Corynebacterium pseudotuberculosis CIP 52.97: CPCIP5297_00915
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Entry
CPCIP5297_00915 CDS
T02054
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
coi
Corynebacterium pseudotuberculosis CIP 52.97
Pathway
coi00290
Valine, leucine and isoleucine biosynthesis
coi00620
Pyruvate metabolism
coi01100
Metabolic pathways
coi01110
Biosynthesis of secondary metabolites
coi01210
2-Oxocarboxylic acid metabolism
coi01230
Biosynthesis of amino acids
Module
coi_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
coi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
CPCIP5297_00915 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CPCIP5297_00915 (leuA)
Enzymes [BR:
coi01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
CPCIP5297_00915 (leuA)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
AEQ05732
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Position
complement(176925..178742)
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AA seq
605 aa
AA seq
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MGPTDAFISAPADIHTPSGSFAAGQATWNKQRSSDLPVHRYLPFAAKVEKIDLPDRTWPS
ATIDTAPQWCAVDLRDGNQALIDPMSPERKRRMFNLLVAMGYKEIEVGFPSASQTDFDFV
REIIEKNMVPEDVTIQVLVQAREHLIRRTFEACEGAKNVIVHFYNSTSILQRDVVFRKDK
KAIKKLATDAAELIKSIAAEYPNTNWRWEYSPESFTGTELAYAKEVIDAVVEVMDPTPMR
PIIINLPSTVEMTTPNTYADSIEWMHRHLRRRDSIILSLHPHNDRGTGVAAAELGYLAGA
DRIEGCLFGNGERTGNVCLVTLGLNMLTQGVDPQIDFSDIEQIRRTVEYCNQLRVPERHP
YGGDLVFTAFSGSHQDAVNKGLDAMASRVRPGATHVDVSWEDLRAETWDVPYLPIDPKDV
GRNYEAVIRVNSQSGKGGVAYIMKTDHGIALPRPMQIEFSSVVQRVTDARGGEVDSQHMW
DIFTHEYLNRTAPIQQISMRVDAAQNETDSAHIAATLKFQGKETIVEGRGNGPIAAYANA
LESLGIDVEVQEYEQHARTAGDDAESAAYILAEVNGQRYWGVGIAGSITYASLKAITSAV
NRALS
NT seq
1818 nt
NT seq
+upstream
nt +downstream
nt
atgggccccaccgacgcttttatctccgcaccagccgatatccataccccttctggcagc
ttcgccgccggacaagctacttggaacaaacaacgctcatcggatcttccagtccaccgc
tacctcccctttgctgccaaagtggaaaaaatcgatcttccggatcgcacatggcccagt
gccaccattgataccgccccgcaatggtgcgccgtagatctacgcgatggtaaccaagcg
ctcattgaccccatgagtcccgagcgcaaacgacgcatgtttaacctgttagtggccatg
ggatacaaggagattgaagtagggttcccctcagcctctcaaacagactttgattttgtc
cgcgagatcatcgagaaaaacatggtccccgaggacgtcaccatccaagtcctggttcaa
gcacgagagcatctcatccgtcgcacctttgaggcctgcgagggcgcgaaaaacgttatc
gttcacttttacaactccacatccattctgcagcgtgatgttgtcttcagaaaggataaa
aaggcgataaaaaagctggccaccgatgccgccgaactcatcaaatctattgccgcagag
tatccaaacactaactggcgatgggaatactcgcctgagtccttcactggcaccgagctc
gcttacgcaaaagaagtgatcgatgcagtagtcgaggtcatggatcccacccctatgcgc
cccatcatcatcaatctgccttccacggtggagatgaccactcccaacacatatgcagac
tccatcgaatggatgcaccgacacctacgccgtcgcgattccatcatcctctcactgcac
ccacataacgatcgtggcaccggcgttgccgccgccgaactcggatatttggcgggcgcc
gatcgcatcgagggctgtctctttggcaatggcgagcgcaccggaaatgtctgcttagtc
actcttgggctgaacatgcttacccagggagtagatccgcaaattgacttctccgatatt
gagcagatccgccgaaccgtagaatactgcaatcagctgcgcgtccctgaacgtcacccc
tatggcggcgatctggtatttacggctttctctggctcgcaccaagacgccgttaataaa
ggcctggatgccatggcgtcgcgggttcgtcccggcgcgactcacgttgacgtctcatgg
gaggatctccgggcagaaacctgggacgtcccttacctccccatcgatcccaaggatgtg
ggccgcaattacgaggcagttatccgcgtcaactctcagtctggcaaaggcggcgtagcc
tacattatgaagaccgaccacggcatcgctcttccccgccctatgcagatcgaattctcc
tccgtagtccagcgtgtcactgacgccaggggcggcgaagtagattctcagcacatgtgg
gatatcttcacccatgaatacttgaaccgcactgcgccaatccagcaaatctctatgcgt
gtcgacgccgcccagaatgaaacagactcagcccacattgctgccacgctgaaattccaa
ggcaaggaaactatcgttgagggccgcggcaatggccccatcgccgcctatgccaatgca
ctcgagtccttgggcatcgacgtggaagtgcaggaatacgagcagcatgcccgaaccgcc
ggcgacgatgcagaatctgccgcatatattctggcggaggtaaatgggcagcgctattgg
ggcgtaggtatcgcaggatcaattacttacgcttctctcaaagccattacctcggcagtc
aaccgcgcactgagctaa
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