Cavia porcellus (domestic guinea pig): 100713551 Help Entry 100713551         CDS       T07777                                  Symbol Syne1 Name (RefSeq) nesprin-1 isoform X9   KO K19326   nesprin-1 Organism cpoc  Cavia porcellus (domestic guinea pig) Pathway cpoc04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:cpoc00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     100713551 (Syne1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:cpoc03036]     100713551 (Syne1) Chromosome and associated proteins [BR:cpoc03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     100713551 (Syne1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Spectrin SYNE1 Spectrin_SYNE1 KASH STIV_B116-like Motif Other DBs NCBI-GeneID:  100713551 NCBI-ProteinID:  XP_013006515 Ensembl:  ENSCPOG00000039266 LinkDB All DBs Position Unknown AA seq 6443 aa AA seqDB search MTGLIKKHEAVSQLCFKTQASLQESLEKHFNDSMQEFQEWFSGAKAAAKESSHRTGDSKV LETKLHDLQNILDSVSDGQSKLDAVTQEGQTLYAHLSKQMVGSIQEQITKANEEFQAFLK QCLKDKQALQDCASELGSFEDQHRKLNLWIHEMEERLNTENLGESKQHLPEKKNEVHKVE MFLGELLAARESLDKLSQRGQLLSEEGHGPGQGGRLGSQLLTSYQNLLRMTKERLRGCQL ALQEHEALEEALQDMWSQVREVQDRLACAESTLGSKETLERRLSQIQDILLMKGEGEVKL NMAIGKGEQAIRSSSKEGQKAIQAQLQTLKNTWADVVSTSVHAQSTLESVLSQWNDYLER KHQLEQWMESVDEKLEHPLQLQPGLKEKFSLLDHFQAIMSEADDHTGALYRLCAKSRELY EKTQDESFKETAQEELKTQFHDIVTVAKEKMRKVEEIVKDHLMYLDAVHEFTDWLHSAKE ELQRWSDMSGDSSATQKKLLKIKELIDSRELGAGRLARVESLAPGVKQHTAASGCELLHT EMQALRADWKQWEDSIFRTQSSLEDLVSQMALSEQEFSGQVAQLEQALGQFGALLKTWTQ QLALLEGKNTDTELVESWHAGQEILDALQKAEPTTEDLKSQLNELCRFSRDLSTYSGKVS GLIKEYNCLCLQASKGCQSKEQILQQRFRKAFRDFQQWLVNAKITTAKCFDIPQNITEVS ASLQKIQEFLSESENGQHKLNTMLSKGELLTSLLTKEKAKSIQAKVEAAKEDWKNFHSNL HQKESALENLKIQMKDFEVSADPVQNWLSKTEKLVHESSNRLYDLPAKRREQQKLQSVLE EIHCYEHQLNRLKEKAQQLWEGQAASKSFMHRVSQLSAQYLALSNSTKEKVSRLDRIVAE HNQFSLGIKELQDWMTDAVHTLDSYCHPTSDKSVLDSRILKLEALLSVKQEKEIQMKMIV TRGEYVLQNTSPEGIPAIQQQLQGVKDMWASLLSAAIRCKSQLEGALSKWTSYQDDVRQF SGWMDSVEANLSDSERQCAELREKVTALGKAKLLNEEVLSHRSLLETIEVKGASMTEHYV TQLELQDLQERYLAIRERAKEAVTKSEKLVRLHQEYQRDLKTFEVWLGQEQEKLDQYSVL EGDAHIHETTLRDLQELQMRCAEGQALLNSVLHTREDVIVSGIPLAEDRVLESLRQDWQA YQHQLSETRTQFNNIVNKLRLMEQKFQEVDEWLKKTEEKVSLRTGRQSNRAAKEMQLHQM KKWREEVTAHKDEVEEVGAKAQEILDESHVNSRMGCQATQLTSRYQALLLQVLEQIKFLE EEIQSLEESELSLSSYSDWYSSTHKNFKNVATKIEKVDKKVMEKKLKTLEVLLKDMDKGH SLLKSAREKGEKAAKYLEEGEAEMLRKDIHDQVEKLEELTGTMRKEHVTVEKGLHLAKEF SDKCKALTRWIAEYQEILQVPEEPKMELYEKKAQLSKYKSLQQTVLSHEPAVNSVREKGE ALLDLIQDVTLKDKIDKLQRDYQDLCSMGKEHVLCLEAKVKDHEDYNSELQEVEKWLLQM SGRLVAPDLLETSSLETITQQLAHHKAMMEEIAGFEDRLNDLKVKGDTLLGQCADHLQEK LKQSVRAHLQGTRDSYSAICSTAQRVYQSLEHELQKHVSRQDTLQQCQAWLSTVQPDLKP SPQPPLSRAEAVKQVKHFRALQEQARTYLDLLCSMCDLSNSSVKTTAKDIQQTEQMIEQR LAQAQNLTQGWEEIKHLKAELWIYLQDADQQLQNMKRRHSELELNIAQNMVAQVKDFAKQ LQCKQASMSTILEKVNKLTKKQESPEHKEISHLNDQWLDLCLQSDKLCSQREQDLQRTRE YHDRMNVVEAFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQDRKYAIEDLKDQKQK MIEHLNLDDKELVKEQTSHFEQRWFQLESLVKGKIQVSVTNLEELNVVQSKFQELMEWAE EQQPNIAEALKQSPPPDMVQSLLMDHLAICSELEAKQLLLKSLTKDADRVMADLGLNERK VIQKVLCDAQRHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREH ICLLPDDVSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKGVTEQEKGEVLGKLQELQS VYDSVLQKCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELDTQ LDKYQHILEQSPEYENLLLTLQRTGQAMLPSLNEVDHSYLSEKLNALPQQFNVIVALAKD KFYKVQETMLARKEYASLIALTTQALSELEDQFLKMRKVPTDLAVDEAVSLQDNCKALLG EVVALGEAVDELNQKKESFRSTGQPWQPDKMLHLVTLYHRLKRQAEQRVGLLEDTTSSYK EHLKMCQQLKSQLEAVKMEQSKVNEETLPAEEKLKMYHSLAGSLQDSGILLKRVALHVED