Colwellia sp. PAMC 21821: A3Q33_11820
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Entry
A3Q33_11820 CDS
T04816
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
colw
Colwellia sp. PAMC 21821
Pathway
colw00260
Glycine, serine and threonine metabolism
colw00261
Monobactam biosynthesis
colw00270
Cysteine and methionine metabolism
colw00300
Lysine biosynthesis
colw01100
Metabolic pathways
colw01110
Biosynthesis of secondary metabolites
colw01120
Microbial metabolism in diverse environments
colw01230
Biosynthesis of amino acids
Module
colw_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
colw_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
colw_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
colw00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
A3Q33_11820 (thrA)
00270 Cysteine and methionine metabolism
A3Q33_11820 (thrA)
00300 Lysine biosynthesis
A3Q33_11820 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
A3Q33_11820 (thrA)
Enzymes [BR:
colw01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
A3Q33_11820 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
A3Q33_11820 (thrA)
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Paralog
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
ArsD
Motif
Other DBs
NCBI-ProteinID:
ARD44933
LinkDB
All DBs
Position
2776051..2778507
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AA seq
818 aa
AA seq
DB search
MRVLKFGGSSLASGQRFIEVANIIKNKSQSSRLAIVVSAPQGVTNHLVAMAENISNEEKL
QSDLLHFKHAIENIIQDLSARLPSFSSQHSEQVLATWEHQLSRYLHGATLLSFCPEHVRA
RIISIGERLSVALLQSVLSADAIEVSVIEPEKFLRTNDVSMNAVADLVLCKERFQHVYNE
LNTIALMPGFIGVDSLGNVTTLGRNGSDYSAAVLAVCSEAEYCEIWTDVDGVYNADPRLI
KEAQLLDYLSYQEAMELSYFGASVLHPKTIGPIAQHHIPCLIKNTGNPEAAGTLIANEND
QQKRVKAISNLDDLTMVNVSGPGMKGMVGMASRVFATMSRENISLILISQSSSEYCISFC
IYSSDADKAEQSLQEEFELELLNGLLEPLTLTHKLSIVSLVGDGMHHQQGVAAKFFSSLA
QARVNVVAIAQDSSERSISVVIESRKCTDAMKVSHQNFFSHKPTIDVFLVGCGVVGSELL
AQIARQQAKLTTDNISLKVYGLANSKGMVFNSEGIDVANWQENLGQEALPVTVENIKNFV
RANHLINPVLVDCTSNEALALQYVDYLEAGFNVVTPNKKANTDSWEYYQALRTAAQKTNR
RFLYETTVGAGLPVIDTLQNLLKAGDELVKFEGVLSGSLSYIFGKLDEGMTLSQATTLAK
EQGFTEPDPRDDLSGMDVARKLLIMAREAGMPLELTDIEIEPVLAESFDASGDVATFMSN
LPSLDQAFAERINVAKAEGKVLRYIGNIVDGKCQVAIEAVGVGHPLYSIKDGENALAVHS
RYYQPLPFVLRGYGAGAAVTAAGVFGDVLRTLAWEQQH
NT seq
2457 nt
NT seq
+upstream
nt +downstream
nt
atgcgtgtattaaaatttggtggttcgtctttggcttcgggtcagcgctttattgaagtg
gcgaacattatcaaaaataaaagtcagtcttctcgacttgctatagtcgtttctgcgcca
caaggcgtgactaatcatttagtggcgatggcagaaaatatctctaatgaagaaaaactg
caaagtgacttgttgcattttaaacacgctattgaaaacattatccaagacttgtcggcg
agattgccgagttttagctcgcaacacagtgagcaagtacttgcgacgtgggaacatcaa
ttaagccgatacttgcatggtgcaacattactgtcattttgtcctgaacatgtgcgtgca
cgtattattagcataggtgagcgtttgagtgtggcacttttgcagtcagtattgtcagcc
gatgcaatcgaagtgagtgttattgaacccgaaaaattccttcgcaccaatgatgtttcg
atgaatgccgtggcagacttagtgttatgtaaagaaagatttcagcatgtttataacgaa
cttaacacgattgcccttatgccaggttttatcggtgttgatagccttggtaatgttaca
acattaggtcgcaatggttcagattactctgctgcggtattagcggtttgtagtgaggct
gagtattgcgaaatttggacggacgttgacggtgtatataacgcagatcctcgcctaata
aaagaagcacaattattagattatttatcttaccaagaagcgatggagctatcttatttt
ggtgcgagtgttttacatccaaaaacaatcggtcctattgctcagcatcacattccttgt
ttgattaaaaataccggtaatcctgaagcagcaggaacgttaatcgctaatgaaaatgat
cagcaaaagcgtgttaaagcgatttcaaatttagatgacttaaccatggtgaatgtttct
ggccctggtatgaaaggcatggttggtatggcgagtcgtgtttttgctaccatgagtcgc
gaaaacatctctttaattttaatcagccagtcttcaagtgaatattgtattagtttttgt
atttattcgtctgatgcagataaagctgagcaaagcttacaagaagaattcgaattagaa
ttgttaaacggtttattagagccgttaacgttaacgcataaattatccattgtgtcttta
gttggcgatggtatgcatcatcaacaaggtgttgcggctaaatttttcagttcacttgcg
caagcacgtgtgaatgttgttgctattgctcaagactcgtcagagcgcagtatttctgtg
gttatcgaaagcagaaaatgtacagacgctatgaaagttagtcatcaaaacttcttttct
cacaagccaacaatagatgtattcttggttggttgtggtgttgtcggtagcgagttactg
gctcaaatagcccgccagcaggcaaaacttactacagacaatatttcactgaaagtttat
ggcttggctaacagtaaaggcatggtatttaacagtgaaggtatcgatgttgctaattgg
caagaaaatttaggccaagaagctttgccggttactgttgaaaatattaaaaactttgtt
cgtgcaaaccatttaattaacccggtattagttgattgtacttctaacgaagcacttgct
ttgcaatatgtggattatttagaagccggctttaatgttgtaacgcctaataagaaagcg
aacacagattcttgggaatattatcaagcattacgaacggcagctcaaaaaactaaccgt
cgatttttatacgaaacaacggttggcgctggcttaccggttattgatacgttgcaaaac
ttgctaaaagcgggtgatgagctggtaaaatttgaaggggtattatcaggttctttatcg
tatatattcggtaaacttgatgagggtatgactttatctcaagcaacaacgttagctaaa
gagcagggctttacagagcctgatcctcgtgatgacctgagcggtatggacgtagcgcgt
aagctgcttatcatggctagagaagcgggtatgccgttagagttaactgacatcgaaatc
gaaccggttttagccgagtcgttcgatgcaagcggtgacgtagcaacctttatgagtaat
ttaccatcgttagatcaggcattcgctgagcgcatcaatgtagctaaagcagaaggtaaa
gtgctgagatacattggtaatattgttgatggaaaatgtcaggtggctattgaagctgtc
ggcgtcggtcatccactttatagcattaaagatggcgaaaacgcgttagcggttcatagt
cgttattatcaaccgttaccttttgttttacgtggttatggcgctggtgctgcagttacc
gcagcaggtgtttttggtgacgtattaagaacattagcatgggagcaacagcactaa
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