Cavia porcellus (domestic guinea pig): 100716463 Help Entry 100716463         CDS       T07777                                  Symbol Syne2 Name (RefSeq) nesprin-2 isoform X1   KO K19346   nesprin-2 Organism cpoc  Cavia porcellus (domestic guinea pig) Pathway cpoc04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:cpoc00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     100716463 (Syne2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:cpoc03036]     100716463 (Syne2) Chromosome and associated proteins [BR:cpoc03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     100716463 (Syne2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  CH Spectrin_SYNE1 KASH Spectrin SYNE1 CAMSAP_CH NPV_P10 Terminase_7 Motif Other DBs NCBI-GeneID:  100716463 NCBI-ProteinID:  XP_013010648 Ensembl:  ENSCPOG00000005654 LinkDB All DBs Position Unknown AA seq 6923 aa AA seqDB search MASSPVLPVDNEQVSSGIDDLHISLQAEQEDTQKKTFTCWINSQLAKHTPPSVISDLFTD IRKGHVLLDLLEVLSGQQLPRDKGSNTFQCRINIEHALTFLKNQSIKLINIHVTDIVEGN PSIILGLIWTIILHFHIEELTQTLSGSYSQPPVDDVSVPDSPAASSPPAKKCSTAQARWQ LSAKKALLVWAQECCASHESISVTDFKSSWRNGLAFLAVIHALRPDLIDMKCVKHKSNKD NLKEAFTIAERELKIPRLLEPEDVDTVNPDEKSIMMYVAQFLQYSKNAPVIRSKAQSKVE DAVAWLTLQEEKLQQVQKDTANETYYNKYQRLLSFVESLNEEKKSFLDLLSLKGNAQELS EDQRLLTEGWNGLHCQINAWKTKLEDALPPPLRDTQACLREVEELAEEALSASQDSSDPV ALTQEKMTVFKNLMDRFDYHSNILLTFENKDEKDLPLVPPDKLEEMRRRLNNILEKKFIL LLEFHYHKRSVLGLLDEVKSKLDVWNIKYGNRESVELLLEDWHKFIEEKEFLTQLEASFQ RCGEIYKNLAGEYETINEQYMIMEQNVCMYRKNIENVKSALQKVLACWATYLENLRSLKA YFEDTKKEQVTEVPFEMLSQWNADHTTLNEVGHLLIEVSNDEVGSSISKELRRLNKRWRK FITKTPLEMKLPLTKKRDEPIPEDSGTSLPFKQEKLPVDFSMDTAVEAPENHNQNVKAME DYERENEESPEQLKVSEEVEKLTGQVEIWEAETRSVLDLLRHQDAMDSSLEEALQHLSAR GSMYEELLARTEDALQMDVQNISGPESLQHVLTGGLQAKIQEANEKIQITMVKLVTALKN SADACPDSDSKQRMEETQQEFELSVRKAEQLLAQRESQSELISKYKEALKIHNANSLVKY LKAIEELKPSVSEAAKLSLEEKSRVARAKWESLHHEISLYIQQLKIDIEKGKLNDTIAKL EKQINKEKKLIRRGKSKGLIKEHEACFGTDGIVGQLDHHTGILRELSEELDSQERQQEVK RALRDYEQKIERLLKSAAEVLTMLKAPAGGSSKVQGTMTATENGGKDSHSKGLIAKSDNQ PSAAKASEAMEPIKNFNQALELKPQGEENVEKNGKDDNASVNKLQERYDTQKEILELHLQ NNKFRITSDFSDEKEWRSACLQDKLKDLQLLKKETDAYWKEFEIASLTLESLVSDTEKPI IVKARDTLKGKENDFQMPLKTRLESLELALQVALPVEESLLLCDLDLALREVAVQEFHLM DADSVYQNLRNIQDSIAKQIAICHDLEEPGNSVLKGLHPTDIGATQNIVLKCRTQLEQTS HRMQMAKDVLAALEDFLSSVAAVKLSKELFTDPSAPDAQGAPGTTVTKRDMEEEIRLMSN