggcatt
atcaagtcgggcgtgcccgtcgttacatcggtctcccagccggaggtcgtgcaggtcgtc
gaagagacggcgcgcgcgcgcaaagcgaccgtataccgggcgggagagcagttcgtcagc
gaaacgttgaccgtggcggaagatgaacagagcttttctttccgcagcccattccgggct
attcctgctttgacgattacgctaagcggagagcatcagatcgcgaacgcggcggcggcg
gtcatggcgcttgaagtgctgcgtcagtattgcgcgctgatcgtcgacgacgagcatttg
gaagccggtttgaaggagaccaaatggcccggaaggctggagatggtatcccgccagccg
cgaattctaatcgacggagcgcacaatccggaggggatggaggcgcttagccgcgctctg
aagaacgtatatacgttcgatcgcctgaatgtaatgatggcgatgatgccgaataagaat
catgagcattcattgcggcatatactaccattggtggatacgcttgtgattacggaaccg
gattttcataaaaaaatgaatgccgacgagctcgccgctgtcgcggcgcgggtggccgca
gagctggatctgtcgcctaccgtgatcgtggagccggattggcggcgcgcgctggagttg
ctgctcggggcttcatcttcagccggggatgcgaacgtgctgaacgcggtgaccggtacg
ctgtacctgatcgcggacgtccgttcttggctgcttcaaggcacgaaatctgaaaaaggc
tggtga
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