Candida orthopsilosis: CORT_0C02530
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Entry
CORT_0C02530 CDS
T02488
Name
(RefSeq) Leu42 alpha-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
cot
Candida orthopsilosis
Pathway
cot00290
Valine, leucine and isoleucine biosynthesis
cot00620
Pyruvate metabolism
cot01100
Metabolic pathways
cot01110
Biosynthesis of secondary metabolites
cot01210
2-Oxocarboxylic acid metabolism
cot01230
Biosynthesis of amino acids
Module
cot_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
cot00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
CORT_0C02530
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CORT_0C02530
Enzymes [BR:
cot01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
CORT_0C02530
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GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-GeneID:
14539900
NCBI-ProteinID:
XP_003868532
UniProt:
H8X2T1
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All DBs
Position
3:550134..551864
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AA seq
576 aa
AA seq
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MPMLKDPSVKYKKFPPVNLPSRQWPSRTLDKAPRWLSTDLRDGNQSLPDPMSIEEKKEYF
KKLVDIGFKEIEVAFPSASQIDFDFTRFAIETAPADVSIQVLSPCREELIKRTVESLKGA
KRATVHIYLATSDCFRNVVFGLSKEESKELAVKCTKLVRKLTKDDPSTAGTDWDFEFSPE
TFSDTDLDYAVDVCEAVKEAWEPSKEKPIIFNLPATVEMSTPNVYADQIEYFATHISNRE
TVCISLHPHNDRGCSVAAAELGQLAGADRVEGCLFGNGERTGNVDLVTLALNLYTQGVSP
YLDFSDITSVINIVEKCNKIPVHARTPYGGSLVVCAFSGSHQDAIKKGFAAHHEKVKAAG
GKNVHWQLPYLPLDPEDIGRTYEAIIRVNSQSGKGGSAWVILRNLELDLPRGLQVAFSKV
VQQRAEVKGQELTNQELCDLFKQEYFIDYDEDDKEVADQHYKLIDYSIKTPDKGVKEIEA
EIEIDGKSVTIKGQGNGQLSAFNDALAKHLGIDFDVKHYHEHSLGEDANARAATYIEVVV
NKNITRWGVGINTDVSQASFLSLISILNGLKRNKDI
NT seq
1731 nt
NT seq
+upstream
nt +downstream
nt
atgcctatgttaaaagatccatcggtcaagtacaaaaagtttccaccagtaaatttacca
agccgtcagtggccaagtagaaccttggacaaggcgccaagatggctttccacagattta
agagacggtaatcaatctcttcctgatcctatgtccattgaggaaaagaaggaatatttc
aaaaagttagttgacattggtttcaaggagatcgaggtggcattcccgctggcttcacaa
attgattttgactttaccagatttgctattgaaactgcaccagcagatgtatcaattcag
gttctttcgccttgtcgcgaggagttgattaagagaacggtcgaatcacttaagggtgct
aagcgtgctacagttcatatatatttagccacatcggattgtttcagaaatgtggttttt
ggtttgagcaaggaagagagtaaagaattagcggtaaagtgtaccaaacttgttcgaaag
ttgacaaaagacgatccatcaactgctggaacagattgggattttgaattttcaccagaa
actttctctgatactgacttggattatgctgtggatgtgtgcgaggcggttaaagaggca
tgggaaccaagcaaggagaaaccaataattttcaacttaccggcaactgtcgaaatgtct
actccaaacgtatatgctgatcagattgagtactttgctacccacatcagtaatcgtgaa
accgtatgcatttcattacacccccacaatgatcgtgggtgtagtgtggctgccgctgag
ttgggtcagttagctggtgccgatcgtgttgaagggtgcctcttcggtaatggggaacgt
actggaaacgtcgatttagtcacattggctttgaacttgtacacgcaaggggtatcacca
tacttggacttttccgatatcacatctgtaataaatattgtagaaaagtgcaacaagata
ccagtccatgccagaaccccatatggcggttccttggttgtgtgtgcattcagtggttcg
catcaagatgctattaaaaagggtttcgctgctcaccacgaaaaagtcaaggctgcgggt
ggcaagaacgtacattggcaattgccatacttgccattggatccagaggatattggccgt
acttacgaagcaattatacgtgtcaactcacaatcaggtaaaggtggttcagcgtgggtc
attttgcgcaatttggagttggacttgccaagaggattacaagttgccttctctaaggtg
gtgcaacaacgtgctgaagtcaagggtcaagaacttaccaaccaagaattgtgtgacttg
tttaaacaagagtactttattgactacgacgaagacgataaggaagttgctgatcaacac
tataagttgattgactattcgataaagacaccagacaagggtgtgaaagaaatagaagcg
gaaatcgaaattgatggaaaatcggtaactatcaaaggccaaggtaacggtcaattatct
gctttcaacgacgctttagccaaacacttgggcattgatttcgatgtcaaacattatcac
gaacactctttgggtgaagatgccaatgccagagcagcaacttatatcgaagtggtggtc
aataagaatatcacgagatggggtgttggtatcaacactgatgtttcacaggcatctttc
ctttcattgatttctattctcaatggtttaaagaggaataaggatatctga
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