KARQLDKRLKKLGISFKDAERGGDSTCEKLVDAVSTELLDTQGPGTRQELAEENKLLEAC SSKNNELFKNIQDVQKQMSEIGLKDPTVPAVKHRKKSLIKLEKDLDGYAAEKKHLEEMAS SLPQFKDGREKILNEQCQNTVLLWDSTKTAVTECLEQCGRVLELLKQYQNFKSVLTTLIQ KEETIISQQASYMGKENLRKRMAEIEIVKEEFNEHLEVVDKINQICKNLQFHLNKMKTFE EPPFEKEANVIVDRWLDINEKTEEYYENLGRALALWDKLFNLKNFIDEWTEETLQKMGSH LLTEEDRERLKEELRMHEKQTSEFSKRVAEIQFLLQSSEKPLELQVMESSVWNKMEHVKK CVTGEASSCALGGSQAELREDLDQAKTQIGMTESLLKALSPSDSLEIFTKLEEIQQQILQ QKHSMIILENQIGCLTPELSELKKQYESVSDLFNTKKSALQDHFSALLNDQCKNFNDWFS NIEMNLKDCFEPSETKKSVQHKLQKLSEFLSLEGRGGKIQQVETVLQHVKKHLPKARVKE LSSWLVSQEFQLEKMESICQARARELDSDLQQLLRLEDDCGNLSKWLINQEEKWKETGES GEKAELFRQALARKREQFESVAQLSSFLKERGLEEEEVIMQSTHLMGRYQTFLRQLGRTE EEPQLPSEEGQSFDDLAHGVIHWIKEIKESLMALNSSEGKMPLEERIQKIKEIILLKPEG DARIQAIMRQAQGCEALAGQVQEMVADIREQWDSTQHLASTYLSHQEKLLQEGEKYLQSK EDLRLMLTELRKKQEAGFALQHGLQEKKAQLKIYKKFLQKAQDLTSLLEELKSQGNYLLE CTKNPSFSEEPWLEIKHLHESLLQQLQDSVQTLEGHVQEHHSYQVCVTDLNTTLDSFSRE FVSFSDTPVNQTAIEDKLQKLQELESRLRLQDGTLKKILALAKSIKPNTSSVGQKIIKDD IKSLKHKQKDLENRIALAKRETENCLNSLLKSKRSAEKQENSAALNGEARATSDALESTQ GSTAEGKSEGDWDINKNSAVEMVLSKQLSLSVQESMKSIDDEQKVNELRNQPLELDTLLR NEQLRAIEELYAQLEAKKEAIDSLAQSKCLHDSETSALGPHKARCSPHHLDSLLQALTAL KKNKESQYSLLQDFQERLAALESSMTASLAGEGSLKVGALDSETYLNKIKKFLELIEKEK GSLVDLQVQWETLSEHMTDMDKKLLGSQMKRLERGWEHLAHLAQKKYSQHTAECDEFASL RSKIRDTEISLQQQQQQLLLGLKSPEDQDGSQSIVTLAAELQAARRGFTAVRSRAEVQMK RLWGEKEKKILEDAIQNLKKQFEALEPLNLEVESQIKKCDLKSKMKETLLWIRNLLSELT LPISLLPDNILFQIRKCKVMHDSILDKQQAMESLAEEVLAEVPNLTTPERDNVNSILQDL QNQYQMLVLQSTQRSQQLEFKLEERSKLFEMMKEAQLTLEGHEALLVPKTEAPPTEAELE HHHATLRASQKGLQEVESLISARLRELTDASEDLSVFERLFLDNHLNNLKTRVSRIQRCI QSKCNEVEHKISSYREFHERESMLQKEVDMVQHNKLLLHLETNQDAKEEFQHFKERLAGV RRSILDVLKLREVFDHIGLNWDGSQLDQLQTQVFEKEKELEEKIKQLNIFMAEHGKYQAS LSQMRAMNLQIKKKAELVLKSPPPLPENDLLNAQILIEKIDKAKCLHNDIIKKLSENKAF DDSFKEKEIAQLQLVTEENKKLHKLLQTLVLEFQPKEVDEKHFQDKLENSLHVLHGIKSQ LEQPLLINLDIDHMQNEKDNCEAFQDQVHAEMYSIKAMTPPENQRGENSSETSDTEAKLH DLEDLQMQLSKSIDLRTNVLDSAYENFTCYSEAVSRAMEILGSLEAMFVSCRVDLHNPEE ALTRSGWKQEELESIITVIEDLTEKLGSVSSPEAKMQLEHTLQDLLSKRLTLQEAAKAEQ AKIARCLEDYKGYRSSKEEICAGLQRAETALGLAMVLLPASYKEALERLEQSKALVSELL STKEELMQLRRVAGRLSGCCTQGDGVSTLRAASALWDRWLCVLEAAQEWAMWSEDLKQDW KFISEEVEREAIILENLQEELPEMSKMKEAASTEALSEALASLCQYEESVEEQELLLRLL LQRMQGIRNVLEGSDATGMVPAHQEIAAMRERCCRLLQKVQNNKELIQTEIQERLNFTKE IIALKMLFQQSTNAFQNMASEGRPQRAEQLEELQSFVEKGKLTFGNIMEKLRIKYSEMYT