IALLLDPSAYEKAKHQVQEWQEELTLLTSSIGEMVTECEGRMVQSRDFQTEMSHSLDWLR RVKAELSGPICLDLSLQDIQQEIRKIQIQQEEVQSSLRIMSALSNKEKEKFTKAKELISA DLEHTLAELAELDGDIQEALRARQATLTEIYSQCQRYYQVFQAANDWLEDAQEMLQLAGN GLDVESAEENLKSHKEFFSTEDQFHSNLEELQALVTRLDPLIKSTGREDLTQKMTSLEER SQRITQDSCAQLDLLQRCTVQWQDYQKAREEVIELMNDAEKKLSAFSLLKTSSSHEAEEK LSQHKALVSEVDSFHDKVVALEEKASQLEKSGNDASKATLNRSTTTVWQRWTRLRAVAQD QEKILEDAVDEWKGLNNKIKKATEIIDQLQDKLPGSSAEKASKAELLSLLEYHDTCVLEL DQQQLALGVLQQQALSMLQDGALPSGEEPPTLQEITAMQDRCLNMQEKVKSNGKLVRQEL QEREVVETQINSVKSWVQETKEYLGNPTIEVDAQLQELQILLTEATNHRQNIEKLAEEQK NKYLGLCTIVPSEISLQLAEVALDLKIYDQIQEKVKEIEQSKTMSQEFSRQIQQVAKDLT TILTKLKAKTDNLVQAKTDQKVLGEELDGCNSRLMELDAAVQKFSEQHSHLSKPLAKKIG KLTELQQQTVRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLVHGNIAWNSANQL REQYISHQALLEESEEIYSDLEAMSEKLQCLTSVYYTEKMSQQVTELGRETEELRQVIKI RMQSLQDAAKDMKKFEAELKNLQMALEQAQTTLTSPEIGRLSLKEQLSHRQHLLSEMESL KPKVQAVQLCQSALRIPEDVVASLPLCHAALHLQEEASRLQHSAIQQCNLMQEAVVQYEQ YEQEMKHLQQLIESAHREIEDKPVATSNIQELQAQITRHEELAQKIKGYQEQIASLNSKC KMLTMKAKHATMLLTVTEVEGLAEGTEDLDRELLPTPSAHPSVVMMTAGRCHTLLSPVTE ESGEEGTNSEISSPPACRSPSPVANTEASVNQDIAYYQALSAERLQTDAARIHPSTSASQ EFYEPGLEPSATAKLGDLQRSWETLKNVISEKQRTLYEALERQQRYQDSLQSISTKMETI EMKLSESLKPGRSPESQMAEHQSSLQALMDEILMVQDEINALQASLAEEMVFEARESDPA EQLALQSTLTVLAERMSTIRMKAAGKRQLLEEKLNDQLEEQRHKQALQRYLCEADELDHW LLSTKANLDVALGAPTEPMDMEAQLVDCQNMLVEIEQKVVALSELSLHNENLLLEGKAHT KDEAEHLAGKLRTLKGSLLELQRALRDRQLHIQQGTSQEKEESDADPTAAQSPGLQEWLA QVRTTRTHQRQNSLQQQKELEQELAEQKSLLQSVASRGEEILTQHSAAEAASGLGEKPDV LSQELGQEGEKSTAEDQMRMKWESLHQEFSTKQKLLQSVLEQEQEQVLYSRPNRLLSGVP LYKGEGQTQDKSAVTSLLDGLNQAFEEVSSQDAGAKNQNMHLEQKLYDGVSATSTWLDDV EERLFVATALLPEETETCLFNQEALAKDIKEMSEEVDKNKNLFSQTFPENGDNRDVIEDT LECLLGRLSLLDSVVDQRCHQMKERLQQILSFQNDMKVLFSSLADNKYIILQKLANVFEQ PVAEQIEAIQQAEEGLKELDAGITELKRRGDKLQIEQPSLQELSKLQDMYDELVMTIGSR RSGLNQNLVLKSQYERALQDLADLLETGGEKMAGDQKIIVSSKEEIQQLLDKHKEYFQGL ESHMILTEMLFRKIISFAVPKETQCHADLMAQASTVLKRAHKRGVELEYILETWSRLDED LQELSRQLEVVENSIPSVGLVEESEDRLIERTSLYQHLKSSLNEYQPKLYQVLEDGKRLL ISVSCSDLESQLNHLGENWLSNTNKVSKELHRLETILKHWTRYQSESADLIHWLQSAKDR LVFWTQQSVTVPQELEMVRDHLNAFLEFSKEVDAKSALKSSVLSTGNQLLRLKKVDTAPL RSELSHIDSQWMDILTNIPAIQEKLHQLQMDKLPSRHAISEVMSWISLMESVIQKDEEDI KNAIGYKAIHEYLQKYKGFKIDINCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLG AMNKSWQILQGLVTEKIQLLEGLLESWSEYENNVQCLKTWFETQEERLKQQHQIGDQASV QNALKDCQDLEDLIKAKEKEVEKIEQNGLALIQNKKEEVSATVLCTLQELNRTWANLEHM AGQLKIRLKSVLDQWDQHKVALEEMNSHLMEARYSLSRFRLLTGSFEAVQVQVDNLQNLH DDLEKQERSLEKFGAVTNQLLKECHPPVTETLTNTLKDINMRWNNLLEEIAEQLHWSKAL LQLWQRFKDYSSQCASTVQQQEERTNELLKAATNKDIADNEVATWIQDCNDLRKGLGTIK DSLFILHELGEQLKQQVDASAAEAIQSDQLSLSQHLCTLEQALCKQQTMLQAGVVDFETF AKSLEALEAWIVEAEEVLQGQDPTHSSDLSTIQERMEELKGQMLKFSSMAPDLDRLNELG YRLPLNDKEIKRMQNLNCLWSLTSSQTTERFSKLQSFLLQHQTFLEKCETWMEFLIQTEQ KLAVEISGNYQHLLEQQRAHELFQAEMFSRQQILHSIIIDGQRLLEQGQVDDRDEFNLKL TLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYRAMAEKLRKWLVEVSYLPMNGLGSVPVPL QQVRTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSTDSAAEAALQAELTEIQEKWKSA SLHLEEQKKKLAFLLKDWEKCEKGVADSLEKLKNFKRKLSQPLPDHHEELHAEQMRCKEL ENAVGSWTDDLTELTLLRGTLAAYISADDISILNERIELLQRQWEELCHQVSLRRQQVGE RLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIEEMIEKLKKDYQEEIAVAQENKIQLQ QMGERLAKASHETKASEIEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSNL RTWLAHIESELAKPIAYDSCDSEEIQRKLNEQQELQKDIEKHSTGVASVLNLCEVLLHDC DACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKI SERTAAFPSSSGVLYTVAKEELKKFEAFQRQVHETLTQLELINKQYRRLARENRTDSACS