KEGG   Cavia porcellus (domestic guinea pig): 100714724
Entry
100714724         CDS       T07777                                 
Symbol
Akt1
Name
(RefSeq) RAC-alpha serine/threonine-protein kinase
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
cpoc  Cavia porcellus (domestic guinea pig)
Pathway
cpoc01521  EGFR tyrosine kinase inhibitor resistance
cpoc01522  Endocrine resistance
cpoc01524  Platinum drug resistance
cpoc04010  MAPK signaling pathway
cpoc04012  ErbB signaling pathway
cpoc04014  Ras signaling pathway
cpoc04015  Rap1 signaling pathway
cpoc04022  cGMP-PKG signaling pathway
cpoc04024  cAMP signaling pathway
cpoc04062  Chemokine signaling pathway
cpoc04066  HIF-1 signaling pathway
cpoc04068  FoxO signaling pathway
cpoc04071  Sphingolipid signaling pathway
cpoc04072  Phospholipase D signaling pathway
cpoc04140  Autophagy - animal
cpoc04150  mTOR signaling pathway
cpoc04151  PI3K-Akt signaling pathway
cpoc04152  AMPK signaling pathway
cpoc04210  Apoptosis
cpoc04211  Longevity regulating pathway
cpoc04213  Longevity regulating pathway - multiple species
cpoc04218  Cellular senescence
cpoc04261  Adrenergic signaling in cardiomyocytes
cpoc04370  VEGF signaling pathway
cpoc04371  Apelin signaling pathway
cpoc04380  Osteoclast differentiation
cpoc04510  Focal adhesion
cpoc04550  Signaling pathways regulating pluripotency of stem cells
cpoc04611  Platelet activation
cpoc04613  Neutrophil extracellular trap formation
cpoc04620  Toll-like receptor signaling pathway
cpoc04625  C-type lectin receptor signaling pathway
cpoc04630  JAK-STAT signaling pathway
cpoc04660  T cell receptor signaling pathway
cpoc04662  B cell receptor signaling pathway
cpoc04664  Fc epsilon RI signaling pathway
cpoc04666  Fc gamma R-mediated phagocytosis
cpoc04668  TNF signaling pathway
cpoc04722  Neurotrophin signaling pathway
cpoc04725  Cholinergic synapse
cpoc04728  Dopaminergic synapse
cpoc04810  Regulation of actin cytoskeleton
cpoc04910  Insulin signaling pathway
cpoc04914  Progesterone-mediated oocyte maturation
cpoc04915  Estrogen signaling pathway
cpoc04917  Prolactin signaling pathway
cpoc04919  Thyroid hormone signaling pathway
cpoc04920  Adipocytokine signaling pathway
cpoc04922  Glucagon signaling pathway
cpoc04923  Regulation of lipolysis in adipocytes
cpoc04926  Relaxin signaling pathway
cpoc04929  GnRH secretion
cpoc04931  Insulin resistance
cpoc04932  Non-alcoholic fatty liver disease
cpoc04933  AGE-RAGE signaling pathway in diabetic complications
cpoc04935  Growth hormone synthesis, secretion and action
cpoc04936  Alcoholic liver disease
cpoc04973  Carbohydrate digestion and absorption
cpoc05010  Alzheimer disease
cpoc05017  Spinocerebellar ataxia
cpoc05132  Salmonella infection
cpoc05135  Yersinia infection
cpoc05142  Chagas disease
cpoc05145  Toxoplasmosis
cpoc05152  Tuberculosis
cpoc05160  Hepatitis C
cpoc05161  Hepatitis B
cpoc05162  Measles
cpoc05163  Human cytomegalovirus infection
cpoc05164  Influenza A
cpoc05165  Human papillomavirus infection
cpoc05166  Human T-cell leukemia virus 1 infection
cpoc05167  Kaposi sarcoma-associated herpesvirus infection
cpoc05168  Herpes simplex virus 1 infection
cpoc05169  Epstein-Barr virus infection
cpoc05170  Human immunodeficiency virus 1 infection
cpoc05200  Pathways in cancer
cpoc05205  Proteoglycans in cancer
cpoc05207  Chemical carcinogenesis - receptor activation
cpoc05208  Chemical carcinogenesis - reactive oxygen species
cpoc05210  Colorectal cancer
cpoc05211  Renal cell carcinoma
cpoc05212  Pancreatic cancer
cpoc05213  Endometrial cancer
cpoc05214  Glioma
cpoc05215  Prostate cancer
cpoc05218  Melanoma
cpoc05220  Chronic myeloid leukemia
cpoc05221  Acute myeloid leukemia
cpoc05222  Small cell lung cancer
cpoc05223  Non-small cell lung cancer
cpoc05224  Breast cancer
cpoc05225  Hepatocellular carcinoma
cpoc05226  Gastric cancer
cpoc05230  Central carbon metabolism in cancer
cpoc05231  Choline metabolism in cancer
cpoc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
cpoc05415  Diabetic cardiomyopathy
cpoc05417  Lipid and atherosclerosis
cpoc05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cpoc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100714724 (Akt1)
   04012 ErbB signaling pathway