IVPAEVESQMEECRKVLEDIDEKISGEGLRSSPSCVTGRKIEEINSGLQQVEQMLQQKSK NIEKAQDIQKKMWDELDLWHSKLNELDSEVQDIVEQDPGQAQEWMDKLMVPFQKYQQVSQ RAEARTSQLNKATVKMEEYSDLLRSTEAWIENTSRLLVSPAHCDSSKTLSQHASALQMAL EDSEQKHNLLHSVFTDLEDLSIIFETDDLVQSIQELSSQVTALQQQIVESLPHIQRVADD VVAIESEVKSMEKKVSKIKTILLSKEIFDFSPEEHLKHGEVILGNLRPMKKTIAEIVSYQ VELQLPQPEVNPLPVFQRTNQLLQDVKLLENVTQEQNELLKIVIKQTNECDEEIENLKQI LSDYAAEFSLGHTSPDQATDLPAVQEEIEAVEKQVLRLNQKKEDLLVDLKAAILTLHEHL KQDQQEAERAGQSATTSEDRAAEREALEWKRDRTGSMSFLPAVEEEAEESPVQSEDGCEE ARPSAGSQPFLWEQDEDLEGNGAASSSATVIQEAERKISTCDRSMMQILAPDSPVTEQDP EFSAGLSQTGDAATLPTEAAALDFAVEQGPLRPTVEPAEPRPAEVLHVCQTQVAKLELWL QQASVAFEPETLNTDMQQVVEQELVGCQAMLTEIEQKVASLLETCKDQCLGDSGTIQHEA EVLSLKLRTVKCNLEKVQMMLQEKYSEDQFPTILKKPSEHLKFLRPVHLSELEFIVTERP QFSRLKDVPQPQVLELKPMEQRDLIKFIEFNAKKTWPQDCQQDGSTTQESSTRGKASDSE NEAPDSTSASQGQRSSDKWQYLLHKLASRRRLPPPQVVEPQITTGVGVLPSVRVCSFKYP TIEELKTYTTLLEDLRQEANDLQTQENVTAEPYVSLDKKLFDLCLTLSQCLGSVEELLQT PGLLREDTHSQQAHCEELALELKKLYLALGDKKDDLLKAVTWPGKNASLFLDCFNDLQLY LEHVQAKAAWRSKSLKAGLDYTHSYQNEIKRLYDHLIKSKTALQQSLNEISGQSIGDQLQ KADAYTAELQKSENRVAKLRDEGERLGFPSTVLQEVHKLEDILDSMWGILRARYLELSSP FNSESQLDALLQGLGELVSIGQEKLVQGHLQQAKSKAALQAQLQSHKVFFQKLVADMLLI QTYSAKMFPSLLQKREAFWAEQVSEIKSLEDKAQQCGVKLQSLLQKWEEFDENYASLEKD LEILVSTFPSVNLVEETEERLMERISLYQQIKRNIEGKHARLYQTLSEGRQLAACVSCPE LEGQIARLEEQGLALSRKTDHELHRLQTLLKHLLSYNRDSDELTKWLESSQQTLNYWKEQ SLNVSQDLDTIRSNIKKFFDFSKEVDEKSSLKSAVVSTGNQLLHLKEADAATLRAALAQF EQKWTLLITQLPDIQEKLHQLQMEKLPSRKAITEMISWMDNVEHQMAAEDSVCAPSSASQ VKRLLRKLKEFRMEMDYKQWIVDFVNQSLLQLSTCDVESKRYERTEFAEHLGEMNRQWHR VHGTLNGKIQHLEQLLESITEHENKIQILNNWLEAQEERLKTSEKPASVLSIEKLLLDCQ DIENQLAIKSKALEELRQSHLTLESGATPWLEDPASGVDGFFQKRSSVLDEVARLRASVQ SVLAAQKTCEKLYEEVCGTVVRFRYRAEHSKPETPSLEALASQVQTLQCLQDEAESSEGN WEKLQEVTAKLKESCPSVAEIIEEKCQHTRARWTQVNQDLADELQRASGLLQLWKAYHSA HTEVTAKLEQQEAKFQQLSKINTSGNNLAETLPLALQDIQELQHHVQKTKEAVLQNSTLL ERLPQPAETSVPELLSGQQHALQRAAYLEKMLLMKASEFEFVLSQFKEFGDQLESLQDLI IREEENLDKLYQLEKEENPDSFLNHVLALTAQAPAIERLNEVSLRLPLSDVAVKTLQQVN RQWVRATATALDRCSELQGIGLNEKFLRYCEKWVLLLERSEEALRENVANSLPALREQQK TLEMLEAEVSISQPIADSYITQSLQLLDTTEIEKRPEFVLEFSKLVDRWQSVGQGIWQRK CEVTGRVQQQQSFSTATEDLLRFLGATSLLLSAVKGQDRYSLLQTRELTQELKNKEIHFQ RQQTTYALAVEVGEKLLNTLDQETQESVDRRISQLRDSWDDTKRQLGLLLKQLQSTGETW DQCERKIKELKSRLQVLKAQSKNPLPELHEDLQKEKELIKDLEKSLANWSQNLKELHTMK ADLAAHVLAEDTMALKEQIEHLHRQWEDLCLRVAARKQEIEDRLSSWIVFNEKNKELCAW LVQMENKVLQTADISIEEMIEKLQKDCMEEINLFSENKLQFKQMGDQLIKASNTARAAEI