LKQMVHDGNQRWDNLQKRVTSILRRLKHFISQREEFETARDSILVWLTEMDLQLTNIEHF SECDVQAKIKQLKAFQQEISLNHSKIEQIIAQGEQLIEKSEPLDAAVIEEELDELRRYCQ EVFGRVERYHKKLIRLPLPDDEHDLSDRELELDDSAALSDLHWQDSSVDGVLSPQPSSNP SLSLPQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAVSRTLQSEDEEGQEEKDFY LRGAVGLSDVVIPESPEAYVKLTENAIRNTSGHHSALESQIQQLDKALDDSRFQLQQTEN VLRSRTPTGPELDSSYKGYMKLLGECSGSIDSVRKLEHKLKEEEENFPGFVNLNSTEMQT AGVIDRWELLQAQALSKELRMKQNLQKWQQFNADLNNIWTWLGETEEELERLQRLELSTD IQTIEHQIKKLKELQKAVDHRKAIILSINLCSSEFTQADSKESQDLRDRLSQMNGRWDRV CSLLEDWRALLQDALMQCQDFHEMSHGLLLMLENIDRRKNEIIPIDSHLDTEILQDYHKQ LMQIRRELSESQLKVTSLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIK DLEKLLDMSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNKQKPPRGKCSVSQPGPSVSS PNSRSTKGGSDSSLSELRPARSGRAFLFRVLRAAFPLQLLLLLLVGLACLVPMSEEDYSC ALSNNFARSFHPMLRYTNGPPPL NT seq 19332 nt NT seq  +upstreamnt  +downstreamnt atgacaggcctgataaagaagcatgaagctgtgagccagctgtgtttcaaaactcaggcc agcctgcaggagtctctggaaaaacatttcaatgattctatgcaggaattccaagaatgg ttttcgggagcaaaagcagcagccaaagaatcatcgcatcgaactggtgacagtaaagtt ctagagacaaagctccatgatctccagaacattctggactcagtcagtgatgggcaaagc aaacttgatgcagtgactcaggagggacagactctgtatgcacatctatctaagcaaatg gtcggtagcattcaggagcaaattaccaaggcgaatgaagagtttcaggcatttctgaag cagtgccttaaagacaagcaggctctccaagactgtgcttctgagctagggagctttgaa gatcagcacagaaagctgaacttatggatccatgaaatggaagaaagattaaatacagaa aatttaggagagagtaagcagcatctgcctgaaaagaaaaatgaagttcataaagttgaa atgtttctgggagaacttctggcagctagagagtcacttgataaactttcccagagaggg cagcttctcagtgaagaaggtcatggtccagggcagggtggtcgcttgggctcccagctc ctcaccagctaccagaacctactcagaatgaccaaggagagactgaggggctgccagctt gccctccaggagcacgaggcactagaggaagcactccaggacatgtggtcccaagtgaga gaagtccaagacagactggcctgtgcagaaagcacacttgggagcaaggagaccttggag aggcgactgtcacagatacaggatattctcttgatgaaaggtgaaggagaggtcaagttg aacatggccattggcaaaggggaacaggccattagaagcagcagcaaagaaggtcagaag gcaattcaagcacagttgcagacccttaagaacacgtgggccgatgttgtgagcacctct gtgcatgctcagagcactctagagtctgtgcttagccagtggaatgactaccttgaaagg aaacaccagctggagcagtggatggaatcagtggatgaaaaactagaacatcctttacag ctgcagccaggcctgaaggagaagttttccctgctagaccattttcaggccatcatgtct gaggcagatgatcacacgggagctctgtaccgcctgtgcgccaagtccagggagctctat gagaagactcaggatgagtcctttaaggaaacagctcaagaggaactgaagacacagttc catgatatcgtgactgtggccaaggaaaaaatgaggaaagtggaagagattgtgaaggac catctcatgtatttagacgcagtccatgaattcactgattggctccattcagcaaaggaa gaactccagaggtggtcagatatgtctggggattcatcggccacccagaaaaagttgcta aaaatcaaggagctgatagattccagagagctaggagcaggccgcctggcccgagtggaa tcgctggcccccggagtgaagcagcacacagctgccagtgggtgtgagctcctgcacacg gagatgcaggccctgcgcgccgactggaagcagtgggaagacagcatattccgaacacag agcagcctggaggacctggtcagtcagatggccctttcggagcaggagttctcaggccaa gtggcccagctcgagcaggccctgggacaattcggtgcccttctgaaaacctggactcag cagctggccctcctggaaggcaagaacacggatactgagttagtggaatcctggcacgca gggcaagagatcttggatgcactacaaaaagcagagcctacaacagaggatctcaagtct cagctgaatgaactttgtcgattttctagagacctgagtacatacagtggaaaagtttct ggcttgattaaagaatataattgtctctgtttgcaagcatccaagggctgccagagtaaa gaacagattttacagcaaagatttcgaaaagccttcagggattttcagcagtggttggtt aatgcaaaaatcactactgccaaatgttttgatatacctcaaaatattactgaagtttcc gcaagtctgcagaaaatacaggagtttttgtcagaaagtgaaaatgggcagcataaacta aacacaatgctttccaaaggagaacttctgacttctctgttgaccaaagagaaagcaaaa agtatccaggccaaagttgaagctgcaaaagaagattggaaaaatttccattcaaatctc caccagaaggaatctgccctagaaaatctaaagatccagatgaaagactttgaagtaagc gctgatccagtgcagaactggctgagcaaaactgagaagctggtgcacgaaagcagcaac cgcctctatgatctgccagcaaagcggagagagcagcagaagctgcagtctgtccttgag