Cavia porcellus (domestic guinea pig): 100135576 Help Entry 100135576         CDS       T07777                                  Symbol Nos2 Name (RefSeq) nitric oxide synthase, inducible   KO K13241   nitric-oxide synthase, inducible [EC:1.14.13.39] Organism cpoc  Cavia porcellus (domestic guinea pig) Pathway cpoc00220   Arginine biosynthesis cpoc00330   Arginine and proline metabolism cpoc01100   Metabolic pathways cpoc04020   Calcium signaling pathway cpoc04066   HIF-1 signaling pathway cpoc04146   Peroxisome cpoc04371   Apelin signaling pathway cpoc04926   Relaxin signaling pathway cpoc05010   Alzheimer disease cpoc05014   Amyotrophic lateral sclerosis cpoc05022   Pathways of neurodegeneration - multiple diseases cpoc05133   Pertussis cpoc05140   Leishmaniasis cpoc05142   Chagas disease cpoc05145   Toxoplasmosis cpoc05146   Amoebiasis cpoc05152   Tuberculosis cpoc05200   Pathways in cancer cpoc05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:cpoc00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     100135576 (Nos2)    00330 Arginine and proline metabolism     100135576 (Nos2)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     100135576 (Nos2)    04066 HIF-1 signaling pathway     100135576 (Nos2)    04020 Calcium signaling pathway     100135576 (Nos2)  09140 Cellular Processes   09141 Transport and catabolism    04146 Peroxisome     100135576 (Nos2)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     100135576 (Nos2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100135576 (Nos2)   09162 Cancer: specific types    05222 Small cell lung cancer     100135576 (Nos2)   09171 Infectious disease: bacterial    05133 Pertussis     100135576 (Nos2)    05152 Tuberculosis     100135576 (Nos2)   09174 Infectious disease: parasitic    05146 Amoebiasis     100135576 (Nos2)    05145 Toxoplasmosis     100135576 (Nos2)    05140 Leishmaniasis     100135576 (Nos2)    05142 Chagas disease     100135576 (Nos2)   09164 Neurodegenerative disease    05010 Alzheimer disease     100135576 (Nos2)    05014 Amyotrophic lateral sclerosis     100135576 (Nos2)    05022 Pathways of neurodegeneration - multiple diseases     100135576 (Nos2) Enzymes [BR:cpoc01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      100135576 (Nos2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 NAD_binding_6 Carb_kinase Motif Other DBs NCBI-GeneID:  100135576 NCBI-ProteinID:  NP_001166455 Ensembl:  ENSCPOG00000011017 UniProt:  O54705 LinkDB All DBs AA seq 1149 aa AA seqDB search MACPWNFLWKLKSSRYDLTEEKDINNNVGKASHLYSPEIQDDPKYCSPGKHQNGSSQSLT GTAKKVPESQSKPHKPSPTCSQHMKIKNWGNGMILQDTLHTKAKTNFTCKPKSCLGSVMN PRSMTRGPRDTPIPPDELLPQAIEFVNQYYDSFKEAKIEEYLARVETVTKEIETTGTYQL TGDELIFATKLAWRNAPRCIGRIQWSNLQVFDARSCHTAQEMFEHICRHVRYSTNNGNIR SAITVFPQRTDGKHDFRVWNAQLIRYAGYQMPDGTIQGDPANLEFTQLCIDLGWKPRYGR FDVLPLILQADGRDPELFEIPPDLVLEVPMEHPKYEWFQDLGLKWYALPAVANMLLEVGG LEFPACPFNGWYMGTEIGVRDFCDAQRYNILEEVGRRMGLETHTLASLWKDRAVTEINVA VLHSFQKQNVTIMDHHSAAESFMKHMQNEYRARGGCPADWIWLVPPISGSITPVFHQEML NYILSPFYYYQVEAWKTHVWQDETRRPKRREIPFRVLAKATLFASLLMRKMMASRVRATI LFATETGKSEALAQDLGALFSCAFNPKVLCMDQYQLSSLEEEKLLLVVTSTFGNGDCPGN GETLKKSLFVLKKLTNTFRYAVFGLGSSMYPRFCAFAHDIDIKLSQLGASQLTPVGEGDE LSGQEDAFCTWAVQTFQAACAAFDVRGRHHITIPKRYTSSVTWEPYHYRLVQDSQPLDLN KALSRMHATDVFTMRLKSQKNLQSPKSSRTTLLMELSCDDSRSLAYLPGEHLGVFPCNQP ALVQGILECVVDNPGPHHTVCLEVLDDSGSYWAKDKRLPPCSLSQALTYFLDITTPPTQL QLQKLARLATEQAERLRLESLSQPSEYNKWKFTNSPTFLEVLEEFPSLRVPAAFLLSQLP ILKPRYYSISSSLDHTPAEVHLTVAVVTYRTRDGRGPLHHGVCSTWFSGLKPQDPVPCLV RSVNSFQLPKDPSQPCILIGPGTGIAPFRSFWQQRLHNLKHTGLQGGRMTLLFGCRHPEE DHIYKEEMQEMVQKGVLHEVHTAYSRLPGKPKAYVQDILRQQLAREVLRVLHEEPGHLYV CGNVLMAQDVACTLKQLLAAKLNLNEEQVEDYFFQLKSQKRYHEDIFGAVFPHGVKKDRA