Cavia porcellus (domestic guinea pig): 100174978
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Entry
100174978 CDS
T07777
Symbol
Atp2a2
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
cpoc
Cavia porcellus (domestic guinea pig)
Pathway
cpoc04020
Calcium signaling pathway
cpoc04022
cGMP-PKG signaling pathway
cpoc04024
cAMP signaling pathway
cpoc04148
Efferocytosis
cpoc04260
Cardiac muscle contraction
cpoc04261
Adrenergic signaling in cardiomyocytes
cpoc04380
Osteoclast differentiation
cpoc04919
Thyroid hormone signaling pathway
cpoc04972
Pancreatic secretion
cpoc05010
Alzheimer disease
cpoc05017
Spinocerebellar ataxia
cpoc05022
Pathways of neurodegeneration - multiple diseases
cpoc05410
Hypertrophic cardiomyopathy
cpoc05412
Arrhythmogenic right ventricular cardiomyopathy
cpoc05414
Dilated cardiomyopathy
cpoc05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
cpoc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
100174978 (Atp2a2)
04024 cAMP signaling pathway
100174978 (Atp2a2)
04022 cGMP-PKG signaling pathway
100174978 (Atp2a2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100174978 (Atp2a2)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
100174978 (Atp2a2)
09153 Circulatory system
04260 Cardiac muscle contraction
100174978 (Atp2a2)
04261 Adrenergic signaling in cardiomyocytes
100174978 (Atp2a2)
09154 Digestive system
04972 Pancreatic secretion
100174978 (Atp2a2)
09158 Development and regeneration
04380 Osteoclast differentiation
100174978 (Atp2a2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100174978 (Atp2a2)
05017 Spinocerebellar ataxia
100174978 (Atp2a2)
05022 Pathways of neurodegeneration - multiple diseases
100174978 (Atp2a2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100174978 (Atp2a2)
05412 Arrhythmogenic right ventricular cardiomyopathy
100174978 (Atp2a2)
05414 Dilated cardiomyopathy
100174978 (Atp2a2)
05415 Diabetic cardiomyopathy
100174978 (Atp2a2)
Enzymes [BR:
cpoc01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
100174978 (Atp2a2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
100174978
NCBI-ProteinID:
XP_003462979
Ensembl:
ENSCPOG00000002739
UniProt:
A0A286XD73
LinkDB
All DBs
Position
Unknown
AA seq
997 aa
AA seq
DB search
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKVMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDKVEGDTCSLNEFTITGSTYAPMGEVHKDDKPIKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANVCNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVLMTPGV
KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL
SPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAVFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNLTQWLMVLKISLPVILMDETLKFVARNYLEPAILE
NT seq
2994 nt
NT seq
+upstream
nt +downstream
nt
atggagaacgcgcacacaaagacggtggaggaggtgctgggccacttcggtgtcaacgag
agcacggggctgagtctggagcaggtcaagaagctcaaggagagatggggctccaacgag
ttaccggctgaagaaggaaaaaccttgctagaactagtgattgaacagtttgaagactta