gaaattcactgctacgagcatcagctcaacaggctgaaagagaaagctcagcagctgtgg gaaggacaagctgccagcaagagctttatgcacagagtgtcacagctgtctgctcagtat ctagcgctaagcaattcaaccaaggagaaagtatccagactggacagaatcgttgcagag cataatcagttctcccttgggattaaagaattacaagactggatgacggatgcagttcac acattggactcttactgccacccaacatccgacaaaagtgtgctggacagcaggatactc aagctagaggcgctgttatcagtgaaacaggaaaaagagatacagatgaaaatgatagtc accaggggggagtatgtgctgcagaacacctctccggaaggcattcctgcaattcagcag cagctgcagggtgtgaaggacatgtgggcatccctcctgtctgcagccattcgctgtaaa agtcaactcgaaggagcgctttcgaagtggacaagctatcaggacgatgttcgacagttc tctggttggatggacagcgtagaagccaacctaagtgactccgaaaggcaatgtgcagag ctgcgggagaaagtaaccgctctcgggaaagccaagctgttaaatgaagaagtgctaagt caccgtagtctgctggagaccattgaagtcaaaggagccagcatgacggagcactatgtc acccagctagagctccaggatctgcaggagcgatacctagcaatcagagagagggccaag gaagcagtaaccaaatctgaaaaacttgttcgtctgcaccaagagtaccagagagatcta aagacctttgaagtttggctgggacaagaacaagaaaaacttgaccaatactcagttctt gaaggtgatgcccacattcatgaaacaacactgagggaccttcaggagctccaaatgcgt tgtgcagagggacaggcactgttgaactcggtgctgcataccagagaggacgtgattgtg tcaggcatccccctggcggaggaccgggtgttggagtctctccggcaggactggcaggct taccagcaccaactctctgagactcggacacaattcaacaacatagtgaacaagctgagg ttgatggagcagaaatttcaggaagtagatgaatggcttaaaaaaacagaggagaaagtt agtctcagaacaggacgccagtctaaccgggcagccaaggagatgcagttacatcagatg aagaaatggcgtgaagaagtgactgcacataaagatgaagtcgaggaggtgggagctaaa gcccaggagatactggatgagagccacgtgaacagcagaatgggctgccaggccacccag ctgacctccagataccaggccctgctcctccaagtgctggaacaaatcaaattcctggaa gaagagattcagagtttggaagaatcagaattatctctcagttcctattctgattggtat agctctactcataaaaattttaagaatgtggctaccaaaattgagaaagtagataaaaaa gtgatggagaaaaaattgaagacattagaggttttgttaaaagacatggataaaggccac agtttgttgaagtcagcccgggaaaaaggagagaaggcagctaagtacttggaggaaggc gaggcagagatgctaagaaaagacatccatgatcaggtggagaagcttgaggaactgacc ggcaccatgagaaaagagcacgtgactgtggaaaaaggtcttcatttagcaaaagaattc tcagataaatgtaaagcgctgactcgttggatagcagaataccaggaaattctacaggtt cctgaagaacccaaaatggaattatacgagaagaaagctcagttatctaagtacaagtca ttgcagcaaactgtactgtctcatgaaccagcagtcaactcagtgagagagaaaggtgaa gctcttctggatttgatccaagatgttactttaaaggacaaaatagacaaacttcagaga gattaccaggacctctgcagcatgggaaaggaacatgtcctctgcctggaggcaaaagtt aaagaccatgaagactataacagtgagctccaagaagtggagaagtggctgctgcagatg tctgggaggctggtggcacctgaccttctggagacgagcagcctggagacaattactcag cagctggcccatcacaaggccatgatggaagaaattgctggttttgaagaccgtttgaac gacctgaaagttaaaggtgacactctgcttggccagtgtgcagatcacctgcaagagaaa ctgaaacagagtgtgcgtgcccaccttcagggcacaagggacagttactcagcaatctgc agcacagcccagcgcgtgtaccagagtctggagcatgaacttcagaagcatgtcagccgg caagataccctgcagcagtgccaggcctggctttccacggtccagccagacctaaagcca agtccacagccacctcttagccgggcagaagccgtcaagcaggtcaaacactttagagct ttgcaggagcaagcaaggacttacttggatctcctttgttccatgtgtgacttgtccaac tcttcggtaaaaaccacagcaaaagacattcagcaaacagaacaaatgatcgaacaaagg ctcgctcaggcacagaacttaactcagggctgggaagagatcaagcacctaaaggctgag ctgtggatttaccttcaggacgccgatcagcaactacagaacatgaagaggaggcactct gaactggagctaaacatcgcccagaacatggtagcccaagtcaaggattttgctaaacaa ctgcagtgcaaacaggcatccatgagcaccatcttagaaaaagtgaataagttaacaaag aagcaggaatctcctgagcacaaggagataagtcacttaaatgaccagtggctggatctg tgccttcagtcggacaaactgtgttctcaaagagaacaggaccttcagagaacaagagag tatcatgaccgtatgaatgttgtggaagcattcttagaaaaattcactacagaatgggat aacctggccagatctgatgcagagagcacagctgtccacttggaagctttgaaaaagctg gccttggccttgcaagacagaaagtatgccattgaagatctgaaagatcaaaagcaaaaa atgatagaacatctgaatctagatgacaaagaattagtcaaagaacagacaagtcacttt gaacaacgctggtttcagctcgagagcctcgttaaagggaaaattcaagtgtcagtcact