NDKLHKINDRWQHLFDVIGSRVKKLKETFAFIQQLDGNMSNLRTWLARIESELSKPVVYE VCDDQEIQKRLAEQQDLQRDIEQHSAGVESVFNICDVLLHDSDACANETECDSIQQTTRS LDRRWRNICAMSMERRMKIEETWRLWQKFLDDYSRFEDWLKSAERTAACPNSSEVLYTSA KEELKRFEAFQRQIHERLTQLELINKQYRRLARENRTDTASRLKQMVHEGNQRWDNLQRR VTAVLRRLRHFTNQREEFEGTRESILVWLTEMDLQLTNVEHFSESDADDKMRQLDGFQQE ITLNTNKIDQLIVFGEQLIQKSEPLDAALIEDELEELHRYCQEVFGRVSRFHRRLTARTP GLEEEKEASENETDMEDPREIQADAWRKRGESEEPTSPQSLCHLMPPTLGHERSGCETPV SVDSIPLEWDHTGDVGGSSSHEEDEEGPYYSAVSDVEIPENPEAYLKMTTKALRASSGKS ISDSHSWHVPDSPSPAKHRYKQMEEDRSEPPIPSDASTPYKQPYVKLLQPRIHGGKEGAR VLNGSHQQEEEQQLASAAGQQSGAFDTWELIQAQELHSKHRIKQNMQQLNSVISDITAWL EKTEAELEALKMAKPPSDIQELELRVKRLQEIVKAFDTYKTLMVSVNVSAKESLPSESAE ASELHHRLCQLNLHWETAQGKMDSWRETLRQSLLQCQDFHQRSQSLLLWLASAEEQRQKA LVTDPKADHQDLLRCQKQLMQLEKELAECQPHVNSLHELSTSLLVKGNGEDYIEAEEKVH VIKKKLQQLREQVARDLLSLQRSQNPDPALPDFDEVDSGDQPPAASAPAPQAKQFLAEGI TEDEDNSDGRVSGPAGPSSTKPRRSFLSRVIRAALPLQLLLLLLLLLACLLPASEEDYSC TQANNFARSFYPMLSYTNGPPPT NT seq 20772 nt NT seq  +upstreamnt  +downstreamnt atggcatctagtcctgtgcttcccgtggacaatgagcaggtttcctccggcattgatgac ctccacatctccctgcaagctgaacaggaagacacacagaagaaaaccttcacctgctgg ataaattcacagttggcaaagcacacgcctccctcggtcatatcagacttattcacagac attagaaagggccatgttctcctcgacctgttagaagtactctcaggacagcagttgcct cgagataaaggatctaatacattccaatgtagaatcaatatagaacatgccctgacattc ctaaaaaatcaatcaatcaagctaataaatattcatgttactgatattgtggaaggaaac ccatccattattcttggcctaatttggaccattatactgcactttcatatcgaggagctc acccagacgctttctggcagttacagtcaacctcctgtggatgacgtgagtgtgccagat tcacctgctgcttcaagtccaccggctaagaaatgctccacagcccaagcacggtggcag ctgtccgcaaagaaagcccttctcgtgtgggcccaggagtgctgtgcctcgcatgagtcc atcagcgtgacagattttaagtcaagctggagaaatgggctggcctttttggctgtcatt catgccttgcgaccagacctaattgatatgaagtgtgtgaagcataaatccaacaaggac aatctgaaagaggccttcacaattgcagaacgagaattgaaaatccccagattgctggaa cccgaagatgtagacactgttaatcctgatgaaaagtccatcatgatgtacgtggcacag tttctacagtattccaagaatgcacctgtgattagaagtaaagcgcagagcaaggtggaa gatgccgtggcctggctcaccctgcaagaggaaaagctacagcaggtgcaaaaggacaca gcaaatgagacctactataataagtatcagagactgctgtcctttgtggaatcattgaat gaagaaaaaaaatccttcctggacctcctgtccctgaaagggaatgcccaggagctgagt gaagatcagagactgctgacagaaggctggaatggtctccactgccagattaacgcctgg aaaaccaagctggaggacgccttgcccccacccctgcgtgacacccaagcctgcctgcgg gaggtggaggagctggcagaggaagccttgtcagcctcccaggattcctctgaccccgtg