    100714724 (Akt1)
   04014 Ras signaling pathway
    100714724 (Akt1)
   04015 Rap1 signaling pathway
    100714724 (Akt1)
   04370 VEGF signaling pathway
    100714724 (Akt1)
   04371 Apelin signaling pathway
    100714724 (Akt1)
   04630 JAK-STAT signaling pathway
    100714724 (Akt1)
   04668 TNF signaling pathway
    100714724 (Akt1)
   04066 HIF-1 signaling pathway
    100714724 (Akt1)
   04068 FoxO signaling pathway
    100714724 (Akt1)
   04072 Phospholipase D signaling pathway
    100714724 (Akt1)
   04071 Sphingolipid signaling pathway
    100714724 (Akt1)
   04024 cAMP signaling pathway
    100714724 (Akt1)
   04022 cGMP-PKG signaling pathway
    100714724 (Akt1)
   04151 PI3K-Akt signaling pathway
    100714724 (Akt1)
   04152 AMPK signaling pathway
    100714724 (Akt1)
   04150 mTOR signaling pathway
    100714724 (Akt1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100714724 (Akt1)
  09143 Cell growth and death
   04210 Apoptosis
    100714724 (Akt1)
   04218 Cellular senescence
    100714724 (Akt1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100714724 (Akt1)
   04550 Signaling pathways regulating pluripotency of stem cells
    100714724 (Akt1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100714724 (Akt1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100714724 (Akt1)
   04613 Neutrophil extracellular trap formation
    100714724 (Akt1)
   04620 Toll-like receptor signaling pathway
    100714724 (Akt1)
   04625 C-type lectin receptor signaling pathway
    100714724 (Akt1)
   04660 T cell receptor signaling pathway
    100714724 (Akt1)
   04662 B cell receptor signaling pathway
    100714724 (Akt1)
   04664 Fc epsilon RI signaling pathway
    100714724 (Akt1)
   04666 Fc gamma R-mediated phagocytosis
    100714724 (Akt1)
   04062 Chemokine signaling pathway
    100714724 (Akt1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    100714724 (Akt1)
   04922 Glucagon signaling pathway
    100714724 (Akt1)
   04923 Regulation of lipolysis in adipocytes
    100714724 (Akt1)
   04920 Adipocytokine signaling pathway
    100714724 (Akt1)
   04929 GnRH secretion
    100714724 (Akt1)
   04915 Estrogen signaling pathway
    100714724 (Akt1)
   04914 Progesterone-mediated oocyte maturation
    100714724 (Akt1)
   04917 Prolactin signaling pathway
    100714724 (Akt1)
   04926 Relaxin signaling pathway
    100714724 (Akt1)
   04935 Growth hormone synthesis, secretion and action
    100714724 (Akt1)
   04919 Thyroid hormone signaling pathway
    100714724 (Akt1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100714724 (Akt1)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    100714724 (Akt1)
  09156 Nervous system
   04725 Cholinergic synapse
    100714724 (Akt1)
   04728 Dopaminergic synapse
    100714724 (Akt1)
   04722 Neurotrophin signaling pathway
    100714724 (Akt1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100714724 (Akt1)
  09149 Aging
   04211 Longevity regulating pathway
    100714724 (Akt1)
   04213 Longevity regulating pathway - multiple species
    100714724 (Akt1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100714724 (Akt1)
   05205 Proteoglycans in cancer
    100714724 (Akt1)
   05207 Chemical carcinogenesis - receptor activation
    100714724 (Akt1)
   05208 Chemical carcinogenesis - reactive oxygen species
    100714724 (Akt1)
   05230 Central carbon metabolism in cancer
    100714724 (Akt1)
   05231 Choline metabolism in cancer
    100714724 (Akt1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100714724 (Akt1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100714724 (Akt1)
   05212 Pancreatic cancer
    100714724 (Akt1)
   05225 Hepatocellular carcinoma
    100714724 (Akt1)
   05226 Gastric cancer
    100714724 (Akt1)
   05214 Glioma
    100714724 (Akt1)
   05221 Acute myeloid leukemia
    100714724 (Akt1)
   05220 Chronic myeloid leukemia
    100714724 (Akt1)
   05218 Melanoma
    100714724 (Akt1)
   05211 Renal cell carcinoma
    100714724 (Akt1)
   05215 Prostate cancer
    100714724 (Akt1)
   05213 Endometrial cancer
    100714724 (Akt1)
   05224 Breast cancer
    100714724 (Akt1)
   05222 Small cell lung cancer
    100714724 (Akt1)
   05223 Non-small cell lung cancer