aacttggaggagctcaatgtggtgcagtccaaatttcaggagctaatggagtgggcagaa gaacaacaacccaacattgctgaggctctcaagcagagtcccccgcctgatatggtacag agcctcctcatggatcacctggccatctgcagtgagctggaagccaaacagttacttctg aagtcgctcacgaaggatgccgacagggttatggctgatcttggcctcaatgagaggaag gtgatccagaaggtcctctgtgacgcacaaaggcatgtgaactgtctcagtgacttagtg ggccagaggaggaagtacttaaacaaagcactatctgagaaaactcagtttctcatggca gtatttcaggcaactagccaaattcaacagcatgagcgaaagatcatgttccgcgaacac atctgcctgttaccagatgatgtgagcaagcaagttaaaacgtgtaagagtgcacaagcc agtctcaagacgtatcagaatgaagtcactggactttgggcccagggtcgtgaattaatg aaaggagtcacagagcaggaaaagggtgaggttctgggtaagcttcaggaattgcagagt gtttatgacagtgttttacaaaagtgcagtcatcggttacaagaactagagaagaatcta gtttctcgaaagcattttaaggaagattttgataaagcttgtcattggctcaaacaagca gatattgttacatttcctgaaattaacctcatgaatgagagtactgagcttgatacacaa ctggacaaataccaacacattcttgaacaatctccagagtatgaaaatctgctacttact ctccaaagaactgggcaggccatgttaccctccctgaatgaagtcgatcattcctacctc agtgaaaagctaaatgctctgccacaacaatttaatgtcattgtcgccttagctaaagac aagttctataaagtgcaagaaacaatgctggctcgaaaagagtatgcttctttgattgca ttgacaacacaggctctgagtgaactcgaagatcagtttttaaagatgagaaaagttccc acagacctggctgttgatgaggctgtgtctcttcaggacaactgcaaggccctgctgggt gaggtggtggctctcggggaagcagtagatgagctcaatcagaaaaaagaaagttttcgc agcacaggtcaaccttggcagccagacaagatgctgcaccttgtcaccttgtatcacagg ctgaagagacaggcagaacaaagggtaggcttattagaagacaccacgagctcttataag gagcatctaaagatgtgccaacagctaaagagtcaactagaggctgtgaaaatggagcag tccaaagtgaatgaggagactctgcccgcagaggagaagctcaaaatgtatcactcctta gctgggagcctgcaggactcaggaattctgctaaaacgagtggccctgcatgtggaggat attgctctgctcctggacccctcggcttatgagaaagccaagcatcaggtccaggaatgg caagaggaactgacactgttgacttctagcattggcgagatggtaacagagtgtgagggc cgaatggtacagagcagagacttccagacagagatgagccactccctagactggttgcgg agggtgaaggccgagctcagtgggcccatatgcctggacctcagtctccaggatatccag caggaaatccgcaagattcagatccagcaggaggaggtccagtccagcctgagaatcatg agcgccctgagtaacaaggagaaggagaaattcacgaaagctaaggagctgatttctgct gacttagaacacacacttgctgagctcgcagagctggatggagacattcaggaagctttg cgtgcccgacaggctaccttgactgaaatatatagtcagtgtcaaaggtattatcaagtt tttcaagcagctaatgattggcttgaagatgcccaagaaatgttacagctggcaggcaat ggcctagatgtggagagtgcagaggaaaatctcaaaagccacaaggaatttttcagtacc gaggatcaatttcacagtaatctggaggaactccaagcactagtgaccaggttggaccca ctcatcaagtcaactggcagagaagacctcacacagaagatgacttccctggaagagagg agccagaggatcacccaggactcctgtgcccagttagacctcttgcagagatgcacagtg cagtggcaagattatcagaaagcgagggaagaggttattgaattgatgaatgatgctgaa aagaaattgtctgcattttctttgttgaagacatcttccagtcacgaagcagaagaaaaa ttgtcacaacataaggcattagtgtcggaggttgactctttccatgacaaagttgtggcc ctagaggaaaaagcttcacaactggaaaaatctggaaatgatgcgagcaaagccacacta aacaggtcgacaactactgtctggcagcgctggacgcgtctgcgcgctgtggcccaggac caggagaagatcctggaagacgcagtggatgagtggaagggtttgaacaataagattaaa aaagccactgaaatcattgatcaactgcaagacaagttacctggaagttcagcagaaaaa gcctccaaagcagaactattgtcccttcttgagtaccatgatacttgtgtgctagagctg gaccagcaacagctggctttgggcgtgctgcagcagcaagcactgagcatgcttcaggat ggagccctcccctctggagaagagccacccaccctgcaggaaatcacagctatgcaagat cggtgcctcaacatgcaagagaaagtgaagagtaacggaaagttggtgagacaagagttg caagagcgagaagtggtggagactcagattaattctgtgaaatcatgggttcaagagaca aaggagtatttagggaacccaacaattgaagtagacgctcaacttcaagaactgcagatc ctcctgacagaagccacaaatcacagacagaacattgagaaactagctgaagaacagaag aataagtacttaggcctttgtactatagtgccttctgaaatctctcttcagttagcagaa gtggcattggacctgaagatttatgaccagatccaagaaaaagtaaaagaaattgagcag agcaagaccatgagtcaggaattcagccggcaaattcagcaggtagccaaagatctcact acgattttaacgaagctgaaagcaaaaacggataatctagttcaagctaaaactgaccaa aaggtcctgggagaggaactagatggctgtaattcacggttaatggaattagacgcagcg