Cavia porcellus (domestic guinea pig): 100715532 Help Entry 100715532         CDS       T07777                                  Symbol Adcy4 Name (RefSeq) adenylate cyclase type 4   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism cpoc  Cavia porcellus (domestic guinea pig) Pathway cpoc00230   Purine metabolism cpoc01100   Metabolic pathways cpoc01522   Endocrine resistance cpoc04015   Rap1 signaling pathway cpoc04020   Calcium signaling pathway cpoc04022   cGMP-PKG signaling pathway cpoc04024   cAMP signaling pathway cpoc04062   Chemokine signaling pathway cpoc04072   Phospholipase D signaling pathway cpoc04081   Hormone signaling cpoc04082   Neuroactive ligand signaling cpoc04114   Oocyte meiosis cpoc04211   Longevity regulating pathway cpoc04213   Longevity regulating pathway - multiple species cpoc04261   Adrenergic signaling in cardiomyocytes cpoc04270   Vascular smooth muscle contraction cpoc04371   Apelin signaling pathway cpoc04540   Gap junction cpoc04611   Platelet activation cpoc04713   Circadian entrainment cpoc04714   Thermogenesis cpoc04723   Retrograde endocannabinoid signaling cpoc04724   Glutamatergic synapse cpoc04725   Cholinergic synapse cpoc04727   GABAergic synapse cpoc04742   Taste transduction cpoc04750   Inflammatory mediator regulation of TRP channels cpoc04911   Insulin secretion cpoc04912   GnRH signaling pathway cpoc04913   Ovarian steroidogenesis cpoc04914   Progesterone-mediated oocyte maturation cpoc04915   Estrogen signaling pathway cpoc04916   Melanogenesis cpoc04918   Thyroid hormone synthesis cpoc04921   Oxytocin signaling pathway cpoc04923   Regulation of lipolysis in adipocytes cpoc04925   Aldosterone synthesis and secretion cpoc04926   Relaxin signaling pathway cpoc04927   Cortisol synthesis and secretion cpoc04928   Parathyroid hormone synthesis, secretion and action cpoc04934   Cushing syndrome cpoc04935   Growth hormone synthesis, secretion and action cpoc04970   Salivary secretion cpoc04971   Gastric acid secretion cpoc04972   Pancreatic secretion cpoc04976   Bile secretion cpoc05032   Morphine addiction cpoc05163   Human cytomegalovirus infection cpoc05166   Human T-cell leukemia virus 1 infection cpoc05200   Pathways in cancer cpoc05207   Chemical carcinogenesis - receptor activation cpoc05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:cpoc00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100715532 (Adcy4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100715532 (Adcy4)    04371 Apelin signaling pathway     100715532 (Adcy4)    04020 Calcium signaling pathway     100715532 (Adcy4)    04072 Phospholipase D signaling pathway     100715532 (Adcy4)    04024 cAMP signaling pathway     100715532 (Adcy4)    04022 cGMP-PKG signaling pathway     100715532 (Adcy4)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     100715532 (Adcy4)    04081 Hormone signaling     100715532 (Adcy4)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100715532 (Adcy4)   09144 Cellular community - eukaryotes    04540 Gap junction     100715532 (Adcy4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100715532 (Adcy4)    04062 Chemokine signaling pathway     100715532 (Adcy4)   09152 Endocrine system    04911 Insulin secretion     100715532 (Adcy4)    04923 Regulation of lipolysis in adipocytes     100715532 (Adcy4)    04912 GnRH signaling pathway     100715532 (Adcy4)    04913 Ovarian steroidogenesis     100715532 (Adcy4)    04915 Estrogen signaling pathway     100715532 (Adcy4)    04914 Progesterone-mediated