    100714724 (Akt1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100714724 (Akt1)
   05170 Human immunodeficiency virus 1 infection
    100714724 (Akt1)
   05161 Hepatitis B
    100714724 (Akt1)
   05160 Hepatitis C
    100714724 (Akt1)
   05164 Influenza A
    100714724 (Akt1)
   05162 Measles
    100714724 (Akt1)
   05168 Herpes simplex virus 1 infection
    100714724 (Akt1)
   05163 Human cytomegalovirus infection
    100714724 (Akt1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100714724 (Akt1)
   05169 Epstein-Barr virus infection
    100714724 (Akt1)
   05165 Human papillomavirus infection
    100714724 (Akt1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100714724 (Akt1)
   05135 Yersinia infection
    100714724 (Akt1)
   05152 Tuberculosis
    100714724 (Akt1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100714724 (Akt1)
   05142 Chagas disease
    100714724 (Akt1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100714724 (Akt1)
   05017 Spinocerebellar ataxia
    100714724 (Akt1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100714724 (Akt1)
   05418 Fluid shear stress and atherosclerosis
    100714724 (Akt1)
   05415 Diabetic cardiomyopathy
    100714724 (Akt1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100714724 (Akt1)
   04932 Non-alcoholic fatty liver disease
    100714724 (Akt1)
   04931 Insulin resistance
    100714724 (Akt1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100714724 (Akt1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100714724 (Akt1)
   01524 Platinum drug resistance
    100714724 (Akt1)
   01522 Endocrine resistance
    100714724 (Akt1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cpoc01001]
    100714724 (Akt1)
Enzymes [BR:cpoc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     100714724 (Akt1)
Protein kinases [BR:cpoc01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   100714724 (Akt1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PH Pkinase_C Kinase-like PH_20 PH_11 Seadorna_VP7
Other DBs
NCBI-GeneID: 100714724
NCBI-ProteinID: XP_003463160
Ensembl: ENSCPOG00000004489
UniProt: A0A286XKS8
LinkDB
Position
Unknown
AA seq 480 aa
MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDMDQRESPLNNFSVAQC
QLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKRQEEELMEF
QSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI
LKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS
RERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI
KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
ILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFASIVWQDVYEKK
LSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDNMECVDSERRPHFPQFSYSASGTA
NT seq 1443 nt   +upstreamnt  +downstreamnt
atgagtgacgtggccattgtgaaggagggctggctgcacaagcgaggggagtacatcaag
acctggcggccgcgctacttcctcctcaagaatgatggcaccttcatcggctacaaggag
cggccgcaggacatggaccagcgtgagtcccctctcaacaacttctctgtggcacaatgc
cagctgatgaagacggagcggcccaggcccaacaccttcatcatccgctgcctgcagtgg
accacagtcattgagcgcacgttccacgtggagacacctgaggagcgggaggagtggacc
actgccatccagacagtggccgatggtctcaagaggcaggaggaggagctgatggagttc
cagtcaggctcgcccagcgacaactcgggggctgaggagatggaggtgtctctggccaag
cccaagcaccgtgtgaccatgaacgagtttgagtatctgaagctgctgggcaagggcacc
ttcgggaaggtgatcctggtgaaggagaaggccactggccgctactatgccatgaagatc
ctcaagaaggaggtcatcgtggccaaggacgaggtggcccacacactcactgagaaccgt
gttctgcagaactccaggcaccccttcctcacggccctgaagtactccttccagactcat
gaccgcctctgcttcgtcatggagtacgccaatggtggtgagctcttcttccacctgtcc
cgagagcgtgtgttctcggaggaccgggcccgcttctacggtgcggagattgtgtcggct
ctggactacctgcactcggagaagaacgtggtgtaccgggacctcaagctggagaacctc
atgctggacaaggacgggcacatcaagattacagattttgggctctgcaaggagggcatc
aaggacggtgccaccatgaagaccttctgcgggacgcccgagtacctggcccctgaggtg
ctggaggacaacgactatggccgtgcggtggactggtgggggctgggtgtggtcatgtat
gagatgatgtgcggccgcctgcccttctacaaccaggaccacgagaagctgttcgagctc
atcctcatggaggagatcagattcccacgcactctgggccccgaggccaagtccctgctc
tcagggctgctcaagaaggaccccaagcagaggcttggtgggggctccgaggacgccaag
gagatcatgcagcaccgcttcttcgccagcattgtgtggcaagacgtgtatgagaagaag
ctcagcccgcccttcaagccacaggtcacctcagagactgataccaggtattttgacgaa
gagttcacagcccagatgatcaccatcaccccacctgaccaagatgacaacatggagtgt
gtggacagtgaacggaggccacacttcccacagttctcctactcggccagcggtacagcc
tga

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