gtacaaaagttctcagaacagcatagtcacctgagcaagccactggccaagaagatagga aaactgaccgagcttcagcagcagactgtccggcaagctgagaatcggctctccaaactc aatcaggcagcatcacatttggaagaatacaatgaaatgcttgagctaattttgaaatgg attgagaaagctaaagtcttggtacatggaaacattgcgtggaattctgcgaaccagctt cgggaacagtacatttcacatcaggccctgctagaagaatctgaagaaatttacagtgat ctggaagcaatgtctgagaaattacagtgcctcacgagtgtgtactatacagaaaagatg tctcagcaagtgacagaactgggacgagagactgaggagttacggcaggtgataaaaatt cgtatgcagagcctccaagatgcagccaaggatatgaaaaaattcgaagcagagctgaaa aacttacaaatggctttggaacaagctcaaaccaccctgacttctccagaaattgggcgc ctgagtctcaaagagcaactatcacatcgacagcatttgctgtctgagatggagtcattg aagccaaaggtgcaagccgtgcagctctgccagagcgctctgcggatccccgaggatgtg gtggccagcttgccactctgccacgccgccctgcacctgcaggaggaggccagccggctg cagcactccgccatccagcagtgcaacctcatgcaggaggcagtggtccagtacgaacag tatgagcaagagatgaagcacctccagcagcttatagaaagtgcacacagagagatcgag gacaaacctgtggccaccagcaacatccaggagctgcaagcccagataacacggcacgag gagctggcgcagaaaatcaagggctaccaggagcagattgcctctttgaattccaaatgc aagatgctgacaatgaaagccaagcacgccaccatgctgctgacggtgacagaggtcgag gggctggcagaaggcaccgaggatctggatagagagctcctccccacaccgtcggcccac ccctctgtggttatgatgactgcaggtcgctgtcacactttgctgtcacctgtcactgag gagtctggggaagagggaaccaacagtgagatttcttctccacctgcttgtcgctcccct tcacctgtggctaatacagaggcttctgttaaccaggacattgcttattaccaagccttg tctgctgagaggctgcagacagatgctgccaggatccaccccagcacatcagcatcccag gagttctatgagccaggactggagccatctgctactgccaaactgggtgatttgcagcgt tcttgggaaactttaaaaaacgtgatcagtgaaaagcagcgcacgctgtatgaggctttg gaacgccagcagaggtaccaggactctctccagtccatctcgacaaaaatggagaccatt gagatgaagcttagtgagagcctcaagcccggcaggagtccggaaagccagatggccgaa catcagtcttccctgcaggcgctgatggacgagatcctcatggtccaggacgaaatcaac gcgctgcaggcctccctggcagaggagatggtgttcgaggcgcgggagtcagaccctgca gagcagctggccctgcagtccacactcacggtgctggccgagcgcatgtccaccatccgg atgaaggctgcgggcaaacgacagctgctggaggagaagttaaacgatcagttggaggaa cagaggcacaagcaggctctgcagcggtacctctgcgaagccgatgaactggatcactgg ctcttgagcacaaaggccaatctggatgtcgccctcggtgcgcccacggagccaatggac atggaggcccagctggtggactgccagaacatgctggtggagatcgagcagaaggtggtg gccctgtctgagctgtccctccacaacgagaatctgctgctggagggcaaggcacacacg aaggatgaggccgagcatctggccgggaagctgaggacgctcaaagggagcctcctggag ctgcagagagcccttcgagacagacagctgcacatccagcagggaacttcacaagagaag gaggaaagcgatgctgaccccacggccgctcagagccctggtctgcaggaatggttggct caagttcgcaccactcggacccaccagcggcaaaacagtctccaacagcaaaaagaatta gagcaggaattagctgagcagaagagccttctccagtcagtagccagccgtggagaggag attctaacccaacattcagctgcagaagccgccagtggccttggtgaaaaacctgatgtg ttatcccaggagttgggacaagaaggggagaaatcaactgcagaagaccagatgagaatg aaatgggaaagcctacatcaagaatttagtaccaaacagaagctactacagagtgttctg gaacaagaacaagagcaagtgctatacagtagaccaaatcggcttctgtctggtgtgcca ctgtacaaaggcgaaggacagacccaggataaatccgcagtgacgtcattactggatgga ctgaaccaggcctttgaggaggtttcatcccaggatgctggagcaaagaatcaaaatatg cacttggaacagaagctctatgatggtgtctcagctacctccacttggttggatgatgtt gaagagcggttatttgttgccacagcacttttaccagaagaaacagaaacttgtctcttt aaccaggaggctcttgccaaagacattaaggaaatgtctgaagaagtggataagaacaag aacttgttttcccaaacttttccagagaatggtgataaccgagatgttattgaagatact ttggagtgtcttttgggcagattatccctactggactcagtagtggatcagcggtgccat cagatgaaagaaagactccagcaaatactaagtttccagaatgacatgaaggtgctgttt tcctcactggctgacaacaaatacatcattcttcagaaactggcgaatgtgtttgaacag cctgtagcagaacagatcgaggcaatacagcaggctgaagagggactaaaggaactggat gcaggaatcacagaattaaaaagacgtggtgacaagctgcagattgagcagccttccctg caagaactctccaagctccaggacatgtatgatgaactggtgatgaccattggctcacga aggagtggtctgaatcaaaatcttgtactcaagagtcagtacgaacgggctctgcaggat