KEGG   Chiloscyllium plagiosum (whitespotted bambooshark): 122540870
Entry
122540870         CDS       T08871                                 
Symbol
map2k1
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 1
  KO
K04368  mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
Organism
cpla  Chiloscyllium plagiosum (whitespotted bambooshark)
Pathway
cpla04010  MAPK signaling pathway
cpla04012  ErbB signaling pathway
cpla04068  FoxO signaling pathway
cpla04114  Oocyte meiosis
cpla04140  Autophagy - animal
cpla04148  Efferocytosis
cpla04150  mTOR signaling pathway
cpla04210  Apoptosis
cpla04218  Cellular senescence
cpla04270  Vascular smooth muscle contraction
cpla04370  VEGF signaling pathway
cpla04371  Apelin signaling pathway
cpla04510  Focal adhesion
cpla04540  Gap junction
cpla04620  Toll-like receptor signaling pathway
cpla04810  Regulation of actin cytoskeleton
cpla04910  Insulin signaling pathway
cpla04912  GnRH signaling pathway
cpla04914  Progesterone-mediated oocyte maturation
cpla04916  Melanogenesis
cpla05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:cpla00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    122540870 (map2k1)
   04012 ErbB signaling pathway
    122540870 (map2k1)
   04370 VEGF signaling pathway
    122540870 (map2k1)
   04371 Apelin signaling pathway
    122540870 (map2k1)
   04068 FoxO signaling pathway
    122540870 (map2k1)
   04150 mTOR signaling pathway
    122540870 (map2k1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    122540870 (map2k1)
   04148 Efferocytosis
    122540870 (map2k1)
  09143 Cell growth and death
   04114 Oocyte meiosis
    122540870 (map2k1)
   04210 Apoptosis
    122540870 (map2k1)
   04218 Cellular senescence
    122540870 (map2k1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    122540870 (map2k1)
   04540 Gap junction
    122540870 (map2k1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    122540870 (map2k1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    122540870 (map2k1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    122540870 (map2k1)
   04912 GnRH signaling pathway
    122540870 (map2k1)
   04914 Progesterone-mediated oocyte maturation
    122540870 (map2k1)
   04916 Melanogenesis
    122540870 (map2k1)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    122540870 (map2k1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    122540870 (map2k1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cpla01001]
    122540870 (map2k1)
Enzymes [BR:cpla01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     122540870 (map2k1)
Protein kinases [BR:cpla01001]
 Serine/threonine kinases: STE group
  STE7 family
   122540870 (map2k1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Pkinase_fungal Haspin_kinase Kinase-like Seadorna_VP7
Other DBs
NCBI-GeneID: 122540870
NCBI-ProteinID: XP_043533025
LinkDB
Position
36:210010..264764
AA seq 393 aa
MPKKKPGPIQLHPSPDGSALNGTTSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKV
GELKDDDFEKISELGAGNGGVVFKVSHKPSSLIMARKLIHLEIKPAIRNQIIRELQVLHE
CNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRITEQVLGKVSIAVNKGLAYL
REKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHY
SVQSDIWSMGLSLVEMAIGRYPIPPPDAKELEQIFGCHVGEDPSSSESSPQPSGRPGSSF
GGDCRPPMAIFELLDYIVNEPPPKLPTGVFSEEFQDFVNACLIKNPAERADLKQLMAHAF
IKRSEAEEVDFAGWLCTTIGLKQPSTPTHTPTV
NT seq 1182 nt   +upstreamnt  +downstreamnt
atgcccaagaagaagccgggaccgatccagctgcacccaagtcccgatggctcggctctg
aatgggaccacttccgcagagacaaatctggaagctctgcaaaagaagttagaggagctc
gagttggatgaacaacagcgcaaacgtttggaagcatttctgacccagaaacagaaagtt
ggcgagttgaaagatgatgactttgagaagatatcggaactgggagcaggaaatggagga
gtagttttcaaagtttctcacaaaccatccagccttataatggcccggaagctaattcac
ctggaaatcaagccagccattcggaatcagataatccgagaattacaggttctgcatgaa
tgtaactctccatatatcgtgggattctatggagctttctacagtgatggagagatcagc
atctgcatggaacacatggatggtggatcactggatcaggtgcttaaaaaggctggaaga
attacagagcaagtgctgggtaaagtgagcatagctgtgaacaagggattggcatatctg
cgagagaaacacaagatcatgcaccgagatgttaaaccttcaaacatcttggtgaattcc
cgcggtgaaatcaaactttgtgattttggggttagtgggcagctgattgactccatggca
aactcctttgttgggacaagatcttacatgtcacctgaaagactccaggggacacattat
tctgttcaatccgatatctggagtatggggctgtctctggtggagatggccattggaagg
tatccaattcctccacctgatgctaaggagctcgaacagatctttggctgtcacgtggga
gaggacccttcatcctccgagtcaagccctcaaccttcaggacgtccagggagttctttt
ggtggtgattgtcgacctccaatggcaatattcgaattgttggattacattgtgaatgag
ccacctcctaaattgccaactggagtatttagtgaagaatttcaagactttgtgaatgca
tgtttgataaagaatcctgcggaaagagcagacctgaagcagcttatggctcatgctttc
atcaaacgatcagaggcggaagaggtggatttcgcaggttggctgtgcacgactattggc
ctgaagcagccaagtacaccaacgcatactcctactgtgtag

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