gctctgacccaggaaaaaatgactgtgtttaagaatctgatggacagatttgactatcat tcgaacattctcctgacctttgaaaataaagacgagaaagatttgccgctggtaccgcct gacaaattggaggaaatgagaagacgactcaacaacattttggagaaaaaatttattcta cttctagaatttcattaccataagcgttcagttcttggtttgctagatgaagtgaaatcc aaattggatgtctggaacatcaaatatgggaacagagaatctgtggaattattgctggaa gactggcataaatttattgaagaaaaagagttcctgactcaacttgaagcttcttttcaa agatgtggagaaatttataagaatttggctggtgaatatgaaactattaatgaacaatac atgattatggaacagaatgtttgtatgtacagaaaaaatatagagaatgtgaaatcagct ttgcaaaaagtcctggcatgttgggctacttacttggaaaaccttcgttcattaaaggct tactttgaggacacaaagaaggaacaagttacagaggtcccctttgagatgctctcccag tggaacgcagaccacaccactttaaatgaagtggggcatttgctaattgaagtcagcaat gatgaggtgggatcatctatttctaaagaactgagaagactgaataaaagatggagaaag tttatcacaaaaaccccactcgaaatgaaactaccacttacaaaaaaaagggatgagccc attcctgaagattctggaactagtctaccatttaaacaagaaaaactgcctgttgatttt tcaatggataccgcagtagaagctcctgaaaatcacaatcagaatgtaaaggccatggaa gattatgaacgagaaaatgaagaatccccagaacaactgaaagtgtctgaagaggttgaa aaactcactggacaagtggaaatctgggaggcagaaaccagatctgtcttggatcttctg agacatcaagatgccatggatagctccttggaagaggctttgcagcatctcagtgccaga ggctctatgtatgaagaacttctggccagaactgaagatgctttacaaatggatgttcag aatatttcagggccagagtctctccaacatgtcctcacgggtggccttcaagcaaagatt caagaagctaatgagaaaatacagatcaccatggtaaaactggtcacagcactgaagaac tcagcagatgcatgcccagactcagacagcaagcagaggatggaagagacccagcaggag tttgagttgtctgtgaggaaagcggaacagttacttgcacaaagagagagccagagtgag ctcatctccaaatacaaggaagcactaaaaattcataatgcaaatagtctggtcaagtat ttgaaagccattgaagaactgaagcccagtgtctccgaggctgcaaagctgtctctggaa gagaagagtagagttgcccgcgccaagtgggagtcacttcatcatgaaatttctttgtat attcaacaactaaaaatagacattgaaaaaggaaaacttaacgatactattgcaaaactt gaaaagcaaataaataaagaaaagaaacttattcgtagaggaaagagcaagggtctcatt aaggaacatgaggcttgctttggtactgatggcatcgtgggccagcttgatcaccacact ggcatcctgagggagctgagtgaagagctggattcgcaggagaggcaacaggaagtgaag agagcgctcagagactatgaacagaagatagaaagacttctgaagagcgctgctgaggtt ctcacaatgctgaaggcccccgcgggaggttcatcgaaagtccagggaaccatgaccgca actgagaatggcggaaaggattcccatagcaaggggctgattgcaaaatcagataatcag ccatcagctgcaaaggcatcagaggcaatggaacccattaagaatttcaaccaagccttg gagttaaagccccagggagaagaaaatgtggaaaagaatggaaaggatgataatgcatct gtaaataagctacaagagaggtatgatacacaaaaagaaattcttgaactccatctgcag aacaacaaattcaggattacttctgatttttctgatgaaaaggaatggaggagtgcttgt ctgcaggataagctgaaagatctgcagctcttaaaaaaggaaactgatgcttactggaaa