Colwellia sp. PAMC 20917: A3Q34_07725
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Entry
A3Q34_07725 CDS
T04511
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
coz
Colwellia sp. PAMC 20917
Pathway
coz00260
Glycine, serine and threonine metabolism
coz00261
Monobactam biosynthesis
coz00270
Cysteine and methionine metabolism
coz00300
Lysine biosynthesis
coz01100
Metabolic pathways
coz01110
Biosynthesis of secondary metabolites
coz01120
Microbial metabolism in diverse environments
coz01230
Biosynthesis of amino acids
Module
coz_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
coz_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
coz_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
coz00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
A3Q34_07725 (thrA)
00270 Cysteine and methionine metabolism
A3Q34_07725 (thrA)
00300 Lysine biosynthesis
A3Q34_07725 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
A3Q34_07725 (thrA)
Enzymes [BR:
coz01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
A3Q34_07725 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
A3Q34_07725 (thrA)
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GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
AOW76749
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Position
1818004..1820460
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AA seq
818 aa
AA seq
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MRVLKFGGSSLGSAERFVQVAKIIADKSNDSAVAVVVSAPQGVTNHLVAMAENISDEIKL
QNDLEHFRKAIITIIDDLGASLPKFSPLHAEQVLINWEHKLSRYLQGATMLSYCPDHIRA
IIISIGERLSVALLESVLNAQNIKTSVIEPEKFLITNEASLNAVADLVLSKENFENHYNN
LNKVALMPGFIGVNKQGQVTTLGRNGSDYSAAVLAVCAQAECCEIWTDVDGVFNADPRLI
KEAKLLDYLSYQEAMELSYFGASVLHPKTIGPIAQFHIPCLIKNTGNPDAPGTLISNEDD
QTKKVKAISNLDDLTMVNVSGPGMKGMVGMASRVFATMSQEKISLVLISQSSSEYCISFC
IHTSDAELAELSLQQEFELELLNGLLEPLKLQHELSIISLVGDGMHHQQGVAAKFFSSLA
QARVNVIAIAQDSSERSISVVVEKRKCTDAMKVSHQNFFTHKPTIDVFLVGCGVVGSELL
AQIARQQPKLKKQNISLKVYGIANSKGMVFNTEGIDLDNWQAEMKSDAVPVNVENIKAFV
RENHLINPVLVDSTSSESLAMSYVEYLEEGFNIVTPNKKANTDSWQYYQALRSAAQKSNR
RFLYETTVGAGLPVIDTLQSLLKAGDELVRFEGILSGSLSYMFGKLEEGMTVSQATAIAK
ENGFTEPDPRDDLSGMDVARKLLIMAREAGIPLELSDISIESVLPANFDASGDVSEFMKN
LAKIDDEFSQRVKVAKAEGKVLRYIGNIVDGKCKVAIEAVANDHPLYSVKDGENALAIHS
RYYQPLPFVLRGYGAGAAVTAAGVFGDLLRTLAWEQQH
NT seq
2457 nt
NT seq
+upstream
nt +downstream
nt
atgcgtgtattaaagtttggaggttcatctctagggtcagcagaacgttttgtgcaagtt
gccaaaattatagctgacaaaagtaacgattctgctgttgccgttgttgtttccgcccca
caaggcgtaaccaaccatttagtggctatggcagagaatattagtgatgaaataaaatta
caaaatgatttagaacacttcagaaaagccattataaccattatcgatgatcttggtgcc
agcttaccaaaattcagcccattacatgcagagcaagtccttataaactgggagcataag
ctttcacgttatctacaaggcgcaactatgttgtcttattgcccggatcatatccgcgct
ataattatcagcataggtgagcgtttaagtgttgccttgctcgaatcagtgttgaacgca
caaaatattaaaacgtctgttattgaaccagaaaaatttttaatcaccaacgaagcgtct
cttaatgcagtcgctgatttagtcttatcaaaagaaaacttcgaaaaccattacaacaat
ctcaataaagttgccttaatgccgggtttcatcggtgttaacaaacaagggcaagtaacg
acacttggccgcaatggttctgattactctgctgccgttctcgcggtttgtgctcaagct
gaatgttgtgaaatatggacggatgttgatggtgtttttaacgcagatcctcgtctaata
aaggaagcaaaattacttgattacttgtcatatcaagaagcgatggaactttcatatttt
ggtgctagcgtgctacacccaaaaacgattggccccatagctcaatttcatattccttgt
ttgattaaaaataccggtaatcctgatgcgccaggaaccttaatatctaacgaggatgat
caaactaaaaaagttaaagcgatatctaatcttgatgatttaactatggtcaatgtctca
ggaccgggtatgaaaggtatggttggcatggcaagtcgtgtatttgccactatgagtcaa
gaaaaaatttctttagtcttaattagccagtcttccagcgaatactgtatcagtttttgt
attcacaccagtgatgctgaattagccgaactaagcttacaacaagagttcgagctggaa
ttactcaatggtttacttgaaccgttgaagttacaacatgaattatcgattatttctctg
gttggtgacggtatgcatcaccaacaaggggttgctgctaagtttttcagttcattagcc
caagcacgtgtcaatgtcatcgctattgcccaagattcgtcagagcgaagtatttctgtt
gtggtagaaaaacgtaaatgtactgatgcaatgaaagtcagtcatcaaaatttcttcacc
cacaaacccactattgatgtattccttgttggttgcggtgttgttggtagtgaacttctt
gcgcaaattgctcgtcaacaacctaagcttaaaaagcaaaatatttccttaaaggtttac
ggcattgctaacagtaaaggtatggtttttaatactgaaggtattgatttagataactgg
caagcagaaatgaaaagtgacgcagttccagtaaatgttgaaaacatcaaggcttttgtc
cgcgagaatcacctgattaacccggtgttagtcgactcaacctctagtgagtctttagcg
atgagctatgtagagtaccttgaagagggttttaatattgtaacgccaaataaaaaagcc
aatactgactcttggcaatactatcaagcgttgcgcagtgcagcacagaagtctaaccgt
cgcttcttatatgaaacaacagttggtgctggcttacccgtaattgataccttacaaagc
ttgctaaaagcgggtgatgaattagtacgttttgaagggatattgtctggttcactttcc
tatatgtttggaaaactagaagaaggtatgaccgtttctcaagccaccgctatcgccaaa
gaaaatggctttaccgagcctgaccctcgtgacgatttaagcggtatggacgtagcgcgt
aaattgttaatcatggcgcgtgaagcaggaataccgcttgagttatcagatatctctata
gaatctgtgttacctgcaaactttgatgcgagtggtgatgtcagtgaatttatgaagaac
ttagcgaaaatagatgatgaattttctcaacgagtaaaagtcgcaaaagctgaaggtaaa
gttttacgttatatcggcaatatagttgatggaaaatgtaaagttgccattgaagctgtt
gccaatgatcatccactttatagtgttaaagatggtgaaaatgcgttggcaatacatagc
cgttattaccaacccttaccgtttgtattacgcggttatggcgcaggtgctgcggttacc
gccgcaggtgtgtttggcgatctattaagaacattagcatgggagcagcagcactaa
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