Cavia porcellus (domestic guinea pig): 100135485
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Entry
100135485 CDS
T07777
Symbol
Bace1
Name
(RefSeq) beta-secretase 1 precursor
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
cpoc
Cavia porcellus (domestic guinea pig)
Pathway
cpoc05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
cpoc00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100135485 (Bace1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
cpoc01002
]
100135485 (Bace1)
Enzymes [BR:
cpoc01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
100135485 (Bace1)
Peptidases and inhibitors [BR:
cpoc01002
]
Aspartic peptidases
Family A1: pepsin family
100135485 (Bace1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
PE-PGRS_C
Motif
Other DBs
NCBI-GeneID:
100135485
NCBI-ProteinID:
NP_001166390
Ensembl:
ENSCPOG00000012754
UniProt:
Q1KLR6
LinkDB
All DBs
AA seq
473 aa
AA seq
DB search
MAPALPWLLLWVGSGVLPVHGTQDGIRLPLRSGLAGAPLGLRLPRETDEEPGRRGSFVEM
VDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQRSSTYRD
LRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLA
YAEIARLCGAGFPLNQSEAVASVGGSMIIGGIDHSLYTGNLWYTPIRREWYYEVIIVRVE
INGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQL
VCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQS
STGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTATVEGPFVTPDMEDCGYNIP
QTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRHQHDDFADDISLLK
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
atggccccggccctgccctggctcctgctgtgggtgggctcgggagtgctgcctgtccac
ggcacccaggatggcatccgactgcccctgcgcagcggcctggcaggggcccccctgggg
ctgcggctgccccgggagaccgacgaggagcctggcaggaggggcagcttcgtggagatg
gtggacaacctgaggggaaagtcgggccagggctactacgtggagatgaccgtgggcagc
cccccgcagacgctcaacatcctggtggacacaggcagcagtaactttgcagtgggggcg
gccccccaccctttcctgcatcgctattatcaaaggcagcggtcaagcacgtatcgggac
ctccgaaagggcgtgtatgtgccctacacccagggcaagtgggagggggagctgggcact
gacctggtgagcattcctcatggtcccaacgtcactgtgcgtgcgaacatcgctgccatc
acggaatcagacaagttcttcatcaatggctccaactgggagggcatcctggggctggcc
tacgccgagatcgccaggctctgtggtgcaggcttccccctcaaccagtctgaggccgtg
gcttctgtgggagggagcatgatcatcgggggtattgaccactcgctgtatacaggcaat
ctctggtatacacccatccggcgggagtggtattatgaggtgatcattgtgcgggtggag
atcaatggacaagatctgaagatggactgcaaggagtacaactatgacaagagcatcgtg
gacagtggcaccaccaaccttcgtctccccaagaaagtgtttgaggctgcggtcaaatcc
atcaaggcagcctcctcgacagagaagtttccagatggcttttggctgggtgagcagctg
gtgtgctggcaagcaggcaccaccccctggaacattttcccagtcatctcgctctacctc
atgggtgaggtcaccaaccagtccttccgcatcaccattcttccacagcaatacctgcgg
cctgtggaagacgtagccacgtcccaggatgactgttacaagttcgccatctcgcagtca
tccactggcacggtgatgggagctgttatcatggagggcttctacgtcgtctttgaccgg
gcccgaaaacgaatcggctttgctgtcagtgcttgccatgtgcatgatgagttcaggacc
gcaacagtggaaggcccttttgtcaccccggacatggaagactgtggctacaacattcca
cagacagatgagtcaaccctcatgaccatagcctatgtcatggctgccatctgcgccctc
ttcatgctgccactctgcctcatggtgtgtcagtggcgctgcctccgctgcctccgccat
caacatgatgactttgctgatgacatctccctgctgaagtga
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