Cohnella sp. LGH: J4772_11640
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Entry
J4772_11640 CDS
T10185
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
cohl Cohnella sp. LGH
Pathway
cohl00290
Valine, leucine and isoleucine biosynthesis
cohl00660
C5-Branched dibasic acid metabolism
cohl01100
Metabolic pathways
cohl01110
Biosynthesis of secondary metabolites
cohl01210
2-Oxocarboxylic acid metabolism
cohl01230
Biosynthesis of amino acids
Module
cohl_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
Enzymes [BR:
cohl01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
J4772_11640 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
J4772_11640 (leuC)
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NCBI-ProteinID:
QTH44991
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Position
2772414..2773835
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AA seq
473 aa
AA seq
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MSKKTMFEKIWENHEIVAEQGKPSILYIDLHLVHEVTSPQAFEGLRLSGRKVRRPELTFA
TMDHNVPTKDRFNIADPISKQQVDTLTANCKEFGVKLYDLNTIDQGVVHVMGPELGLTHP
GKTIVCGDSHTSTHGAFGALAFGIGTSEVEHVMATQCLQQAKAKTMCIRFNGKRKPGITA
KDMILGLIAKYGTDFGTGYVMEYTGEAIRELSMEERMTVCNMSIEAGARAGLIAPDETTF
EYLRGREYAPQGEAYDKAVEQWKALCTDEGATFDLTLDFDVESLIPQVTWGTSPGMGTGI
TDSVPVPEELPTENERKAAKSAIEYMGLKPGTPMTDIEIDYVFIGSCTNGRIEDLRAAAS
VARGHKVSSQVTAIVVPGSGRVKLQAEKEGLDKIFTEAGFEWREAGCSMCLAMNPDVLQP
GQRCASTSNRNFEGRQGRGGRTHLVSPEMAAAAAIQGRFVDVRKWDFKAEVTA
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
atgagcaaaaagacgatgttcgagaaaatttgggaaaaccacgagatcgtagccgaacaa
gggaagcctagcattctctatatcgatctccatctggtgcacgaggttacgtccccgcaa
gcgttcgagggactgcgcctgtccggccgcaaggtgagacgtccggaattgacgttcgcg
acgatggaccacaacgttccgaccaaagaccgcttcaacattgccgatccgatctccaag
cagcaggtcgacacgctgacggcaaactgtaaagagttcggcgtcaagctgtacgacctg
aacacgatcgaccaaggcgtcgttcacgttatgggacctgagctgggcttgacccatccg
ggcaaaacgatcgtctgcggcgacagccacacatcgactcacggcgcattcggcgctctc
gcgttcggtatcggaacgagcgaagtcgaacacgttatggcgacgcaatgcttgcagcaa
gccaaagcgaaaacgatgtgcattcgcttcaacggcaagcgcaagccgggcattaccgct
aaagacatgattctcggtctgatcgccaaatacggcacggacttcggtacgggctacgtt
atggaatatacgggcgaagcgattcgcgagctgtcgatggaagagcggatgaccgtctgc
aacatgtccatcgaagccggcgctcgcgccggtctgatcgctccggacgaaacgactttc
gaatacttgcgcggccgcgagtacgctccgcaaggcgaagcatacgataaagcggttgaa
cagtggaaagcgctgtgcacggatgaaggcgcaacgttcgatttgactctcgatttcgac
gtagagtcgttgattccgcaagtgacttggggcacgagccctggcatgggtacgggcatt
accgattccgtgccggttccggaggaactgccgaccgagaacgagcgcaaagccgctaag
agcgcgatcgagtacatgggactgaagccgggcacgccgatgaccgatatcgagatcgac
tatgtatttatcggttcttgcacgaacggacggatcgaagacttgcgagctgcggcatcc
gtagcgcgtggtcacaaagtcagctctcaagtaactgcgatcgtcgttccgggctcggga
cgcgtcaagctgcaagccgagaaggaaggcttggataaaatctttaccgaagccggtttc
gaatggcgcgaagcaggctgcagcatgtgcctcgcgatgaaccccgacgtgcttcaaccg
ggacagcgctgcgcatcgacgtccaaccgcaacttcgaaggccgtcaaggccgcggcggg
cgcacgcacctcgtatcgccggagatggcggctgcggctgcgatccaaggccgtttcgtc
gacgtgcgcaagtgggatttcaaagccgaagtgacggcgtaa
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