ERPPGDDKL NT seq 3450 nt NT seq  +upstreamnt  +downstreamnt atggcctgcccctggaatttcctgtggaagctcaaatccagtcggtatgacttgacagag gaaaaggacatcaacaacaacgtgggaaaagccagtcatctctacagcccagaaatacaa gatgaccccaaatactgcagccctggcaagcaccaaaacggatcctcccagtcccttaca gggactgccaagaaggttccagaatcccagagcaagccacataagccttcaccaacctgt tcccagcacatgaagatcaaaaactggggcaatgggatgattttgcaagacacactgcac accaaggccaaaacgaactttacttgcaagccaaaatcttgccttgggtccgtgatgaac cctagaagtatgaccagaggccccagggacacgcctatccctccggatgagcttctacct caagctattgaatttgtcaaccagtattacgactccttcaaagaggcaaaaatagaggaa tatctggccagagtggaaacggtaacaaaggagatagaaacaacaggaacctaccagctg acaggagatgagctcatcttcgccaccaagctcgcctggcgcaatgcccctcgctgcatc gggaggatacagtggtccaacctgcaggtgttcgatgcccgcagctgtcacacagcccag gagatgtttgagcacatctgcaggcacgtgcgttactctaccaacaacggcaacatcagg tcggccatcaccgtgttcccccagcggactgatgggaagcatgacttccgtgtctggaat gcccagctcatccggtacgctggctaccagatgccagatggcaccatccaaggggaccct gccaacctggagttcacacagctgtgcattgacctgggctggaagcctcgctatggccgc tttgatgtgctgcctctgatcctgcaggctgatggccgtgaccccgagctctttgaaatt ccgcctgatcttgtgcttgaggtgcccatggagcatcccaagtatgagtggttccaggac ctggggttgaagtggtatgctctgcctgcggtggccaacatgctgcttgaggtgggcggc cttgagttcccagcatgccccttcaatggctggtacatgggcacggagatcggagtccgg gacttctgtgatgcccagcgctacaacatcctggaggaagtgggcaggaggatgggcctg gagacgcacacgttggcttccctctggaaagaccgtgccgtcacggagatcaatgttgct gtgctgcatagtttccagaagcagaacgtgaccatcatggaccaccactctgcagcggag tccttcatgaagcacatgcagaatgagtaccgggcccgtgggggctgcccggcggactgg atttggctggtccctcctatttcagggagcatcacccccgtgtttcaccaggagatgctg aactacatcctgtccccattctactactatcaggtggaagcctggaagacccatgtgtgg caggatgaaactcggagacccaaaagacgagagatcccattcagagtcttggcaaaagcc acgctctttgcctctctgctgatgcgcaagatgatggcctcccgagtcagagccacaatc cttttcgccacagagaccggaaaatcagaagcactggcccaggacctaggggccttgttc agttgtgctttcaaccccaaggttctctgcatggatcagtaccagctgagtagcctggag gaggagaagctcctgctggtggtgaccagcacgttcgggaacggagactgccctggcaat ggagagacactgaagaaatccctcttcgtgctgaaaaagctcaccaataccttcaggtat gctgtgtttggccttggctccagtatgtatcctcgcttctgtgcctttgctcatgacatc gacataaagttatcccaactgggggcctctcagctcaccccagtgggggaaggggacgaa ctcagcgggcaggaggacgccttctgcacctgggctgtgcaaaccttccaggcagcctgt gccgcattcgatgttcgaggcagacaccacatcaccatccccaagcgctacacctccagc gtgacctgggagccataccactacaggctggtgcaggattcgcagcctttggacctcaac aaagccctcagtaggatgcatgccacggatgtgttcaccatgcgactcaagtcccagaag aatctgcagagtccaaaatccagtcgcactaccctcctgatggaactttcctgtgatgac agccgaagcctggcttacctgcccggggagcaccttggggttttcccgtgcaaccagcca gccctggtccaaggcatcttggagtgtgtggtggacaaccctggaccccaccacaccgtg tgccttgaggtcctggatgacagtggcagctactgggccaaggacaagcggctgcccccc tgctccctgagccaggccctcacctacttcctggacatcaccacacccccgactcagctg caactccagaagctggcccggctggccacggagcaggctgagagactgaggctggagagt ctgagccagccctcagagtacaacaaatggaagttcaccaacagccccacgttcctggag gtcctggaggagttcccgtcactgcgggtgcctgctgccttcttgctctcccagctcccc attctgaagccccgatactactccatcagctcctccctggaccacactcccgcagaggtg cacctcactgtggccgtggtcacctaccgcacccgagatggtcggggtcccctgcatcat ggcgtctgcagcacctggttcagtggcttgaagccccaggacccagtgccctgtctcgtt cggagtgtcaacagcttccagctccccaaggacccctcccagccctgcatcctcattggg cctggcacaggcattgcacccttccgcagtttctggcagcagcggcttcacaatctcaaa cacacagggctccagggtggccgaatgacgctcctgtttggatgtcgccacccggaggaa gatcacatctataaggaagagatgcaggagatggtccagaagggggtgctgcatgaagtg cacacagcctactcacggctgcctggaaagcccaaggcgtatgtccaagacatcctgcgg cagcagctggccagggaggtgctccgtgtgctccacgaggagccgggccacctctacgtc tgtgggaatgtgctcatggcccaggacgtggcctgcacgttgaagcagctgctagctgcc aagctgaacttgaacgaggagcaggttgaggattacttcttccagctcaagagccagaag cgctatcacgaagatatctttggtgctgtctttccccatggggtgaagaaggaccgggca gagcggccccccggcgacgacaagctctga

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