Colwellia sp. PAMC 21821: A3Q33_05955
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Entry
A3Q33_05955 CDS
T04816
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
colw
Colwellia sp. PAMC 21821
Pathway
colw00300
Lysine biosynthesis
colw00550
Peptidoglycan biosynthesis
colw01100
Metabolic pathways
colw01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
colw00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
A3Q33_05955 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
A3Q33_05955 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
A3Q33_05955 (murF)
Enzymes [BR:
colw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
A3Q33_05955 (murF)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
ARD43895
LinkDB
All DBs
Position
complement(1426105..1427505)
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AA seq
466 aa
AA seq
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MISLTLTELSTAINGQLLGESSTIKAISTDSRALKAGDVFLALQGPNFDGHKFLTQASEL
GCSAVIVQKAQENLNIAQIVVEDTHKALGEIGAYVKAKVAPKTVAITGSSGKTTVKEMVA
AILNRLGNVLATKGNFNNDIGVPLTLLRLEEQHDFAVVELGANHIGEIAYTSALVKPDVA
IINNIAAAHLEGFGDLCGVARAKGEIFSGLNAGGVAIYNQDTQWADKWQWRLTDKKVLRF
SCKDSADFYSHQEVLDSNGCANFTLMTPMGSVEIALTVPGHHNVCNAVAAATIAVEFGAS
LDDIRLGLAEMAEVKGRLNLHQLDSKTKLIDDTYNANVESINAASDLLASYSGRRVLILG
DMGELGEEARRYHQEVGEHAKNKHIDDLLTLGVLSQHASDAFYQGQEAQAQHFSSKEKLL
SRLQQLLQGEEQQVTILVKGSRSAHMEYVVADIIQWHNSQTMQEQA
NT seq
1401 nt
NT seq
+upstream
nt +downstream
nt
atgatctcgttaaccttaactgaattatcaacagctattaatggccaactgttaggtgag
agctcaaccataaaagcgataagcaccgatagtcgtgccttaaaggctggtgatgttttc
ttagcattgcaagggccaaattttgatggtcataaattcttaacgcaagccagtgagctg
ggttgtagcgcggttattgtccaaaaagcacaagaaaacctcaatattgcgcaaatcgtc
gtcgaagatacacataaggcattaggcgaaattggtgcttatgtaaaagccaaagtggcg
cctaaaacggtagcgattaccggtagcagtggtaaaaccacggtaaaagagatggtcgcg
gcgattttaaatcgcttaggcaatgtactcgctaccaaaggtaactttaataacgatatt
ggtgtgccactgacgctattacgattagaagagcagcatgactttgccgtggtggaatta
ggtgctaatcatattggtgaaatcgcttatacctcagcactggttaagcccgatgttgcc
attattaataatatcgccgcagctcacttagaaggttttggtgacttatgtggcgtagca
cgcgcgaaaggtgaaattttttctggcttaaacgctggtggcgttgctatttataatcaa
gacactcagtgggctgacaaatggcaatggcgcttaacagataaaaaagtgctgcgattt
tcatgtaaagacagcgctgatttttacagtcatcaagaagttttagatagcaatggttgt
gcaaattttacattaatgacccctatgggcagtgttgaaattgcactgaccgtgccaggg
catcacaacgtctgcaatgccgttgctgccgcgactatcgcagtagagtttggtgctagt
ttggacgatattcgtttgggtttagctgaaatggctgaagttaaagggcgattgaattta
catcaactcgatagcaagactaaattaatcgacgatacctataacgctaacgtcgaatca
atcaatgccgcatcagacttattggcgagttattcaggtcgtcgagtgcttattttgggc
gatatgggcgagttaggcgaagaagcacgtcgttatcaccaagaagttggcgaacatgcg
aaaaataagcatattgacgatttgttgaccttaggcgtattaagtcaacatgcctctgat
gccttttatcaaggacaagaggcacaggctcaacattttagtagtaaagaaaaattattg
tcacgattacagcagttacttcaaggtgaagaacagcaagtgactattttggttaaaggt
tcgcgcagtgctcatatggaatacgtagtggctgatattattcaatggcataacagtcag
actatgcaggagcaggcataa
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