ctagttagaattttattgctggcagcatgtatatcttttgttttggcttggtttgaagaa
ggtgaagaaaccatcacagcctttgtagaaccttttgtaattctacttatattagtagcc
aatgcaattgtaggtgtgtggcaggaaaggaatgctgaaaatgcaatcgaagccctcaag
gaatatgagcctgaaatgggcaaagtgtatcggcaggacaggaagagtgtgcagcggatt
aaagctaaagacatagttcctggggatattgtagaaattgctgttggtgacaaagttcct
gctgatataagattaacttccatcaagtctacaactctaagagtcgaccagtctattctc
actggtgaatccgtttcagtcatcaagcacactgaccctgtccctgacccacgggctgtc
aaccaagataagaagaacatgcttttttctggtacaaacattgctgctgggaaagtcatg
ggagtggtggtggcaactggagttaacactgaaattggcaagatccgagatgagatggtg
gccacggaacaagagagaacaccgcttcagcagaaactggatgaatttggggagcagctt
tccaaagtcatctcgctcatttgcattgcagtctggatcataaacattgggcactttaat
gatccagtgcacgggggctcctggatccgaggtgctatctactactttaagattgcagtg
gcactggctgttgcagccatccctgagggtctacctgctgtcatcaccacctgcctggcc
ctcggaactcgaagaatggcaaagaaaaatgccattgttcgaagtcttccgtctgtggaa
acccttgggtgtacttctgttatctgttcggacaagactggtacacttactacgaaccaa
atgtcagtctgcaggatgttcattctggacaaagttgaaggtgatacttgttcccttaat
gagttcaccataactggctcaacatatgcacccatgggagaagtgcataaagacgataag
ccaataaaatgtcatcaatatgatggtcttgtagaattagcaaccatttgtgctctgtgt
aatgactctgctttggattacaatgaggcaaaaggtgtgtatgaaaaagttggagaagct
acagagactgctctcacttgcctggttgagaagatgaatgtatttgatactgaactgaag
ggtctttctaaaatagaacgtgcaaatgtctgcaactcggtcattaaacagctgatgaaa
aaggagttcactttagagttctcacgggacaggaagtcaatgtctgtgtactgcacgcca
aacaagccaagccggacgtccatgagcaagatgttcgtgaagggcgctccagaaggtgtc
atcgacaggtgtacccacattcgagttgggagtaccaaggtccttatgacccctggagtc
aaacagaagatcatgtccgtcattcgggagtggggcagcggcagtgacaccctgcggtgc
ctggccctggccactcacgacaacccactgcgcagagaagagatgcatctggaggactct
gccaacttcatcaagtatgagacaaacctgaccttcgtcggctgtgtgggcatgctggac
cctcccaggatcgaagtggcctcgtcggtgaagctgtgtcgccaggcaggcatccgtgtt
atcatgatcacaggggacaacaagggcaccgccgtggccatctgtcgccgcattggtatt
tttggccaggatgaagatgtgacatcaaaggctttcacaggtcgggagtttgatgaactc
agtccctcagctcagagggatgcctgcttgaatgcccgctgctttgcccgagtcgagccc
tcccacaagtctaagattgtggagttcctacagtcctttgatgagatcacggccatgact
ggcgatggtgtgaatgatgctcctgctctgaagaaggctgagattggcattgccatgggc
tctggcactgcggtggctaagaccgcctctgagatggtcctggccgatgacaacttctcc
accatcgtggctgctgtggaggaagggcgggccatttacaacaacatgaagcagttcatc
cgctacctcatctcgtccaacgtgggggaggtggtctgcattttcctgacagcagcgctt
gggtttcctgaggctttaattcctgtccagctgctctgggtcaatttggtcacagatggc
ctgcctgccactgcactggggttcaaccctcctgacctagacatcatgaataaaccaccc
cggaacccgaaggaaccactgatcagcgggtggctctttttccgttacctggctattggc
tgttatgttggtgccgctactgtgggtgctgctgcatggtggttcatcgctgccgacggg
gggcccagagtgtccttctaccagctgagtcatttcttacaatgtaaagaggacaatccg
gactttgaaggagtggattgtgcggtcttcgagtccccatacccaatgacgatggcactc
tctgtcctagtgaccatagagatgtgtaacgccctcaacagcctgtctgagaaccagtcc
ttgttgaggatgcctccttgggagaacatctggctcgtgggatccatctgcctgtccatg
tccctccactttctgatcctctacgtggagcccttgccactcatcttccagatcacaccg
ctgaacctgacccagtggctgatggtgctgaagatctccctgcctgtgattctcatggat
gagacgctcaagtttgtggcccgcaactacctagagcctgccatactggagtaa
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