oocyte maturation     100715532 (Adcy4)    04921 Oxytocin signaling pathway     100715532 (Adcy4)    04926 Relaxin signaling pathway     100715532 (Adcy4)    04935 Growth hormone synthesis, secretion and action     100715532 (Adcy4)    04918 Thyroid hormone synthesis     100715532 (Adcy4)    04928 Parathyroid hormone synthesis, secretion and action     100715532 (Adcy4)    04916 Melanogenesis     100715532 (Adcy4)    04925 Aldosterone synthesis and secretion     100715532 (Adcy4)    04927 Cortisol synthesis and secretion     100715532 (Adcy4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100715532 (Adcy4)    04270 Vascular smooth muscle contraction     100715532 (Adcy4)   09154 Digestive system    04970 Salivary secretion     100715532 (Adcy4)    04971 Gastric acid secretion     100715532 (Adcy4)    04972 Pancreatic secretion     100715532 (Adcy4)    04976 Bile secretion     100715532 (Adcy4)   09156 Nervous system    04724 Glutamatergic synapse     100715532 (Adcy4)    04727 GABAergic synapse     100715532 (Adcy4)    04725 Cholinergic synapse     100715532 (Adcy4)    04723 Retrograde endocannabinoid signaling     100715532 (Adcy4)   09157 Sensory system    04742 Taste transduction     100715532 (Adcy4)    04750 Inflammatory mediator regulation of TRP channels     100715532 (Adcy4)   09149 Aging    04211 Longevity regulating pathway     100715532 (Adcy4)    04213 Longevity regulating pathway - multiple species     100715532 (Adcy4)   09159 Environmental adaptation    04713 Circadian entrainment     100715532 (Adcy4)    04714 Thermogenesis     100715532 (Adcy4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100715532 (Adcy4)    05207 Chemical carcinogenesis - receptor activation     100715532 (Adcy4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100715532 (Adcy4)    05163 Human cytomegalovirus infection     100715532 (Adcy4)   09165 Substance dependence    05032 Morphine addiction     100715532 (Adcy4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100715532 (Adcy4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100715532 (Adcy4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100715532 (Adcy4) Enzymes [BR:cpoc01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100715532 (Adcy4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N CD52 Motif Other DBs NCBI-GeneID:  100715532 NCBI-ProteinID:  XP_003474436 Ensembl:  ENSCPOG00000014412 LinkDB All DBs Position Unknown AA seq 1077 aa AA seqDB search MARLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLAVVLCGLLALLAVAWATARELTSDPG FLTTVLCALGGFSLLLGLASREQRLQRWTRSLSGLVWAALLALGQGFVFTGGIVSAWDQV SFFLFIIFTVYAMLPLGMWEAAAAGLTSSLSHLLVLGLYLGPQPDSQPALLPQLAANAVL FLCGNVVGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK AEIMARLQTGQESQPENTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAVNCVRMGLDMCRAIRKLRAATG VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEASGVPGRVHITGATLTLLAG AYAVEDAAMEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLFSLEGHKMRPSLLMTR YLQSWGAAKPFAHLSHIDNPVSTSTPLPEKALASFSPQWSLDRSWTPRGLDDELDTGDAK FFQVIEQLNSQKQWKQSKDFNLLTLYFREKEMEKQYRFSALPAFKYYTACAFLVFVSNFI IQMLVTNRPPALAFTYSITFLLFLLLLFICFSEHLTWCIQKGPKMLHWLPALSGLVATQP GLRVALGTATILLIFTMAIASLFFLPASADCPFQTPSVSSVGFNLSWELPGSLPLISVPY SMHCCVLGFLSCSLFLHMSFELKLALLLLWLTASCSIFLYSHAWLSDCLIAHLYLSPLDS RPGVLKEPKLMGAISFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEQEETETMENLTRL LLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLR LLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDAQQDAERSCSHLGTMV EFAVALGSKLDVISKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMEST GVLGKIQVTEETAQALQSLGYTCYSRGVIKVKGKGQLCTYFLNTDLARTGPPSATLG NT seq 3234 nt NT seq  +upstreamnt  +downstreamnt atggcccgcctcttcagcccccggccgccccccagcgaggacctcttctacgagacctac tacagcctgagccagcagtacccgctgctgctgctgctgctcgccgtcgttctctgcggg ctcctggcgctgctcgctgtcgcctgggccaccgccagggagctgacgtcagacccaggc ttccttaccacagtgttatgcgccttgggtggcttctcgctgctgctgggcctagcttcc cgggagcagcgactgcagcgctggacacggtcactgtctggccttgtgtgggctgcactg ctggctctaggccagggcttcgtgtttactgggggcatcgtgagtgcctgggaccaggtg tccttcttcctcttcatcatcttcactgtgtatgccatgctgcccttgggcatgtgggaa gctgccgctgcaggcctcacctcctcactctcacacttactggtcctcggactctacctt gggccacagccggactcccaacctgcgctgctgccacagttggcagccaatgcagtgctg ttcttgtgtgggaatgtggtgggggcgtaccacaaggcactgatggagcgcgcactgcgt gccaccttccgggaggcactcagctccctgcactctcgccggagactggacacagagaaa aagcaccaggaacacttgctcctgtccatccttcctgcctacctggcccgagagatgaaa gcagagatcatggcacggctacaaactggacaggagtcccagccagagaacaccaataac ttccacagcctctatgtgaagaggcaccaaggagtcagtgtgctgtatgctgacatcgtg ggcttcacacggctggccagcgagtgctctccaaaggagctggtgctcatgctcaatgag ctcttcggaaagtttgaccagatcgccaaggagcacgaatgcatgcggatcaaaatcctg ggagactgctactactgcgtctccgggctgccactatcattgcctgaccatgccgtcaac tgcgtgcgcatggggctggacatgtgccgtgccatcaggaaattgcgtgcagccactggt gtggatatcaacatgcgtgtgggcgtgcactctggcagtgtgctttgtggagtcatcggg ctgcagaagtggcagtatgacgtctggtcccatgatgtcacactggccaatcacatggag gcgagcggtgtaccagggcgggtgcacatcacaggggctaccctgaccctgttggcaggg gcctatgctgtggaggacgcagccatggaacaccgagacccataccttcgggagctaggg gagcctacgtacctggtcatcgatcctcgggctgaggaagaggatgagaagggcaccgca ggagggttactgttctctctggaaggccacaagatgcgcccatcactgctgatgacccgc tatctgcagtcttggggtgcagctaagccttttgcccacctgagccacatagacaatcct gtgtccacctccactcctctcccggagaaggccctggcttccttcagcccccagtggagc ctggaccggagctggaccccccggggactggatgatgagctggacactggggatgccaag ttcttccaggtcatcgaacagctcaactctcagaaacagtggaagcagtcgaaggacttc aacttactgacactgtacttcagagagaaagaaatggaaaaacagtatcggttctcggct ctccctgccttcaaatactacacagcctgcgccttcttagtttttgtgtccaacttcatc atccaaatgctggtaacgaacaggcccccagctctggcctttacttacagcatcaccttc ctcctcttccttctccttctcttcatctgcttctcagagcacctgacgtggtgtatccag aaaggtcccaagatgctgcactggctgcctgcactgtctggcttagtagccacacagcct ggactgcgagtagctctgggtactgccaccatccttctcatctttaccatggccattgcc agcctgttcttcttaccagcatccgcagactgccctttccagacccccagtgtgtcctcc gtgggtttcaacctgtcctgggagctgcctgggtcactgcctctcatcagtgtcccgtac tccatgcactgctgtgtgctgggtttcctctcctgttccctctttctgcacatgagcttt gaactgaagctggcgctgctcctgctgtggctgacggcttcctgctccatcttcctgtac tcccatgcctggctgtcagactgcctcatcgcccacctctacctaagtcccttggactcc aggccaggagtcctgaaagaaccaaagctgatgggagccatctccttcttcatcttcttc ttcaccctcctggtcctggctcggcagaatgaatattactgccgcctggacttcctgtgg aagaagaaactgaggcaggagcaggaagagacagagacaatggagaacctgacccggctg ctcttggagaatgtgcttcctgcacatgtggccccacagttcattggccagaaccggcgc aatgaggacctctaccaccagtcctatgagtgtgtttgcgtgctcttcgcctcagtccca gactttaaggagttttattctgaatccaacatcaaccatgaagggctagagtgtctgcgg ctgcttaatgagataattgctgattttgatgagctgctttccaagcccaagttcagtgga gtagagaagatcaaaactattggcagtacctacatggcagccacaggtttaaatgccacc tctggacaagatgcacaacaggatgctgagcgaagctgcagccaccttggcaccatggtg gaatttgcagttgccctggggtccaagctggatgttatcagcaagcactcattcaacaac ttccgactgcgtgtggggttgaaccatggaccagtggtggctggagtgattggggctcag aagccacagtatgatatctggggcaacacagtgaacgtggccagtcgcatggagagcaca ggagtccttggcaagatccaggtaactgaggaaacagcccaggccctgcagtccctgggc tatacatgctacagtcgaggtgtcatcaaggtcaaaggcaaaggacagctctgcacctac tttctgaatacagacttggcacgaactggacctccctcagccactctaggctga

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