ctggcagacctgctagaaactggaggagagaagatggcaggagatcagaaaatcattgtg tcttccaaagaagaaattcaacaattactcgacaaacataaggaatactttcagggtctg gaatctcatatgatcttgacagaaatgctcttcagaaagatcatcagctttgcagtccca aaggaaacccagtgccatgcggacctgatggctcaggcatctactgtgctgaagcgggca cacaagaggggtgtggagctggagtacatcttagagacttggtcccgtctagatgaggac ctgcaggagctcagcagacagctggaggtggtggaaaacagcatcccaagtgtgggtctg gtggaggagagtgaggacaggctcatcgaacggaccagcctctaccagcatttaaaatcc agcctcaatgaataccagcccaaattatatcaagtattagaagatggaaaacgactgctg atatcagtcagctgctcagatctagaaagccagctaaatcaccttggagagaactggcta agtaataccaataaagtgtctaaggaacttcacagattggagacaatattgaaacactgg accagatatcaaagtgagtctgcagatctaattcactggttacagtctgcaaaagacagg ctggtattttggactcagcaatctgtgacagtcccacaagaactagaaatggtccgtgat catctaaatgctttcctggaattttctaaagaagtggatgctaaatctgccctcaaatca tctgttctgagcactggaaatcagcttctccgattgaagaaggtggacacagctcccctg cgttctgagttgtcccacattgacagccagtggatggacatcctgactaatattccagct atccaggaaaagctccaccagctccaaatggacaagctgccttcccgccatgccatttct gaagtcatgagttggatctctttaatggaaagtgttattcagaaggatgaagaagatata aaaaatgccataggttacaaagcaattcatgaataccttcagaaatacaagggttttaaa atagatattaactgtaaacagctaacagtcgattttgtgaaccagtctgtgctacaaatc agcagccaggatgtggaaagtaaacggagtgataagaccgattttgctgagcaacttgga gcaatgaataaaagttggcaaattctgcaaggtctagtgaccgagaagatccagctgttg gaaggcttactggaatcttggtcagaatatgaaaataatgtacaatgtctgaaaacttgg tttgaaacccaggaagagagactgaaacaacaacaccaaattggagaccaggcttctgtt cagaatgcgctgaaagactgtcaggatcttgaagatttgattaaagcaaaagaaaaagaa gtagagaaaattgagcagaacgggcttgctttgattcagaacaagaaagaagaagtgtcc gccactgtcctgtgcacgctgcaggagctcaaccggacctgggcaaatttagagcacatg gcaggacaactaaagatacggttgaagtctgtgcttgaccagtgggaccaacacaaagtg gccttggaagagatgaacagtcacctcatggaggccagatactccctgtcccgattccga ctgctgaccggctccttcgaagctgtgcaggttcaggtagacaatcttcagaatcttcat gatgacttagaaaaacaggaaaggagcttagagaaatttggcgctgtcaccaaccaacta ttaaaagagtgtcacccacctgtgacagaaacgctcaccaatacactgaaagacatcaat atgagatggaataacttgctggaagagattgctgagcagctgcactggagcaaggccctc cttcagctttggcagcgcttcaaagactactctagtcagtgcgcctccacagttcagcag caggaggaacgcaccaatgagctgttgaaggcagccacgaacaaggacatcgctgacaat gaggtggctacgtggattcaagactgcaatgacctccgcaaaggacttgggaccattaaa gactccctcttcattctccatgagctgggagaacaactcaagcagcaagtggatgcttca gcagccgaggccattcagtccgatcagctctccctcagccagcacttgtgcaccctggag caagctctttgcaaacagcagacaatgttacaggctggagttgttgactttgaaaccttt gccaagagtttggaagctctggaggcctggattgtagaagctgaagaggtgctccaaggc caggaccccacccactcgtccgacctctccaccatccaggaaaggatggaagaacttaaa ggacagatgttaaaatttagcagcatggctccagatttagaccgtctcaatgaactgggg tataggttgcccctgaatgacaaggaaatcaagaggatgcagaatctgaactgtctctgg tctctcacctcctctcagactacagaaagatttagtaagttgcagtcatttttgctacaa catcagactttcttggaaaaatgtgagacatggatggaattcctgatacaaacggagcaa aagttagcagtggagatttcaggcaattatcagcatcttttggaacagcagagagcacat gagttgtttcaagctgagatgttcagtcgtcagcagattttgcattcaatcattattgat gggcaacgtcttctagaacaaggtcaagttgatgacagggatgagttcaacttgaaattg accctccttagcaatcaatggcagggtgtgattcgcagggcccagcagaggcgagggatc attgacagccagattcgccagtggcagcgctatagagcgatggcagaaaagctgcgtaaa tggctggtggaagtgtcctacctacccatgaatggtcttggaagtgtccctgtaccattg caacaagtgaggaccctcttcgatgaagtacagttcaaggaaaaagtattcctgcggcag cagggcagctacattctgaccgtggaggccggcaagcagctcctgctctccacggacagc gcagctgaggccgccttgcaggcagaactcactgaaatccaagagaaatggaaatccgcc agcctacatctggaggagcaaaagaaaaaactggccttcttgttgaaagattgggaaaaa tgtgagaaaggagtagctgattctctggagaagctaaaaaatttcaaaaggaagctttct caacctctaccagatcaccatgaggaactccatgcagagcagatgcggtgcaaggaatta