gagtttgaaattgcctcattgacattagaaagcctcgtgagtgacacggagaaacctatt atagttaaggcaagagatacattaaagggaaaagaaaacgactttcaaatgcctcttaaa accagattggagtcccttgagctggcactgcaggtggcgttgcccgtggaggagtcactg ctgctgtgtgacttggacctggcgctcagggaggtggctgtccaggaatttcatctcatg gatgccgacagtgtttaccaaaacctgaggaatatccaggattccattgcaaaacagatt gcgatatgtcatgatttagaagagccaggcaactctgtgttaaagggattacaccccact gacataggcgccacgcagaacattgtgctaaaatgcagaactcagcttgagcaaacaagc cacaggatgcagatggctaaggatgtcctggccgccctggaggacttcttgtcttctgta gcagccgtaaagctctccaaggaacttttcacagacccatcagccccagatgcacagggg gcaccaggaactactgtaacaaaaagagatatggaagaagaaattcggctgatgagcaac aaggccagacagctggacaagcgcttaaagaagcttggcatcagctttaaagatgctgag cgaggtggagattccacttgtgaaaaacttgtagatgctgtgtccacagagttactagac acacagggccctggcacacggcaggaactggctgaggagaacaaactattagaggcctgt agctccaaaaataatgagctctttaaaaatatccaagatgtgcagaagcagatgagtgaa attggccttaaggatcccaccgtcccagctgtgaagcatcggaaaaaatccttaatcaag ctggagaaggatctagatggatatgcagcagagaaaaaacacttggaagaaatggccagt tctcttccacagttcaaagatggcagagaaaaaattctgaatgaacagtgccagaatact gtcctcttgtgggatagcacaaaaactgctgtcactgagtgtcttgaacagtgtggaaga gttctggagctcttgaagcagtatcagaattttaaaagtgtcttgacaactttgattcaa aaagaagagacgatcatctcgcagcaggcttcgtacatgggcaaggagaacctgaggaag cggatggccgagattgaaattgtcaaagaagaattcaatgaacacttagaagtggtagat aaaattaaccagatctgtaaaaatctacaatttcatctgaataaaatgaaaacttttgaa gagcctccttttgaaaaagaggctaatgttattgtggacagatggcttgatataaatgaa aagacagaagaatactatgaaaatcttggtcgagctctggctttatgggacaaacttttt aacttaaaaaatttcattgacgaatggactgaagagactcttcaaaaaatgggctcacac ctgctgacggaagaggacagagaacggctgaaggaagagttacgaatgcatgaaaaacaa acatcagaattttctaaaagagtggccgaaattcagtttctgcttcaaagtagtgaaaag ccgcttgaacttcaggtcatggagtcgtctgtttggaataagatggaacatgtgaaaaag tgtgtaaccggagaagccagcagctgcgcactcggcgggagccaggctgagctgagggag gatctggaccaagccaagacccagatcgggatgaccgagtccctcttgaaagcactgtct ccttctgacagcttggagatcttcaccaaactcgaggagatacagcagcaaattctacag cagaagcacagcatgataatccttgaaaatcaaataggttgtctcactccagaactctct gaattgaaaaagcaatatgaaagtgttagtgatttattcaataccaaaaagagtgctttg caagatcacttttctgcattattgaatgatcagtgcaagaactttaacgactggtttagc aacattgaaatgaaccttaaggactgttttgaaccatcagaaacaaagaagagtgtgcag cacaagctacagaaactttctgagttcctgagtcttgaaggaagaggcgggaaaatacag caggtagaaacagtgctgcagcatgtgaagaagcacctgcccaaagctcgcgtgaaggaa cttagcagctggctcgtgagtcaggaattccagttagaaaagatggagtccatatgccag