KEGG   Cavia porcellus (domestic guinea pig): 100135528
Entry
100135528         CDS       T07777                                 
Symbol
Gnai1
Name
(RefSeq) guanine nucleotide-binding protein G(i) subunit alpha-1
  KO
K04630  guanine nucleotide-binding protein G(i) subunit alpha
Organism
cpoc  Cavia porcellus (domestic guinea pig)
Pathway
cpoc04015  Rap1 signaling pathway
cpoc04022  cGMP-PKG signaling pathway
cpoc04024  cAMP signaling pathway
cpoc04062  Chemokine signaling pathway
cpoc04071  Sphingolipid signaling pathway
cpoc04081  Hormone signaling
cpoc04082  Neuroactive ligand signaling
cpoc04261  Adrenergic signaling in cardiomyocytes
cpoc04360  Axon guidance
cpoc04371  Apelin signaling pathway
cpoc04540  Gap junction
cpoc04611  Platelet activation
cpoc04670  Leukocyte transendothelial migration
cpoc04713  Circadian entrainment
cpoc04723  Retrograde endocannabinoid signaling
cpoc04724  Glutamatergic synapse
cpoc04725  Cholinergic synapse
cpoc04726  Serotonergic synapse
cpoc04727  GABAergic synapse
cpoc04728  Dopaminergic synapse
cpoc04730  Long-term depression
cpoc04914  Progesterone-mediated oocyte maturation
cpoc04915  Estrogen signaling pathway
cpoc04916  Melanogenesis
cpoc04921  Oxytocin signaling pathway
cpoc04923  Regulation of lipolysis in adipocytes
cpoc04924  Renin secretion
cpoc04926  Relaxin signaling pathway
cpoc04928  Parathyroid hormone synthesis, secretion and action
cpoc04934  Cushing syndrome
cpoc04935  Growth hormone synthesis, secretion and action
cpoc04971  Gastric acid secretion
cpoc05012  Parkinson disease
cpoc05030  Cocaine addiction
cpoc05032  Morphine addiction
cpoc05034  Alcoholism
cpoc05133  Pertussis
cpoc05142  Chagas disease
cpoc05145  Toxoplasmosis
cpoc05163  Human cytomegalovirus infection
cpoc05170  Human immunodeficiency virus 1 infection
cpoc05200  Pathways in cancer
cpoc05207  Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:cpoc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100135528 (Gnai1)
   04371 Apelin signaling pathway
    100135528 (Gnai1)
   04071 Sphingolipid signaling pathway
    100135528 (Gnai1)
   04024 cAMP signaling pathway
    100135528 (Gnai1)
   04022 cGMP-PKG signaling pathway
    100135528 (Gnai1)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    100135528 (Gnai1)
   04081 Hormone signaling
    100135528 (Gnai1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    100135528 (Gnai1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100135528 (Gnai1)
   04670 Leukocyte transendothelial migration
    100135528 (Gnai1)
   04062 Chemokine signaling pathway
    100135528 (Gnai1)
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    100135528 (Gnai1)
   04915 Estrogen signaling pathway
    100135528 (Gnai1)
   04914 Progesterone-mediated oocyte maturation
    100135528 (Gnai1)
   04921 Oxytocin signaling pathway
    100135528 (Gnai1)
   04926 Relaxin signaling pathway
    100135528 (Gnai1)
   04935 Growth hormone synthesis, secretion and action
    100135528 (Gnai1)
   04928 Parathyroid hormone synthesis, secretion and action
    100135528 (Gnai1)
   04916 Melanogenesis
    100135528 (Gnai1)
   04924 Renin secretion
    100135528 (Gnai1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100135528 (Gnai1)
  09154 Digestive system
   04971 Gastric acid secretion
    100135528 (Gnai1)
  09156 Nervous system
   04724 Glutamatergic synapse