gaaaatgcagttgggagctggacagatgacttaacagagctgacactgctgagggggacc ctcgccgcctacatcagtgccgatgacatctccatccttaacgaacgcatagagcttctg cagaggcagtgggaagagctgtgccaccaggtctccttaaggcgacagcaagtaggtgaa agactgaatgaatgggcagtcttcagtgaaaagaacaaggagctctgtgagtggctgacc cagatggaaagcaaagtttcccagaatggagacatcctcattgaggaaatgatagagaag ctcaagaaggattaccaagaggaaattgctgttgcccaggagaacaaaatacagctccag caaatgggagaacgacttgccaaagccagccacgagaccaaagcatctgagattgagtac aagctaggaaaggtcaatgaccgctggcagcatctcctggatctcatcgcagccagggtg aagaagctgaaggagaccttggtggccgtgcagcagctcgataagaacatgagcaaccta cggacttggctcgcccacattgagtcagaactggccaaaccgatagcctacgattcctgt gactcagaagaaatacagagaaagcttaatgagcagcaggagcttcagaaagacattgag aagcacagcacgggtgtcgcctctgtcctcaatctgtgtgaagtcctgctgcatgactgt gatgcttgtgccaccgatgctgagtgtgactccatccagcaggcaacacgaaacctggac cggcggtggagaaacatctgcgctatgtccatggaaaggaggctcaaaattgaagaaaca tggcgactgtggcaaaagtttctggatgactattctcgttttgaagattggttgaagatt tcagaaaggacagctgcttttcccagctcttctggggtgctctatacagttgccaaggaa gaactaaagaaatttgaggctttccagagacaggtccacgagactctgacccagctggag ctcatcaacaagcagtaccgccggctggcccgagagaaccgaactgactcggcgtgcagc ctcaaacagatggttcacgacggcaaccagagatgggacaacctgcaaaagcgtgtcacc tccatcctgcgcagactcaagcattttattagccagcgcgaggagtttgagaccgcacgg gacagcattctggtctggctgacagagatggatctgcagctcactaatattgaacatttt tctgagtgtgatgttcaagctaaaataaaacaacttaaggccttccagcaagaaatttcc ctgaaccacagtaagattgagcagatcatcgcacagggtgagcagctgatagagaagagt gagcctctggatgcggctgtcatcgaggaggagctggatgaactccgccgctactgccag gaggtcttcgggcgcgtggaaagatatcataagaaactgatccgcctgcctctaccggat gatgagcatgacctctctgaccgggagctggagctggatgactctgcagccctctcagac ctgcactggcaggactcatctgtggacggtgtgctctccccccagccttcctccaacccc tccctctcactcccccagcccctgcgcagtgagcggtcaggacgggacaccccggcgagc gtggactctatccccctggagtgggatcatgactatgacctcagtcgtgacctggagtcc gcagtgtccaggactttgcagtctgaggatgaagagggccaggaagagaaggatttctac ctcaggggagcagtcggcttatcagatgtagtgatccccgagagccctgaggcctatgta aaactcacagaaaatgccatcagaaatacctctgggcatcacagcgccttggagtcacag atccaacaactggacaaagccctggatgacagtcgcttccagctgcagcaaactgaaaat gtcctacgcagtagaactcctacggggccagagctagactccagctacaaaggctatatg aaactgctgggcgagtgcagcggcagcatagattcagtgcggaaactggagcacaaactg aaggaggaagaggagaacttccctggctttgttaacttgaatagtactgagatgcagaca gctggtgtgattgaccgatgggagctcctacaggcccaggccctgagcaaggagttgagg atgaagcagaacctccagaaatggcagcagttcaatgcagacctgaacaacatctggacc tggcttggggagacagaggaggaactggaacgactccagcgcctggagctcagcaccgac atccagaccattgagcatcagatcaaaaagctcaaggagctccagaaagcagtggaccac cgcaaagccatcatcctctccatcaacctctgcagctctgagttcactcaggctgacagt aaggagagccaggacctgcgcgatcgcctgtcccagatgaacgggcgctgggacagggtg tgctccttactggaggactggcgggctctgctacaggacgcactcatgcagtgccaggat ttccatgaaatgagccatggtttactgcttatgctggagaatattgacagaagaaaaaat gaaattatccctattgattctcaccttgatacagagatactccaagattatcacaagcag ctgatgcaaatacggcgtgagctgtcagagtctcagctcaaagtgacctcactgcaagac atgtcttgccaactcttggtcaatgctgaaggcactgactgtttggaagccaaagaaaaa gttcatgtcattggaaatcggctcaaacttctcttgaaagaggtcagtcgtcatatcaag gacctggaaaagttactggacatgtcgagcagtcagcaggatttgtcttcctggtcttct gctgatgaactggatacctcgggatctgtgagtcctacgtcaggaagaagtaccccaaac aaacagaaaccgccacgaggcaaatgtagtgtctcacagcctggaccctctgtcagcagt ccaaatagcaggtccacaaaaggtggctccgattcctccctttctgagctgcggccagct cggtcaggccgagccttcctgttccgggtcctccgggcagctttcccccttcagcttctc ctgctgctcctcgtcgggctcgcctgccttgtaccaatgtcagaagaagactacagttgt gccctctccaacaattttgcccgatcattccaccccatgctcagatacacaaacggccct cctccactctga

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