gctcgagctcgggagctcgacagcgacctgcagcagctgctgagactggaggatgactgt ggaaacctgagcaagtggttgattaatcaagaagagaaatggaaagaaacaggagaatca ggagagaaagctgagctgttccgccaagctctggccagaaagagggaacagtttgaatct gtggcccagttgagcagctttttgaaggaacgtggcctcgaggaagaagaagtcataatg cagtcaacacatctgatggggagataccagaccttcctgagacagctggggagaaccgag gaagagcctcagttaccgtccgaggagggccagagctttgacgatctcgcacatggtgta attcattggataaaggagattaaagagtcgcttatggctttgaattcatccgaaggcaaa atgccactggaagaaagaatccaaaaaataaaggaaatcattctactcaaacctgaaggg gatgccagaatacaggccatcatgaggcaggcgcagggttgcgaggccctggcagggcag gtccaggagatggtggccgatatccgtgagcagtgggacagcacacagcacttggccagc acgtacctgagtcatcaagaaaagcttctacaagaaggagaaaagtacttgcaaagtaaa gaagacctgagattaatgctcacagagctcaggaagaaacaggaagctggctttgccctg cagcatggcctgcaggagaagaaagctcagttaaaaatttataagaaattcctccagaaa gcccaagatttgacgtccttgctagaggagttaaagtctcaaggaaactacctgttggaa tgcactaaaaaccccagctttagcgaagagccctggctagagataaaacatctgcacgaa agcctccttcagcaactacaggattctgtgcaaacgttggagggtcatgttcaagaacac cactcataccaggtttgcgtcacagacttgaataccacgttggacagtttttcgagggaa tttgtcagtttttctgatacacctgtgaatcaaacagccattgaggacaaattgcagaaa ctgcaggaactagagagtagactccgtttacaagatggcaccttaaagaagattttagcg ttagcgaaatccatcaagccaaacacatcttcagtgggacagaagattattaaagatgat ataaaatcacttaagcataaacaaaaagatttggaaaacaggattgcgcttgccaagcgg gagactgaaaattgtctcaacagccttctcaaatcaaaacgttcagcagagaagcaagag aactcagctgcactgaacggagaggcgcgggccacttctgatgcgctggagtccactcag ggctccacggcggagggaaagtctgagggagactgggacataaacaagaattcagctgtg gaaatggttttgtcaaaacaactttctctcagtgttcaagaaagcatgaaaagcattgac gacgagcagaaagtcaatgagctgcgaaatcaacctttagagttagacactctgttaaga 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cagtttagcagattaaaagatgtcccacagccacaggttctagagttaaagccaatggaa cagagagatttaatcaaattcatagaatttaatgctaagaaaacatggccacaggattgc caacaggatggaagtaccactcaggaatcatctacaaggggcaaagcatccgactctgag aacgaagccccagactccacctccgcctcgcagggccagcgcagcagtgacaaatggcag tatcttcttcacaagctggcatcgaggaggcggctgccaccgcctcaggtcgtggagccc cagattaccacaggagtaggtgttctacccagtgtacgtgtgtgtagcttcaaataccct acgattgaagagctgaaaacctatactaccctactggaagacctgcgccaggaagctaat gaccttcagacacaggaaaatgtgacagcagagccatatgtcagtttggacaagaagtta tttgacctctgcttgacgctcagtcagtgcctggggagtgtggaggagctgctgcagacc ccagggctgctgcgggaggacacgcacagccagcaggcacactgcgaggagctggctctt gagctgaagaaactgtatttggctctgggtgacaagaaggacgatcttttgaaagctgtg acgtggcctggcaagaatgctagtttgttccttgactgtttcaatgacctccaactctac