    100135528 (Gnai1)
   04727 GABAergic synapse
    100135528 (Gnai1)
   04725 Cholinergic synapse
    100135528 (Gnai1)
   04728 Dopaminergic synapse
    100135528 (Gnai1)
   04726 Serotonergic synapse
    100135528 (Gnai1)
   04730 Long-term depression
    100135528 (Gnai1)
   04723 Retrograde endocannabinoid signaling
    100135528 (Gnai1)
  09158 Development and regeneration
   04360 Axon guidance
    100135528 (Gnai1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100135528 (Gnai1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100135528 (Gnai1)
   05207 Chemical carcinogenesis - receptor activation
    100135528 (Gnai1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100135528 (Gnai1)
   05163 Human cytomegalovirus infection
    100135528 (Gnai1)
  09171 Infectious disease: bacterial
   05133 Pertussis
    100135528 (Gnai1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100135528 (Gnai1)
   05142 Chagas disease
    100135528 (Gnai1)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    100135528 (Gnai1)
  09165 Substance dependence
   05030 Cocaine addiction
    100135528 (Gnai1)
   05032 Morphine addiction
    100135528 (Gnai1)
   05034 Alcoholism
    100135528 (Gnai1)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100135528 (Gnai1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cpoc04147]
    100135528 (Gnai1)
   04031 GTP-binding proteins [BR:cpoc04031]
    100135528 (Gnai1)
Exosome [BR:cpoc04147]
 Exosomal proteins
  Proteins found in most exosomes
   100135528 (Gnai1)
GTP-binding proteins [BR:cpoc04031]
 Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 1 (Gi/o) [OT]
    100135528 (Gnai1)
SSDB
Motif
Pfam: G-alpha Arf Gtr1_RagA TniB FtsK_SpoIIIE AAA_29
Other DBs
NCBI-GeneID: 100135528
NCBI-ProteinID: NP_001166424
Ensembl: ENSCPOG00000039890
UniProt: P38401
LinkDB
AA seq 354 aa
MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAG
YSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMT
AELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQSNYIPTQQDVLRTRVK
TTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYTGSNTYEEAA
AYIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
NT seq 1065 nt   +upstreamnt  +downstreamnt
atgggctgcacgctgagcgccgaggacaaggcggccgtggagcgcagcaagatgatcgac
cgcaacctgcgcgaggacggcgagaaggcggcgcgcgaggtcaagctgctgctgctcggt
gctggtgagtctgggaaaagtaccattgtaaagcagatgaaaattatccacgaggcgggg
tattcggaagaggagtgcaagcagtacaaagccgtggtctacagcaacaccatccagtcc
atcattgctattatcagggccatgggaagactgaagattgacttcggggactcagcgcgg
gcggatgacgcccgccaactctttgtgctcgctggggccgcagaagaaggttttatgacg
gcagaactcgctggtgttataaagagattgtggaaagatagtggcgtgcaagcctgtttc
aacagatcccgggagtaccagctgaacgactctgcagcgtactatttgaatgatttggac
cgaatcgcacaatcgaactatatcccaacgcagcaagatgtgctcagaaccagagtgaaa
acgactgggattgtggaaacccacttcaccttcaaagaccttcattttaagatgtttgac
gtgggcggccagcgctccgagaggaagaagtggatccactgcttcgagggggtgactgcc
attatcttctgtgtggccctgagcgactacgacctggtgctggcagaggatgaagaaatg
aaccgaatgcatgaaagcatgaagttgttcgacagcatatgcaacaacaagtggtttacg
gatacgtccatcatactcttcctaaacaagaaggatcttttcgaggaaaaaatcaagaag
agccctctcaccatatgctatccggagtatacaggctcaaacacatatgaagaggcagct
gcctatattcagtgtcagtttgaggacctgaataagaggaaagacacgaaggaaatctac
acccacttcacctgcgccaccgacaccaagaacgtgcagttcgtcttcgacgccgtgacc
gacgtcatcataaagaataacctgaaggactgtggtctcttctaa

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