Cohnella sp. LGH: J4772_17720
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Entry
J4772_17720 CDS
T10185
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
cohl Cohnella sp. LGH
Pathway
cohl00300
Lysine biosynthesis
cohl00550
Peptidoglycan biosynthesis
cohl01100
Metabolic pathways
cohl01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
cohl00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
J4772_17720
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
J4772_17720
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
J4772_17720
Enzymes [BR:
cohl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
J4772_17720
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF2525
Motif
Other DBs
NCBI-ProteinID:
QTH46101
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Position
complement(4107763..4109178)
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AA seq
471 aa
AA seq
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MMQATVRQTADWVGALEIVGDTAVGEEQLLSGVSTDTRSIRPGQLFVPLRGERFDGHDYI
ITASEAGAAAALWDAAVPQPEGLDLPLILVPDTLEALQRLASAYLSERLTAAKVVAITGS
NGKTTTKDLIASVLATSFLVHKTEGNYNNHIGLPLTILSAPANTEALVLEMGMSGFGEIS
LLTRLASPDIAVITNIGESHLLQLGSRRGIAQAKLEIAEGLKPGGALVYCGDEPLLAEAL
AERPVTEGKKLITFGENAGSDWVARYVRVTAEGTRFTATGELETAFELPIPGRHNAVNAL
AAVAVGRLLGLSAEAIGEGLKMTKLTGMRIERSAAWNGAVILNDAYNASPTSVRAAIDLV
AELSGYRRKWVVLGDMLELGDGELELHGDIGRYLDRAKVDRALLYGPRSKQIYEEARTKF
EDQDVLYFDDKKALGECLLTALSPDDLVLVKASRGMKMEEIVTTLQRGGGQ
NT seq
1416 nt
NT seq
+upstream
nt +downstream
nt
gtgatgcaggcaacagttcggcaaacggccgattgggtcggcgcgttggagattgtcggc
gatacggccgttggcgaggagcagctcctgtccggcgtatcgaccgatacgcgcagcatt
cgtccggggcagttgttcgttcctttgaggggagaacggttcgacggacatgattatatc
attacggcaagcgaggcgggggcggcagccgcgctgtgggacgctgcggttccgcagccg
gaaggcttggatcttccgctcattctcgtgccggacacgctggaggcgctgcagcggctg
gcttcggcttatttaagcgagcggcttactgccgcgaaagtggtggcgatcaccggcagc
aacggcaagacaacgaccaaggacctgattgcgtccgtattggcgacatcgtttcttgta
cataaaaccgaaggcaattacaataatcatatcgggcttccgcttacgattctaagtgcg
ccggcgaataccgaagcgcttgtactggagatggggatgagcggctttggggaaatttcg
ctgctcacccggttagccagtccggacatcgcggtgattacgaatatcggcgagtcgcat
ttacttcagctcggctcgcggcgagggatcgcccaggcgaagctggaaatcgccgaaggg
ctgaagccgggcggcgcgcttgtttattgcggcgacgagccgctgcttgcggaagcgctg
gcggagcggcctgtaaccgaagggaagaagctgattacgttcggcgagaacgccggcagc
gattgggtcgcgcgctacgtacgcgtgacggcggagggaacgcggtttacggcgacgggc
gagctggagacggcattcgagctgccgatccccgggcggcataatgcggtaaacgcgctg
gccgcggtagccgtgggccgcttgctgggcctgtccgcggaagcgatcggcgaagggctt
aagatgaccaagctgacggggatgcgcatcgagcggagcgccgcctggaacggggcggtc
attctcaacgacgcctacaacgccagcccgacgtcggtcagggcggcaatcgatctggtg
gcggagctgtccggctatcgccgcaaatgggtcgtgcttggcgatatgctggagctcggc
gacggcgaactggagctgcacggcgacatcgggcgctacctggatcgcgccaaggtggat
cgggcgctgctgtacggaccgcgatccaagcaaatttacgaggaagcgcgcacaaaattt
gaagatcaagacgttctctatttcgacgacaagaaagctcttggcgagtgtctgctcacc
gcgctttctccggacgatttagtgctcgtcaaagcatcgaggggcatgaaaatggaagaa
atcgtaacgacgctgcaaagagggggcggacagtga
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