ctggagcatgtacaggcaaaggctgcctggaggagcaagtccctgaaagctggcctcgac tacacccacagctatcagaatgaaataaaacgattgtatgatcacctcatcaagagtaag acagcccttcagcagtctttgaatgagatcagtggccagagtattggtgaccagctccag aaagcagatgcatacacagcagagctgcaaaagtctgagaatcgagtggccaaactcaga 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caacttctgcacctcaaagaggcagacgccgctacgctgagagctgctttagcacagttt gaacaaaaatggacactgctcatcactcagcttccagatattcaagaaaagcttcaccag cttcagatggagaaattgccatctcgtaaagcaatcacagaaatgattagctggatggac aatgtggaacatcaaatggcggctgaagattctgtgtgcgccccaagttctgcatctcaa gtgaaaagacttcttcggaagcttaaggagtttagaatggaaatggactacaaacagtgg atcgttgactttgttaaccagtcactacttcagttaagcacgtgtgatgtagaaagcaag cgctacgaaagaacggagtttgcagagcacctgggcgagatgaaccgccagtggcaccgg gtccacgggaccctgaacggaaagatacaacatttagaacaacttttagaaagcatcact gagcatgaaaacaaaatacagatcttgaacaactggttggaggcacaggaagagaggcta aagacttctgagaaacctgccagtgtgctgtccattgagaagctgctcctggactgtcag gacatagaaaaccaactcgcgattaaatccaaagccctggaggagttgaggcaaagccat ctgactctggagagtggggccacaccgtggttagaagatccggcatctggagttgatggg ttcttccagaagaggagcagtgtgctggatgaggtcgcccggctcagggcctctgtacag tcagtgctggcggcccagaagacctgcgagaagctctatgaggaggtgtgtggcactgta gtccggttcaggtaccgcgcagagcatagcaagcccgagacgccatccctggaggccctg gcgagccaggtgcagacgctgcagtgtcttcaagatgaagctgagagcagtgaggggaat tgggagaaactgcaggaggtcaccgccaaactcaaagagtcctgcccctcggttgccgaa ataatcgaagagaaatgccagcacactcgtgcaaggtggacccaggtaaaccaagacctt gcagatgagctgcagagggccagcgggctactccagctctggaaggcctatcacagtgcc catacagaagtcacagccaagctggagcagcaggaagccaagtttcaacagctttcaaaa atcaacacatctggaaacaacctggcagagaccctaccactggccctgcaggacatacag gagctgcagcaccacgtgcagaagaccaaagaagccgtgctccagaattccaccctgctg gagcggctcccacagcctgcggagaccagtgtccctgagctcctttccgggcagcagcat gccctccagagagctgcttatttggaaaagatgctgcttatgaaagccagtgaattcgag tttgttctttcacagttcaaggaatttggagaccagctggaatctttacaggatcttatt atacgtgaggaagagaatttggataaactttaccagctagaaaaagaagaaaatcctgac tcattcctgaatcatgtgctggcgctgacagcccaggctcctgccatcgagcgtctgaat gaagtcagcctcaggctcccgctcagtgatgtggccgtgaagactttgcagcaggtgaac cggcagtgggtccgggccacagccactgccctggaccgctgcagtgagcttcagggaatt ggactcaatgaaaagtttcttcgttactgtgaaaagtgggtcctcctgttggagaggtca gaagaggcgctcagagagaatgttgccaacagccttccagctctccgggagcagcagaaa acactggagatgttagaagctgaagtttctataagccagcccattgctgattcttacatt 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